---
title: Comparison of Maternal Hemodynamics During Spinal Anesthesia with Different Cesarean Delivery Positioning
nct_id: NCT06857162
overall_status: NOT_YET_RECRUITING
phase: NA
sponsor: Aswan University
study_type: INTERVENTIONAL
primary_condition: This Study Aims to Provide Evidence on Which Positioning Strategy Offers the Best Hemodynamic Outcomes
countries: Egypt
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT06857162.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06857162"
ct_last_update_post_date: 2025-03-19
last_seen_at: "2026-05-12T06:14:25.385Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Comparison of Maternal Hemodynamics During Spinal Anesthesia with Different Cesarean Delivery Positioning

**NCT ID:** [NCT06857162](https://clinicaltrials.gov/study/NCT06857162)

## Key Facts

- **Status:** NOT_YET_RECRUITING
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 216
- **Lead Sponsor:** Aswan University
- **Collaborators:** Aswan University Hospital
- **Conditions:** This Study Aims to Provide Evidence on Which Positioning Strategy Offers the Best Hemodynamic Outcomes, Maternal Hemodynamic, Maternal Positioning During CS
- **Start Date:** 2025-04-25
- **Completion Date:** 2025-09-01
- **CT.gov Last Update:** 2025-03-19

## Brief Summary

Cesarean delivery is a common surgical procedure, and maintaining maternal hemodynamic stability during the procedure is crucial for both maternal and fetal outcomes . Hemodynamic instability, such as hypotension following spinal anesthesia, is a frequent complication and can lead to adverse maternal and neonatal outcomes. Traditionally, after spinal anesthesia, women are positioned supine, sometimes with a slight left lateral tilt to mitigate the risk of aortocaval compression . However, recent studies and clinical observations suggest that delayed supine positioning-keeping the patient in a sitting or semi-sitting position for a period following spinal anesthesiamay improve hemodynamic stability. These alternative positions may help to mitigate the abrupt drop in blood pressure commonly seen after spinal anesthesia by allowing for a more gradual redistribution of blood volume . Understanding the optimal positioning strategy could lead to improved clinical protocols that enhance maternal and fetal safety. By comparing immediate supine positioning with delayed supine positioning (in sitting and semi-sitting positions), this study aims to provide evidence on which positioning strategy offers the best hemodynamic outcomes.

## Eligibility

- **Minimum age:** 20 Years
- **Maximum age:** 40 Years
- **Sex:** FEMALE
- **Healthy Volunteers:** Yes

```
Inclusion Criteria:

* Pregnant women scheduled for elective cesarean delivery.
* Age between 18 and 40 years.
* ASA (American Society of Anesthesiologists) physical status II.

Exclusion Criteria:

* Emergency cesarean delivery.
* Pre-existing cardiovascular disease.
* Severe preeclampsia or eclampsia.
* Multiple pregnancies.
* Known fetal anomalies.
```

## Arms

- **Group A (N=72): Immediate Supine Position** (ACTIVE_COMPARATOR)
- **Group В (N=72): Sitting Position** (EXPERIMENTAL)
- **Group С (N=72): Semi-Sitting Position** (EXPERIMENTAL)

## Interventions

- **Positioninng during Cs** (BEHAVIORAL) — 1. Group A (N=72): Immediate Supine Position (Control):

   Immediately after administering spinal anesthesia, participants will be placed in a supine position. To reduce the risk of aortocaval compression, a slight left lateral tilt (approximately 15 degrees) will be applied. This is the traditional positioning method and serves as the control group for comparison.
2. Group В (N=72): Sitting Position:

   After spinal anesthesia, participants will be positioned in a sitting position with the ack supported at a 90-degree angle for the first 2 minutes. Knees will be bent, and feet will be supported.
3. Group С (N=72): Semi-Sitting Position:

After spinal anesthesia, participants will be positioned in a semi-sitting position with the back supported at the back supported at for the first 2 minutes.

Similar to the sitting position, knees and feet will be flat.

## Primary Outcomes

- **To compare the incidence and severity of hypotension in immediate supine, sitting, and semi-sitting positions during cesarean delivery.** _(time frame: 9 Months)_

## Locations (1)

- Aswan University Hospital, Aswān, Aswan Governorate, Egypt

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `sponsor.collaborators` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.aswan university hospital|aswān|aswan governorate|egypt` — added _(2026-05-12)_

---

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