---
title: Changes of Higher-Order Aberrations After Different Types of LASIK in Myopia
nct_id: NCT06860061
overall_status: NOT_YET_RECRUITING
phase: NA
sponsor: Sohag University
study_type: INTERVENTIONAL
primary_condition: Conventional LASIK, Femto-LASIK and PRK in Low and Moderate Myopia
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT06860061.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06860061"
ct_last_update_post_date: 2025-03-05
last_seen_at: "2026-05-12T07:03:09.885Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Changes of Higher-Order Aberrations After Different Types of LASIK in Myopia

**Official Title:** Changes of Corneal and Total Ocular Higher-Order Aberrations After Conventional LASIK, Femto-LASIK and PRK in Low and Moderate Myopia

**NCT ID:** [NCT06860061](https://clinicaltrials.gov/study/NCT06860061)

## Key Facts

- **Status:** NOT_YET_RECRUITING
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 60
- **Lead Sponsor:** Sohag University
- **Conditions:** Conventional LASIK, Femto-LASIK and PRK in Low and Moderate Myopia
- **Start Date:** 2025-03
- **Completion Date:** 2026-02
- **CT.gov Last Update:** 2025-03-05

## Brief Summary

This prospective comparative interventional study will enroll patients with low and moderate myopia who seek laser vision correction at Sohag Center for LASIK and Corneal Surgeries, Sohag, Egypt. Eyes included will be divided into 3 groups according to the type of refractive surgery used (conventional LASIK, Femto-LASIK and PRK) and each group will be subdivided into 2 groups according to the degree of myopia (low and moderate).

## Eligibility

- **Minimum age:** 18 Weeks
- **Maximum age:** 45 Weeks
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

Age: 18 - 45 years old.

Refraction:

Low and moderate grades of myopia will be included:

(According to manifest refraction) low (\[0\] - ≤ \[-3\] diopters) Moderate (\[-3\] - ≤ \[-6\] diopters) With cylinder ≤ \[-1.5\] diopters.

Exclusion Criteria:

Any ocular surgery or medication, corneal opacities, pregnancy, lactation and keratoconus.
```

## Arms

- **group 1** (ACTIVE_COMPARATOR) — Conventional Lasik
- **group 2** (ACTIVE_COMPARATOR) — Femto LASIK
- **group 3** (ACTIVE_COMPARATOR) — PRK

## Interventions

- **Laser refractive surgery** (PROCEDURE) — This prospective comparative interventional study will enroll patients with low and moderate myopia who seek laser vision correction at Sohag Center for LASIK and Corneal Surgeries, Sohag, Egypt. Eyes included will be divided into 3 groups according to the type of refractive surgery used (conventional LASIK, Femto-LASIK and PRK) and each group will be subdivided into 2 groups according to the degree of myopia (low and moderate).

All patients will be subjected to routine comprehensive preoperative examinations including manifest uncorrected distant visual acuity (UCDVA), best corrected distant visual acuity (BCDVA), slit-lamp examination, intraocular pressure, and fundus examination.

Corneal topography and corneal aberrometry will be performed on all patients using Sirius's Scheimpflug-Placido topography (CSO, Florence, Italy). The CSO topography system analyzes a total of 6144 corneal points of a corneal area within a circular annulus outlined by an inner radius of 0.33 mm and an outer

## Primary Outcomes

- **Changes of corneal higher-order aberrations** _(time frame: 1 year)_ — Corneal aberrometry will be performed using Sirius's Scheimpflug-Placido topography (CSO, Florence, Italy).
- **Changes of total ocular higher-order aberrations** _(time frame: 1 year)_ — Wavefront refraction will be acquired by the iDesign aberrometer (Hartmann-Shack Aberrometer)

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT06860061.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT06860061*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*