---
title: Chronic Mouth Breathing and SARS-CoV-2 Positivity in the Pediatric Population
nct_id: NCT07063134
overall_status: COMPLETED
sponsor: Dokuz Eylul University
study_type: OBSERVATIONAL
primary_condition: SARS-CoV-2 Infection
countries: Turkey (Türkiye)
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT07063134.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT07063134"
ct_last_update_post_date: 2025-07-14
last_seen_at: "2026-05-12T06:35:26.413Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Chronic Mouth Breathing and SARS-CoV-2 Positivity in the Pediatric Population

**Official Title:** Investigation of the Relationship Between Chronic Mouth Breathing and SARS-CoV-2 Positivity in the Pediatric Population

**NCT ID:** [NCT07063134](https://clinicaltrials.gov/study/NCT07063134)

## Key Facts

- **Status:** COMPLETED
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 173
- **Lead Sponsor:** Dokuz Eylul University
- **Conditions:** SARS-CoV-2 Infection
- **Start Date:** 2022-03-02
- **Completion Date:** 2022-05-02
- **CT.gov Last Update:** 2025-07-14

## Brief Summary

Numerous non-scientific articles on the internet assert the significance of nasal breathing in protecting against COVID-19. Although nasal breathing is anticipated to result in a reduced intake of bioparticles when compared to mouth breathing due to the filtering mechanisms present in the nasal cavity, we have yet to identify any in vivo studies within the literature that definitively ascertain the correlation between mouth breathing and COVID-19 positivity. Consequently, this study aimed to investigate the impact of chronic mouth breathing on testing positive for COVID-19 in children.

## Detailed Description

Objective Coronavirus disease (COVID-19) is an infectious respiratory illness caused by the SARS-CoV-2 virus. Breathing patterns may influence the transmission of respiratory diseases. Mouth breathing inhaled pollutants and pathogens directly into the lungs. Therefore, this research investigated the impact of chronic mouth breathing on COVID-19 positivity in children.

Materials and Methods A total of 173 patients aged between 10 and 17 years, without any systemic diseases or COVID-19 vaccinations, who were undergoing COVID-19 testing, were included in the study. The age, gender, simplified oral hygiene index, and respiratory models of the included patients were assessed. Patients with a specific malocclusion caused by mouth breathing were diagnosed as "mouth breathers" through clinical assessments. Those who tested positive for COVID-19 were assigned to the experimental group, while those who tested negative were designated as the control group. The differences in mouth breathing rates, simplified oral hygiene index, and sociodemographic data (sex and age) between groups were statistically analysed. Subsequently, the relationship between mouth breathing and the Delta variant was examined.

Results No statistically significant differences were found in sex, breathing pattern, and the simplified oral hygiene index, except for age (p\>0.05). The average age of the patients in the experimental group was lower. The Delta variant was more common among chronic mouth breathers (p\<0.05).

Conclusion Chronic mouth breathing heightens the risk of transmission, as the pathogenicity of COVID-19 viruses increases.

Clinical relevance Healthcare professionals should possess the knowledge necessary to identify individuals who breathe through their mouths, as this group faces a heightened risk of contracting respiratory diseases.

## Eligibility

- **Minimum age:** 10 Hours
- **Maximum age:** 18 Hours
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* tested for COVID-19

Exclusion Criteria:

* Not tested for COVID-19
```

## Arms

- **COVID-19 Positive Group** — Participants who tested positive for SARS-CoV-2 by PCR at the time of evaluation.
- **COVID-19 Negative Group** — Participants who tested negative for SARS-CoV-2 by PCR at the time of evaluation.

## Primary Outcomes

- **Rate of COVID-19 Positivity in Chronic Mouth Breathers Compared to Nasal Breathers** _(time frame: At 2 weeks post-COVID-19 recovery")_ — Proportion of COVID-19 positivity among chronic mouth breathers compared to nasal breathers

## Locations (1)

- Usak University Faculty of Dentistry, Izmir, Turkey (Türkiye)

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.usak university faculty of dentistry|izmir||turkey (türkiye)` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT07063134.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT07063134*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*