---
title: Spartina® (Tirzepatide) Effectiveness and Safety Evaluation
nct_id: NCT07262762
overall_status: RECRUITING
sponsor: Cinnagen
study_type: OBSERVATIONAL
primary_condition: Obesity & Overweight
countries: Iran
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT07262762.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT07262762"
ct_last_update_post_date: 2025-12-16
last_seen_at: "2026-05-12T06:14:26.785Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Spartina® (Tirzepatide) Effectiveness and Safety Evaluation

**Official Title:** A Post-marketing Real-world Study for Evaluating Effectiveness and Safety of Spartina® (Tirzepatide Manufactured by CinnaGen) in Patients With Obesity and Overweight

**NCT ID:** [NCT07262762](https://clinicaltrials.gov/study/NCT07262762)

## Key Facts

- **Status:** RECRUITING
- **Study Type:** OBSERVATIONAL
- **Target Enrollment:** 175
- **Lead Sponsor:** Cinnagen
- **Conditions:** Obesity & Overweight
- **Start Date:** 2025-11-11
- **Completion Date:** 2026-04
- **CT.gov Last Update:** 2025-12-16

## Brief Summary

The goal of this study is to evaluate Effectiveness and safety of Spartina® (Tirzepatide) in male or female participants with obesity and overweight. The main questions which are aimed to be answered:

1. Is Spartina® (Tirzepatide) effective in the treatment of obesity and overweight?
2. Is Spartina® (Tirzepatide) safe in the treatment of obesity and overweight?

In this study, there is no comparison group. Participants receive Spartina® (Tirzepatide)

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL
- **Healthy Volunteers:** No

```
Inclusion Criteria:

1. Male or female ≥18 years of age
2. Willingness for signing and having signed the informed consent form
3. BMI ≥30 kg/m² or ≥27 kg/m² with ≥1 weight-related comorbidity

Exclusion Criteria:

1. Prior use of any GLP-1 agonist in the last 6 months
2. Type 1 diabetes mellitus
3. Any condition or circumstance that might pose a risk to the subject or interfere with the ability to acquire satisfactory clinical data
4. Pregnancy or breast-feeding
5. Personal or family history of medullary thyroid carcinoma (MTC) or patients with multiple endocrine neoplasia syndrome type 2 (MEN 2)
```

## Primary Outcomes

- **Proportion of patients with ≥5% weight loss** _(time frame: day 0, 180)_

## Secondary Outcomes

- **Percent change in body weight from baseline** _(time frame: day 0, 90)_
- **Absolute change in body weight from baseline** _(time frame: day 0, 90)_
- **Percent change in body weight from baseline** _(time frame: day 0, 180)_
- **Absolute change in body weight from baseline** _(time frame: day 0, 180)_
- **Mean change in Body Mass Index from baseline** _(time frame: day 0, 90, 180)_
- **Mean change in waist circumference from baseline** _(time frame: day 0, 90, 180)_
- **Proportion of patients with ≥5% weight loss** _(time frame: day 0, 90)_
- **Proportion of patients with ≥10% weight loss** _(time frame: day 0, 90, 180)_
- **Proportion of patients with ≥15% weight loss** _(time frame: day 0, 180)_
- **Assessment of the adverse events (including Treatment Emergent Adverse Events)** _(time frame: during study period)_
- **Assessment of immunogenicity at screening** _(time frame: day 0, 90, 180)_

## Locations (14)

- Akbar Aliasgarzadeh Clinic, Tabriz, East Azerbaijan Province, Iran — _RECRUITING_
- Dr. Mohammadhossein Dabbaghmanesh Clinic, Shiraz, Fars, Iran — _RECRUITING_
- Behrang Motamed Clinic, Rasht, Gilan Province, Iran — _RECRUITING_
- Seyed Mojtaba Mehrdad Clinic, Rasht, Gilan Province, Iran — _RECRUITING_
- Mansoor Siavash Dastjerdi Clinic, Isfahan, Isfahan, Iran — _RECRUITING_
- Sari Diabetes Research Center, Sari, Mazandaran, Iran — _RECRUITING_
- Shokoofeh Bonakdaran Clininc, Mashhad, Razavi Khorasan Province, Iran — _RECRUITING_
- Alireza Esteghamati clinic, Tehran, Tehran Province, Iran — _RECRUITING_
- Farzad Hadaegh Clininc, Tehran, Tehran Province, Iran — _RECRUITING_
- Imam Khomeini Hospital, Tehran, Tehran Province, Iran — _RECRUITING_
- Iran University Endocrinology Research Center, Tehran, Tehran Province, Iran — _RECRUITING_
- Mohammadreza Mohajeri Tehrani Clininc, Tehran, Tehran Province, Iran — _RECRUITING_
- Khorshid Clinic, Yazd, Yazd Province, Iran — _RECRUITING_
- Hajieh Bibi Shahbazian Clinic, Ahvāz, Iran — _RECRUITING_

## Recent Field Changes (last 30 days)

- `locations.sari diabetes research center|sari|mazandaran|iran` — added _(2026-05-12)_
- `locations.seyed mojtaba mehrdad clinic|rasht|gilan province|iran` — added _(2026-05-12)_
- `locations.mansoor siavash dastjerdi clinic|isfahan|isfahan|iran` — added _(2026-05-12)_
- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.akbar aliasgarzadeh clinic|tabriz|east azerbaijan province|iran` — added _(2026-05-12)_
- `locations.dr. mohammadhossein dabbaghmanesh clinic|shiraz|fars|iran` — added _(2026-05-12)_
- `locations.behrang motamed clinic|rasht|gilan province|iran` — added _(2026-05-12)_
- `locations.shokoofeh bonakdaran clininc|mashhad|razavi khorasan province|iran` — added _(2026-05-12)_
- `locations.alireza esteghamati clinic|tehran|tehran province|iran` — added _(2026-05-12)_
- `locations.farzad hadaegh clininc|tehran|tehran province|iran` — added _(2026-05-12)_
- `locations.imam khomeini hospital|tehran|tehran province|iran` — added _(2026-05-12)_
- `locations.iran university endocrinology research center|tehran|tehran province|iran` — added _(2026-05-12)_
- `locations.mohammadreza mohajeri tehrani clininc|tehran|tehran province|iran` — added _(2026-05-12)_
- `locations.khorshid clinic|yazd|yazd province|iran` — added _(2026-05-12)_
- `locations.hajieh bibi shahbazian clinic|ahvāz||iran` — added _(2026-05-12)_

---

*Canonical: https://parkinsonspathways.com/agent/trials/NCT07262762.md*  
*Source data (authoritative): https://clinicaltrials.gov/study/NCT07262762*  
*This page is a raw mirror with no AI summary, no editorial enrichment, and no Parkinson's-specific filtering.*