---
title: Effects of Core Stabilization Exercises in Female Patients With Gonarthrosis
nct_id: NCT07482332
overall_status: RECRUITING
phase: NA
sponsor: Cumhuriyet University
study_type: INTERVENTIONAL
primary_condition: Knee Osteoarthritis (Knee OA)
countries: Turkey (Türkiye)
canonical_url: "https://parkinsonspathways.com/agent/trials/NCT07482332.md"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT07482332"
ct_last_update_post_date: 2026-03-19
last_seen_at: "2026-05-12T06:37:11.914Z"
source: ClinicalTrials.gov (mirrored, no enrichment)
---
# Effects of Core Stabilization Exercises in Female Patients With Gonarthrosis

**Official Title:** Randomized Controlled Study of the Effects of Core Stabilization Exercises in Addition to Knee Exercises in Female Patients With Gonarthrosis

**NCT ID:** [NCT07482332](https://clinicaltrials.gov/study/NCT07482332)

## Key Facts

- **Status:** RECRUITING
- **Phase:** NA
- **Study Type:** INTERVENTIONAL
- **Target Enrollment:** 40
- **Lead Sponsor:** Cumhuriyet University
- **Conditions:** Knee Osteoarthritis (Knee OA)
- **Start Date:** 2026-01-05
- **Completion Date:** 2026-09-14
- **CT.gov Last Update:** 2026-03-19

## Brief Summary

Osteoarthritis (OA) is a non-inflammatory degenerative disease characterized by progressive deterioration of cartilage tissue, synovial membrane, and joint capsule, primarily affecting weight-bearing joints. Individuals with knee osteoarthritis exhibit weakness in the trunk and periarticular muscles. This loss of strength in the trunk and periarticular muscles increases the load on the joint, contributing to the development and progression of the disease. This study aimed to investigate the effects of core stabilization, applied in addition to knee muscle exercise programs, on clinical symptoms and functional capacity in individuals with knee osteoarthritis.

## Detailed Description

Osteoarthritis is the most common chronic joint disease and a leading cause of disability worldwide. It represents a significant public health and cost problem due to reduced work productivity and early retirement. OA is a non-inflammatory degenerative disease characterized by progressive deterioration of cartilage tissue, synovial membrane, and joint capsule, particularly in weight-bearing joints, along with a series of biochemical and morphological changes. While its etiology is not fully understood, it is considered a multifactorial disease involving a combination of systemic and regional factors. Increased bone density, joint laxity, and excessive mechanical loading are some of these factors. Symptoms of knee osteoarthritis include pain, joint stiffness, swelling, loss of function, and muscle weakness. Pain and joint stiffness in individuals negatively affect daily living activities such as climbing stairs, walking, and running, leading to decreased functionality. Current literature emphasizes that strong proximal trunk stabilization is needed for safe and effective completion of movements in the distal segments, and that weakness in this region is directly related to lower extremity pain. This study aimed to investigate the effects of core stabilization, applied in addition to an exercise program for the knee muscles, on clinical symptoms and functional capacity in individuals with knee osteoarthritis.

## Eligibility

- **Minimum age:** 45 Years
- **Maximum age:** 65 Years
- **Sex:** FEMALE
- **Healthy Volunteers:** No

```
Inclusion Criteria:

* Kellgren-Lawrence 2-3 knee osteoarthritis
* Female patient aged 40-65
* Volunteer

Exclusion Criteria:

* Having received physical therapy within the last month
* Presence of neurological, cardiac, and respiratory problems
* Less than 90 degrees of flexion in the knee and hip joints
* Presence of any pathology in the lower extremity that may affect balance and function
* History of lower extremity surgery
* Severe visual, hearing, and speech impairment
* Illiteracy in Turkish
* Body mass index of 30 or higher
```

## Arms

- **Experimental Group** (EXPERIMENTAL) — This group will receive 10 days of conventional physiotherapy (Hot Pack, TENS, Ultrasound) and 6 weeks of routine knee exercises + 6 weeks of core stabilization exercises.
- **Control Group** (OTHER) — This group will receive 10 days of conventional physiotherapy (Hot Pack, TENS, Ultrasound) and 6 weeks of routine knee exercises.

## Interventions

- **10 days of conventional physiotherapy (Hot Pack, TENS, Ultrasound) and 6 weeks of routine knee exercises** (OTHER) — For 10 days, conventional physical therapy consisting of Hot Pack, TENS, Ultrasound, and routine knee strengthening exercises was applied in the hospital. These knee exercises were continued for four weeks after the hospital treatment period.
- **Six weeks of core stabilization exercises.** (OTHER) — For six weeks, Warner et al. A core stabilization exercise protocol, as defined by was provided. This protocol included neutral spine position in hook position, activation of deep abdominal muscles, supine bridge, ipsilateral and contralateral limb movements in hook position, abdominal curl (sit-up), bridge (double and single leg), plank on knees, side plank on knees, clam exercise (without resistance), and modified 100 exercises. The exercises were performed 3 days a week, with 10 repetitions each.

## Primary Outcomes

- **Sit Ups** _(time frame: Baseline-6 weeks follow-up)_ — Participants are positioned supine with knees flexed and hands crossed over their shoulders. Their feet are held in place by the researcher, and the individual is asked to perform trunk flexion. The number of repetitions completed within 30 seconds is recorded.
- **Modified Push-Up** _(time frame: Baseline-6 weeks follow-up)_ — Participants lie face down on an exercise mat with their knees flexed. They are asked to lift their head, torso, and hips off the ground, placing their hands on the floor and extending their elbows, so that they form a straight line. The number of complete repetitions the participant performs while maintaining this straight line within 30 seconds is recorded.
- **Core Endurance Tests** _(time frame: Baseline-6 weeks follow-up)_ — Core endurance is determined by core endurance tests (right and left lateral bridge test, trunk extension test, trunk flexion test), as defined by McGgill, and the prone bridge test.

## Secondary Outcomes

- **30-Second Sit-Stand Test** _(time frame: Baseline-6 weeks follow-up)_
- **Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)** _(time frame: Baseline-6 weeks follow-up)_
- **Single Leg Balance Test** _(time frame: Baseline-6 weeks follow-up)_

## Locations (1)

- Sivas Cumhuriyet University, Sivas, Turkey (Türkiye) — _RECRUITING_

## Recent Field Changes (last 30 days)

- `status.overallStatus` — added _(2026-05-12)_
- `status.primaryCompletionDate` — added _(2026-05-12)_
- `status.completionDate` — added _(2026-05-12)_
- `status.lastUpdatePostDate` — added _(2026-05-12)_
- `design.phases` — added _(2026-05-12)_
- `design.enrollmentCount` — added _(2026-05-12)_
- `eligibility.criteria` — added _(2026-05-12)_
- `eligibility.minAge` — added _(2026-05-12)_
- `eligibility.maxAge` — added _(2026-05-12)_
- `eligibility.sex` — added _(2026-05-12)_
- `outcomes.primary` — added _(2026-05-12)_
- `outcomes.secondary` — added _(2026-05-12)_
- `armsInterventions.arms` — added _(2026-05-12)_
- `armsInterventions.interventions` — added _(2026-05-12)_
- `sponsor.lead` — added _(2026-05-12)_
- `results.hasResults` — added _(2026-05-12)_
- `locations.sivas cumhuriyet university|sivas||turkey (türkiye)` — added _(2026-05-12)_

---

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