# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 503 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated** — Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror** — A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Every public page has a clean Markdown twin at `<page-url>.md` with frontmatter, intended for LLM ingestion.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 503 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated — Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last? — HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last — Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials — HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials — Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials — HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know — HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo? — HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo — Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- How Close Is a Cure for Parkinson's Disease? — HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know — HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials — Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work? — HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work — Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis — HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis — Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says — HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk — Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials — HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials — Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care — HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons — Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md

## PD Curated — Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). The full set is in the sitemap; below are the 50 most recently updated for quick discovery.

- Virtual reality improves walking coordination (NCT07250672) — HTML: https://parkinsonspathways.com/trial/NCT07250672 — Markdown: https://parkinsonspathways.com/trial/NCT07250672.md
- Assess safety of gas medicine (NCT07005180) — HTML: https://parkinsonspathways.com/trial/NCT07005180 — Markdown: https://parkinsonspathways.com/trial/NCT07005180.md
- Sound waves reduce movement stiffness (NCT07207122) — HTML: https://parkinsonspathways.com/trial/NCT07207122 — Markdown: https://parkinsonspathways.com/trial/NCT07207122.md
- Reduce tremor and movement stiffness (NCT07572903) — HTML: https://parkinsonspathways.com/trial/NCT07572903 — Markdown: https://parkinsonspathways.com/trial/NCT07572903.md
- Reduce motor symptoms using neurofeedback (NCT06582355) — HTML: https://parkinsonspathways.com/trial/NCT06582355 — Markdown: https://parkinsonspathways.com/trial/NCT06582355.md
- Alleviate gait freezing and instability (NCT06295614) — HTML: https://parkinsonspathways.com/trial/NCT06295614 — Markdown: https://parkinsonspathways.com/trial/NCT06295614.md
- Detect Parkinson using gut biopsy (NCT05347407) — HTML: https://parkinsonspathways.com/trial/NCT05347407 — Markdown: https://parkinsonspathways.com/trial/NCT05347407.md
- Reduce pain and autonomic symptoms (NCT05748028) — HTML: https://parkinsonspathways.com/trial/NCT05748028 — Markdown: https://parkinsonspathways.com/trial/NCT05748028.md
- Improve walking balance and attention (NCT06444685) — HTML: https://parkinsonspathways.com/trial/NCT06444685 — Markdown: https://parkinsonspathways.com/trial/NCT06444685.md
- Track axial and cognitive progression (NCT07187843) — HTML: https://parkinsonspathways.com/trial/NCT07187843 — Markdown: https://parkinsonspathways.com/trial/NCT07187843.md
- Improve gait and balance remotely (NCT04720365) — HTML: https://parkinsonspathways.com/trial/NCT04720365 — Markdown: https://parkinsonspathways.com/trial/NCT04720365.md
- Improve walking and reduce stiffness (NCT07572071) — HTML: https://parkinsonspathways.com/trial/NCT07572071 — Markdown: https://parkinsonspathways.com/trial/NCT07572071.md
- Improve cognition through caudate stimulation (NCT04715984) — HTML: https://parkinsonspathways.com/trial/NCT04715984 — Markdown: https://parkinsonspathways.com/trial/NCT04715984.md
- Reduce freezing through brain stimulation (NCT06505460) — HTML: https://parkinsonspathways.com/trial/NCT06505460 — Markdown: https://parkinsonspathways.com/trial/NCT06505460.md
- Detect brain alpha synuclein deposits (NCT06891703) — HTML: https://parkinsonspathways.com/trial/NCT06891703 — Markdown: https://parkinsonspathways.com/trial/NCT06891703.md
- Reduce tremor through brain stimulation (NCT06013956) — HTML: https://parkinsonspathways.com/trial/NCT06013956 — Markdown: https://parkinsonspathways.com/trial/NCT06013956.md
- Use spinal fluid to diagnose (NCT04844060) — HTML: https://parkinsonspathways.com/trial/NCT04844060 — Markdown: https://parkinsonspathways.com/trial/NCT04844060.md
- Improve sleep in Parkinson patients (NCT05962489) — HTML: https://parkinsonspathways.com/trial/NCT05962489 — Markdown: https://parkinsonspathways.com/trial/NCT05962489.md
- Detect freezing through oculomotor markers (NCT06663826) — HTML: https://parkinsonspathways.com/trial/NCT06663826 — Markdown: https://parkinsonspathways.com/trial/NCT06663826.md
- Improve balance using exercise priming (NCT06133283) — HTML: https://parkinsonspathways.com/trial/NCT06133283 — Markdown: https://parkinsonspathways.com/trial/NCT06133283.md
- Test radotinib to slow progression (NCT04691661) — HTML: https://parkinsonspathways.com/trial/NCT04691661 — Markdown: https://parkinsonspathways.com/trial/NCT04691661.md
- Understand brain control of breathing (NCT06074614) — HTML: https://parkinsonspathways.com/trial/NCT06074614 — Markdown: https://parkinsonspathways.com/trial/NCT06074614.md
- Reduce constipation in Parkinson patients (NCT07310264) — HTML: https://parkinsonspathways.com/trial/NCT07310264 — Markdown: https://parkinsonspathways.com/trial/NCT07310264.md
- Improve walking using auditory cueing (NCT06142448) — HTML: https://parkinsonspathways.com/trial/NCT06142448 — Markdown: https://parkinsonspathways.com/trial/NCT06142448.md
- Identify neural causes of dysphagia (NCT07299448) — HTML: https://parkinsonspathways.com/trial/NCT07299448 — Markdown: https://parkinsonspathways.com/trial/NCT07299448.md
- Improve walking endurance and strength (NCT06893055) — HTML: https://parkinsonspathways.com/trial/NCT06893055 — Markdown: https://parkinsonspathways.com/trial/NCT06893055.md
- Test tenapanor for Parkinson constipation (NCT06460038) — HTML: https://parkinsonspathways.com/trial/NCT06460038 — Markdown: https://parkinsonspathways.com/trial/NCT06460038.md
- Reduce tremor and involuntary movements (NCT05626608) — HTML: https://parkinsonspathways.com/trial/NCT05626608 — Markdown: https://parkinsonspathways.com/trial/NCT05626608.md
- Improve upper limb motor learning (NCT07028515) — HTML: https://parkinsonspathways.com/trial/NCT07028515 — Markdown: https://parkinsonspathways.com/trial/NCT07028515.md
- Improve walking confidence through imagery (NCT07193355) — HTML: https://parkinsonspathways.com/trial/NCT07193355 — Markdown: https://parkinsonspathways.com/trial/NCT07193355.md
- Cycling slows Parkinson disease progression (NCT06442033) — HTML: https://parkinsonspathways.com/trial/NCT06442033 — Markdown: https://parkinsonspathways.com/trial/NCT06442033.md
- Improve mood through caudate stimulation (NCT07409207) — HTML: https://parkinsonspathways.com/trial/NCT07409207 — Markdown: https://parkinsonspathways.com/trial/NCT07409207.md
- Improve speech through perceptual learning (NCT07403539) — HTML: https://parkinsonspathways.com/trial/NCT07403539 — Markdown: https://parkinsonspathways.com/trial/NCT07403539.md
- Reduce freezing and improve walking (NCT06791902) — HTML: https://parkinsonspathways.com/trial/NCT06791902 — Markdown: https://parkinsonspathways.com/trial/NCT06791902.md
- Reduce falls by improving balance (NCT06598891) — HTML: https://parkinsonspathways.com/trial/NCT06598891 — Markdown: https://parkinsonspathways.com/trial/NCT06598891.md
- Improve hand dexterity with imagery (NCT07193303) — HTML: https://parkinsonspathways.com/trial/NCT07193303 — Markdown: https://parkinsonspathways.com/trial/NCT07193303.md
- Measure cognitive decline in Parkinsons (NCT04997642) — HTML: https://parkinsonspathways.com/trial/NCT04997642 — Markdown: https://parkinsonspathways.com/trial/NCT04997642.md
- Reduce tremor using Medtronic Activa (NCT01581580) — HTML: https://parkinsonspathways.com/trial/NCT01581580 — Markdown: https://parkinsonspathways.com/trial/NCT01581580.md
- Differentiate neurodegenerative diseases using saliva (NCT06869135) — HTML: https://parkinsonspathways.com/trial/NCT06869135 — Markdown: https://parkinsonspathways.com/trial/NCT06869135.md
- Slow Parkinson degeneration using Dserine (NCT07312110) — HTML: https://parkinsonspathways.com/trial/NCT07312110 — Markdown: https://parkinsonspathways.com/trial/NCT07312110.md
- Image brain alpha synuclein deposition (NCT07348250) — HTML: https://parkinsonspathways.com/trial/NCT07348250 — Markdown: https://parkinsonspathways.com/trial/NCT07348250.md
- Sensing brain stimulation lengthens sleep (NCT05070013) — HTML: https://parkinsonspathways.com/trial/NCT05070013 — Markdown: https://parkinsonspathways.com/trial/NCT05070013.md
- Smooth medication wearing off swings (NCT05916157) — HTML: https://parkinsonspathways.com/trial/NCT05916157 — Markdown: https://parkinsonspathways.com/trial/NCT05916157.md
- Reduce freezing episodes during walking (NCT06316232) — HTML: https://parkinsonspathways.com/trial/NCT06316232 — Markdown: https://parkinsonspathways.com/trial/NCT06316232.md
- Predict individual Parkinson disease progression (NCT05065060) — HTML: https://parkinsonspathways.com/trial/NCT05065060 — Markdown: https://parkinsonspathways.com/trial/NCT05065060.md
- Validate Turkish involuntary movements scale (NCT07023224) — HTML: https://parkinsonspathways.com/trial/NCT07023224 — Markdown: https://parkinsonspathways.com/trial/NCT07023224.md
- Measure dance exercise energy expenditure (NCT06425731) — HTML: https://parkinsonspathways.com/trial/NCT06425731 — Markdown: https://parkinsonspathways.com/trial/NCT06425731.md
- Reduce memory impairment using levetiracetam (NCT04643327) — HTML: https://parkinsonspathways.com/trial/NCT04643327 — Markdown: https://parkinsonspathways.com/trial/NCT04643327.md
- Improve balance using telerehabilitation games (NCT05773885) — HTML: https://parkinsonspathways.com/trial/NCT05773885 — Markdown: https://parkinsonspathways.com/trial/NCT05773885.md
- Reduce wearing off between doses (NCT07432958) — HTML: https://parkinsonspathways.com/trial/NCT07432958 — Markdown: https://parkinsonspathways.com/trial/NCT07432958.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only — no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml) — includes Learn and PD-trial Markdown twins
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml) — references the main sitemap plus paginated child sitemaps for every universal-mirror Markdown URL
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)