# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 502 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated** — Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror** — A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Selected content families expose clean Markdown twins (append `.md` to the URL) with YAML frontmatter, intended for LLM ingestion. Supported patterns: `/learn/{slug}.md`, `/trial/{nctId}.md`, `/trials-near-me.md`, `/trials-near-me/{city}.md`, `/trials/{type}/{slug}.md`, `/trials/eu/{euctId}.md`, `/trials/caution.md`. Pages such as `/`, `/about`, `/trials`, `/insights`, `/match`, and `/digest` do not have Markdown twins.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 502 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [Caution Hub](https://parkinsonspathways.com/trials/caution): How to spot a questionable clinical trial, plus the listings de-emphasized from the default browse for lacking standard safety safeguards.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated — Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last? — HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last — Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials — HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials — Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials — HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know — HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo? — HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo — Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- How Close Is a Cure for Parkinson's Disease? — HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know — HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials — Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work? — HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work — Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis — HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis — Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says — HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk — Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials — HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials — Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care — HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons — Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons — HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons — Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists — HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists — Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared — HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared — Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research — HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research — Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md
- tavapadon-new-parkinsons-drug-2026 — HTML: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026 — Markdown: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026.md
- state-of-parkinsons-clinical-trials — HTML: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials.md
- where-parkinsons-clinical-trials-happen — HTML: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen — Markdown: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen.md

## PD Curated — Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). Append `.md` to any `/trial/{nctId}` URL in the sitemap to reach its twin; below are the 50 most recently updated for quick discovery.

- New medication slows Parkinson progression (NCT07630545) — HTML: https://parkinsonspathways.com/trial/NCT07630545 — Markdown: https://parkinsonspathways.com/trial/NCT07630545.md
- Improve walking with remote touch (NCT07457710) — HTML: https://parkinsonspathways.com/trial/NCT07457710 — Markdown: https://parkinsonspathways.com/trial/NCT07457710.md
- Improve walking balance with neurofeedback (NCT05800470) — HTML: https://parkinsonspathways.com/trial/NCT05800470 — Markdown: https://parkinsonspathways.com/trial/NCT05800470.md
- Reduce exertion with adaptive stimulation (NCT06296810) — HTML: https://parkinsonspathways.com/trial/NCT06296810 — Markdown: https://parkinsonspathways.com/trial/NCT06296810.md
- Identify early striatal metabolite changes (NCT04735172) — HTML: https://parkinsonspathways.com/trial/NCT04735172 — Markdown: https://parkinsonspathways.com/trial/NCT04735172.md
- Diagnose Parkinsons disease with colonoscopy (NCT07204652) — HTML: https://parkinsonspathways.com/trial/NCT07204652 — Markdown: https://parkinsonspathways.com/trial/NCT07204652.md
- Distinguish essential tremor from Parkinsons (NCT06378619) — HTML: https://parkinsonspathways.com/trial/NCT06378619 — Markdown: https://parkinsonspathways.com/trial/NCT06378619.md
- Detect Parkinson and track severity (NCT07392411) — HTML: https://parkinsonspathways.com/trial/NCT07392411 — Markdown: https://parkinsonspathways.com/trial/NCT07392411.md
- Predict falls due to freezing (NCT07386015) — HTML: https://parkinsonspathways.com/trial/NCT07386015 — Markdown: https://parkinsonspathways.com/trial/NCT07386015.md
- Detect early Parkinson brain changes (NCT06449404) — HTML: https://parkinsonspathways.com/trial/NCT06449404 — Markdown: https://parkinsonspathways.com/trial/NCT06449404.md
- Help slow Parkinson disease progression (NCT04888364) — HTML: https://parkinsonspathways.com/trial/NCT04888364 — Markdown: https://parkinsonspathways.com/trial/NCT04888364.md
- Reduce tremor and movement stiffness (NCT07572903) — HTML: https://parkinsonspathways.com/trial/NCT07572903 — Markdown: https://parkinsonspathways.com/trial/NCT07572903.md
- Reduce camptocormia pain with stimulation (NCT06291051) — HTML: https://parkinsonspathways.com/trial/NCT06291051 — Markdown: https://parkinsonspathways.com/trial/NCT06291051.md
- Improve ability to stop actions (NCT07022522) — HTML: https://parkinsonspathways.com/trial/NCT07022522 — Markdown: https://parkinsonspathways.com/trial/NCT07022522.md
- Brain imaging maps protein clumps (NCT07020026) — HTML: https://parkinsonspathways.com/trial/NCT07020026 — Markdown: https://parkinsonspathways.com/trial/NCT07020026.md
- Reduce falls with treadmill training (NCT07058285) — HTML: https://parkinsonspathways.com/trial/NCT07058285 — Markdown: https://parkinsonspathways.com/trial/NCT07058285.md
- Reduce motor symptoms using synbiotic (NCT05576818) — HTML: https://parkinsonspathways.com/trial/NCT05576818 — Markdown: https://parkinsonspathways.com/trial/NCT05576818.md
- Improve walking endurance and strength (NCT06893055) — HTML: https://parkinsonspathways.com/trial/NCT06893055 — Markdown: https://parkinsonspathways.com/trial/NCT06893055.md
- Improve sleep with bright light (NCT06129942) — HTML: https://parkinsonspathways.com/trial/NCT06129942 — Markdown: https://parkinsonspathways.com/trial/NCT06129942.md
- Improve walking with mixed reality (NCT06459154) — HTML: https://parkinsonspathways.com/trial/NCT06459154 — Markdown: https://parkinsonspathways.com/trial/NCT06459154.md
- Stabilize movement reduce off periods (NCT06919822) — HTML: https://parkinsonspathways.com/trial/NCT06919822 — Markdown: https://parkinsonspathways.com/trial/NCT06919822.md
- Reduce freezing episodes during walking (NCT06316232) — HTML: https://parkinsonspathways.com/trial/NCT06316232 — Markdown: https://parkinsonspathways.com/trial/NCT06316232.md
- Reduce off time with infusion (NCT07382440) — HTML: https://parkinsonspathways.com/trial/NCT07382440 — Markdown: https://parkinsonspathways.com/trial/NCT07382440.md
- Reduce Parkinson fatigue through exercise (NCT06324422) — HTML: https://parkinsonspathways.com/trial/NCT06324422 — Markdown: https://parkinsonspathways.com/trial/NCT06324422.md
- Improve gait using Percept neurostimulation (NCT05820074) — HTML: https://parkinsonspathways.com/trial/NCT05820074 — Markdown: https://parkinsonspathways.com/trial/NCT05820074.md
- Improve arm dexterity with robotics (NCT06906679) — HTML: https://parkinsonspathways.com/trial/NCT06906679 — Markdown: https://parkinsonspathways.com/trial/NCT06906679.md
- Determine how balance affects sleep (NCT07424924) — HTML: https://parkinsonspathways.com/trial/NCT07424924 — Markdown: https://parkinsonspathways.com/trial/NCT07424924.md
- Increase daily steady on time (NCT07138560) — HTML: https://parkinsonspathways.com/trial/NCT07138560 — Markdown: https://parkinsonspathways.com/trial/NCT07138560.md
- Reduce tremor slowness and stiffness (NCT07348705) — HTML: https://parkinsonspathways.com/trial/NCT07348705 — Markdown: https://parkinsonspathways.com/trial/NCT07348705.md
- Numbing surgical area speeds recovery (NCT07176494) — HTML: https://parkinsonspathways.com/trial/NCT07176494 — Markdown: https://parkinsonspathways.com/trial/NCT07176494.md
- Find early tests for Parkinson (NCT06846658) — HTML: https://parkinsonspathways.com/trial/NCT06846658 — Markdown: https://parkinsonspathways.com/trial/NCT06846658.md
- Sound waves reduce movement stiffness (NCT07207122) — HTML: https://parkinsonspathways.com/trial/NCT07207122 — Markdown: https://parkinsonspathways.com/trial/NCT07207122.md
- Reduce tremor through brain stimulation (NCT06013956) — HTML: https://parkinsonspathways.com/trial/NCT06013956 — Markdown: https://parkinsonspathways.com/trial/NCT06013956.md
- Improve balance using wearable technology (NCT05680597) — HTML: https://parkinsonspathways.com/trial/NCT05680597 — Markdown: https://parkinsonspathways.com/trial/NCT05680597.md
- Silymarin slows Parkinson disease progression (NCT07001150) — HTML: https://parkinsonspathways.com/trial/NCT07001150 — Markdown: https://parkinsonspathways.com/trial/NCT07001150.md
- Reduce freezing episodes while walking (NCT07488026) — HTML: https://parkinsonspathways.com/trial/NCT07488026 — Markdown: https://parkinsonspathways.com/trial/NCT07488026.md
- Reduce motor symptoms with fasudil (NCT05931575) — HTML: https://parkinsonspathways.com/trial/NCT05931575 — Markdown: https://parkinsonspathways.com/trial/NCT05931575.md
- Improve movement with brain stimulation (NCT07524400) — HTML: https://parkinsonspathways.com/trial/NCT07524400 — Markdown: https://parkinsonspathways.com/trial/NCT07524400.md
- Reduce cognitive decline through exercise (NCT07324330) — HTML: https://parkinsonspathways.com/trial/NCT07324330 — Markdown: https://parkinsonspathways.com/trial/NCT07324330.md
- Reduce apathy through personalized music (NCT05505019) — HTML: https://parkinsonspathways.com/trial/NCT05505019 — Markdown: https://parkinsonspathways.com/trial/NCT05505019.md
- Driving simulator improves driving safety (NCT06320639) — HTML: https://parkinsonspathways.com/trial/NCT06320639 — Markdown: https://parkinsonspathways.com/trial/NCT06320639.md
- Detect early cognitive decline Parkinsons (NCT05025254) — HTML: https://parkinsonspathways.com/trial/NCT05025254 — Markdown: https://parkinsonspathways.com/trial/NCT05025254.md
- Link bacterial gene with constipation (NCT07175922) — HTML: https://parkinsonspathways.com/trial/NCT07175922 — Markdown: https://parkinsonspathways.com/trial/NCT07175922.md
- Improve everyday movement and thinking (NCT06879821) — HTML: https://parkinsonspathways.com/trial/NCT06879821 — Markdown: https://parkinsonspathways.com/trial/NCT06879821.md
- Reduce falls by improving balance (NCT06598891) — HTML: https://parkinsonspathways.com/trial/NCT06598891 — Markdown: https://parkinsonspathways.com/trial/NCT06598891.md
- Improve cognitive function with training (NCT06323278) — HTML: https://parkinsonspathways.com/trial/NCT06323278 — Markdown: https://parkinsonspathways.com/trial/NCT06323278.md
- Steadier brain pulses reduce tremor (NCT06742450) — HTML: https://parkinsonspathways.com/trial/NCT06742450 — Markdown: https://parkinsonspathways.com/trial/NCT06742450.md
- Improve walking balance and attention (NCT06444685) — HTML: https://parkinsonspathways.com/trial/NCT06444685 — Markdown: https://parkinsonspathways.com/trial/NCT06444685.md
- Retrain driving skills using simulator (NCT03969927) — HTML: https://parkinsonspathways.com/trial/NCT03969927 — Markdown: https://parkinsonspathways.com/trial/NCT03969927.md
- Identify genes influencing Parkinson progression (NCT06719583) — HTML: https://parkinsonspathways.com/trial/NCT06719583 — Markdown: https://parkinsonspathways.com/trial/NCT06719583.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only — no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml) — clean HTML URLs for every public page (only `/trial/{nctId}`, `/learn/{slug}`, `/trials-near-me`, `/trials-near-me/{city}`, `/trials/{type}/{slug}`, and `/trials/eu/{euctId}` entries support a `.md` twin)
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml) — references the main sitemap
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)