# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 506 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated** — Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror** — A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Selected content families expose clean Markdown twins (append `.md` to the URL) with YAML frontmatter, intended for LLM ingestion. Supported patterns: `/learn/{slug}.md`, `/trial/{nctId}.md`, `/trials-near-me.md`, `/trials-near-me/{city}.md`, `/trials/{type}/{slug}.md`, `/trials/eu/{euctId}.md`. Pages such as `/`, `/about`, `/trials`, `/insights`, `/match`, and `/digest` do not have Markdown twins.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 506 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated — Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last? — HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last — Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials — HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials — Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- How to Spot a Questionable Clinical Trial — HTML: https://parkinsonspathways.com/learn/how-to-spot-a-questionable-clinical-trial — Markdown: https://parkinsonspathways.com/learn/how-to-spot-a-questionable-clinical-trial.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials — HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know — HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo? — HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo — Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- How Close Is a Cure for Parkinson's Disease? — HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know — HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials — Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work? — HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work — Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis — HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis — Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says — HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk — Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials — HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials — Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care — HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons — Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons — HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons — Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists — HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists — Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared — HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared — Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research — HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research — Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md
- tavapadon-new-parkinsons-drug-2026 — HTML: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026 — Markdown: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026.md
- state-of-parkinsons-clinical-trials — HTML: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials.md
- where-parkinsons-clinical-trials-happen — HTML: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen — Markdown: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen.md

## PD Curated — Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). Append `.md` to any `/trial/{nctId}` URL in the sitemap to reach its twin; below are the 50 most recently updated for quick discovery.

- Improve side to side balance (NCT07568951) — HTML: https://parkinsonspathways.com/trial/NCT07568951 — Markdown: https://parkinsonspathways.com/trial/NCT07568951.md
- Improve balance with motor imagery (NCT06154356) — HTML: https://parkinsonspathways.com/trial/NCT06154356 — Markdown: https://parkinsonspathways.com/trial/NCT06154356.md
- Improve inspiratory strength and fitness (NCT07010783) — HTML: https://parkinsonspathways.com/trial/NCT07010783 — Markdown: https://parkinsonspathways.com/trial/NCT07010783.md
- Strengthen cough by forward flexion (NCT06955377) — HTML: https://parkinsonspathways.com/trial/NCT06955377 — Markdown: https://parkinsonspathways.com/trial/NCT06955377.md
- New medication slows Parkinson progression (NCT07630545) — HTML: https://parkinsonspathways.com/trial/NCT07630545 — Markdown: https://parkinsonspathways.com/trial/NCT07630545.md
- Test biophoton therapy for tremor (NCT06147999) — HTML: https://parkinsonspathways.com/trial/NCT06147999 — Markdown: https://parkinsonspathways.com/trial/NCT06147999.md
- Improve orthostatic blood pressure stability (NCT06920134) — HTML: https://parkinsonspathways.com/trial/NCT06920134 — Markdown: https://parkinsonspathways.com/trial/NCT06920134.md
- Ear stimulation reduces standing lightheadedness (NCT07557706) — HTML: https://parkinsonspathways.com/trial/NCT07557706 — Markdown: https://parkinsonspathways.com/trial/NCT07557706.md
- Slow Parkinson progression through lifestyle (NCT07443293) — HTML: https://parkinsonspathways.com/trial/NCT07443293 — Markdown: https://parkinsonspathways.com/trial/NCT07443293.md
- Distinguish Parkinson from similar disorders (NCT07392411) — HTML: https://parkinsonspathways.com/trial/NCT07392411 — Markdown: https://parkinsonspathways.com/trial/NCT07392411.md
- Reduce overactive dopamine related behaviors (NCT07151378) — HTML: https://parkinsonspathways.com/trial/NCT07151378 — Markdown: https://parkinsonspathways.com/trial/NCT07151378.md
- Map movement mood and sleep (NCT06536348) — HTML: https://parkinsonspathways.com/trial/NCT06536348 — Markdown: https://parkinsonspathways.com/trial/NCT06536348.md
- Reduce tremor and movement stiffness (NCT07572903) — HTML: https://parkinsonspathways.com/trial/NCT07572903 — Markdown: https://parkinsonspathways.com/trial/NCT07572903.md
- Slow Parkinson degeneration using Dserine (NCT07312110) — HTML: https://parkinsonspathways.com/trial/NCT07312110 — Markdown: https://parkinsonspathways.com/trial/NCT07312110.md
- Aerobic exercise slows Parkinson progression (NCT05854524) — HTML: https://parkinsonspathways.com/trial/NCT05854524 — Markdown: https://parkinsonspathways.com/trial/NCT05854524.md
- Reduce tremor and involuntary movements (NCT05626608) — HTML: https://parkinsonspathways.com/trial/NCT05626608 — Markdown: https://parkinsonspathways.com/trial/NCT05626608.md
- Confirm tremor control under anesthesia (NCT05550714) — HTML: https://parkinsonspathways.com/trial/NCT05550714 — Markdown: https://parkinsonspathways.com/trial/NCT05550714.md
- Improve walking speed and stability (NCT07105787) — HTML: https://parkinsonspathways.com/trial/NCT07105787 — Markdown: https://parkinsonspathways.com/trial/NCT07105787.md
- Brain stimulation helps thinking problems (NCT06399731) — HTML: https://parkinsonspathways.com/trial/NCT06399731 — Markdown: https://parkinsonspathways.com/trial/NCT06399731.md
- Improve obstacle crossing while walking (NCT06932679) — HTML: https://parkinsonspathways.com/trial/NCT06932679 — Markdown: https://parkinsonspathways.com/trial/NCT06932679.md
- Detect walking and balance problems (NCT07281794) — HTML: https://parkinsonspathways.com/trial/NCT07281794 — Markdown: https://parkinsonspathways.com/trial/NCT07281794.md
- Reduce daily off medication time (NCT06944522) — HTML: https://parkinsonspathways.com/trial/NCT06944522 — Markdown: https://parkinsonspathways.com/trial/NCT06944522.md
- Home brain stimulation improves walking (NCT07518290) — HTML: https://parkinsonspathways.com/trial/NCT07518290 — Markdown: https://parkinsonspathways.com/trial/NCT07518290.md
- Improve arm dexterity with robotics (NCT06906679) — HTML: https://parkinsonspathways.com/trial/NCT06906679 — Markdown: https://parkinsonspathways.com/trial/NCT06906679.md
- Reduce early Parkinsons motor symptoms (NCT06874803) — HTML: https://parkinsonspathways.com/trial/NCT06874803 — Markdown: https://parkinsonspathways.com/trial/NCT06874803.md
- Identify signals predicting mood fluctuations (NCT07404241) — HTML: https://parkinsonspathways.com/trial/NCT07404241 — Markdown: https://parkinsonspathways.com/trial/NCT07404241.md
- Reduce freezing during walking remotely (NCT06957405) — HTML: https://parkinsonspathways.com/trial/NCT06957405 — Markdown: https://parkinsonspathways.com/trial/NCT06957405.md
- Improve walking with red light (NCT06916260) — HTML: https://parkinsonspathways.com/trial/NCT06916260 — Markdown: https://parkinsonspathways.com/trial/NCT06916260.md
- Ear stimulation slows Parkinson progression (NCT06665113) — HTML: https://parkinsonspathways.com/trial/NCT06665113 — Markdown: https://parkinsonspathways.com/trial/NCT06665113.md
- Identify inherited genes causing Parkinson (NCT01558479) — HTML: https://parkinsonspathways.com/trial/NCT01558479 — Markdown: https://parkinsonspathways.com/trial/NCT01558479.md
- Find safe gene therapy dose (NCT07371338) — HTML: https://parkinsonspathways.com/trial/NCT07371338 — Markdown: https://parkinsonspathways.com/trial/NCT07371338.md
- Test febuxostat and inosine neuroprotection (NCT07170475) — HTML: https://parkinsonspathways.com/trial/NCT07170475 — Markdown: https://parkinsonspathways.com/trial/NCT07170475.md
- Sustain tremor improvement after stimulation (NCT06570421) — HTML: https://parkinsonspathways.com/trial/NCT06570421 — Markdown: https://parkinsonspathways.com/trial/NCT06570421.md
- Guide brain stimulation contact selection (NCT07485621) — HTML: https://parkinsonspathways.com/trial/NCT07485621 — Markdown: https://parkinsonspathways.com/trial/NCT07485621.md
- Cell transplant improves movement symptoms (NCT07572071) — HTML: https://parkinsonspathways.com/trial/NCT07572071 — Markdown: https://parkinsonspathways.com/trial/NCT07572071.md
- Identify cognitive decline in Parkinsons (NCT03402919) — HTML: https://parkinsonspathways.com/trial/NCT03402919 — Markdown: https://parkinsonspathways.com/trial/NCT03402919.md
- Collaborative virtual reality improves walking (NCT07523425) — HTML: https://parkinsonspathways.com/trial/NCT07523425 — Markdown: https://parkinsonspathways.com/trial/NCT07523425.md
- Improve upper limb motor learning (NCT07028515) — HTML: https://parkinsonspathways.com/trial/NCT07028515 — Markdown: https://parkinsonspathways.com/trial/NCT07028515.md
- Reduce depressive symptoms using ketamine (NCT06231563) — HTML: https://parkinsonspathways.com/trial/NCT06231563 — Markdown: https://parkinsonspathways.com/trial/NCT06231563.md
- Reduce hallucinations without worsening movement (NCT04373317) — HTML: https://parkinsonspathways.com/trial/NCT04373317 — Markdown: https://parkinsonspathways.com/trial/NCT04373317.md
- Improve movement with ear stimulation (NCT06409338) — HTML: https://parkinsonspathways.com/trial/NCT06409338 — Markdown: https://parkinsonspathways.com/trial/NCT06409338.md
- Reduce movement and nonmotor symptoms (NCT07625540) — HTML: https://parkinsonspathways.com/trial/NCT07625540 — Markdown: https://parkinsonspathways.com/trial/NCT07625540.md
- Speech tracks movement mood thinking (NCT05765110) — HTML: https://parkinsonspathways.com/trial/NCT05765110 — Markdown: https://parkinsonspathways.com/trial/NCT05765110.md
- Vibrating shoe improves walking stability (NCT06975059) — HTML: https://parkinsonspathways.com/trial/NCT06975059 — Markdown: https://parkinsonspathways.com/trial/NCT06975059.md
- Personalized brain stimulation improves walking (NCT06350617) — HTML: https://parkinsonspathways.com/trial/NCT06350617 — Markdown: https://parkinsonspathways.com/trial/NCT06350617.md
- Determine whether immunosuppression slows progression (NCT06834191) — HTML: https://parkinsonspathways.com/trial/NCT06834191 — Markdown: https://parkinsonspathways.com/trial/NCT06834191.md
- Relieve movement symptoms between doses (NCT07400731) — HTML: https://parkinsonspathways.com/trial/NCT07400731 — Markdown: https://parkinsonspathways.com/trial/NCT07400731.md
- Improve motor symptoms via glucose (NCT05998772) — HTML: https://parkinsonspathways.com/trial/NCT05998772 — Markdown: https://parkinsonspathways.com/trial/NCT05998772.md
- Validate wearable assessment of walking (NCT05874739) — HTML: https://parkinsonspathways.com/trial/NCT05874739 — Markdown: https://parkinsonspathways.com/trial/NCT05874739.md
- Increase walking distance and endurance (NCT06859528) — HTML: https://parkinsonspathways.com/trial/NCT06859528 — Markdown: https://parkinsonspathways.com/trial/NCT06859528.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only — no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml) — clean HTML URLs for every public page (only `/trial/{nctId}`, `/learn/{slug}`, `/trials-near-me`, `/trials-near-me/{city}`, `/trials/{type}/{slug}`, and `/trials/eu/{euctId}` entries support a `.md` twin)
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml) — references the main sitemap
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)