# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 507 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated** — Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror** — A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Every public page has a clean Markdown twin at `<page-url>.md` with frontmatter, intended for LLM ingestion.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 507 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated — Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last? — HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last — Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials — HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials — Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials — HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know — HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo? — HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo — Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- How Close Is a Cure for Parkinson's Disease? — HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know — HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials — Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work? — HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work — Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis — HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis — Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says — HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk — Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials — HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials — Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care — HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons — Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons — HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons — Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists — HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists — Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared — HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared — Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research — HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research — Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md

## PD Curated — Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). The full set is in the sitemap; below are the 50 most recently updated for quick discovery.

- Brain stimulation changes breathing function (NCT04058457) — HTML: https://parkinsonspathways.com/trial/NCT04058457 — Markdown: https://parkinsonspathways.com/trial/NCT04058457.md
- Improve cognitive function in Parkinsons (NCT03836950) — HTML: https://parkinsonspathways.com/trial/NCT03836950 — Markdown: https://parkinsonspathways.com/trial/NCT03836950.md
- Detect brain alpha synuclein deposits (NCT06891703) — HTML: https://parkinsonspathways.com/trial/NCT06891703 — Markdown: https://parkinsonspathways.com/trial/NCT06891703.md
- Reduce slowness stiffness and tremor (NCT05268887) — HTML: https://parkinsonspathways.com/trial/NCT05268887 — Markdown: https://parkinsonspathways.com/trial/NCT05268887.md
- Individualized brain stimulation improves walking (NCT07570212) — HTML: https://parkinsonspathways.com/trial/NCT07570212 — Markdown: https://parkinsonspathways.com/trial/NCT07570212.md
- Improve balance through mental rehearsal (NCT07495462) — HTML: https://parkinsonspathways.com/trial/NCT07495462 — Markdown: https://parkinsonspathways.com/trial/NCT07495462.md
- Improve thinking with brain stimulation (NCT06090682) — HTML: https://parkinsonspathways.com/trial/NCT06090682 — Markdown: https://parkinsonspathways.com/trial/NCT06090682.md
- Improve walking using resistance training (NCT07378813) — HTML: https://parkinsonspathways.com/trial/NCT07378813 — Markdown: https://parkinsonspathways.com/trial/NCT07378813.md
- Reduce freezing episodes during walking (NCT06982638) — HTML: https://parkinsonspathways.com/trial/NCT06982638 — Markdown: https://parkinsonspathways.com/trial/NCT06982638.md
- Improve walking balance via aquatherapy (NCT07390825) — HTML: https://parkinsonspathways.com/trial/NCT07390825 — Markdown: https://parkinsonspathways.com/trial/NCT07390825.md
- Reduce freezing episodes during walking (NCT06911229) — HTML: https://parkinsonspathways.com/trial/NCT06911229 — Markdown: https://parkinsonspathways.com/trial/NCT06911229.md
- Improve gait balance and attention (NCT07465107) — HTML: https://parkinsonspathways.com/trial/NCT07465107 — Markdown: https://parkinsonspathways.com/trial/NCT07465107.md
- Reduce cognitive decline through exercise (NCT07324330) — HTML: https://parkinsonspathways.com/trial/NCT07324330 — Markdown: https://parkinsonspathways.com/trial/NCT07324330.md
- Predict falls by assessing balance (NCT07148700) — HTML: https://parkinsonspathways.com/trial/NCT07148700 — Markdown: https://parkinsonspathways.com/trial/NCT07148700.md
- Validate wearable assessment of walking (NCT05874739) — HTML: https://parkinsonspathways.com/trial/NCT05874739 — Markdown: https://parkinsonspathways.com/trial/NCT05874739.md
- Steady medication infusion improves sleep (NCT07284342) — HTML: https://parkinsonspathways.com/trial/NCT07284342 — Markdown: https://parkinsonspathways.com/trial/NCT07284342.md
- Reduce daily off medication time (NCT06944522) — HTML: https://parkinsonspathways.com/trial/NCT06944522 — Markdown: https://parkinsonspathways.com/trial/NCT06944522.md
- Lemborexant improves motor and sleep (NCT07384429) — HTML: https://parkinsonspathways.com/trial/NCT07384429 — Markdown: https://parkinsonspathways.com/trial/NCT07384429.md
- Detect early loss of dopamine (NCT06456684) — HTML: https://parkinsonspathways.com/trial/NCT06456684 — Markdown: https://parkinsonspathways.com/trial/NCT06456684.md
- Track disease progression in Parkinson (NCT07353463) — HTML: https://parkinsonspathways.com/trial/NCT07353463 — Markdown: https://parkinsonspathways.com/trial/NCT07353463.md
- Replace lost dopamine producing neurons (NCT06608355) — HTML: https://parkinsonspathways.com/trial/NCT06608355 — Markdown: https://parkinsonspathways.com/trial/NCT06608355.md
- Improve cognition and motor function (NCT05307055) — HTML: https://parkinsonspathways.com/trial/NCT05307055 — Markdown: https://parkinsonspathways.com/trial/NCT05307055.md
- Improve balance through virtual reality (NCT07359716) — HTML: https://parkinsonspathways.com/trial/NCT07359716 — Markdown: https://parkinsonspathways.com/trial/NCT07359716.md
- Image abnormal brain protein deposits (NCT06303921) — HTML: https://parkinsonspathways.com/trial/NCT06303921 — Markdown: https://parkinsonspathways.com/trial/NCT06303921.md
- Steadier brain pulses reduce tremor (NCT06742450) — HTML: https://parkinsonspathways.com/trial/NCT06742450 — Markdown: https://parkinsonspathways.com/trial/NCT06742450.md
- Improve gait stability using cane (NCT06950255) — HTML: https://parkinsonspathways.com/trial/NCT06950255 — Markdown: https://parkinsonspathways.com/trial/NCT06950255.md
- Improve walking with robotic treadmill (NCT04087031) — HTML: https://parkinsonspathways.com/trial/NCT04087031 — Markdown: https://parkinsonspathways.com/trial/NCT04087031.md
- Improve everyday walking after training (NCT07351032) — HTML: https://parkinsonspathways.com/trial/NCT07351032 — Markdown: https://parkinsonspathways.com/trial/NCT07351032.md
- Identify markers predicting Parkinson progression (NCT02305147) — HTML: https://parkinsonspathways.com/trial/NCT02305147 — Markdown: https://parkinsonspathways.com/trial/NCT02305147.md
- Improve mobility through physical activity (NCT06901869) — HTML: https://parkinsonspathways.com/trial/NCT06901869 — Markdown: https://parkinsonspathways.com/trial/NCT06901869.md
- Improve targeting for brain stimulation (NCT00575081) — HTML: https://parkinsonspathways.com/trial/NCT00575081 — Markdown: https://parkinsonspathways.com/trial/NCT00575081.md
- Brain stimulation reduces disabling tremor (NCT02119611) — HTML: https://parkinsonspathways.com/trial/NCT02119611 — Markdown: https://parkinsonspathways.com/trial/NCT02119611.md
- Identify candidates for gene therapy (NCT06151002) — HTML: https://parkinsonspathways.com/trial/NCT06151002 — Markdown: https://parkinsonspathways.com/trial/NCT06151002.md
- Improve gait and balance remotely (NCT04720365) — HTML: https://parkinsonspathways.com/trial/NCT04720365 — Markdown: https://parkinsonspathways.com/trial/NCT04720365.md
- Brain stimulation improves stopping movements (NCT04061135) — HTML: https://parkinsonspathways.com/trial/NCT04061135 — Markdown: https://parkinsonspathways.com/trial/NCT04061135.md
- Improve cognitive function with training (NCT06323278) — HTML: https://parkinsonspathways.com/trial/NCT06323278 — Markdown: https://parkinsonspathways.com/trial/NCT06323278.md
- Improve movement via sensory filtering (NCT05482126) — HTML: https://parkinsonspathways.com/trial/NCT05482126 — Markdown: https://parkinsonspathways.com/trial/NCT05482126.md
- Improve gait using Percept neurostimulation (NCT05820074) — HTML: https://parkinsonspathways.com/trial/NCT05820074 — Markdown: https://parkinsonspathways.com/trial/NCT05820074.md
- Reduce freezing episodes while walking (NCT06506058) — HTML: https://parkinsonspathways.com/trial/NCT06506058 — Markdown: https://parkinsonspathways.com/trial/NCT06506058.md
- Reduce medication resistant motor symptoms (NCT07371338) — HTML: https://parkinsonspathways.com/trial/NCT07371338 — Markdown: https://parkinsonspathways.com/trial/NCT07371338.md
- Improve language processing and behavior (NCT07449117) — HTML: https://parkinsonspathways.com/trial/NCT07449117 — Markdown: https://parkinsonspathways.com/trial/NCT07449117.md
- Test drug safety in Parkinson (NCT06466525) — HTML: https://parkinsonspathways.com/trial/NCT06466525 — Markdown: https://parkinsonspathways.com/trial/NCT06466525.md
- Link bacterial gene with constipation (NCT07175922) — HTML: https://parkinsonspathways.com/trial/NCT07175922 — Markdown: https://parkinsonspathways.com/trial/NCT07175922.md
- Help decide about brain stimulation (NCT06446505) — HTML: https://parkinsonspathways.com/trial/NCT06446505 — Markdown: https://parkinsonspathways.com/trial/NCT06446505.md
- Reduce freezing with dynamic cycling (NCT05298150) — HTML: https://parkinsonspathways.com/trial/NCT05298150 — Markdown: https://parkinsonspathways.com/trial/NCT05298150.md
- Restore dopamine to improve walking (NCT05901818) — HTML: https://parkinsonspathways.com/trial/NCT05901818 — Markdown: https://parkinsonspathways.com/trial/NCT05901818.md
- Characterize freezing of gait episodes (NCT06519279) — HTML: https://parkinsonspathways.com/trial/NCT06519279 — Markdown: https://parkinsonspathways.com/trial/NCT06519279.md
- Reduce motor symptoms using synbiotic (NCT05576818) — HTML: https://parkinsonspathways.com/trial/NCT05576818 — Markdown: https://parkinsonspathways.com/trial/NCT05576818.md
- Steady infusion reduces off periods (NCT06937034) — HTML: https://parkinsonspathways.com/trial/NCT06937034 — Markdown: https://parkinsonspathways.com/trial/NCT06937034.md
- Correlate synaptic loss with cognition (NCT06875765) — HTML: https://parkinsonspathways.com/trial/NCT06875765 — Markdown: https://parkinsonspathways.com/trial/NCT06875765.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only — no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml) — includes Learn and PD-trial Markdown twins
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml) — references the main sitemap plus paginated child sitemaps for every universal-mirror Markdown URL
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)