# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 502 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated** — Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror** — A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Every public page has a clean Markdown twin at `<page-url>.md` with frontmatter, intended for LLM ingestion.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 502 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated — Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last? — HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last — Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials — HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials — Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials — HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know — HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo? — HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo — Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- How Close Is a Cure for Parkinson's Disease? — HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know — HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials — Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work? — HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work — Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis — HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis — Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says — HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk — Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials — HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials — Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care — HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons — Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons — HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons — Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists — HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists — Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared — HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared — Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research — HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research — Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md
- tavapadon-new-parkinsons-drug-2026 — HTML: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026 — Markdown: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026.md
- state-of-parkinsons-clinical-trials — HTML: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials.md
- where-parkinsons-clinical-trials-happen — HTML: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen — Markdown: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen.md

## PD Curated — Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). Append `.md` to any `/trial/{nctId}` URL in the sitemap to reach its twin; below are the 50 most recently updated for quick discovery.

- Predict falls by assessing balance (NCT07148700) — HTML: https://parkinsonspathways.com/trial/NCT07148700 — Markdown: https://parkinsonspathways.com/trial/NCT07148700.md
- Improve mood through caudate stimulation (NCT07409207) — HTML: https://parkinsonspathways.com/trial/NCT07409207 — Markdown: https://parkinsonspathways.com/trial/NCT07409207.md
- Predict brain stimulation easing freezing (NCT06951906) — HTML: https://parkinsonspathways.com/trial/NCT06951906 — Markdown: https://parkinsonspathways.com/trial/NCT06951906.md
- Alleviate gait freezing and instability (NCT06295614) — HTML: https://parkinsonspathways.com/trial/NCT06295614 — Markdown: https://parkinsonspathways.com/trial/NCT06295614.md
- Understand brain control of breathing (NCT06074614) — HTML: https://parkinsonspathways.com/trial/NCT06074614 — Markdown: https://parkinsonspathways.com/trial/NCT06074614.md
- Restore dopamine production in putamen (NCT07106021) — HTML: https://parkinsonspathways.com/trial/NCT07106021 — Markdown: https://parkinsonspathways.com/trial/NCT07106021.md
- Improve gait balance and speech (NCT05402163) — HTML: https://parkinsonspathways.com/trial/NCT05402163 — Markdown: https://parkinsonspathways.com/trial/NCT05402163.md
- Reduce freezing with dynamic cycling (NCT05298150) — HTML: https://parkinsonspathways.com/trial/NCT05298150 — Markdown: https://parkinsonspathways.com/trial/NCT05298150.md
- Probiotic cocktail delays Parkinson progression (NCT07619560) — HTML: https://parkinsonspathways.com/trial/NCT07619560 — Markdown: https://parkinsonspathways.com/trial/NCT07619560.md
- Predict treatment response from genetics (NCT03523052) — HTML: https://parkinsonspathways.com/trial/NCT03523052 — Markdown: https://parkinsonspathways.com/trial/NCT03523052.md
- Personalized stimulation to improve walking (NCT06350617) — HTML: https://parkinsonspathways.com/trial/NCT06350617 — Markdown: https://parkinsonspathways.com/trial/NCT06350617.md
- Brain imaging maps protein clumps (NCT07020026) — HTML: https://parkinsonspathways.com/trial/NCT07020026 — Markdown: https://parkinsonspathways.com/trial/NCT07020026.md
- Exoskeleton improves balance while walking (NCT07567482) — HTML: https://parkinsonspathways.com/trial/NCT07567482 — Markdown: https://parkinsonspathways.com/trial/NCT07567482.md
- Improve walking speed with vibrotactile (NCT07308418) — HTML: https://parkinsonspathways.com/trial/NCT07308418 — Markdown: https://parkinsonspathways.com/trial/NCT07308418.md
- Assess safety of gas medicine (NCT07005180) — HTML: https://parkinsonspathways.com/trial/NCT07005180 — Markdown: https://parkinsonspathways.com/trial/NCT07005180.md
- Reduce exertion with adaptive stimulation (NCT06296810) — HTML: https://parkinsonspathways.com/trial/NCT06296810 — Markdown: https://parkinsonspathways.com/trial/NCT06296810.md
- Estimate Parkinson risk after pesticides (NCT06420310) — HTML: https://parkinsonspathways.com/trial/NCT06420310 — Markdown: https://parkinsonspathways.com/trial/NCT06420310.md
- Detect early Parkinson via blood (NCT05385315) — HTML: https://parkinsonspathways.com/trial/NCT05385315 — Markdown: https://parkinsonspathways.com/trial/NCT05385315.md
- Gentle ear stimulation improves movement (NCT06409338) — HTML: https://parkinsonspathways.com/trial/NCT06409338 — Markdown: https://parkinsonspathways.com/trial/NCT06409338.md
- Improve speech clarity and walking (NCT07588191) — HTML: https://parkinsonspathways.com/trial/NCT07588191 — Markdown: https://parkinsonspathways.com/trial/NCT07588191.md
- Steadier brain pulses reduce tremor (NCT06742450) — HTML: https://parkinsonspathways.com/trial/NCT06742450 — Markdown: https://parkinsonspathways.com/trial/NCT06742450.md
- Hippotherapy improves balance and mobility (NCT06500182) — HTML: https://parkinsonspathways.com/trial/NCT06500182 — Markdown: https://parkinsonspathways.com/trial/NCT06500182.md
- Measure cognitive decline in Parkinsons (NCT04997642) — HTML: https://parkinsonspathways.com/trial/NCT04997642 — Markdown: https://parkinsonspathways.com/trial/NCT04997642.md
- Tenofovir slows Parkinson disease progression (NCT06356662) — HTML: https://parkinsonspathways.com/trial/NCT06356662 — Markdown: https://parkinsonspathways.com/trial/NCT06356662.md
- Reduce hallucinations without worsening movement (NCT05824728) — HTML: https://parkinsonspathways.com/trial/NCT05824728 — Markdown: https://parkinsonspathways.com/trial/NCT05824728.md
- Reduce tremor slowness and stiffness (NCT04681534) — HTML: https://parkinsonspathways.com/trial/NCT04681534 — Markdown: https://parkinsonspathways.com/trial/NCT04681534.md
- Optimize electrode placement using esketamine (NCT06543563) — HTML: https://parkinsonspathways.com/trial/NCT06543563 — Markdown: https://parkinsonspathways.com/trial/NCT06543563.md
- Improve walking speed and balance (NCT07381907) — HTML: https://parkinsonspathways.com/trial/NCT07381907 — Markdown: https://parkinsonspathways.com/trial/NCT07381907.md
- Improve obstacle crossing while walking (NCT06932679) — HTML: https://parkinsonspathways.com/trial/NCT06932679 — Markdown: https://parkinsonspathways.com/trial/NCT06932679.md
- Reduce freezing episodes while walking (NCT06848205) — HTML: https://parkinsonspathways.com/trial/NCT06848205 — Markdown: https://parkinsonspathways.com/trial/NCT06848205.md
- Predict falls due to freezing (NCT07386015) — HTML: https://parkinsonspathways.com/trial/NCT07386015 — Markdown: https://parkinsonspathways.com/trial/NCT07386015.md
- Reduce freezing episodes during walking (NCT06316232) — HTML: https://parkinsonspathways.com/trial/NCT06316232 — Markdown: https://parkinsonspathways.com/trial/NCT06316232.md
- Replace lost dopamine producing neurons (NCT06167681) — HTML: https://parkinsonspathways.com/trial/NCT06167681 — Markdown: https://parkinsonspathways.com/trial/NCT06167681.md
- Detect Parkinson using gut biopsy (NCT05347407) — HTML: https://parkinsonspathways.com/trial/NCT05347407 — Markdown: https://parkinsonspathways.com/trial/NCT05347407.md
- Test new antibody slows progression (NCT06809400) — HTML: https://parkinsonspathways.com/trial/NCT06809400 — Markdown: https://parkinsonspathways.com/trial/NCT06809400.md
- Magnetic stimulation slows Parkinson progression (NCT06002581) — HTML: https://parkinsonspathways.com/trial/NCT06002581 — Markdown: https://parkinsonspathways.com/trial/NCT06002581.md
- Improve cognitive function with tributyrin (NCT07154511) — HTML: https://parkinsonspathways.com/trial/NCT07154511 — Markdown: https://parkinsonspathways.com/trial/NCT07154511.md
- Improve walking mobility using exoskeleton (NCT06028529) — HTML: https://parkinsonspathways.com/trial/NCT06028529 — Markdown: https://parkinsonspathways.com/trial/NCT06028529.md
- Improve arm dexterity with robotics (NCT06906679) — HTML: https://parkinsonspathways.com/trial/NCT06906679 — Markdown: https://parkinsonspathways.com/trial/NCT06906679.md
- Brain stimulation improves stopping movements (NCT04061135) — HTML: https://parkinsonspathways.com/trial/NCT04061135 — Markdown: https://parkinsonspathways.com/trial/NCT04061135.md
- Create personalized stem cell therapies (NCT00874783) — HTML: https://parkinsonspathways.com/trial/NCT00874783 — Markdown: https://parkinsonspathways.com/trial/NCT00874783.md
- Reduce medication wearing off symptoms (NCT06145711) — HTML: https://parkinsonspathways.com/trial/NCT06145711 — Markdown: https://parkinsonspathways.com/trial/NCT06145711.md
- Improve gait balance and attention (NCT07465107) — HTML: https://parkinsonspathways.com/trial/NCT07465107 — Markdown: https://parkinsonspathways.com/trial/NCT07465107.md
- Improve balance through virtual reality (NCT07359716) — HTML: https://parkinsonspathways.com/trial/NCT07359716 — Markdown: https://parkinsonspathways.com/trial/NCT07359716.md
- Gene therapy improves motor control (NCT07100171) — HTML: https://parkinsonspathways.com/trial/NCT07100171 — Markdown: https://parkinsonspathways.com/trial/NCT07100171.md
- Reduce slowness stiffness and tremor (NCT05268887) — HTML: https://parkinsonspathways.com/trial/NCT05268887 — Markdown: https://parkinsonspathways.com/trial/NCT05268887.md
- Reduce lower extremity muscle stiffness (NCT05884944) — HTML: https://parkinsonspathways.com/trial/NCT05884944 — Markdown: https://parkinsonspathways.com/trial/NCT05884944.md
- Prevent mania after brain stimulation (NCT05444907) — HTML: https://parkinsonspathways.com/trial/NCT05444907 — Markdown: https://parkinsonspathways.com/trial/NCT05444907.md
- Improve constipation with fecal transplant (NCT06388863) — HTML: https://parkinsonspathways.com/trial/NCT06388863 — Markdown: https://parkinsonspathways.com/trial/NCT06388863.md
- Identify cognitive decline in Parkinsons (NCT03402919) — HTML: https://parkinsonspathways.com/trial/NCT03402919 — Markdown: https://parkinsonspathways.com/trial/NCT03402919.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only — no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml) — clean HTML URLs for every public page (append `.md` to any entry to reach its Markdown twin)
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml) — references the main sitemap
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)