# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 507 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated** — Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror** — A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Every public page has a clean Markdown twin at `<page-url>.md` with frontmatter, intended for LLM ingestion.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 507 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated — Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last? — HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last — Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials — HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials — Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials — HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know — HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo? — HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo — Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- How Close Is a Cure for Parkinson's Disease? — HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know — HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials — Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work? — HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work — Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis — HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis — Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says — HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk — Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials — HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials — Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care — HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons — Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons — HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons — Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists — HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists — Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared — HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared — Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research — HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research — Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md
- tavapadon-new-parkinsons-drug-2026 — HTML: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026 — Markdown: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026.md

## PD Curated — Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). The full set is in the sitemap; below are the 50 most recently updated for quick discovery.

- Reduce depressive symptoms using ketamine (NCT06231563) — HTML: https://parkinsonspathways.com/trial/NCT06231563 — Markdown: https://parkinsonspathways.com/trial/NCT06231563.md
- Treat Parkinson depression with probiotics (NCT05568498) — HTML: https://parkinsonspathways.com/trial/NCT05568498 — Markdown: https://parkinsonspathways.com/trial/NCT05568498.md
- Improve insomnia with pallidal stimulation (NCT04116996) — HTML: https://parkinsonspathways.com/trial/NCT04116996 — Markdown: https://parkinsonspathways.com/trial/NCT04116996.md
- Validate scales measuring mood fluctuations (NCT04366804) — HTML: https://parkinsonspathways.com/trial/NCT04366804 — Markdown: https://parkinsonspathways.com/trial/NCT04366804.md
- Improve balance through virtual reality (NCT07359716) — HTML: https://parkinsonspathways.com/trial/NCT07359716 — Markdown: https://parkinsonspathways.com/trial/NCT07359716.md
- Hippotherapy improves balance and mobility (NCT06500182) — HTML: https://parkinsonspathways.com/trial/NCT06500182 — Markdown: https://parkinsonspathways.com/trial/NCT06500182.md
- Reduce falls by improving balance (NCT06508801) — HTML: https://parkinsonspathways.com/trial/NCT06508801 — Markdown: https://parkinsonspathways.com/trial/NCT06508801.md
- Link hormones with motor fluctuations (NCT06582212) — HTML: https://parkinsonspathways.com/trial/NCT06582212 — Markdown: https://parkinsonspathways.com/trial/NCT06582212.md
- Improve walking speed and stability (NCT07105787) — HTML: https://parkinsonspathways.com/trial/NCT07105787 — Markdown: https://parkinsonspathways.com/trial/NCT07105787.md
- Improve walking through transcranial stimulation (NCT07182058) — HTML: https://parkinsonspathways.com/trial/NCT07182058 — Markdown: https://parkinsonspathways.com/trial/NCT07182058.md
- Improve hand dexterity with phygital (NCT07475741) — HTML: https://parkinsonspathways.com/trial/NCT07475741 — Markdown: https://parkinsonspathways.com/trial/NCT07475741.md
- Personalized stimulation to improve walking (NCT06350617) — HTML: https://parkinsonspathways.com/trial/NCT06350617 — Markdown: https://parkinsonspathways.com/trial/NCT06350617.md
- Reduce anxiety symptoms with mirtazapine (NCT06530290) — HTML: https://parkinsonspathways.com/trial/NCT06530290 — Markdown: https://parkinsonspathways.com/trial/NCT06530290.md
- Identify early striatal metabolite changes (NCT04735172) — HTML: https://parkinsonspathways.com/trial/NCT04735172 — Markdown: https://parkinsonspathways.com/trial/NCT04735172.md
- Improve walking with mixed reality (NCT06459154) — HTML: https://parkinsonspathways.com/trial/NCT06459154 — Markdown: https://parkinsonspathways.com/trial/NCT06459154.md
- Brain stimulation improves motor control (NCT04799470) — HTML: https://parkinsonspathways.com/trial/NCT04799470 — Markdown: https://parkinsonspathways.com/trial/NCT04799470.md
- Gentle ear stimulation improves movement (NCT06409338) — HTML: https://parkinsonspathways.com/trial/NCT06409338 — Markdown: https://parkinsonspathways.com/trial/NCT06409338.md
- Reduce neuroinflammation and slow progression (NCT07157735) — HTML: https://parkinsonspathways.com/trial/NCT07157735 — Markdown: https://parkinsonspathways.com/trial/NCT07157735.md
- Vibrating shoe improves walking stability (NCT06975059) — HTML: https://parkinsonspathways.com/trial/NCT06975059 — Markdown: https://parkinsonspathways.com/trial/NCT06975059.md
- Reduce falls with treadmill training (NCT07058285) — HTML: https://parkinsonspathways.com/trial/NCT07058285 — Markdown: https://parkinsonspathways.com/trial/NCT07058285.md
- Decrease resting hand tremor electrically (NCT06646510) — HTML: https://parkinsonspathways.com/trial/NCT06646510 — Markdown: https://parkinsonspathways.com/trial/NCT06646510.md
- Breathwork reduces stress and anxiety (NCT06581523) — HTML: https://parkinsonspathways.com/trial/NCT06581523 — Markdown: https://parkinsonspathways.com/trial/NCT06581523.md
- Vitamins lower blood homocysteine levels (NCT06772220) — HTML: https://parkinsonspathways.com/trial/NCT06772220 — Markdown: https://parkinsonspathways.com/trial/NCT06772220.md
- Detect serotonin loss in Parkinson (NCT05516732) — HTML: https://parkinsonspathways.com/trial/NCT05516732 — Markdown: https://parkinsonspathways.com/trial/NCT05516732.md
- Reduce cognitive decline through exercise (NCT07324330) — HTML: https://parkinsonspathways.com/trial/NCT07324330 — Markdown: https://parkinsonspathways.com/trial/NCT07324330.md
- Increase walking distance and endurance (NCT06859528) — HTML: https://parkinsonspathways.com/trial/NCT06859528 — Markdown: https://parkinsonspathways.com/trial/NCT06859528.md
- Rebalance neurotransmitter precursors with supplement (NCT07115563) — HTML: https://parkinsonspathways.com/trial/NCT07115563 — Markdown: https://parkinsonspathways.com/trial/NCT07115563.md
- Detect early loss of dopamine (NCT06456684) — HTML: https://parkinsonspathways.com/trial/NCT06456684 — Markdown: https://parkinsonspathways.com/trial/NCT06456684.md
- Improve electrode placement during surgery (NCT05550714) — HTML: https://parkinsonspathways.com/trial/NCT05550714 — Markdown: https://parkinsonspathways.com/trial/NCT05550714.md
- Predict treatment response from genetics (NCT03523052) — HTML: https://parkinsonspathways.com/trial/NCT03523052 — Markdown: https://parkinsonspathways.com/trial/NCT03523052.md
- Predict falls using wearable technology (NCT07281755) — HTML: https://parkinsonspathways.com/trial/NCT07281755 — Markdown: https://parkinsonspathways.com/trial/NCT07281755.md
- Map rescue medication dosing patterns (NCT07145190) — HTML: https://parkinsonspathways.com/trial/NCT07145190 — Markdown: https://parkinsonspathways.com/trial/NCT07145190.md
- New medication restores daily motivation (NCT07461220) — HTML: https://parkinsonspathways.com/trial/NCT07461220 — Markdown: https://parkinsonspathways.com/trial/NCT07461220.md
- Blood tests predict dementia progression (NCT06529744) — HTML: https://parkinsonspathways.com/trial/NCT06529744 — Markdown: https://parkinsonspathways.com/trial/NCT06529744.md
- Improve attention during brain stimulation (NCT06899022) — HTML: https://parkinsonspathways.com/trial/NCT06899022 — Markdown: https://parkinsonspathways.com/trial/NCT06899022.md
- Detect walking and balance problems (NCT07281794) — HTML: https://parkinsonspathways.com/trial/NCT07281794 — Markdown: https://parkinsonspathways.com/trial/NCT07281794.md
- Reduce off time and fluctuations (NCT07219927) — HTML: https://parkinsonspathways.com/trial/NCT07219927 — Markdown: https://parkinsonspathways.com/trial/NCT07219927.md
- Reduce tremor using Medtronic Activa (NCT01581580) — HTML: https://parkinsonspathways.com/trial/NCT01581580 — Markdown: https://parkinsonspathways.com/trial/NCT01581580.md
- Measure restless leg syndrome prevalence (NCT06684782) — HTML: https://parkinsonspathways.com/trial/NCT06684782 — Markdown: https://parkinsonspathways.com/trial/NCT06684782.md
- Reduce tremor and movement stiffness (NCT07572903) — HTML: https://parkinsonspathways.com/trial/NCT07572903 — Markdown: https://parkinsonspathways.com/trial/NCT07572903.md
- Improve balance with motor imagery (NCT06154356) — HTML: https://parkinsonspathways.com/trial/NCT06154356 — Markdown: https://parkinsonspathways.com/trial/NCT06154356.md
- Ear stimulation slows Parkinson progression (NCT06665113) — HTML: https://parkinsonspathways.com/trial/NCT06665113 — Markdown: https://parkinsonspathways.com/trial/NCT06665113.md
- Enhance home walking and balance (NCT06617884) — HTML: https://parkinsonspathways.com/trial/NCT06617884 — Markdown: https://parkinsonspathways.com/trial/NCT06617884.md
- Improve cognition through brain stimulation (NCT06399731) — HTML: https://parkinsonspathways.com/trial/NCT06399731 — Markdown: https://parkinsonspathways.com/trial/NCT06399731.md
- Brain stimulation improves daily motivation (NCT05065151) — HTML: https://parkinsonspathways.com/trial/NCT05065151 — Markdown: https://parkinsonspathways.com/trial/NCT05065151.md
- Improve gait through smartphone training (NCT07380737) — HTML: https://parkinsonspathways.com/trial/NCT07380737 — Markdown: https://parkinsonspathways.com/trial/NCT07380737.md
- Build strength and improve walking (NCT07498296) — HTML: https://parkinsonspathways.com/trial/NCT07498296 — Markdown: https://parkinsonspathways.com/trial/NCT07498296.md
- Improve balance using telerehabilitation games (NCT05773885) — HTML: https://parkinsonspathways.com/trial/NCT05773885 — Markdown: https://parkinsonspathways.com/trial/NCT05773885.md
- Personalize brain stimulation to symptoms (NCT07336199) — HTML: https://parkinsonspathways.com/trial/NCT07336199 — Markdown: https://parkinsonspathways.com/trial/NCT07336199.md
- Distinguish essential tremor from Parkinsons (NCT06378619) — HTML: https://parkinsonspathways.com/trial/NCT06378619 — Markdown: https://parkinsonspathways.com/trial/NCT06378619.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only — no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml) — includes Learn and PD-trial Markdown twins
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml) — references the main sitemap plus paginated child sitemaps for every universal-mirror Markdown URL
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)