# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 506 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated** — Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror** — A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Selected content families expose clean Markdown twins (append `.md` to the URL) with YAML frontmatter, intended for LLM ingestion. Supported patterns: `/learn/{slug}.md`, `/trial/{nctId}.md`, `/trials-near-me.md`, `/trials-near-me/{city}.md`, `/trials/{type}/{slug}.md`, `/trials/eu/{euctId}.md`. Pages such as `/`, `/about`, `/trials`, `/insights`, `/match`, and `/digest` do not have Markdown twins.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 506 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated — Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last? — HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last — Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials — HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials — Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- How to Spot a Questionable Clinical Trial — HTML: https://parkinsonspathways.com/learn/how-to-spot-a-questionable-clinical-trial — Markdown: https://parkinsonspathways.com/learn/how-to-spot-a-questionable-clinical-trial.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials — HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know — HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo? — HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo — Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- How Close Is a Cure for Parkinson's Disease? — HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know — HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials — Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work? — HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work — Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis — HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis — Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says — HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk — Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials — HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials — Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care — HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons — Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons — HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons — Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists — HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists — Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared — HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared — Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research — HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research — Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md
- tavapadon-new-parkinsons-drug-2026 — HTML: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026 — Markdown: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026.md
- state-of-parkinsons-clinical-trials — HTML: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials.md
- where-parkinsons-clinical-trials-happen — HTML: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen — Markdown: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen.md

## PD Curated — Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). Append `.md` to any `/trial/{nctId}` URL in the sitemap to reach its twin; below are the 50 most recently updated for quick discovery.

- Identify neural causes of dysphagia (NCT07299448) — HTML: https://parkinsonspathways.com/trial/NCT07299448 — Markdown: https://parkinsonspathways.com/trial/NCT07299448.md
- Improve balance using Segway training (NCT05982730) — HTML: https://parkinsonspathways.com/trial/NCT05982730 — Markdown: https://parkinsonspathways.com/trial/NCT05982730.md
- Improve walking stability with exercise (NCT07618728) — HTML: https://parkinsonspathways.com/trial/NCT07618728 — Markdown: https://parkinsonspathways.com/trial/NCT07618728.md
- Nasal spray reduces off episodes (NCT07156773) — HTML: https://parkinsonspathways.com/trial/NCT07156773 — Markdown: https://parkinsonspathways.com/trial/NCT07156773.md
- Change stimulation to improve balance (NCT05934747) — HTML: https://parkinsonspathways.com/trial/NCT05934747 — Markdown: https://parkinsonspathways.com/trial/NCT05934747.md
- New medication improves brain energy (NCT07322887) — HTML: https://parkinsonspathways.com/trial/NCT07322887 — Markdown: https://parkinsonspathways.com/trial/NCT07322887.md
- Identify rare genes causing Parkinsons (NCT05721911) — HTML: https://parkinsonspathways.com/trial/NCT05721911 — Markdown: https://parkinsonspathways.com/trial/NCT05721911.md
- Steady infusion reduces off periods (NCT06937034) — HTML: https://parkinsonspathways.com/trial/NCT06937034 — Markdown: https://parkinsonspathways.com/trial/NCT06937034.md
- Reduce apathy and boost motivation (NCT07399496) — HTML: https://parkinsonspathways.com/trial/NCT07399496 — Markdown: https://parkinsonspathways.com/trial/NCT07399496.md
- Saliva test detects Parkinson earlier (NCT06869135) — HTML: https://parkinsonspathways.com/trial/NCT06869135 — Markdown: https://parkinsonspathways.com/trial/NCT06869135.md
- Assess safety of gas medicine (NCT07005180) — HTML: https://parkinsonspathways.com/trial/NCT07005180 — Markdown: https://parkinsonspathways.com/trial/NCT07005180.md
- Surgical brain stimulation reduces impulsivity (NCT06498349) — HTML: https://parkinsonspathways.com/trial/NCT06498349 — Markdown: https://parkinsonspathways.com/trial/NCT06498349.md
- Predict benefit from brain stimulation (NCT07376278) — HTML: https://parkinsonspathways.com/trial/NCT07376278 — Markdown: https://parkinsonspathways.com/trial/NCT07376278.md
- Adaptive stimulation improves motor control (NCT07216976) — HTML: https://parkinsonspathways.com/trial/NCT07216976 — Markdown: https://parkinsonspathways.com/trial/NCT07216976.md
- Vibrating shoe increases walking speed (NCT07308418) — HTML: https://parkinsonspathways.com/trial/NCT07308418 — Markdown: https://parkinsonspathways.com/trial/NCT07308418.md
- Treat Parkinsons depression with ketamine (NCT06402955) — HTML: https://parkinsonspathways.com/trial/NCT06402955 — Markdown: https://parkinsonspathways.com/trial/NCT06402955.md
- Treat Parkinson depression with probiotics (NCT05568498) — HTML: https://parkinsonspathways.com/trial/NCT05568498 — Markdown: https://parkinsonspathways.com/trial/NCT05568498.md
- Describe symptoms and blood tests (NCT03523052) — HTML: https://parkinsonspathways.com/trial/NCT03523052 — Markdown: https://parkinsonspathways.com/trial/NCT03523052.md
- Identify candidates for gene therapy (NCT06151002) — HTML: https://parkinsonspathways.com/trial/NCT06151002 — Markdown: https://parkinsonspathways.com/trial/NCT06151002.md
- Improve speech with brain stimulation (NCT07568067) — HTML: https://parkinsonspathways.com/trial/NCT07568067 — Markdown: https://parkinsonspathways.com/trial/NCT07568067.md
- Reduce tremor and movement fluctuations (NCT07166757) — HTML: https://parkinsonspathways.com/trial/NCT07166757 — Markdown: https://parkinsonspathways.com/trial/NCT07166757.md
- Detect serotonin loss in Parkinson (NCT05516732) — HTML: https://parkinsonspathways.com/trial/NCT05516732 — Markdown: https://parkinsonspathways.com/trial/NCT05516732.md
- Distinguish reflexive tightness from stiffness (NCT06596187) — HTML: https://parkinsonspathways.com/trial/NCT06596187 — Markdown: https://parkinsonspathways.com/trial/NCT06596187.md
- Protect substantia nigra dopamine neurons (NCT06683378) — HTML: https://parkinsonspathways.com/trial/NCT06683378 — Markdown: https://parkinsonspathways.com/trial/NCT06683378.md
- Reduce wearing off motor fluctuations (NCT07403799) — HTML: https://parkinsonspathways.com/trial/NCT07403799 — Markdown: https://parkinsonspathways.com/trial/NCT07403799.md
- Improve ability to stop actions (NCT04735458) — HTML: https://parkinsonspathways.com/trial/NCT04735458 — Markdown: https://parkinsonspathways.com/trial/NCT04735458.md
- Measure dance exercise energy expenditure (NCT06425731) — HTML: https://parkinsonspathways.com/trial/NCT06425731 — Markdown: https://parkinsonspathways.com/trial/NCT06425731.md
- Improve upper limb motor learning (NCT05960331) — HTML: https://parkinsonspathways.com/trial/NCT05960331 — Markdown: https://parkinsonspathways.com/trial/NCT05960331.md
- Improve trunk posture and balance (NCT07610031) — HTML: https://parkinsonspathways.com/trial/NCT07610031 — Markdown: https://parkinsonspathways.com/trial/NCT07610031.md
- Reduce freezing episodes while walking (NCT06848205) — HTML: https://parkinsonspathways.com/trial/NCT06848205 — Markdown: https://parkinsonspathways.com/trial/NCT06848205.md
- Measure emotional response to music (NCT06688968) — HTML: https://parkinsonspathways.com/trial/NCT06688968 — Markdown: https://parkinsonspathways.com/trial/NCT06688968.md
- Slow Parkinson progression with telmisartan (NCT07207057) — HTML: https://parkinsonspathways.com/trial/NCT07207057 — Markdown: https://parkinsonspathways.com/trial/NCT07207057.md
- Slow thinking decline via activity (NCT07324330) — HTML: https://parkinsonspathways.com/trial/NCT07324330 — Markdown: https://parkinsonspathways.com/trial/NCT07324330.md
- Vitamin D normalizes brain waves (NCT07096336) — HTML: https://parkinsonspathways.com/trial/NCT07096336 — Markdown: https://parkinsonspathways.com/trial/NCT07096336.md
- Boost Parkinson patients physical activity (NCT06962930) — HTML: https://parkinsonspathways.com/trial/NCT06962930 — Markdown: https://parkinsonspathways.com/trial/NCT06962930.md
- Improve walking and standing balance (NCT06615115) — HTML: https://parkinsonspathways.com/trial/NCT06615115 — Markdown: https://parkinsonspathways.com/trial/NCT06615115.md
- Neck drainage surgery slows progression (NCT06852352) — HTML: https://parkinsonspathways.com/trial/NCT06852352 — Markdown: https://parkinsonspathways.com/trial/NCT06852352.md
- Stem cell surgery improves walking (NCT07106021) — HTML: https://parkinsonspathways.com/trial/NCT07106021 — Markdown: https://parkinsonspathways.com/trial/NCT07106021.md
- Document motor complications despite medication (NCT07330258) — HTML: https://parkinsonspathways.com/trial/NCT07330258 — Markdown: https://parkinsonspathways.com/trial/NCT07330258.md
- Improve swallowing through breath training (NCT07606547) — HTML: https://parkinsonspathways.com/trial/NCT07606547 — Markdown: https://parkinsonspathways.com/trial/NCT07606547.md
- Reduce forward and sideways leaning (NCT07010328) — HTML: https://parkinsonspathways.com/trial/NCT07010328 — Markdown: https://parkinsonspathways.com/trial/NCT07010328.md
- Replace lost movement brain cells (NCT06167681) — HTML: https://parkinsonspathways.com/trial/NCT06167681 — Markdown: https://parkinsonspathways.com/trial/NCT06167681.md
- Early Parkinsons detection from gut (NCT05347407) — HTML: https://parkinsonspathways.com/trial/NCT05347407 — Markdown: https://parkinsonspathways.com/trial/NCT05347407.md
- Exoskeleton improves balance while walking (NCT07567482) — HTML: https://parkinsonspathways.com/trial/NCT07567482 — Markdown: https://parkinsonspathways.com/trial/NCT07567482.md
- Reduce off time and fluctuations (NCT07219927) — HTML: https://parkinsonspathways.com/trial/NCT07219927 — Markdown: https://parkinsonspathways.com/trial/NCT07219927.md
- Reduce drooling and improve swallowing (NCT04664634) — HTML: https://parkinsonspathways.com/trial/NCT04664634 — Markdown: https://parkinsonspathways.com/trial/NCT04664634.md
- Timed stimulation reduces hand tremor (NCT06993571) — HTML: https://parkinsonspathways.com/trial/NCT06993571 — Markdown: https://parkinsonspathways.com/trial/NCT06993571.md
- Track tremor severity over time (NCT05066763) — HTML: https://parkinsonspathways.com/trial/NCT05066763 — Markdown: https://parkinsonspathways.com/trial/NCT05066763.md
- New medication targets brain inflammation (NCT07142044) — HTML: https://parkinsonspathways.com/trial/NCT07142044 — Markdown: https://parkinsonspathways.com/trial/NCT07142044.md
- Improve movement by filtering sensations (NCT05482126) — HTML: https://parkinsonspathways.com/trial/NCT05482126 — Markdown: https://parkinsonspathways.com/trial/NCT05482126.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only — no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml) — clean HTML URLs for every public page (only `/trial/{nctId}`, `/learn/{slug}`, `/trials-near-me`, `/trials-near-me/{city}`, `/trials/{type}/{slug}`, and `/trials/eu/{euctId}` entries support a `.md` twin)
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml) — references the main sitemap
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)