# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 503 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated** — Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror** — A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Every public page has a clean Markdown twin at `<page-url>.md` with frontmatter, intended for LLM ingestion.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 503 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated — Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last? — HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last — Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials — HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials — Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials — HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know — HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo? — HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo — Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- How Close Is a Cure for Parkinson's Disease? — HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know — HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials — Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work? — HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work — Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis — HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis — Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says — HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk — Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials — HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials — Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care — HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons — Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons — HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons — Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists — HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists — Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared — HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared — Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research — HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research — Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md
- tavapadon-new-parkinsons-drug-2026 — HTML: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026 — Markdown: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026.md
- state-of-parkinsons-clinical-trials — HTML: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials.md
- where-parkinsons-clinical-trials-happen — HTML: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen — Markdown: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen.md

## PD Curated — Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). The full set is in the sitemap; below are the 50 most recently updated for quick discovery.

- Probiotic cocktail delays Parkinson progression (NCT07619560) — HTML: https://parkinsonspathways.com/trial/NCT07619560 — Markdown: https://parkinsonspathways.com/trial/NCT07619560.md
- Improve walking stability with exercise (NCT07618728) — HTML: https://parkinsonspathways.com/trial/NCT07618728 — Markdown: https://parkinsonspathways.com/trial/NCT07618728.md
- Determine if sleep affects thinking (NCT07536490) — HTML: https://parkinsonspathways.com/trial/NCT07536490 — Markdown: https://parkinsonspathways.com/trial/NCT07536490.md
- Multitasking exercises improve arm strength (NCT07536542) — HTML: https://parkinsonspathways.com/trial/NCT07536542 — Markdown: https://parkinsonspathways.com/trial/NCT07536542.md
- Wearable cues reduce daily freezing (NCT06416345) — HTML: https://parkinsonspathways.com/trial/NCT06416345 — Markdown: https://parkinsonspathways.com/trial/NCT06416345.md
- Gentle ear stimulation improves movement (NCT06409338) — HTML: https://parkinsonspathways.com/trial/NCT06409338 — Markdown: https://parkinsonspathways.com/trial/NCT06409338.md
- Surgery to reduce protein buildup (NCT06852352) — HTML: https://parkinsonspathways.com/trial/NCT06852352 — Markdown: https://parkinsonspathways.com/trial/NCT06852352.md
- Detect Parkinson related brain changes (NCT06098612) — HTML: https://parkinsonspathways.com/trial/NCT06098612 — Markdown: https://parkinsonspathways.com/trial/NCT06098612.md
- Validate wearable assessment of walking (NCT05874739) — HTML: https://parkinsonspathways.com/trial/NCT05874739 — Markdown: https://parkinsonspathways.com/trial/NCT05874739.md
- Continuous medication reduces motor fluctuations (NCT06916507) — HTML: https://parkinsonspathways.com/trial/NCT06916507 — Markdown: https://parkinsonspathways.com/trial/NCT06916507.md
- Reduce gait freezing with cueing (NCT06733077) — HTML: https://parkinsonspathways.com/trial/NCT06733077 — Markdown: https://parkinsonspathways.com/trial/NCT06733077.md
- Brain stimulation reduces disabling tremor (NCT02119611) — HTML: https://parkinsonspathways.com/trial/NCT02119611 — Markdown: https://parkinsonspathways.com/trial/NCT02119611.md
- Gene therapy slows Parkinson progression (NCT07216066) — HTML: https://parkinsonspathways.com/trial/NCT07216066 — Markdown: https://parkinsonspathways.com/trial/NCT07216066.md
- Find drugs boosting cell cleanup (NCT05536388) — HTML: https://parkinsonspathways.com/trial/NCT05536388 — Markdown: https://parkinsonspathways.com/trial/NCT05536388.md
- Reduce movement problems with supplement (NCT07064005) — HTML: https://parkinsonspathways.com/trial/NCT07064005 — Markdown: https://parkinsonspathways.com/trial/NCT07064005.md
- Assess experimental pain in Parkinsons (NCT05981261) — HTML: https://parkinsonspathways.com/trial/NCT05981261 — Markdown: https://parkinsonspathways.com/trial/NCT05981261.md
- Test radotinib to slow progression (NCT04691661) — HTML: https://parkinsonspathways.com/trial/NCT04691661 — Markdown: https://parkinsonspathways.com/trial/NCT04691661.md
- Treat Parkinson depression with probiotics (NCT05568498) — HTML: https://parkinsonspathways.com/trial/NCT05568498 — Markdown: https://parkinsonspathways.com/trial/NCT05568498.md
- Reduce tremor slowness and stiffness (NCT04681534) — HTML: https://parkinsonspathways.com/trial/NCT04681534 — Markdown: https://parkinsonspathways.com/trial/NCT04681534.md
- Vitamin D normalizes brain waves (NCT07096336) — HTML: https://parkinsonspathways.com/trial/NCT07096336 — Markdown: https://parkinsonspathways.com/trial/NCT07096336.md
- Improve cognitive function with tributyrin (NCT07154511) — HTML: https://parkinsonspathways.com/trial/NCT07154511 — Markdown: https://parkinsonspathways.com/trial/NCT07154511.md
- Improve movement and speech function (NCT07568067) — HTML: https://parkinsonspathways.com/trial/NCT07568067 — Markdown: https://parkinsonspathways.com/trial/NCT07568067.md
- Improve walking speed through exercise (NCT07057219) — HTML: https://parkinsonspathways.com/trial/NCT07057219 — Markdown: https://parkinsonspathways.com/trial/NCT07057219.md
- Detect neck norepinephrine nerve loss (NCT05741151) — HTML: https://parkinsonspathways.com/trial/NCT05741151 — Markdown: https://parkinsonspathways.com/trial/NCT05741151.md
- Improve vision guided reaching ability (NCT05400499) — HTML: https://parkinsonspathways.com/trial/NCT05400499 — Markdown: https://parkinsonspathways.com/trial/NCT05400499.md
- Improve upper limb motor learning (NCT07028515) — HTML: https://parkinsonspathways.com/trial/NCT07028515 — Markdown: https://parkinsonspathways.com/trial/NCT07028515.md
- Improve balance using telerehabilitation games (NCT05773885) — HTML: https://parkinsonspathways.com/trial/NCT05773885 — Markdown: https://parkinsonspathways.com/trial/NCT05773885.md
- Reduce depressive symptoms in Parkinsons (NCT06455293) — HTML: https://parkinsonspathways.com/trial/NCT06455293 — Markdown: https://parkinsonspathways.com/trial/NCT06455293.md
- Identify markers predicting Parkinson progression (NCT02305147) — HTML: https://parkinsonspathways.com/trial/NCT02305147 — Markdown: https://parkinsonspathways.com/trial/NCT02305147.md
- Assess long term buntanetap safety (NCT07284784) — HTML: https://parkinsonspathways.com/trial/NCT07284784 — Markdown: https://parkinsonspathways.com/trial/NCT07284784.md
- Increase daily walking step count (NCT04848077) — HTML: https://parkinsonspathways.com/trial/NCT04848077 — Markdown: https://parkinsonspathways.com/trial/NCT04848077.md
- Predict Parkinson progression using neuroimaging (NCT07024875) — HTML: https://parkinsonspathways.com/trial/NCT07024875 — Markdown: https://parkinsonspathways.com/trial/NCT07024875.md
- Virtual reality improves walking coordination (NCT07250672) — HTML: https://parkinsonspathways.com/trial/NCT07250672 — Markdown: https://parkinsonspathways.com/trial/NCT07250672.md
- Mediterranean diet improves nutritional status (NCT07187739) — HTML: https://parkinsonspathways.com/trial/NCT07187739 — Markdown: https://parkinsonspathways.com/trial/NCT07187739.md
- Assess expiratory respiratory muscle strength (NCT07308795) — HTML: https://parkinsonspathways.com/trial/NCT07308795 — Markdown: https://parkinsonspathways.com/trial/NCT07308795.md
- Detect Parkinson and track severity (NCT07392411) — HTML: https://parkinsonspathways.com/trial/NCT07392411 — Markdown: https://parkinsonspathways.com/trial/NCT07392411.md
- Improve trunk posture and balance (NCT07610031) — HTML: https://parkinsonspathways.com/trial/NCT07610031 — Markdown: https://parkinsonspathways.com/trial/NCT07610031.md
- Driving simulator improves driving safety (NCT06320639) — HTML: https://parkinsonspathways.com/trial/NCT06320639 — Markdown: https://parkinsonspathways.com/trial/NCT06320639.md
- Aerobic exercise slows Parkinson progression (NCT05854524) — HTML: https://parkinsonspathways.com/trial/NCT05854524 — Markdown: https://parkinsonspathways.com/trial/NCT05854524.md
- Replace lost dopamine producing neurons (NCT06167681) — HTML: https://parkinsonspathways.com/trial/NCT06167681 — Markdown: https://parkinsonspathways.com/trial/NCT06167681.md
- Assess speech and swallowing function (NCT04706234) — HTML: https://parkinsonspathways.com/trial/NCT04706234 — Markdown: https://parkinsonspathways.com/trial/NCT04706234.md
- Lower brain inflammation using exercise (NCT06977204) — HTML: https://parkinsonspathways.com/trial/NCT06977204 — Markdown: https://parkinsonspathways.com/trial/NCT06977204.md
- Slow Parkinson brain cell loss (NCT07142044) — HTML: https://parkinsonspathways.com/trial/NCT07142044 — Markdown: https://parkinsonspathways.com/trial/NCT07142044.md
- Find early tests for Parkinson (NCT06846658) — HTML: https://parkinsonspathways.com/trial/NCT06846658 — Markdown: https://parkinsonspathways.com/trial/NCT06846658.md
- Improve walking using resistance training (NCT07378813) — HTML: https://parkinsonspathways.com/trial/NCT07378813 — Markdown: https://parkinsonspathways.com/trial/NCT07378813.md
- Slow Parkinson degeneration using Dserine (NCT07312110) — HTML: https://parkinsonspathways.com/trial/NCT07312110 — Markdown: https://parkinsonspathways.com/trial/NCT07312110.md
- Image brain cyclooxygenase related inflammation (NCT04396873) — HTML: https://parkinsonspathways.com/trial/NCT04396873 — Markdown: https://parkinsonspathways.com/trial/NCT04396873.md
- Sensing brain stimulation lengthens sleep (NCT05070013) — HTML: https://parkinsonspathways.com/trial/NCT05070013 — Markdown: https://parkinsonspathways.com/trial/NCT05070013.md
- Restore dopamine to improve walking (NCT05901818) — HTML: https://parkinsonspathways.com/trial/NCT05901818 — Markdown: https://parkinsonspathways.com/trial/NCT05901818.md
- Improve speech clarity and walking (NCT07588191) — HTML: https://parkinsonspathways.com/trial/NCT07588191 — Markdown: https://parkinsonspathways.com/trial/NCT07588191.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only — no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml) — includes Learn and PD-trial Markdown twins
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml) — references the main sitemap plus paginated child sitemaps for every universal-mirror Markdown URL
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)