# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 500 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated** — Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror** — A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Every public page has a clean Markdown twin at `<page-url>.md` with frontmatter, intended for LLM ingestion.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 500 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated — Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last? — HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last — Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials — HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials — Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials — HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know — HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo? — HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo — Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- How Close Is a Cure for Parkinson's Disease? — HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know — HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials — Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work? — HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work — Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis — HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis — Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says — HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk — Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials — HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials — Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care — HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons — Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md

## PD Curated — Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). The full set is in the sitemap; below are the 50 most recently updated for quick discovery.

- Cycling slows Parkinson disease progression (NCT06442033) — HTML: https://parkinsonspathways.com/trial/NCT06442033 — Markdown: https://parkinsonspathways.com/trial/NCT06442033.md
- Detect neck norepinephrine nerve loss (NCT05741151) — HTML: https://parkinsonspathways.com/trial/NCT05741151 — Markdown: https://parkinsonspathways.com/trial/NCT05741151.md
- Home neck stimulation improves walking (NCT06562569) — HTML: https://parkinsonspathways.com/trial/NCT06562569 — Markdown: https://parkinsonspathways.com/trial/NCT06562569.md
- Improve mobility with rotational exercises (NCT07442370) — HTML: https://parkinsonspathways.com/trial/NCT07442370 — Markdown: https://parkinsonspathways.com/trial/NCT07442370.md
- Improve daily functioning through teams (NCT05433441) — HTML: https://parkinsonspathways.com/trial/NCT05433441 — Markdown: https://parkinsonspathways.com/trial/NCT05433441.md
- Strengthen cough by forward flexion (NCT06955377) — HTML: https://parkinsonspathways.com/trial/NCT06955377 — Markdown: https://parkinsonspathways.com/trial/NCT06955377.md
- Reduce medication wearing off symptoms (NCT06145711) — HTML: https://parkinsonspathways.com/trial/NCT06145711 — Markdown: https://parkinsonspathways.com/trial/NCT06145711.md
- Improve walking and reduce stiffness (NCT07572071) — HTML: https://parkinsonspathways.com/trial/NCT07572071 — Markdown: https://parkinsonspathways.com/trial/NCT07572071.md
- Tenofovir slows Parkinson disease progression (NCT06356662) — HTML: https://parkinsonspathways.com/trial/NCT06356662 — Markdown: https://parkinsonspathways.com/trial/NCT06356662.md
- Complementary medicine to reduce stiffness (NCT07207096) — HTML: https://parkinsonspathways.com/trial/NCT07207096 — Markdown: https://parkinsonspathways.com/trial/NCT07207096.md
- Fast bodyweight training improves speed (NCT06646523) — HTML: https://parkinsonspathways.com/trial/NCT06646523 — Markdown: https://parkinsonspathways.com/trial/NCT06646523.md
- Improve upper limb motor learning (NCT05960331) — HTML: https://parkinsonspathways.com/trial/NCT05960331 — Markdown: https://parkinsonspathways.com/trial/NCT05960331.md
- Reduce motor and nonmotor symptoms (NCT06548256) — HTML: https://parkinsonspathways.com/trial/NCT06548256 — Markdown: https://parkinsonspathways.com/trial/NCT06548256.md
- Cell transplant reduces off time (NCT07080775) — HTML: https://parkinsonspathways.com/trial/NCT07080775 — Markdown: https://parkinsonspathways.com/trial/NCT07080775.md
- Individualized brain stimulation improves walking (NCT07570212) — HTML: https://parkinsonspathways.com/trial/NCT07570212 — Markdown: https://parkinsonspathways.com/trial/NCT07570212.md
- Predict Parkinson or dementia risk (NCT06629207) — HTML: https://parkinsonspathways.com/trial/NCT06629207 — Markdown: https://parkinsonspathways.com/trial/NCT06629207.md
- Improve intelligibility of Parkinson speech (NCT06815263) — HTML: https://parkinsonspathways.com/trial/NCT06815263 — Markdown: https://parkinsonspathways.com/trial/NCT06815263.md
- Separate Parkinson from similar disorders (NCT06490926) — HTML: https://parkinsonspathways.com/trial/NCT06490926 — Markdown: https://parkinsonspathways.com/trial/NCT06490926.md
- Improve walking with red light (NCT06916260) — HTML: https://parkinsonspathways.com/trial/NCT06916260 — Markdown: https://parkinsonspathways.com/trial/NCT06916260.md
- Decrease resting hand tremor electrically (NCT06646510) — HTML: https://parkinsonspathways.com/trial/NCT06646510 — Markdown: https://parkinsonspathways.com/trial/NCT06646510.md
- Ear stimulation slows Parkinson progression (NCT06665113) — HTML: https://parkinsonspathways.com/trial/NCT06665113 — Markdown: https://parkinsonspathways.com/trial/NCT06665113.md
- Reduce hallucinations without worsening movement (NCT04373317) — HTML: https://parkinsonspathways.com/trial/NCT04373317 — Markdown: https://parkinsonspathways.com/trial/NCT04373317.md
- Shorten daily periods without movement (NCT07422675) — HTML: https://parkinsonspathways.com/trial/NCT07422675 — Markdown: https://parkinsonspathways.com/trial/NCT07422675.md
- Improve motor function using StimSearch (NCT06205043) — HTML: https://parkinsonspathways.com/trial/NCT06205043 — Markdown: https://parkinsonspathways.com/trial/NCT06205043.md
- Ear stimulation reduces standing lightheadedness (NCT07557706) — HTML: https://parkinsonspathways.com/trial/NCT07557706 — Markdown: https://parkinsonspathways.com/trial/NCT07557706.md
- Improve social engagement and mood (NCT06385184) — HTML: https://parkinsonspathways.com/trial/NCT06385184 — Markdown: https://parkinsonspathways.com/trial/NCT06385184.md
- Spinal cord stimulation reduces freezing (NCT06798844) — HTML: https://parkinsonspathways.com/trial/NCT06798844 — Markdown: https://parkinsonspathways.com/trial/NCT06798844.md
- Improve sleep using brain pulses (NCT07110376) — HTML: https://parkinsonspathways.com/trial/NCT07110376 — Markdown: https://parkinsonspathways.com/trial/NCT07110376.md
- Improve walking speed through exercise (NCT07057219) — HTML: https://parkinsonspathways.com/trial/NCT07057219 — Markdown: https://parkinsonspathways.com/trial/NCT07057219.md
- Reduce tremor stiffness and slowness (NCT05557864) — HTML: https://parkinsonspathways.com/trial/NCT05557864 — Markdown: https://parkinsonspathways.com/trial/NCT05557864.md
- Reduce tremor stiffness and slowness (NCT02071134) — HTML: https://parkinsonspathways.com/trial/NCT02071134 — Markdown: https://parkinsonspathways.com/trial/NCT02071134.md
- Reduce forward and sideways leaning (NCT07010328) — HTML: https://parkinsonspathways.com/trial/NCT07010328 — Markdown: https://parkinsonspathways.com/trial/NCT07010328.md
- Enhance Parkinsons cognition via exercise (NCT06580977) — HTML: https://parkinsonspathways.com/trial/NCT06580977 — Markdown: https://parkinsonspathways.com/trial/NCT06580977.md
- Assess propofol effects on brain (NCT05895019) — HTML: https://parkinsonspathways.com/trial/NCT05895019 — Markdown: https://parkinsonspathways.com/trial/NCT05895019.md
- Improve balance through arm function (NCT06591975) — HTML: https://parkinsonspathways.com/trial/NCT06591975 — Markdown: https://parkinsonspathways.com/trial/NCT06591975.md
- Assess Parkinson symptoms in Italian (NCT07316751) — HTML: https://parkinsonspathways.com/trial/NCT07316751 — Markdown: https://parkinsonspathways.com/trial/NCT07316751.md
- Reduce motor symptoms using neurofeedback (NCT06582355) — HTML: https://parkinsonspathways.com/trial/NCT06582355 — Markdown: https://parkinsonspathways.com/trial/NCT06582355.md
- Reduce tremor and movement fluctuations (NCT06909045) — HTML: https://parkinsonspathways.com/trial/NCT06909045 — Markdown: https://parkinsonspathways.com/trial/NCT06909045.md
- Improve walking endurance through exercise (NCT07221266) — HTML: https://parkinsonspathways.com/trial/NCT07221266 — Markdown: https://parkinsonspathways.com/trial/NCT07221266.md
- Reduce hallucinations without worsening movement (NCT05824728) — HTML: https://parkinsonspathways.com/trial/NCT05824728 — Markdown: https://parkinsonspathways.com/trial/NCT05824728.md
- Improve walking with Parkinson medication (NCT02994719) — HTML: https://parkinsonspathways.com/trial/NCT02994719 — Markdown: https://parkinsonspathways.com/trial/NCT02994719.md
- Identify cognitive decline in Parkinsons (NCT03402919) — HTML: https://parkinsonspathways.com/trial/NCT03402919 — Markdown: https://parkinsonspathways.com/trial/NCT03402919.md
- Improve mood through caudate stimulation (NCT07409207) — HTML: https://parkinsonspathways.com/trial/NCT07409207 — Markdown: https://parkinsonspathways.com/trial/NCT07409207.md
- Relieve Parkinson constipation through acupuncture (NCT06390761) — HTML: https://parkinsonspathways.com/trial/NCT06390761 — Markdown: https://parkinsonspathways.com/trial/NCT06390761.md
- Increase energy conservation self efficacy (NCT07094269) — HTML: https://parkinsonspathways.com/trial/NCT07094269 — Markdown: https://parkinsonspathways.com/trial/NCT07094269.md
- Differentiate neurodegenerative diseases using saliva (NCT06869135) — HTML: https://parkinsonspathways.com/trial/NCT06869135 — Markdown: https://parkinsonspathways.com/trial/NCT06869135.md
- Increase daily steady on time (NCT07138560) — HTML: https://parkinsonspathways.com/trial/NCT07138560 — Markdown: https://parkinsonspathways.com/trial/NCT07138560.md
- Improve thinking through implanted stimulation (NCT06518824) — HTML: https://parkinsonspathways.com/trial/NCT06518824 — Markdown: https://parkinsonspathways.com/trial/NCT06518824.md
- Exercise improves walking and thinking (NCT07478146) — HTML: https://parkinsonspathways.com/trial/NCT07478146 — Markdown: https://parkinsonspathways.com/trial/NCT07478146.md
- Acupuncture reduces tremor and slowness (NCT06304285) — HTML: https://parkinsonspathways.com/trial/NCT06304285 — Markdown: https://parkinsonspathways.com/trial/NCT06304285.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only — no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml) — includes Learn and PD-trial Markdown twins
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml) — references the main sitemap plus paginated child sitemaps for every universal-mirror Markdown URL
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)