# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 503 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated** — Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror** — A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Selected content families expose clean Markdown twins (append `.md` to the URL) with YAML frontmatter, intended for LLM ingestion. Supported patterns: `/learn/{slug}.md`, `/trial/{nctId}.md`, `/trials-near-me.md`, `/trials-near-me/{city}.md`, `/trials/{type}/{slug}.md`, `/trials/eu/{euctId}.md`. Pages such as `/`, `/about`, `/trials`, `/insights`, `/match`, and `/digest` do not have Markdown twins.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 503 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated — Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last? — HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last — Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials — HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials — Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- How to Spot a Questionable Clinical Trial — HTML: https://parkinsonspathways.com/learn/how-to-spot-a-questionable-clinical-trial — Markdown: https://parkinsonspathways.com/learn/how-to-spot-a-questionable-clinical-trial.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials — HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know — HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo? — HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo — Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- How Close Is a Cure for Parkinson's Disease? — HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know — HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials — Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work? — HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work — Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis — HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis — Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says — HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk — Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials — HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials — Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care — HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons — Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons — HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons — Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists — HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists — Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared — HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared — Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research — HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research — Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md
- tavapadon-new-parkinsons-drug-2026 — HTML: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026 — Markdown: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026.md
- state-of-parkinsons-clinical-trials — HTML: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials.md
- where-parkinsons-clinical-trials-happen — HTML: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen — Markdown: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen.md

## PD Curated — Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). Append `.md` to any `/trial/{nctId}` URL in the sitemap to reach its twin; below are the 50 most recently updated for quick discovery.

- Reduce tremor and movement stiffness (NCT07572903) — HTML: https://parkinsonspathways.com/trial/NCT07572903 — Markdown: https://parkinsonspathways.com/trial/NCT07572903.md
- Reduce camptocormia pain with stimulation (NCT06291051) — HTML: https://parkinsonspathways.com/trial/NCT06291051 — Markdown: https://parkinsonspathways.com/trial/NCT06291051.md
- Reduce freezing of gait episodes (NCT05292794) — HTML: https://parkinsonspathways.com/trial/NCT05292794 — Markdown: https://parkinsonspathways.com/trial/NCT05292794.md
- Improve walking endurance through exercise (NCT07221266) — HTML: https://parkinsonspathways.com/trial/NCT07221266 — Markdown: https://parkinsonspathways.com/trial/NCT07221266.md
- Improve motor symptoms via glucose (NCT05998772) — HTML: https://parkinsonspathways.com/trial/NCT05998772 — Markdown: https://parkinsonspathways.com/trial/NCT05998772.md
- Identify why physical activity declines (NCT07585409) — HTML: https://parkinsonspathways.com/trial/NCT07585409 — Markdown: https://parkinsonspathways.com/trial/NCT07585409.md
- Reduce medication wearing off symptoms (NCT06145711) — HTML: https://parkinsonspathways.com/trial/NCT06145711 — Markdown: https://parkinsonspathways.com/trial/NCT06145711.md
- Test drug safety in Parkinson (NCT06466525) — HTML: https://parkinsonspathways.com/trial/NCT06466525 — Markdown: https://parkinsonspathways.com/trial/NCT06466525.md
- Test febuxostat and inosine neuroprotection (NCT07170475) — HTML: https://parkinsonspathways.com/trial/NCT07170475 — Markdown: https://parkinsonspathways.com/trial/NCT07170475.md
- Improve walking stability with exercise (NCT07618728) — HTML: https://parkinsonspathways.com/trial/NCT07618728 — Markdown: https://parkinsonspathways.com/trial/NCT07618728.md
- Reduce predictable wearing off periods (NCT06765668) — HTML: https://parkinsonspathways.com/trial/NCT06765668 — Markdown: https://parkinsonspathways.com/trial/NCT06765668.md
- Improve balance through arm function (NCT06591975) — HTML: https://parkinsonspathways.com/trial/NCT06591975 — Markdown: https://parkinsonspathways.com/trial/NCT06591975.md
- Reduce toxic brain protein clumps (NCT06565195) — HTML: https://parkinsonspathways.com/trial/NCT06565195 — Markdown: https://parkinsonspathways.com/trial/NCT06565195.md
- Create personalized stem cell therapies (NCT00874783) — HTML: https://parkinsonspathways.com/trial/NCT00874783 — Markdown: https://parkinsonspathways.com/trial/NCT00874783.md
- Improve cognition through brain stimulation (NCT06399731) — HTML: https://parkinsonspathways.com/trial/NCT06399731 — Markdown: https://parkinsonspathways.com/trial/NCT06399731.md
- Detect neck norepinephrine nerve loss (NCT05741151) — HTML: https://parkinsonspathways.com/trial/NCT05741151 — Markdown: https://parkinsonspathways.com/trial/NCT05741151.md
- Reduce motor and nonmotor symptoms (NCT06548256) — HTML: https://parkinsonspathways.com/trial/NCT06548256 — Markdown: https://parkinsonspathways.com/trial/NCT06548256.md
- Prevent mania after brain stimulation (NCT05444907) — HTML: https://parkinsonspathways.com/trial/NCT05444907 — Markdown: https://parkinsonspathways.com/trial/NCT05444907.md
- Shorten daily periods without movement (NCT07422675) — HTML: https://parkinsonspathways.com/trial/NCT07422675 — Markdown: https://parkinsonspathways.com/trial/NCT07422675.md
- Prevent tremor relapse after thalamotomy (NCT07284719) — HTML: https://parkinsonspathways.com/trial/NCT07284719 — Markdown: https://parkinsonspathways.com/trial/NCT07284719.md
- Reduce freezing episodes during walking (NCT06630702) — HTML: https://parkinsonspathways.com/trial/NCT06630702 — Markdown: https://parkinsonspathways.com/trial/NCT06630702.md
- Reduce freezing and improve walking (NCT06791902) — HTML: https://parkinsonspathways.com/trial/NCT06791902 — Markdown: https://parkinsonspathways.com/trial/NCT06791902.md
- Reduce drooling and improve swallowing (NCT04664634) — HTML: https://parkinsonspathways.com/trial/NCT04664634 — Markdown: https://parkinsonspathways.com/trial/NCT04664634.md
- Link gut microbiome to tremor (NCT06848192) — HTML: https://parkinsonspathways.com/trial/NCT06848192 — Markdown: https://parkinsonspathways.com/trial/NCT06848192.md
- Identify modifiable factors slowing progression (NCT02194816) — HTML: https://parkinsonspathways.com/trial/NCT02194816 — Markdown: https://parkinsonspathways.com/trial/NCT02194816.md
- Blood test tracks Parkinson progression (NCT05769699) — HTML: https://parkinsonspathways.com/trial/NCT05769699 — Markdown: https://parkinsonspathways.com/trial/NCT05769699.md
- Boost Parkinson patients physical activity (NCT06962930) — HTML: https://parkinsonspathways.com/trial/NCT06962930 — Markdown: https://parkinsonspathways.com/trial/NCT06962930.md
- Map inflammation to guide treatment (NCT03457493) — HTML: https://parkinsonspathways.com/trial/NCT03457493 — Markdown: https://parkinsonspathways.com/trial/NCT03457493.md
- Slow Parkinson brain cell loss (NCT07142044) — HTML: https://parkinsonspathways.com/trial/NCT07142044 — Markdown: https://parkinsonspathways.com/trial/NCT07142044.md
- Test imaging tracer for Parkinson (NCT07617688) — HTML: https://parkinsonspathways.com/trial/NCT07617688 — Markdown: https://parkinsonspathways.com/trial/NCT07617688.md
- Map Parkinson progression in carriers (NCT03523104) — HTML: https://parkinsonspathways.com/trial/NCT03523104 — Markdown: https://parkinsonspathways.com/trial/NCT03523104.md
- Predict falls due to freezing (NCT07386015) — HTML: https://parkinsonspathways.com/trial/NCT07386015 — Markdown: https://parkinsonspathways.com/trial/NCT07386015.md
- Exoskeleton improves balance while walking (NCT07567482) — HTML: https://parkinsonspathways.com/trial/NCT07567482 — Markdown: https://parkinsonspathways.com/trial/NCT07567482.md
- Improve sleep using vestibular stimulation (NCT06386497) — HTML: https://parkinsonspathways.com/trial/NCT06386497 — Markdown: https://parkinsonspathways.com/trial/NCT06386497.md
- Improve sleep using brain pulses (NCT07110376) — HTML: https://parkinsonspathways.com/trial/NCT07110376 — Markdown: https://parkinsonspathways.com/trial/NCT07110376.md
- Probiotic cocktail delays Parkinson progression (NCT07619560) — HTML: https://parkinsonspathways.com/trial/NCT07619560 — Markdown: https://parkinsonspathways.com/trial/NCT07619560.md
- Characterize hearing changes in Parkinson (NCT07083089) — HTML: https://parkinsonspathways.com/trial/NCT07083089 — Markdown: https://parkinsonspathways.com/trial/NCT07083089.md
- Gene therapy slows Parkinson progression (NCT07216066) — HTML: https://parkinsonspathways.com/trial/NCT07216066 — Markdown: https://parkinsonspathways.com/trial/NCT07216066.md
- Improve hand dexterity with phygital (NCT07475741) — HTML: https://parkinsonspathways.com/trial/NCT07475741 — Markdown: https://parkinsonspathways.com/trial/NCT07475741.md
- Reduce early Parkinsons motor symptoms (NCT06874803) — HTML: https://parkinsonspathways.com/trial/NCT06874803 — Markdown: https://parkinsonspathways.com/trial/NCT06874803.md
- Test intranasal insulin and glutathione (NCT05266417) — HTML: https://parkinsonspathways.com/trial/NCT05266417 — Markdown: https://parkinsonspathways.com/trial/NCT05266417.md
- Increase daily steady on time (NCT07138560) — HTML: https://parkinsonspathways.com/trial/NCT07138560 — Markdown: https://parkinsonspathways.com/trial/NCT07138560.md
- Brain stimulation improves stopping movements (NCT04061135) — HTML: https://parkinsonspathways.com/trial/NCT04061135 — Markdown: https://parkinsonspathways.com/trial/NCT04061135.md
- Improve side to side balance (NCT07568951) — HTML: https://parkinsonspathways.com/trial/NCT07568951 — Markdown: https://parkinsonspathways.com/trial/NCT07568951.md
- Improve attention memory and walking (NCT05968703) — HTML: https://parkinsonspathways.com/trial/NCT05968703 — Markdown: https://parkinsonspathways.com/trial/NCT05968703.md
- Assess taste function in Parkinsons (NCT06439355) — HTML: https://parkinsonspathways.com/trial/NCT06439355 — Markdown: https://parkinsonspathways.com/trial/NCT06439355.md
- Differentiate neurodegenerative diseases using saliva (NCT06869135) — HTML: https://parkinsonspathways.com/trial/NCT06869135 — Markdown: https://parkinsonspathways.com/trial/NCT06869135.md
- Reduce slowness stiffness and tremor (NCT05268887) — HTML: https://parkinsonspathways.com/trial/NCT05268887 — Markdown: https://parkinsonspathways.com/trial/NCT05268887.md
- Improve balance using telerehabilitation games (NCT05773885) — HTML: https://parkinsonspathways.com/trial/NCT05773885 — Markdown: https://parkinsonspathways.com/trial/NCT05773885.md
- Reduce Parkinson progression with antiinflammatory (NCT07370532) — HTML: https://parkinsonspathways.com/trial/NCT07370532 — Markdown: https://parkinsonspathways.com/trial/NCT07370532.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only — no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml) — clean HTML URLs for every public page (only `/trial/{nctId}`, `/learn/{slug}`, `/trials-near-me`, `/trials-near-me/{city}`, `/trials/{type}/{slug}`, and `/trials/eu/{euctId}` entries support a `.md` twin)
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml) — references the main sitemap
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)