# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 504 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated** — Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror** — A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Selected content families expose clean Markdown twins (append `.md` to the URL) with YAML frontmatter, intended for LLM ingestion. Supported patterns: `/learn/{slug}.md`, `/trial/{nctId}.md`, `/trials-near-me.md`, `/trials-near-me/{city}.md`, `/trials/{type}/{slug}.md`, `/trials/eu/{euctId}.md`. Pages such as `/`, `/about`, `/trials`, `/insights`, `/match`, and `/digest` do not have Markdown twins.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 504 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated — Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last? — HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last — Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials — HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials — Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials — HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know — HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo? — HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo — Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- How Close Is a Cure for Parkinson's Disease? — HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know — HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials — Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work? — HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work — Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis — HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis — Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says — HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk — Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials — HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials — Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care — HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons — Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons — HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons — Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists — HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists — Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared — HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared — Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research — HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research — Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md
- tavapadon-new-parkinsons-drug-2026 — HTML: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026 — Markdown: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026.md
- state-of-parkinsons-clinical-trials — HTML: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials.md
- where-parkinsons-clinical-trials-happen — HTML: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen — Markdown: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen.md

## PD Curated — Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). Append `.md` to any `/trial/{nctId}` URL in the sitemap to reach its twin; below are the 50 most recently updated for quick discovery.

- Reduce movement and mood problems (NCT07625540) — HTML: https://parkinsonspathways.com/trial/NCT07625540 — Markdown: https://parkinsonspathways.com/trial/NCT07625540.md
- Test imaging tracer for Parkinson (NCT07617688) — HTML: https://parkinsonspathways.com/trial/NCT07617688 — Markdown: https://parkinsonspathways.com/trial/NCT07617688.md
- Reduce memory impairment using levetiracetam (NCT04643327) — HTML: https://parkinsonspathways.com/trial/NCT04643327 — Markdown: https://parkinsonspathways.com/trial/NCT04643327.md
- Identify inherited genes causing Parkinson (NCT01558479) — HTML: https://parkinsonspathways.com/trial/NCT01558479 — Markdown: https://parkinsonspathways.com/trial/NCT01558479.md
- Validate Turkish involuntary movements scale (NCT07023224) — HTML: https://parkinsonspathways.com/trial/NCT07023224 — Markdown: https://parkinsonspathways.com/trial/NCT07023224.md
- Lemborexant improves motor and sleep (NCT07384429) — HTML: https://parkinsonspathways.com/trial/NCT07384429 — Markdown: https://parkinsonspathways.com/trial/NCT07384429.md
- Compare pimavanserin and quetiapine effectiveness (NCT05590637) — HTML: https://parkinsonspathways.com/trial/NCT05590637 — Markdown: https://parkinsonspathways.com/trial/NCT05590637.md
- Reduce medication wearing off symptoms (NCT06145711) — HTML: https://parkinsonspathways.com/trial/NCT06145711 — Markdown: https://parkinsonspathways.com/trial/NCT06145711.md
- Improve recognizing emotions on medication (NCT06884722) — HTML: https://parkinsonspathways.com/trial/NCT06884722 — Markdown: https://parkinsonspathways.com/trial/NCT06884722.md
- Test new antibody slows progression (NCT06809400) — HTML: https://parkinsonspathways.com/trial/NCT06809400 — Markdown: https://parkinsonspathways.com/trial/NCT06809400.md
- Reduce tremor and movement fluctuations (NCT06909045) — HTML: https://parkinsonspathways.com/trial/NCT06909045 — Markdown: https://parkinsonspathways.com/trial/NCT06909045.md
- Improve thinking with brain stimulation (NCT06090682) — HTML: https://parkinsonspathways.com/trial/NCT06090682 — Markdown: https://parkinsonspathways.com/trial/NCT06090682.md
- Restore glucocerebrosidase activity in putamen (NCT05565443) — HTML: https://parkinsonspathways.com/trial/NCT05565443 — Markdown: https://parkinsonspathways.com/trial/NCT05565443.md
- Improve walking confidence through imagery (NCT07193355) — HTML: https://parkinsonspathways.com/trial/NCT07193355 — Markdown: https://parkinsonspathways.com/trial/NCT07193355.md
- Detect early loss of dopamine (NCT06456684) — HTML: https://parkinsonspathways.com/trial/NCT06456684 — Markdown: https://parkinsonspathways.com/trial/NCT06456684.md
- Provide Parkinson genetic testing results (NCT04994015) — HTML: https://parkinsonspathways.com/trial/NCT04994015 — Markdown: https://parkinsonspathways.com/trial/NCT04994015.md
- Improve walking speed and balance (NCT07378722) — HTML: https://parkinsonspathways.com/trial/NCT07378722 — Markdown: https://parkinsonspathways.com/trial/NCT07378722.md
- Reduce tremor through neurosurgical evaluation (NCT00060541) — HTML: https://parkinsonspathways.com/trial/NCT00060541 — Markdown: https://parkinsonspathways.com/trial/NCT00060541.md
- Brain scans track Parkinson progression (NCT05516719) — HTML: https://parkinsonspathways.com/trial/NCT05516719 — Markdown: https://parkinsonspathways.com/trial/NCT05516719.md
- Reduce tremor while preserving speech (NCT04650932) — HTML: https://parkinsonspathways.com/trial/NCT04650932 — Markdown: https://parkinsonspathways.com/trial/NCT04650932.md
- Improve cognition through caudate stimulation (NCT04715984) — HTML: https://parkinsonspathways.com/trial/NCT04715984 — Markdown: https://parkinsonspathways.com/trial/NCT04715984.md
- Driving simulator improves driving safety (NCT06320639) — HTML: https://parkinsonspathways.com/trial/NCT06320639 — Markdown: https://parkinsonspathways.com/trial/NCT06320639.md
- Improve walking with Parkinson medication (NCT02994719) — HTML: https://parkinsonspathways.com/trial/NCT02994719 — Markdown: https://parkinsonspathways.com/trial/NCT02994719.md
- Numbing surgical area speeds recovery (NCT07176494) — HTML: https://parkinsonspathways.com/trial/NCT07176494 — Markdown: https://parkinsonspathways.com/trial/NCT07176494.md
- New drug slows Parkinson progression (NCT06732180) — HTML: https://parkinsonspathways.com/trial/NCT06732180 — Markdown: https://parkinsonspathways.com/trial/NCT06732180.md
- Improve walking balance and thinking (NCT06868160) — HTML: https://parkinsonspathways.com/trial/NCT06868160 — Markdown: https://parkinsonspathways.com/trial/NCT06868160.md
- Reduce freezing episodes during walking (NCT06316232) — HTML: https://parkinsonspathways.com/trial/NCT06316232 — Markdown: https://parkinsonspathways.com/trial/NCT06316232.md
- Reduce medication wearing off fluctuations (NCT06928519) — HTML: https://parkinsonspathways.com/trial/NCT06928519 — Markdown: https://parkinsonspathways.com/trial/NCT06928519.md
- Map brain signals causing tremor (NCT06692920) — HTML: https://parkinsonspathways.com/trial/NCT06692920 — Markdown: https://parkinsonspathways.com/trial/NCT06692920.md
- Determine cancer risk in Parkinson (NCT06814431) — HTML: https://parkinsonspathways.com/trial/NCT06814431 — Markdown: https://parkinsonspathways.com/trial/NCT06814431.md
- Improve walking with mixed reality (NCT06459154) — HTML: https://parkinsonspathways.com/trial/NCT06459154 — Markdown: https://parkinsonspathways.com/trial/NCT06459154.md
- Reduce upper limb tremor severity (NCT04501133) — HTML: https://parkinsonspathways.com/trial/NCT04501133 — Markdown: https://parkinsonspathways.com/trial/NCT04501133.md
- Prevent mania after brain stimulation (NCT05444907) — HTML: https://parkinsonspathways.com/trial/NCT05444907 — Markdown: https://parkinsonspathways.com/trial/NCT05444907.md
- Improve gait through smartphone training (NCT07380737) — HTML: https://parkinsonspathways.com/trial/NCT07380737 — Markdown: https://parkinsonspathways.com/trial/NCT07380737.md
- Improve gait stability using cane (NCT06950255) — HTML: https://parkinsonspathways.com/trial/NCT06950255 — Markdown: https://parkinsonspathways.com/trial/NCT06950255.md
- Improve walking through Amazonian dance (NCT06967493) — HTML: https://parkinsonspathways.com/trial/NCT06967493 — Markdown: https://parkinsonspathways.com/trial/NCT06967493.md
- Improve cognition through aerobic exercise (NCT07299279) — HTML: https://parkinsonspathways.com/trial/NCT07299279 — Markdown: https://parkinsonspathways.com/trial/NCT07299279.md
- Home neck stimulation improves walking (NCT06562569) — HTML: https://parkinsonspathways.com/trial/NCT06562569 — Markdown: https://parkinsonspathways.com/trial/NCT06562569.md
- Image brain alpha synuclein deposition (NCT07348250) — HTML: https://parkinsonspathways.com/trial/NCT07348250 — Markdown: https://parkinsonspathways.com/trial/NCT07348250.md
- Improve gait with Cionic Sleeve (NCT07284823) — HTML: https://parkinsonspathways.com/trial/NCT07284823 — Markdown: https://parkinsonspathways.com/trial/NCT07284823.md
- Early detection slows Parkinson progression (NCT07467460) — HTML: https://parkinsonspathways.com/trial/NCT07467460 — Markdown: https://parkinsonspathways.com/trial/NCT07467460.md
- Transplant restores dopamine producing cells (NCT06482268) — HTML: https://parkinsonspathways.com/trial/NCT06482268 — Markdown: https://parkinsonspathways.com/trial/NCT06482268.md
- Relate genetic changes to mood (NCT05518617) — HTML: https://parkinsonspathways.com/trial/NCT05518617 — Markdown: https://parkinsonspathways.com/trial/NCT05518617.md
- Mediterranean diet slows Parkinson progression (NCT06705517) — HTML: https://parkinsonspathways.com/trial/NCT06705517 — Markdown: https://parkinsonspathways.com/trial/NCT06705517.md
- Predict treatment response from genetics (NCT03523052) — HTML: https://parkinsonspathways.com/trial/NCT03523052 — Markdown: https://parkinsonspathways.com/trial/NCT03523052.md
- Gentle ear stimulation improves movement (NCT06409338) — HTML: https://parkinsonspathways.com/trial/NCT06409338 — Markdown: https://parkinsonspathways.com/trial/NCT06409338.md
- Strengthen cough to reduce aspiration (NCT05700825) — HTML: https://parkinsonspathways.com/trial/NCT05700825 — Markdown: https://parkinsonspathways.com/trial/NCT05700825.md
- Tenofovir slows Parkinson disease progression (NCT06356662) — HTML: https://parkinsonspathways.com/trial/NCT06356662 — Markdown: https://parkinsonspathways.com/trial/NCT06356662.md
- Improve ability to stop actions (NCT07022522) — HTML: https://parkinsonspathways.com/trial/NCT07022522 — Markdown: https://parkinsonspathways.com/trial/NCT07022522.md
- Improve inspiratory strength and fitness (NCT07010783) — HTML: https://parkinsonspathways.com/trial/NCT07010783 — Markdown: https://parkinsonspathways.com/trial/NCT07010783.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only — no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml) — clean HTML URLs for every public page (only `/trial/{nctId}`, `/learn/{slug}`, `/trials-near-me`, `/trials-near-me/{city}`, `/trials/{type}/{slug}`, and `/trials/eu/{euctId}` entries support a `.md` twin)
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml) — references the main sitemap
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)