# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 508 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated**: Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror**: A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Selected content families expose clean Markdown twins (append `.md` to the URL) with YAML frontmatter, intended for LLM ingestion. Supported patterns: `/learn/{slug}.md`, `/caregivers.md`, `/caregivers/{slug}.md`, `/trial/{nctId}.md`, `/trials-near-me.md`, `/trials-near-me/{city}.md`, `/trials/{type}/{slug}.md`. Pages such as `/`, `/about`, `/trials`, `/insights`, `/match`, and `/digest` do not have Markdown twins.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 508 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Trial Outcomes & Results Tracker](https://parkinsonspathways.com/results): Completed, terminated, and withdrawn Parkinson's trials, with results and publications as they become available (Markdown twin at https://parkinsonspathways.com/results.md).
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [For Caregivers](https://parkinsonspathways.com/caregivers): Family-first guides for Parkinson's caregivers, medication routines, burnout, legal and financial paperwork, and the care partner's role in clinical trials.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.
- [Privacy Policy](https://parkinsonspathways.com/privacy): What data we collect, how we use it, and how to delete your account and all of your data. We never sell your information or share it with trial sponsors or advertisers; the only outside services we use are the technical providers needed to run the site (such as email delivery).

## PD Curated: Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways, HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways, Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean?, HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean, Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean?, HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean, Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last?, HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last, Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials, HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials, Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- How to Spot a Questionable Clinical Trial, HTML: https://parkinsonspathways.com/learn/how-to-spot-a-questionable-clinical-trial, Markdown: https://parkinsonspathways.com/learn/how-to-spot-a-questionable-clinical-trial.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials, HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials, Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know, HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons, Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo?, HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo, Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- what-the-world-is-doing-about-parkinsons, HTML: https://parkinsonspathways.com/learn/what-the-world-is-doing-about-parkinsons, Markdown: https://parkinsonspathways.com/learn/what-the-world-is-doing-about-parkinsons.md
- How Close Is a Cure for Parkinson's Disease?, HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons, Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know, HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials, Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work?, HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work, Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis, HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis, Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says, HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk, Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways, HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways, Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials, HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials, Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials, HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials, Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials, HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials, Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials, HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials, Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care, HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons, Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons, HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons, Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa, HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa, Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor, HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor, Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists, HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists, Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared, HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared, Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research, HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research, Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md
- tavapadon-new-parkinsons-drug-2026, HTML: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026, Markdown: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026.md
- state-of-parkinsons-clinical-trials, HTML: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials, Markdown: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials.md
- where-parkinsons-clinical-trials-happen, HTML: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen, Markdown: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen.md

## PD Curated: Caregiver Guides (Markdown twins)

Family-first guides for Parkinson's caregivers, available as both HTML (for humans) and Markdown (for LLM ingestion).

- The First Things to Do When You Become a Caregiver, HTML: https://parkinsonspathways.com/caregivers/first-things-to-do-when-you-become-a-caregiver, Markdown: https://parkinsonspathways.com/caregivers/first-things-to-do-when-you-become-a-caregiver.md
- Building Your Person's Care Team, HTML: https://parkinsonspathways.com/caregivers/building-your-persons-care-team, Markdown: https://parkinsonspathways.com/caregivers/building-your-persons-care-team.md
- Talking to Kids About a Parent's or Grandparent's Parkinson's, HTML: https://parkinsonspathways.com/caregivers/talking-to-kids-about-a-parents-parkinsons, Markdown: https://parkinsonspathways.com/caregivers/talking-to-kids-about-a-parents-parkinsons.md
- Anticipatory Grief: Mourning Someone Who Is Still Here, HTML: https://parkinsonspathways.com/caregivers/anticipatory-grief-parkinsons-caregiver, Markdown: https://parkinsonspathways.com/caregivers/anticipatory-grief-parkinsons-caregiver.md
- Managing Medication Schedules When Timing Actually Matters, HTML: https://parkinsonspathways.com/caregivers/managing-medication-schedules-parkinsons, Markdown: https://parkinsonspathways.com/caregivers/managing-medication-schedules-parkinsons.md
- Caregiver Burnout Is Not a Character Flaw, HTML: https://parkinsonspathways.com/caregivers/caregiver-burnout-is-not-a-character-flaw, Markdown: https://parkinsonspathways.com/caregivers/caregiver-burnout-is-not-a-character-flaw.md
- Power of Attorney and Advance Directives: Do It Now, Not Later, HTML: https://parkinsonspathways.com/caregivers/power-of-attorney-and-advance-directives-parkinsons, Markdown: https://parkinsonspathways.com/caregivers/power-of-attorney-and-advance-directives-parkinsons.md
- When Your Person Can't Consent: Legal and Ethical Considerations for Trial Enrollment, HTML: https://parkinsonspathways.com/caregivers/when-your-person-cant-consent-clinical-trial-enrollment, Markdown: https://parkinsonspathways.com/caregivers/when-your-person-cant-consent-clinical-trial-enrollment.md
- Your Role During a Clinical Trial: What to Expect as the Care Partner, HTML: https://parkinsonspathways.com/caregivers/your-role-during-a-clinical-trial-care-partner, Markdown: https://parkinsonspathways.com/caregivers/your-role-during-a-clinical-trial-care-partner.md

## PD Curated: Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). Append `.md` to any `/trial/{nctId}` URL in the sitemap to reach its twin; below are the 50 most recently updated for quick discovery.

- Ear stimulation improves walking speed (NCT07337226), HTML: https://parkinsonspathways.com/trial/NCT07337226, Markdown: https://parkinsonspathways.com/trial/NCT07337226.md
- Build breathing muscles and balance (NCT07680725), HTML: https://parkinsonspathways.com/trial/NCT07680725, Markdown: https://parkinsonspathways.com/trial/NCT07680725.md
- Map dopamine signals for mood (NCT07402928), HTML: https://parkinsonspathways.com/trial/NCT07402928, Markdown: https://parkinsonspathways.com/trial/NCT07402928.md
- Reduce tremor and movement stiffness (NCT07572903), HTML: https://parkinsonspathways.com/trial/NCT07572903, Markdown: https://parkinsonspathways.com/trial/NCT07572903.md
- Predict impulse control from scans (NCT07213219), HTML: https://parkinsonspathways.com/trial/NCT07213219, Markdown: https://parkinsonspathways.com/trial/NCT07213219.md
- Replace lost movement brain cells (NCT06167681), HTML: https://parkinsonspathways.com/trial/NCT06167681, Markdown: https://parkinsonspathways.com/trial/NCT06167681.md
- Blood test tracks Parkinson progression (NCT06941012), HTML: https://parkinsonspathways.com/trial/NCT06941012, Markdown: https://parkinsonspathways.com/trial/NCT06941012.md
- Reduce medication wearing off fluctuations (NCT06928519), HTML: https://parkinsonspathways.com/trial/NCT06928519, Markdown: https://parkinsonspathways.com/trial/NCT06928519.md
- Reduce gait freezing with cueing (NCT06733077), HTML: https://parkinsonspathways.com/trial/NCT06733077, Markdown: https://parkinsonspathways.com/trial/NCT06733077.md
- Testing new Parkinson treatment approach (NCT07488351), HTML: https://parkinsonspathways.com/trial/NCT07488351, Markdown: https://parkinsonspathways.com/trial/NCT07488351.md
- Reduce pain and autonomic symptoms (NCT05748028), HTML: https://parkinsonspathways.com/trial/NCT05748028, Markdown: https://parkinsonspathways.com/trial/NCT05748028.md
- Test biophoton therapy for tremor (NCT06147999), HTML: https://parkinsonspathways.com/trial/NCT06147999, Markdown: https://parkinsonspathways.com/trial/NCT06147999.md
- Cell transplant improves movement symptoms (NCT07572071), HTML: https://parkinsonspathways.com/trial/NCT07572071, Markdown: https://parkinsonspathways.com/trial/NCT07572071.md
- Reduce tremor using brain stimulation (NCT05752656), HTML: https://parkinsonspathways.com/trial/NCT05752656, Markdown: https://parkinsonspathways.com/trial/NCT05752656.md
- Help slow Parkinson disease progression (NCT04888364), HTML: https://parkinsonspathways.com/trial/NCT04888364, Markdown: https://parkinsonspathways.com/trial/NCT04888364.md
- Identify modifiable factors slowing progression (NCT02194816), HTML: https://parkinsonspathways.com/trial/NCT02194816, Markdown: https://parkinsonspathways.com/trial/NCT02194816.md
- Reduce constipation in Parkinson patients (NCT07310264), HTML: https://parkinsonspathways.com/trial/NCT07310264, Markdown: https://parkinsonspathways.com/trial/NCT07310264.md
- Stem cell surgery improves walking (NCT07106021), HTML: https://parkinsonspathways.com/trial/NCT07106021, Markdown: https://parkinsonspathways.com/trial/NCT07106021.md
- Reduce motor and nonmotor symptoms (NCT06548256), HTML: https://parkinsonspathways.com/trial/NCT06548256, Markdown: https://parkinsonspathways.com/trial/NCT06548256.md
- Reduce constipation using dietitian guidance (NCT07213856), HTML: https://parkinsonspathways.com/trial/NCT07213856, Markdown: https://parkinsonspathways.com/trial/NCT07213856.md
- Delay and reduce involuntary movements (NCT06570824), HTML: https://parkinsonspathways.com/trial/NCT06570824, Markdown: https://parkinsonspathways.com/trial/NCT06570824.md
- Reduce memory impairment using levetiracetam (NCT04643327), HTML: https://parkinsonspathways.com/trial/NCT04643327, Markdown: https://parkinsonspathways.com/trial/NCT04643327.md
- Improve walking speed and balance (NCT07589296), HTML: https://parkinsonspathways.com/trial/NCT07589296, Markdown: https://parkinsonspathways.com/trial/NCT07589296.md
- Improve gait with C Mill (NCT07434089), HTML: https://parkinsonspathways.com/trial/NCT07434089, Markdown: https://parkinsonspathways.com/trial/NCT07434089.md
- Brain scan detects immune activity (NCT05395624), HTML: https://parkinsonspathways.com/trial/NCT05395624, Markdown: https://parkinsonspathways.com/trial/NCT05395624.md
- Reduce nighttime awakenings with stimulation (NCT05070013), HTML: https://parkinsonspathways.com/trial/NCT05070013, Markdown: https://parkinsonspathways.com/trial/NCT05070013.md
- Identify signals predicting mood fluctuations (NCT07404241), HTML: https://parkinsonspathways.com/trial/NCT07404241, Markdown: https://parkinsonspathways.com/trial/NCT07404241.md
- Vibrating shoe improves walking stability (NCT06975059), HTML: https://parkinsonspathways.com/trial/NCT06975059, Markdown: https://parkinsonspathways.com/trial/NCT06975059.md
- Reduce anxiety symptoms with mirtazapine (NCT06530290), HTML: https://parkinsonspathways.com/trial/NCT06530290, Markdown: https://parkinsonspathways.com/trial/NCT06530290.md
- Spinal cord stimulation reduces freezing (NCT06798844), HTML: https://parkinsonspathways.com/trial/NCT06798844, Markdown: https://parkinsonspathways.com/trial/NCT06798844.md
- Hands on treatment improves sleep (NCT06671600), HTML: https://parkinsonspathways.com/trial/NCT06671600, Markdown: https://parkinsonspathways.com/trial/NCT06671600.md
- Assess propofol effects on brain (NCT05895019), HTML: https://parkinsonspathways.com/trial/NCT05895019, Markdown: https://parkinsonspathways.com/trial/NCT05895019.md
- Assess experimental pain in Parkinsons (NCT05981261), HTML: https://parkinsonspathways.com/trial/NCT05981261, Markdown: https://parkinsonspathways.com/trial/NCT05981261.md
- Improve walking with spinal stimulation (NCT06804642), HTML: https://parkinsonspathways.com/trial/NCT06804642, Markdown: https://parkinsonspathways.com/trial/NCT06804642.md
- Increase daily good on time (NCT07138560), HTML: https://parkinsonspathways.com/trial/NCT07138560, Markdown: https://parkinsonspathways.com/trial/NCT07138560.md
- Decrease resting hand tremor electrically (NCT06646510), HTML: https://parkinsonspathways.com/trial/NCT06646510, Markdown: https://parkinsonspathways.com/trial/NCT06646510.md
- Characterize freezing of gait episodes (NCT06519279), HTML: https://parkinsonspathways.com/trial/NCT06519279, Markdown: https://parkinsonspathways.com/trial/NCT06519279.md
- Improve obstacle crossing while walking (NCT06932679), HTML: https://parkinsonspathways.com/trial/NCT06932679, Markdown: https://parkinsonspathways.com/trial/NCT06932679.md
- Exercise improves walking and thinking (NCT07478146), HTML: https://parkinsonspathways.com/trial/NCT07478146, Markdown: https://parkinsonspathways.com/trial/NCT07478146.md
- Improve Parkinson care via telemedicine (NCT06479083), HTML: https://parkinsonspathways.com/trial/NCT06479083, Markdown: https://parkinsonspathways.com/trial/NCT06479083.md
- Alleviate gait freezing and instability (NCT06295614), HTML: https://parkinsonspathways.com/trial/NCT06295614, Markdown: https://parkinsonspathways.com/trial/NCT06295614.md
- Track movement disorder symptom progression (NCT05413291), HTML: https://parkinsonspathways.com/trial/NCT05413291, Markdown: https://parkinsonspathways.com/trial/NCT05413291.md
- Improve constipation with fecal transplant (NCT06388863), HTML: https://parkinsonspathways.com/trial/NCT06388863, Markdown: https://parkinsonspathways.com/trial/NCT06388863.md
- Ear stimulation slows Parkinson progression (NCT06665113), HTML: https://parkinsonspathways.com/trial/NCT06665113, Markdown: https://parkinsonspathways.com/trial/NCT06665113.md
- Boost Parkinson patients physical activity (NCT06962930), HTML: https://parkinsonspathways.com/trial/NCT06962930, Markdown: https://parkinsonspathways.com/trial/NCT06962930.md
- Reduce unilateral tremor with Exablate (NCT04991831), HTML: https://parkinsonspathways.com/trial/NCT04991831, Markdown: https://parkinsonspathways.com/trial/NCT04991831.md
- Improve side to side balance (NCT07568951), HTML: https://parkinsonspathways.com/trial/NCT07568951, Markdown: https://parkinsonspathways.com/trial/NCT07568951.md
- Monitor gait and tremor remotely (NCT06573762), HTML: https://parkinsonspathways.com/trial/NCT06573762, Markdown: https://parkinsonspathways.com/trial/NCT06573762.md
- Identify candidates for gene therapy (NCT06151002), HTML: https://parkinsonspathways.com/trial/NCT06151002, Markdown: https://parkinsonspathways.com/trial/NCT06151002.md
- Assess safety of Parkinson medication (NCT06809400), HTML: https://parkinsonspathways.com/trial/NCT06809400, Markdown: https://parkinsonspathways.com/trial/NCT06809400.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only, no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml), clean HTML URLs for every public page (only `/trial/{nctId}`, `/learn/{slug}`, `/trials-near-me`, `/trials-near-me/{city}`, `/trials/{type}/{slug}` entries support a `.md` twin)
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml), references the main sitemap
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)