# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 505 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated** — Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror** — A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Every public page has a clean Markdown twin at `<page-url>.md` with frontmatter, intended for LLM ingestion.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 505 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated — Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last? — HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last — Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials — HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials — Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials — HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know — HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo? — HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo — Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- How Close Is a Cure for Parkinson's Disease? — HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know — HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials — Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work? — HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work — Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis — HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis — Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says — HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk — Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials — HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials — Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care — HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons — Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons — HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons — Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists — HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists — Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared — HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared — Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research — HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research — Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md

## PD Curated — Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). The full set is in the sitemap; below are the 50 most recently updated for quick discovery.

- Improve walking speed and balance (NCT07589296) — HTML: https://parkinsonspathways.com/trial/NCT07589296 — Markdown: https://parkinsonspathways.com/trial/NCT07589296.md
- Map rescue medication dosing patterns (NCT07145190) — HTML: https://parkinsonspathways.com/trial/NCT07145190 — Markdown: https://parkinsonspathways.com/trial/NCT07145190.md
- Improve breathing with diaphragmatic stimulation (NCT04941326) — HTML: https://parkinsonspathways.com/trial/NCT04941326 — Markdown: https://parkinsonspathways.com/trial/NCT04941326.md
- Detect subtle walking changes early (NCT06907589) — HTML: https://parkinsonspathways.com/trial/NCT06907589 — Markdown: https://parkinsonspathways.com/trial/NCT06907589.md
- Vitamins lower blood homocysteine levels (NCT06772220) — HTML: https://parkinsonspathways.com/trial/NCT06772220 — Markdown: https://parkinsonspathways.com/trial/NCT06772220.md
- Diagnose Parkinsons disease with colonoscopy (NCT07204652) — HTML: https://parkinsonspathways.com/trial/NCT07204652 — Markdown: https://parkinsonspathways.com/trial/NCT07204652.md
- Improve sleep with bright light (NCT06129942) — HTML: https://parkinsonspathways.com/trial/NCT06129942 — Markdown: https://parkinsonspathways.com/trial/NCT06129942.md
- Silymarin slows Parkinson disease progression (NCT07001150) — HTML: https://parkinsonspathways.com/trial/NCT07001150 — Markdown: https://parkinsonspathways.com/trial/NCT07001150.md
- Distinguish Parkinson from related disorders (NCT07509125) — HTML: https://parkinsonspathways.com/trial/NCT07509125 — Markdown: https://parkinsonspathways.com/trial/NCT07509125.md
- Measure restless leg syndrome prevalence (NCT06684782) — HTML: https://parkinsonspathways.com/trial/NCT06684782 — Markdown: https://parkinsonspathways.com/trial/NCT06684782.md
- Improve gait stability using cane (NCT06950255) — HTML: https://parkinsonspathways.com/trial/NCT06950255 — Markdown: https://parkinsonspathways.com/trial/NCT06950255.md
- Improve deep sleep and thinking (NCT07441915) — HTML: https://parkinsonspathways.com/trial/NCT07441915 — Markdown: https://parkinsonspathways.com/trial/NCT07441915.md
- Reduce freezing with dynamic cycling (NCT05298150) — HTML: https://parkinsonspathways.com/trial/NCT05298150 — Markdown: https://parkinsonspathways.com/trial/NCT05298150.md
- Ear stimulation slows Parkinson progression (NCT06665113) — HTML: https://parkinsonspathways.com/trial/NCT06665113 — Markdown: https://parkinsonspathways.com/trial/NCT06665113.md
- Relate genetic changes to mood (NCT05518617) — HTML: https://parkinsonspathways.com/trial/NCT05518617 — Markdown: https://parkinsonspathways.com/trial/NCT05518617.md
- Prevent tremor relapse after thalamotomy (NCT07284719) — HTML: https://parkinsonspathways.com/trial/NCT07284719 — Markdown: https://parkinsonspathways.com/trial/NCT07284719.md
- Improve walking mobility using exoskeleton (NCT06028529) — HTML: https://parkinsonspathways.com/trial/NCT06028529 — Markdown: https://parkinsonspathways.com/trial/NCT06028529.md
- Slow early Parkinson disease progression (NCT06680830) — HTML: https://parkinsonspathways.com/trial/NCT06680830 — Markdown: https://parkinsonspathways.com/trial/NCT06680830.md
- Slow Parkinson progression with telmisartan (NCT07207057) — HTML: https://parkinsonspathways.com/trial/NCT07207057 — Markdown: https://parkinsonspathways.com/trial/NCT07207057.md
- Identify markers predicting Parkinson progression (NCT02305147) — HTML: https://parkinsonspathways.com/trial/NCT02305147 — Markdown: https://parkinsonspathways.com/trial/NCT02305147.md
- Retinal imaging detects early Parkinson (NCT07244640) — HTML: https://parkinsonspathways.com/trial/NCT07244640 — Markdown: https://parkinsonspathways.com/trial/NCT07244640.md
- Improve cognitive function with training (NCT06323278) — HTML: https://parkinsonspathways.com/trial/NCT06323278 — Markdown: https://parkinsonspathways.com/trial/NCT06323278.md
- Predict benefit from brain stimulation (NCT07376278) — HTML: https://parkinsonspathways.com/trial/NCT07376278 — Markdown: https://parkinsonspathways.com/trial/NCT07376278.md
- Brain stimulation reduces impulsive choices (NCT06485986) — HTML: https://parkinsonspathways.com/trial/NCT06485986 — Markdown: https://parkinsonspathways.com/trial/NCT06485986.md
- Aerobic exercise slows Parkinson progression (NCT05854524) — HTML: https://parkinsonspathways.com/trial/NCT05854524 — Markdown: https://parkinsonspathways.com/trial/NCT05854524.md
- Improve walking reduce caregiver burden (NCT06892717) — HTML: https://parkinsonspathways.com/trial/NCT06892717 — Markdown: https://parkinsonspathways.com/trial/NCT06892717.md
- Improve walking balance via aquatherapy (NCT07390825) — HTML: https://parkinsonspathways.com/trial/NCT07390825 — Markdown: https://parkinsonspathways.com/trial/NCT07390825.md
- Brain stimulation improves stopping movements (NCT04061135) — HTML: https://parkinsonspathways.com/trial/NCT04061135 — Markdown: https://parkinsonspathways.com/trial/NCT04061135.md
- Accurately diagnose Lewy body dementia (NCT06120049) — HTML: https://parkinsonspathways.com/trial/NCT06120049 — Markdown: https://parkinsonspathways.com/trial/NCT06120049.md
- Brain stimulation effects on thinking (NCT06329726) — HTML: https://parkinsonspathways.com/trial/NCT06329726 — Markdown: https://parkinsonspathways.com/trial/NCT06329726.md
- Reduce falls by improving balance (NCT06508801) — HTML: https://parkinsonspathways.com/trial/NCT06508801 — Markdown: https://parkinsonspathways.com/trial/NCT06508801.md
- Improve walking and reduce stiffness (NCT07572071) — HTML: https://parkinsonspathways.com/trial/NCT07572071 — Markdown: https://parkinsonspathways.com/trial/NCT07572071.md
- Reduce tremor and movement fluctuations (NCT06909045) — HTML: https://parkinsonspathways.com/trial/NCT06909045 — Markdown: https://parkinsonspathways.com/trial/NCT06909045.md
- Improve walking through Amazonian dance (NCT06967493) — HTML: https://parkinsonspathways.com/trial/NCT06967493 — Markdown: https://parkinsonspathways.com/trial/NCT06967493.md
- Improve walking speed and stability (NCT07105787) — HTML: https://parkinsonspathways.com/trial/NCT07105787 — Markdown: https://parkinsonspathways.com/trial/NCT07105787.md
- Reduce tremor using brain stimulation (NCT07574164) — HTML: https://parkinsonspathways.com/trial/NCT07574164 — Markdown: https://parkinsonspathways.com/trial/NCT07574164.md
- Reduce apathy through vagus stimulation (NCT07118956) — HTML: https://parkinsonspathways.com/trial/NCT07118956 — Markdown: https://parkinsonspathways.com/trial/NCT07118956.md
- Improve speech loudness and clarity (NCT06416553) — HTML: https://parkinsonspathways.com/trial/NCT06416553 — Markdown: https://parkinsonspathways.com/trial/NCT06416553.md
- Eye imaging detects Parkinson changes (NCT03233646) — HTML: https://parkinsonspathways.com/trial/NCT03233646 — Markdown: https://parkinsonspathways.com/trial/NCT03233646.md
- Brain stimulation reduces disabling tremor (NCT02119611) — HTML: https://parkinsonspathways.com/trial/NCT02119611 — Markdown: https://parkinsonspathways.com/trial/NCT02119611.md
- Rehabilitation measures meaningful daily improvements (NCT06487364) — HTML: https://parkinsonspathways.com/trial/NCT06487364 — Markdown: https://parkinsonspathways.com/trial/NCT06487364.md
- Test new antibody slows progression (NCT06809400) — HTML: https://parkinsonspathways.com/trial/NCT06809400 — Markdown: https://parkinsonspathways.com/trial/NCT06809400.md
- Mediterranean diet slows Parkinson progression (NCT06207136) — HTML: https://parkinsonspathways.com/trial/NCT06207136 — Markdown: https://parkinsonspathways.com/trial/NCT06207136.md
- Improve motor and cognitive function (NCT07271927) — HTML: https://parkinsonspathways.com/trial/NCT07271927 — Markdown: https://parkinsonspathways.com/trial/NCT07271927.md
- Strengthen cough to reduce aspiration (NCT05700825) — HTML: https://parkinsonspathways.com/trial/NCT05700825 — Markdown: https://parkinsonspathways.com/trial/NCT05700825.md
- Assess online reaching motor control (NCT04616508) — HTML: https://parkinsonspathways.com/trial/NCT04616508 — Markdown: https://parkinsonspathways.com/trial/NCT04616508.md
- Cell implant reduces off time (NCT06687837) — HTML: https://parkinsonspathways.com/trial/NCT06687837 — Markdown: https://parkinsonspathways.com/trial/NCT06687837.md
- Improve walking while dual tasking (NCT06416722) — HTML: https://parkinsonspathways.com/trial/NCT06416722 — Markdown: https://parkinsonspathways.com/trial/NCT06416722.md
- Reduce Parkinson fatigue through exercise (NCT06324422) — HTML: https://parkinsonspathways.com/trial/NCT06324422 — Markdown: https://parkinsonspathways.com/trial/NCT06324422.md
- Validate wearable assessment of walking (NCT05874739) — HTML: https://parkinsonspathways.com/trial/NCT05874739 — Markdown: https://parkinsonspathways.com/trial/NCT05874739.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only — no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml) — includes Learn and PD-trial Markdown twins
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml) — references the main sitemap plus paginated child sitemaps for every universal-mirror Markdown URL
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)