# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 502 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated**: Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror**: A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Selected content families expose clean Markdown twins (append `.md` to the URL) with YAML frontmatter, intended for LLM ingestion. Supported patterns: `/learn/{slug}.md`, `/caregivers.md`, `/caregivers/{slug}.md`, `/trial/{nctId}.md`, `/trials-near-me.md`, `/trials-near-me/{city}.md`, `/trials/{type}/{slug}.md`. Pages such as `/`, `/about`, `/trials`, `/insights`, `/match`, and `/digest` do not have Markdown twins.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 502 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Trial Outcomes & Results Tracker](https://parkinsonspathways.com/results): Completed, terminated, and withdrawn Parkinson's trials, with results and publications as they become available (Markdown twin at https://parkinsonspathways.com/results.md).
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [For Caregivers](https://parkinsonspathways.com/caregivers): Family-first guides for Parkinson's caregivers, medication routines, burnout, legal and financial paperwork, and the care partner's role in clinical trials.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated: Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways, HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways, Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean?, HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean, Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean?, HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean, Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last?, HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last, Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials, HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials, Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- How to Spot a Questionable Clinical Trial, HTML: https://parkinsonspathways.com/learn/how-to-spot-a-questionable-clinical-trial, Markdown: https://parkinsonspathways.com/learn/how-to-spot-a-questionable-clinical-trial.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials, HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials, Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know, HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons, Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo?, HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo, Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- what-the-world-is-doing-about-parkinsons, HTML: https://parkinsonspathways.com/learn/what-the-world-is-doing-about-parkinsons, Markdown: https://parkinsonspathways.com/learn/what-the-world-is-doing-about-parkinsons.md
- How Close Is a Cure for Parkinson's Disease?, HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons, Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know, HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials, Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work?, HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work, Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis, HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis, Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says, HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk, Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways, HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways, Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials, HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials, Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials, HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials, Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials, HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials, Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials, HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials, Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care, HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons, Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons, HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons, Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa, HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa, Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor, HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor, Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists, HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists, Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared, HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared, Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research, HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research, Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md
- tavapadon-new-parkinsons-drug-2026, HTML: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026, Markdown: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026.md
- state-of-parkinsons-clinical-trials, HTML: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials, Markdown: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials.md
- where-parkinsons-clinical-trials-happen, HTML: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen, Markdown: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen.md

## PD Curated: Caregiver Guides (Markdown twins)

Family-first guides for Parkinson's caregivers, available as both HTML (for humans) and Markdown (for LLM ingestion).

- The First Things to Do When You Become a Caregiver, HTML: https://parkinsonspathways.com/caregivers/first-things-to-do-when-you-become-a-caregiver, Markdown: https://parkinsonspathways.com/caregivers/first-things-to-do-when-you-become-a-caregiver.md
- Building Your Person's Care Team, HTML: https://parkinsonspathways.com/caregivers/building-your-persons-care-team, Markdown: https://parkinsonspathways.com/caregivers/building-your-persons-care-team.md
- Talking to Kids About a Parent's or Grandparent's Parkinson's, HTML: https://parkinsonspathways.com/caregivers/talking-to-kids-about-a-parents-parkinsons, Markdown: https://parkinsonspathways.com/caregivers/talking-to-kids-about-a-parents-parkinsons.md
- Anticipatory Grief: Mourning Someone Who Is Still Here, HTML: https://parkinsonspathways.com/caregivers/anticipatory-grief-parkinsons-caregiver, Markdown: https://parkinsonspathways.com/caregivers/anticipatory-grief-parkinsons-caregiver.md
- Managing Medication Schedules When Timing Actually Matters, HTML: https://parkinsonspathways.com/caregivers/managing-medication-schedules-parkinsons, Markdown: https://parkinsonspathways.com/caregivers/managing-medication-schedules-parkinsons.md
- Caregiver Burnout Is Not a Character Flaw, HTML: https://parkinsonspathways.com/caregivers/caregiver-burnout-is-not-a-character-flaw, Markdown: https://parkinsonspathways.com/caregivers/caregiver-burnout-is-not-a-character-flaw.md
- Power of Attorney and Advance Directives: Do It Now, Not Later, HTML: https://parkinsonspathways.com/caregivers/power-of-attorney-and-advance-directives-parkinsons, Markdown: https://parkinsonspathways.com/caregivers/power-of-attorney-and-advance-directives-parkinsons.md
- When Your Person Can't Consent: Legal and Ethical Considerations for Trial Enrollment, HTML: https://parkinsonspathways.com/caregivers/when-your-person-cant-consent-clinical-trial-enrollment, Markdown: https://parkinsonspathways.com/caregivers/when-your-person-cant-consent-clinical-trial-enrollment.md
- Your Role During a Clinical Trial: What to Expect as the Care Partner, HTML: https://parkinsonspathways.com/caregivers/your-role-during-a-clinical-trial-care-partner, Markdown: https://parkinsonspathways.com/caregivers/your-role-during-a-clinical-trial-care-partner.md

## PD Curated: Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). Append `.md` to any `/trial/{nctId}` URL in the sitemap to reach its twin; below are the 50 most recently updated for quick discovery.

- Reduce acting out dreams nightly (NCT07682532), HTML: https://parkinsonspathways.com/trial/NCT07682532, Markdown: https://parkinsonspathways.com/trial/NCT07682532.md
- Detect Parkinson disease related lesions (NCT07685873), HTML: https://parkinsonspathways.com/trial/NCT07685873, Markdown: https://parkinsonspathways.com/trial/NCT07685873.md
- Reduce early morning movement limitations (NCT07422675), HTML: https://parkinsonspathways.com/trial/NCT07422675, Markdown: https://parkinsonspathways.com/trial/NCT07422675.md
- Driving simulator improves driving safety (NCT06320639), HTML: https://parkinsonspathways.com/trial/NCT06320639, Markdown: https://parkinsonspathways.com/trial/NCT06320639.md
- Stabilize heart and blood pressure (NCT07084597), HTML: https://parkinsonspathways.com/trial/NCT07084597, Markdown: https://parkinsonspathways.com/trial/NCT07084597.md
- Boost Parkinson patients physical activity (NCT06962930), HTML: https://parkinsonspathways.com/trial/NCT06962930, Markdown: https://parkinsonspathways.com/trial/NCT06962930.md
- Targeted brain stimulation reduces depression (NCT06467695), HTML: https://parkinsonspathways.com/trial/NCT06467695, Markdown: https://parkinsonspathways.com/trial/NCT06467695.md
- Improve sleep with bright light (NCT06129942), HTML: https://parkinsonspathways.com/trial/NCT06129942, Markdown: https://parkinsonspathways.com/trial/NCT06129942.md
- Reduce movement and nonmotor symptoms (NCT07625540), HTML: https://parkinsonspathways.com/trial/NCT07625540, Markdown: https://parkinsonspathways.com/trial/NCT07625540.md
- Improve walking speed and balance (NCT07381907), HTML: https://parkinsonspathways.com/trial/NCT07381907, Markdown: https://parkinsonspathways.com/trial/NCT07381907.md
- Identify serotonin abnormalities causing pain (NCT06008704), HTML: https://parkinsonspathways.com/trial/NCT06008704, Markdown: https://parkinsonspathways.com/trial/NCT06008704.md
- Preserve brain signals during surgery (NCT06543563), HTML: https://parkinsonspathways.com/trial/NCT06543563, Markdown: https://parkinsonspathways.com/trial/NCT06543563.md
- Reduce slowness stiffness and instability (NCT06383247), HTML: https://parkinsonspathways.com/trial/NCT06383247, Markdown: https://parkinsonspathways.com/trial/NCT06383247.md
- Exercise raises brain support protein (NCT06339398), HTML: https://parkinsonspathways.com/trial/NCT06339398, Markdown: https://parkinsonspathways.com/trial/NCT06339398.md
- Brain stimulation improves daily movement (NCT02071134), HTML: https://parkinsonspathways.com/trial/NCT02071134, Markdown: https://parkinsonspathways.com/trial/NCT02071134.md
- Reduce pain and autonomic symptoms (NCT05748028), HTML: https://parkinsonspathways.com/trial/NCT05748028, Markdown: https://parkinsonspathways.com/trial/NCT05748028.md
- Prevent mania after brain stimulation (NCT05444907), HTML: https://parkinsonspathways.com/trial/NCT05444907, Markdown: https://parkinsonspathways.com/trial/NCT05444907.md
- Improve gait via vagus nerve (NCT07226284), HTML: https://parkinsonspathways.com/trial/NCT07226284, Markdown: https://parkinsonspathways.com/trial/NCT07226284.md
- Reduce overactive dopamine related behaviors (NCT07151378), HTML: https://parkinsonspathways.com/trial/NCT07151378, Markdown: https://parkinsonspathways.com/trial/NCT07151378.md
- Spinal cord stimulation reduces freezing (NCT06798844), HTML: https://parkinsonspathways.com/trial/NCT06798844, Markdown: https://parkinsonspathways.com/trial/NCT06798844.md
- Improve walking and standing balance (NCT06615115), HTML: https://parkinsonspathways.com/trial/NCT06615115, Markdown: https://parkinsonspathways.com/trial/NCT06615115.md
- Optimize brain stimulation for movement (NCT06169852), HTML: https://parkinsonspathways.com/trial/NCT06169852, Markdown: https://parkinsonspathways.com/trial/NCT06169852.md
- Improve intelligibility of Parkinson speech (NCT06815263), HTML: https://parkinsonspathways.com/trial/NCT06815263, Markdown: https://parkinsonspathways.com/trial/NCT06815263.md
- Test adaptive stimulation for walking (NCT05402163), HTML: https://parkinsonspathways.com/trial/NCT05402163, Markdown: https://parkinsonspathways.com/trial/NCT05402163.md
- Test tenapanor for Parkinson constipation (NCT06460038), HTML: https://parkinsonspathways.com/trial/NCT06460038, Markdown: https://parkinsonspathways.com/trial/NCT06460038.md
- Brain stimulation improves thinking skills (NCT06090682), HTML: https://parkinsonspathways.com/trial/NCT06090682, Markdown: https://parkinsonspathways.com/trial/NCT06090682.md
- Test intranasal insulin and glutathione (NCT05266417), HTML: https://parkinsonspathways.com/trial/NCT05266417, Markdown: https://parkinsonspathways.com/trial/NCT05266417.md
- Reduce hallucinations without worsening movement (NCT04373317), HTML: https://parkinsonspathways.com/trial/NCT04373317, Markdown: https://parkinsonspathways.com/trial/NCT04373317.md
- Improve cognition through aerobic exercise (NCT07299279), HTML: https://parkinsonspathways.com/trial/NCT07299279, Markdown: https://parkinsonspathways.com/trial/NCT07299279.md
- Slow Parkinson degeneration using Dserine (NCT07312110), HTML: https://parkinsonspathways.com/trial/NCT07312110, Markdown: https://parkinsonspathways.com/trial/NCT07312110.md
- Improve everyday walking after training (NCT07351032), HTML: https://parkinsonspathways.com/trial/NCT07351032, Markdown: https://parkinsonspathways.com/trial/NCT07351032.md
- Improve patient mood with compassion (NCT07097298), HTML: https://parkinsonspathways.com/trial/NCT07097298, Markdown: https://parkinsonspathways.com/trial/NCT07097298.md
- Assess expiratory respiratory muscle strength (NCT07308795), HTML: https://parkinsonspathways.com/trial/NCT07308795, Markdown: https://parkinsonspathways.com/trial/NCT07308795.md
- Reduce depressive symptoms in Parkinsons (NCT06455293), HTML: https://parkinsonspathways.com/trial/NCT06455293, Markdown: https://parkinsonspathways.com/trial/NCT06455293.md
- Brain stimulation improves eye alignment (NCT05400499), HTML: https://parkinsonspathways.com/trial/NCT05400499, Markdown: https://parkinsonspathways.com/trial/NCT05400499.md
- Help slow Parkinson disease progression (NCT04888364), HTML: https://parkinsonspathways.com/trial/NCT04888364, Markdown: https://parkinsonspathways.com/trial/NCT04888364.md
- Characterize freezing of gait episodes (NCT06519279), HTML: https://parkinsonspathways.com/trial/NCT06519279, Markdown: https://parkinsonspathways.com/trial/NCT06519279.md
- Improve upper limb motor learning (NCT05960331), HTML: https://parkinsonspathways.com/trial/NCT05960331, Markdown: https://parkinsonspathways.com/trial/NCT05960331.md
- Brain controlled training improves walking (NCT06690931), HTML: https://parkinsonspathways.com/trial/NCT06690931, Markdown: https://parkinsonspathways.com/trial/NCT06690931.md
- Measure dance exercise energy expenditure (NCT06425731), HTML: https://parkinsonspathways.com/trial/NCT06425731, Markdown: https://parkinsonspathways.com/trial/NCT06425731.md
- Create personalized stem cell therapies (NCT00874783), HTML: https://parkinsonspathways.com/trial/NCT00874783, Markdown: https://parkinsonspathways.com/trial/NCT00874783.md
- Reduce camptocormia pain with stimulation (NCT06291051), HTML: https://parkinsonspathways.com/trial/NCT06291051, Markdown: https://parkinsonspathways.com/trial/NCT06291051.md
- Detect brain alpha synuclein deposits (NCT06891703), HTML: https://parkinsonspathways.com/trial/NCT06891703, Markdown: https://parkinsonspathways.com/trial/NCT06891703.md
- Reduce early Parkinsons motor symptoms (NCT06874803), HTML: https://parkinsonspathways.com/trial/NCT06874803, Markdown: https://parkinsonspathways.com/trial/NCT06874803.md
- Measure internal tremor in Parkinsons (NCT06885541), HTML: https://parkinsonspathways.com/trial/NCT06885541, Markdown: https://parkinsonspathways.com/trial/NCT06885541.md
- Improve walking while dual tasking (NCT06416722), HTML: https://parkinsonspathways.com/trial/NCT06416722, Markdown: https://parkinsonspathways.com/trial/NCT06416722.md
- Improve balance using exercise priming (NCT06133283), HTML: https://parkinsonspathways.com/trial/NCT06133283, Markdown: https://parkinsonspathways.com/trial/NCT06133283.md
- Targeted brain stimulation reduces tremor (NCT05658302), HTML: https://parkinsonspathways.com/trial/NCT05658302, Markdown: https://parkinsonspathways.com/trial/NCT05658302.md
- Reduce tremor using brain stimulation (NCT05752656), HTML: https://parkinsonspathways.com/trial/NCT05752656, Markdown: https://parkinsonspathways.com/trial/NCT05752656.md
- Restore dopamine producing brain cells (NCT07080775), HTML: https://parkinsonspathways.com/trial/NCT07080775, Markdown: https://parkinsonspathways.com/trial/NCT07080775.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only, no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml), clean HTML URLs for every public page (only `/trial/{nctId}`, `/learn/{slug}`, `/trials-near-me`, `/trials-near-me/{city}`, `/trials/{type}/{slug}` entries support a `.md` twin)
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml), references the main sitemap
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)