# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 507 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated** — Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror** — A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Every public page has a clean Markdown twin at `<page-url>.md` with frontmatter, intended for LLM ingestion.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 507 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated — Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last? — HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last — Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials — HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials — Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials — HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know — HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo? — HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo — Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- How Close Is a Cure for Parkinson's Disease? — HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know — HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials — Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work? — HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work — Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis — HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis — Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says — HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk — Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials — HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials — Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care — HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons — Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons — HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons — Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists — HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists — Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared — HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared — Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research — HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research — Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md
- tavapadon-new-parkinsons-drug-2026 — HTML: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026 — Markdown: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026.md

## PD Curated — Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). The full set is in the sitemap; below are the 50 most recently updated for quick discovery.

- Reduce medication wearing off fluctuations (NCT06928519) — HTML: https://parkinsonspathways.com/trial/NCT06928519 — Markdown: https://parkinsonspathways.com/trial/NCT06928519.md
- Improve walking using visual feedback (NCT07322939) — HTML: https://parkinsonspathways.com/trial/NCT07322939 — Markdown: https://parkinsonspathways.com/trial/NCT07322939.md
- Improve swallowing safety and function (NCT07153692) — HTML: https://parkinsonspathways.com/trial/NCT07153692 — Markdown: https://parkinsonspathways.com/trial/NCT07153692.md
- Reduce off period motor fluctuations (NCT07166757) — HTML: https://parkinsonspathways.com/trial/NCT07166757 — Markdown: https://parkinsonspathways.com/trial/NCT07166757.md
- Reduce on off motor swings (NCT05471609) — HTML: https://parkinsonspathways.com/trial/NCT05471609 — Markdown: https://parkinsonspathways.com/trial/NCT05471609.md
- Improve walking speed and balance (NCT07381907) — HTML: https://parkinsonspathways.com/trial/NCT07381907 — Markdown: https://parkinsonspathways.com/trial/NCT07381907.md
- Improve motor function using StimSearch (NCT06205043) — HTML: https://parkinsonspathways.com/trial/NCT06205043 — Markdown: https://parkinsonspathways.com/trial/NCT06205043.md
- Assess speech and swallowing function (NCT04706234) — HTML: https://parkinsonspathways.com/trial/NCT04706234 — Markdown: https://parkinsonspathways.com/trial/NCT04706234.md
- Reduce lower extremity muscle stiffness (NCT05884944) — HTML: https://parkinsonspathways.com/trial/NCT05884944 — Markdown: https://parkinsonspathways.com/trial/NCT05884944.md
- Improve constipation with fecal transplant (NCT06388863) — HTML: https://parkinsonspathways.com/trial/NCT06388863 — Markdown: https://parkinsonspathways.com/trial/NCT06388863.md
- Identify motor plasticity affecting walking (NCT05286736) — HTML: https://parkinsonspathways.com/trial/NCT05286736 — Markdown: https://parkinsonspathways.com/trial/NCT05286736.md
- Improve walking with transcranial stimulation (NCT07291687) — HTML: https://parkinsonspathways.com/trial/NCT07291687 — Markdown: https://parkinsonspathways.com/trial/NCT07291687.md
- Improve balance using Segway training (NCT05982730) — HTML: https://parkinsonspathways.com/trial/NCT05982730 — Markdown: https://parkinsonspathways.com/trial/NCT05982730.md
- Reduce depression anxiety and stress (NCT06821230) — HTML: https://parkinsonspathways.com/trial/NCT06821230 — Markdown: https://parkinsonspathways.com/trial/NCT06821230.md
- Personalized stimulation to improve walking (NCT06350617) — HTML: https://parkinsonspathways.com/trial/NCT06350617 — Markdown: https://parkinsonspathways.com/trial/NCT06350617.md
- Magnetic pulses detect thinking problems (NCT06835595) — HTML: https://parkinsonspathways.com/trial/NCT06835595 — Markdown: https://parkinsonspathways.com/trial/NCT06835595.md
- Sound waves reduce movement stiffness (NCT07207122) — HTML: https://parkinsonspathways.com/trial/NCT07207122 — Markdown: https://parkinsonspathways.com/trial/NCT07207122.md
- Improve attention during brain stimulation (NCT06899022) — HTML: https://parkinsonspathways.com/trial/NCT06899022 — Markdown: https://parkinsonspathways.com/trial/NCT06899022.md
- Assess arm endurance measurement reliability (NCT06482502) — HTML: https://parkinsonspathways.com/trial/NCT06482502 — Markdown: https://parkinsonspathways.com/trial/NCT06482502.md
- Reduce medication wearing off symptoms (NCT06145711) — HTML: https://parkinsonspathways.com/trial/NCT06145711 — Markdown: https://parkinsonspathways.com/trial/NCT06145711.md
- Reduce freezing of gait episodes (NCT05292794) — HTML: https://parkinsonspathways.com/trial/NCT05292794 — Markdown: https://parkinsonspathways.com/trial/NCT05292794.md
- Detect Parkinson related brain changes (NCT06098612) — HTML: https://parkinsonspathways.com/trial/NCT06098612 — Markdown: https://parkinsonspathways.com/trial/NCT06098612.md
- Improve walking speed and stability (NCT07105787) — HTML: https://parkinsonspathways.com/trial/NCT07105787 — Markdown: https://parkinsonspathways.com/trial/NCT07105787.md
- Magnetic stimulation reduces involuntary jerks (NCT06570824) — HTML: https://parkinsonspathways.com/trial/NCT06570824 — Markdown: https://parkinsonspathways.com/trial/NCT06570824.md
- Reduce camptocormia pain with stimulation (NCT06291051) — HTML: https://parkinsonspathways.com/trial/NCT06291051 — Markdown: https://parkinsonspathways.com/trial/NCT06291051.md
- Aerobic exercise slows Parkinson progression (NCT05854524) — HTML: https://parkinsonspathways.com/trial/NCT05854524 — Markdown: https://parkinsonspathways.com/trial/NCT05854524.md
- Predict falls by assessing balance (NCT07148700) — HTML: https://parkinsonspathways.com/trial/NCT07148700 — Markdown: https://parkinsonspathways.com/trial/NCT07148700.md
- Reduce wearing off between doses (NCT07432958) — HTML: https://parkinsonspathways.com/trial/NCT07432958 — Markdown: https://parkinsonspathways.com/trial/NCT07432958.md
- Improve walking using auditory cueing (NCT06142448) — HTML: https://parkinsonspathways.com/trial/NCT06142448 — Markdown: https://parkinsonspathways.com/trial/NCT06142448.md
- Detect serotonin loss in Parkinson (NCT05516732) — HTML: https://parkinsonspathways.com/trial/NCT05516732 — Markdown: https://parkinsonspathways.com/trial/NCT05516732.md
- Home neck stimulation improves walking (NCT06562569) — HTML: https://parkinsonspathways.com/trial/NCT06562569 — Markdown: https://parkinsonspathways.com/trial/NCT06562569.md
- Improve walking with spinal stimulation (NCT06804642) — HTML: https://parkinsonspathways.com/trial/NCT06804642 — Markdown: https://parkinsonspathways.com/trial/NCT06804642.md
- Improve posture and trunk flexibility (NCT06536478) — HTML: https://parkinsonspathways.com/trial/NCT06536478 — Markdown: https://parkinsonspathways.com/trial/NCT06536478.md
- Improve walking reduce caregiver burden (NCT06892717) — HTML: https://parkinsonspathways.com/trial/NCT06892717 — Markdown: https://parkinsonspathways.com/trial/NCT06892717.md
- Reduce tremor and involuntary movements (NCT05626608) — HTML: https://parkinsonspathways.com/trial/NCT05626608 — Markdown: https://parkinsonspathways.com/trial/NCT05626608.md
- Improve balance with motor imagery (NCT06154356) — HTML: https://parkinsonspathways.com/trial/NCT06154356 — Markdown: https://parkinsonspathways.com/trial/NCT06154356.md
- Reduce freezing episodes during walking (NCT06630702) — HTML: https://parkinsonspathways.com/trial/NCT06630702 — Markdown: https://parkinsonspathways.com/trial/NCT06630702.md
- Reduce freezing of gait remotely (NCT06957405) — HTML: https://parkinsonspathways.com/trial/NCT06957405 — Markdown: https://parkinsonspathways.com/trial/NCT06957405.md
- Improve balance through arm function (NCT06591975) — HTML: https://parkinsonspathways.com/trial/NCT06591975 — Markdown: https://parkinsonspathways.com/trial/NCT06591975.md
- Increase participation in daily activities (NCT06248073) — HTML: https://parkinsonspathways.com/trial/NCT06248073 — Markdown: https://parkinsonspathways.com/trial/NCT06248073.md
- Improve walking balance and thinking (NCT06868160) — HTML: https://parkinsonspathways.com/trial/NCT06868160 — Markdown: https://parkinsonspathways.com/trial/NCT06868160.md
- Reduce motor symptoms using synbiotic (NCT05576818) — HTML: https://parkinsonspathways.com/trial/NCT05576818 — Markdown: https://parkinsonspathways.com/trial/NCT05576818.md
- Reduce hallucinations without worsening movement (NCT04373317) — HTML: https://parkinsonspathways.com/trial/NCT04373317 — Markdown: https://parkinsonspathways.com/trial/NCT04373317.md
- Improve speech clarity with feedback (NCT06540989) — HTML: https://parkinsonspathways.com/trial/NCT06540989 — Markdown: https://parkinsonspathways.com/trial/NCT06540989.md
- Use spinal fluid to diagnose (NCT04844060) — HTML: https://parkinsonspathways.com/trial/NCT04844060 — Markdown: https://parkinsonspathways.com/trial/NCT04844060.md
- Determine side that reduces freezing (NCT06994728) — HTML: https://parkinsonspathways.com/trial/NCT06994728 — Markdown: https://parkinsonspathways.com/trial/NCT06994728.md
- Improve walking and reduce stiffness (NCT07572071) — HTML: https://parkinsonspathways.com/trial/NCT07572071 — Markdown: https://parkinsonspathways.com/trial/NCT07572071.md
- Increase walking endurance with exercise (NCT06339398) — HTML: https://parkinsonspathways.com/trial/NCT06339398 — Markdown: https://parkinsonspathways.com/trial/NCT06339398.md
- Improve balance through virtual reality (NCT07359716) — HTML: https://parkinsonspathways.com/trial/NCT07359716 — Markdown: https://parkinsonspathways.com/trial/NCT07359716.md
- Track disease progression in Parkinson (NCT07353463) — HTML: https://parkinsonspathways.com/trial/NCT07353463 — Markdown: https://parkinsonspathways.com/trial/NCT07353463.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only — no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml) — includes Learn and PD-trial Markdown twins
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml) — references the main sitemap plus paginated child sitemaps for every universal-mirror Markdown URL
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)