# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 508 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated** — Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror** — A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Every public page has a clean Markdown twin at `<page-url>.md` with frontmatter, intended for LLM ingestion.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 508 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated — Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last? — HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last — Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials — HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials — Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials — HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know — HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo? — HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo — Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- How Close Is a Cure for Parkinson's Disease? — HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know — HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials — Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work? — HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work — Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis — HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis — Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says — HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk — Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials — HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials — Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care — HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons — Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons — HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons — Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists — HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists — Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared — HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared — Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research — HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research — Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md

## PD Curated — Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). The full set is in the sitemap; below are the 50 most recently updated for quick discovery.

- Improve speech volume with amplification (NCT07599696) — HTML: https://parkinsonspathways.com/trial/NCT07599696 — Markdown: https://parkinsonspathways.com/trial/NCT07599696.md
- Separate Parkinson from similar disorders (NCT06490926) — HTML: https://parkinsonspathways.com/trial/NCT06490926 — Markdown: https://parkinsonspathways.com/trial/NCT06490926.md
- Predict Parkinson or dementia risk (NCT06629207) — HTML: https://parkinsonspathways.com/trial/NCT06629207 — Markdown: https://parkinsonspathways.com/trial/NCT06629207.md
- Reduce cognitive decline through exercise (NCT07324330) — HTML: https://parkinsonspathways.com/trial/NCT07324330 — Markdown: https://parkinsonspathways.com/trial/NCT07324330.md
- Reduce tremor and movement fluctuations (NCT06909045) — HTML: https://parkinsonspathways.com/trial/NCT06909045 — Markdown: https://parkinsonspathways.com/trial/NCT06909045.md
- Alpha synuclein detects early Parkinson (NCT06232772) — HTML: https://parkinsonspathways.com/trial/NCT06232772 — Markdown: https://parkinsonspathways.com/trial/NCT06232772.md
- Smooth motor and behavioral fluctuations (NCT07151378) — HTML: https://parkinsonspathways.com/trial/NCT07151378 — Markdown: https://parkinsonspathways.com/trial/NCT07151378.md
- Improve walking endurance through exercise (NCT07221266) — HTML: https://parkinsonspathways.com/trial/NCT07221266 — Markdown: https://parkinsonspathways.com/trial/NCT07221266.md
- Continuous infusion reduces wearing off (NCT06965374) — HTML: https://parkinsonspathways.com/trial/NCT06965374 — Markdown: https://parkinsonspathways.com/trial/NCT06965374.md
- Self managed exercise improves walking (NCT07302386) — HTML: https://parkinsonspathways.com/trial/NCT07302386 — Markdown: https://parkinsonspathways.com/trial/NCT07302386.md
- Vibrating shoe improves walking stability (NCT06975059) — HTML: https://parkinsonspathways.com/trial/NCT06975059 — Markdown: https://parkinsonspathways.com/trial/NCT06975059.md
- Improve sleep quality through exercise (NCT05644327) — HTML: https://parkinsonspathways.com/trial/NCT05644327 — Markdown: https://parkinsonspathways.com/trial/NCT05644327.md
- Reduce medication refractory motor complications (NCT05539196) — HTML: https://parkinsonspathways.com/trial/NCT05539196 — Markdown: https://parkinsonspathways.com/trial/NCT05539196.md
- Reduce predictable wearing off periods (NCT06765668) — HTML: https://parkinsonspathways.com/trial/NCT06765668 — Markdown: https://parkinsonspathways.com/trial/NCT06765668.md
- Monitor gait and tremor remotely (NCT06573762) — HTML: https://parkinsonspathways.com/trial/NCT06573762 — Markdown: https://parkinsonspathways.com/trial/NCT06573762.md
- Improve walking while dual tasking (NCT06416722) — HTML: https://parkinsonspathways.com/trial/NCT06416722 — Markdown: https://parkinsonspathways.com/trial/NCT06416722.md
- Reduce tremor through neurosurgical evaluation (NCT00060541) — HTML: https://parkinsonspathways.com/trial/NCT00060541 — Markdown: https://parkinsonspathways.com/trial/NCT00060541.md
- Boost brain energetics using exercise (NCT04426786) — HTML: https://parkinsonspathways.com/trial/NCT04426786 — Markdown: https://parkinsonspathways.com/trial/NCT04426786.md
- Restore dopamine to improve movement (NCT06753331) — HTML: https://parkinsonspathways.com/trial/NCT06753331 — Markdown: https://parkinsonspathways.com/trial/NCT06753331.md
- Detect neck norepinephrine nerve loss (NCT05741151) — HTML: https://parkinsonspathways.com/trial/NCT05741151 — Markdown: https://parkinsonspathways.com/trial/NCT05741151.md
- Identify motor plasticity affecting walking (NCT05286736) — HTML: https://parkinsonspathways.com/trial/NCT05286736 — Markdown: https://parkinsonspathways.com/trial/NCT05286736.md
- Vitamin D normalizes brain waves (NCT07096336) — HTML: https://parkinsonspathways.com/trial/NCT07096336 — Markdown: https://parkinsonspathways.com/trial/NCT07096336.md
- Compare pimavanserin and quetiapine effectiveness (NCT05590637) — HTML: https://parkinsonspathways.com/trial/NCT05590637 — Markdown: https://parkinsonspathways.com/trial/NCT05590637.md
- Alleviate gait freezing and instability (NCT06295614) — HTML: https://parkinsonspathways.com/trial/NCT06295614 — Markdown: https://parkinsonspathways.com/trial/NCT06295614.md
- Reduce depression anxiety and stress (NCT06821230) — HTML: https://parkinsonspathways.com/trial/NCT06821230 — Markdown: https://parkinsonspathways.com/trial/NCT06821230.md
- Enable new Parkinson treatment development (NCT06203106) — HTML: https://parkinsonspathways.com/trial/NCT06203106 — Markdown: https://parkinsonspathways.com/trial/NCT06203106.md
- New medication slows Parkinson progression (NCT06976268) — HTML: https://parkinsonspathways.com/trial/NCT06976268 — Markdown: https://parkinsonspathways.com/trial/NCT06976268.md
- Improve gait stability using cane (NCT06950255) — HTML: https://parkinsonspathways.com/trial/NCT06950255 — Markdown: https://parkinsonspathways.com/trial/NCT06950255.md
- Test tenapanor for Parkinson constipation (NCT06460038) — HTML: https://parkinsonspathways.com/trial/NCT06460038 — Markdown: https://parkinsonspathways.com/trial/NCT06460038.md
- Improve speech clarity and walking (NCT07588191) — HTML: https://parkinsonspathways.com/trial/NCT07588191 — Markdown: https://parkinsonspathways.com/trial/NCT07588191.md
- New medication slows early progression (NCT07174310) — HTML: https://parkinsonspathways.com/trial/NCT07174310 — Markdown: https://parkinsonspathways.com/trial/NCT07174310.md
- Personalized stimulation to improve walking (NCT06350617) — HTML: https://parkinsonspathways.com/trial/NCT06350617 — Markdown: https://parkinsonspathways.com/trial/NCT06350617.md
- Reduce drooling and improve swallowing (NCT04664634) — HTML: https://parkinsonspathways.com/trial/NCT04664634 — Markdown: https://parkinsonspathways.com/trial/NCT04664634.md
- Predict Parkinson progression using neuroimaging (NCT07024875) — HTML: https://parkinsonspathways.com/trial/NCT07024875 — Markdown: https://parkinsonspathways.com/trial/NCT07024875.md
- Assess Parkinson symptoms in Italian (NCT07316751) — HTML: https://parkinsonspathways.com/trial/NCT07316751 — Markdown: https://parkinsonspathways.com/trial/NCT07316751.md
- Reduce freezing episodes while walking (NCT06848205) — HTML: https://parkinsonspathways.com/trial/NCT06848205 — Markdown: https://parkinsonspathways.com/trial/NCT06848205.md
- Distinguish Parkinson from related disorders (NCT07509125) — HTML: https://parkinsonspathways.com/trial/NCT07509125 — Markdown: https://parkinsonspathways.com/trial/NCT07509125.md
- Cycling slows Parkinson disease progression (NCT06442033) — HTML: https://parkinsonspathways.com/trial/NCT06442033 — Markdown: https://parkinsonspathways.com/trial/NCT06442033.md
- Improve thinking with scalp stimulation (NCT05808504) — HTML: https://parkinsonspathways.com/trial/NCT05808504 — Markdown: https://parkinsonspathways.com/trial/NCT05808504.md
- Improve walking through cognitive rehabilitation (NCT06588920) — HTML: https://parkinsonspathways.com/trial/NCT06588920 — Markdown: https://parkinsonspathways.com/trial/NCT06588920.md
- Detect early loss of dopamine (NCT06456684) — HTML: https://parkinsonspathways.com/trial/NCT06456684 — Markdown: https://parkinsonspathways.com/trial/NCT06456684.md
- Identify neural causes of dysphagia (NCT07299448) — HTML: https://parkinsonspathways.com/trial/NCT07299448 — Markdown: https://parkinsonspathways.com/trial/NCT07299448.md
- Improve breathing with diaphragmatic stimulation (NCT04941326) — HTML: https://parkinsonspathways.com/trial/NCT04941326 — Markdown: https://parkinsonspathways.com/trial/NCT04941326.md
- Fast bodyweight training improves speed (NCT06646523) — HTML: https://parkinsonspathways.com/trial/NCT06646523 — Markdown: https://parkinsonspathways.com/trial/NCT06646523.md
- Find drugs boosting cell cleanup (NCT05536388) — HTML: https://parkinsonspathways.com/trial/NCT05536388 — Markdown: https://parkinsonspathways.com/trial/NCT05536388.md
- Improve mobility through physical activity (NCT06901869) — HTML: https://parkinsonspathways.com/trial/NCT06901869 — Markdown: https://parkinsonspathways.com/trial/NCT06901869.md
- Improve walking balance and attention (NCT06444685) — HTML: https://parkinsonspathways.com/trial/NCT06444685 — Markdown: https://parkinsonspathways.com/trial/NCT06444685.md
- Brain imaging maps protein clumps (NCT07020026) — HTML: https://parkinsonspathways.com/trial/NCT07020026 — Markdown: https://parkinsonspathways.com/trial/NCT07020026.md
- Restore dopamine production in putamen (NCT07106021) — HTML: https://parkinsonspathways.com/trial/NCT07106021 — Markdown: https://parkinsonspathways.com/trial/NCT07106021.md
- Reduce freezing episodes while walking (NCT06598878) — HTML: https://parkinsonspathways.com/trial/NCT06598878 — Markdown: https://parkinsonspathways.com/trial/NCT06598878.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only — no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml) — includes Learn and PD-trial Markdown twins
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml) — references the main sitemap plus paginated child sitemaps for every universal-mirror Markdown URL
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)