# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 509 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated**: Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror**: A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Selected content families expose clean Markdown twins (append `.md` to the URL) with YAML frontmatter, intended for LLM ingestion. Supported patterns: `/learn/{slug}.md`, `/caregivers.md`, `/caregivers/{slug}.md`, `/trial/{nctId}.md`, `/trials-near-me.md`, `/trials-near-me/{city}.md`, `/trials/{type}/{slug}.md`, `/insights.md`, `/insights/monthly/{period}.md`, `/pipeline.md`, `/pipeline/{slug}.md`, `/results.md`. Pages such as `/`, `/about`, `/trials`, `/match`, and `/digest` do not have Markdown twins.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 509 recruiting Parkinson's clinical trials by phase, study type, enrollment size, and country.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Trial Outcomes & Results Tracker](https://parkinsonspathways.com/results): Completed, terminated, and withdrawn Parkinson's trials, with results and publications as they become available (Markdown twin at https://parkinsonspathways.com/results.md).
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map (Markdown twin at https://parkinsonspathways.com/insights.md).
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [For Caregivers](https://parkinsonspathways.com/caregivers): Family-first guides for Parkinson's caregivers, medication routines, burnout, legal and financial paperwork, and the care partner's role in clinical trials.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.
- [How We Protect You](https://parkinsonspathways.com/trust): The site's trust commitments in plain words: no account needed to browse, personal details never shared with sponsors or recruiters, no data sales or ads, no payment for enrollments, trial data from ClinicalTrials.gov refreshed daily, and digest emails used only for the digest.
- [Privacy Policy](https://parkinsonspathways.com/privacy): What data we collect, how we use it, and how to delete your account and all of your data. We never sell your information or share it with trial sponsors or advertisers; the only outside services we use are the technical providers needed to run the site (such as email delivery).

## PD Curated: Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways, HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways, Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean?, HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean, Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean?, HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean, Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last?, HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last, Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials, HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials, Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- How to Spot a Questionable Clinical Trial, HTML: https://parkinsonspathways.com/learn/how-to-spot-a-questionable-clinical-trial, Markdown: https://parkinsonspathways.com/learn/how-to-spot-a-questionable-clinical-trial.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials, HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials, Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know, HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons, Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo?, HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo, Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- what-the-world-is-doing-about-parkinsons, HTML: https://parkinsonspathways.com/learn/what-the-world-is-doing-about-parkinsons, Markdown: https://parkinsonspathways.com/learn/what-the-world-is-doing-about-parkinsons.md
- How Close Is a Cure for Parkinson's Disease?, HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons, Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know, HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials, Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work?, HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work, Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis, HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis, Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says, HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk, Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways, HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways, Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials, HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials, Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials, HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials, Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials, HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials, Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials, HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials, Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care, HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons, Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons, HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons, Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa, HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa, Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor, HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor, Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists, HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists, Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared, HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared, Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research, HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research, Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md
- tavapadon-new-parkinsons-drug-2026, HTML: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026, Markdown: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026.md
- state-of-parkinsons-clinical-trials, HTML: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials, Markdown: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials.md
- where-parkinsons-clinical-trials-happen, HTML: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen, Markdown: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen.md

## PD Curated: Caregiver Guides (Markdown twins)

Family-first guides for Parkinson's caregivers, available as both HTML (for humans) and Markdown (for LLM ingestion).

- The First Things to Do When You Become a Caregiver, HTML: https://parkinsonspathways.com/caregivers/first-things-to-do-when-you-become-a-caregiver, Markdown: https://parkinsonspathways.com/caregivers/first-things-to-do-when-you-become-a-caregiver.md
- Building Your Person's Care Team, HTML: https://parkinsonspathways.com/caregivers/building-your-persons-care-team, Markdown: https://parkinsonspathways.com/caregivers/building-your-persons-care-team.md
- Talking to Kids About a Parent's or Grandparent's Parkinson's, HTML: https://parkinsonspathways.com/caregivers/talking-to-kids-about-a-parents-parkinsons, Markdown: https://parkinsonspathways.com/caregivers/talking-to-kids-about-a-parents-parkinsons.md
- Anticipatory Grief: Mourning Someone Who Is Still Here, HTML: https://parkinsonspathways.com/caregivers/anticipatory-grief-parkinsons-caregiver, Markdown: https://parkinsonspathways.com/caregivers/anticipatory-grief-parkinsons-caregiver.md
- Managing Medication Schedules When Timing Actually Matters, HTML: https://parkinsonspathways.com/caregivers/managing-medication-schedules-parkinsons, Markdown: https://parkinsonspathways.com/caregivers/managing-medication-schedules-parkinsons.md
- Caregiver Burnout Is Not a Character Flaw, HTML: https://parkinsonspathways.com/caregivers/caregiver-burnout-is-not-a-character-flaw, Markdown: https://parkinsonspathways.com/caregivers/caregiver-burnout-is-not-a-character-flaw.md
- Power of Attorney and Advance Directives: Do It Now, Not Later, HTML: https://parkinsonspathways.com/caregivers/power-of-attorney-and-advance-directives-parkinsons, Markdown: https://parkinsonspathways.com/caregivers/power-of-attorney-and-advance-directives-parkinsons.md
- When Your Person Can't Consent: Legal and Ethical Considerations for Trial Enrollment, HTML: https://parkinsonspathways.com/caregivers/when-your-person-cant-consent-clinical-trial-enrollment, Markdown: https://parkinsonspathways.com/caregivers/when-your-person-cant-consent-clinical-trial-enrollment.md
- Your Role During a Clinical Trial: What to Expect as the Care Partner, HTML: https://parkinsonspathways.com/caregivers/your-role-during-a-clinical-trial-care-partner, Markdown: https://parkinsonspathways.com/caregivers/your-role-during-a-clinical-trial-care-partner.md

## PD Curated: Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). Append `.md` to any `/trial/{nctId}` URL in the sitemap to reach its twin; below are the 50 most recently updated for quick discovery.

- Reduce hallucinations without worsening movement (NCT04373317), HTML: https://parkinsonspathways.com/trial/NCT04373317, Markdown: https://parkinsonspathways.com/trial/NCT04373317.md
- Improve thinking with brain stimulation (NCT05968703), HTML: https://parkinsonspathways.com/trial/NCT05968703, Markdown: https://parkinsonspathways.com/trial/NCT05968703.md
- Brain stimulation reduces movement slowness (NCT07397377), HTML: https://parkinsonspathways.com/trial/NCT07397377, Markdown: https://parkinsonspathways.com/trial/NCT07397377.md
- Improve upper limb motor learning (NCT05960331), HTML: https://parkinsonspathways.com/trial/NCT05960331, Markdown: https://parkinsonspathways.com/trial/NCT05960331.md
- Improve walking through transcranial stimulation (NCT07182058), HTML: https://parkinsonspathways.com/trial/NCT07182058, Markdown: https://parkinsonspathways.com/trial/NCT07182058.md
- New drug to slow Parkinson (NCT04691661), HTML: https://parkinsonspathways.com/trial/NCT04691661, Markdown: https://parkinsonspathways.com/trial/NCT04691661.md
- Reduce tremor slowness and stiffness (NCT07348705), HTML: https://parkinsonspathways.com/trial/NCT07348705, Markdown: https://parkinsonspathways.com/trial/NCT07348705.md
- Reduce apathy and boost motivation (NCT07399496), HTML: https://parkinsonspathways.com/trial/NCT07399496, Markdown: https://parkinsonspathways.com/trial/NCT07399496.md
- Measure brain tau protein buildup (NCT07020026), HTML: https://parkinsonspathways.com/trial/NCT07020026, Markdown: https://parkinsonspathways.com/trial/NCT07020026.md
- Identify serotonin abnormalities causing pain (NCT06008704), HTML: https://parkinsonspathways.com/trial/NCT06008704, Markdown: https://parkinsonspathways.com/trial/NCT06008704.md
- Optimize brain stimulation for movement (NCT06169852), HTML: https://parkinsonspathways.com/trial/NCT06169852, Markdown: https://parkinsonspathways.com/trial/NCT06169852.md
- Testing new Parkinson treatment approach (NCT07488351), HTML: https://parkinsonspathways.com/trial/NCT07488351, Markdown: https://parkinsonspathways.com/trial/NCT07488351.md
- Assess Parkinson symptoms in Italian (NCT07316751), HTML: https://parkinsonspathways.com/trial/NCT07316751, Markdown: https://parkinsonspathways.com/trial/NCT07316751.md
- Reduce freezing episodes while walking (NCT05292794), HTML: https://parkinsonspathways.com/trial/NCT05292794, Markdown: https://parkinsonspathways.com/trial/NCT05292794.md
- Can new drug ease movement (NCT06356662), HTML: https://parkinsonspathways.com/trial/NCT06356662, Markdown: https://parkinsonspathways.com/trial/NCT06356662.md
- Improve balance with motor imagery (NCT06154356), HTML: https://parkinsonspathways.com/trial/NCT06154356, Markdown: https://parkinsonspathways.com/trial/NCT06154356.md
- Rehabilitation measures meaningful daily improvements (NCT06487364), HTML: https://parkinsonspathways.com/trial/NCT06487364, Markdown: https://parkinsonspathways.com/trial/NCT06487364.md
- Improve walking confidence through imagery (NCT07193355), HTML: https://parkinsonspathways.com/trial/NCT07193355, Markdown: https://parkinsonspathways.com/trial/NCT07193355.md
- Improve walking balance with neurofeedback (NCT05800470), HTML: https://parkinsonspathways.com/trial/NCT05800470, Markdown: https://parkinsonspathways.com/trial/NCT05800470.md
- Improve recognizing emotions and movement (NCT06884722), HTML: https://parkinsonspathways.com/trial/NCT06884722, Markdown: https://parkinsonspathways.com/trial/NCT06884722.md
- Retrain driving skills using simulator (NCT03969927), HTML: https://parkinsonspathways.com/trial/NCT03969927, Markdown: https://parkinsonspathways.com/trial/NCT03969927.md
- Reduce constipation using dietitian guidance (NCT07213856), HTML: https://parkinsonspathways.com/trial/NCT07213856, Markdown: https://parkinsonspathways.com/trial/NCT07213856.md
- Reduce falls with treadmill training (NCT07058285), HTML: https://parkinsonspathways.com/trial/NCT07058285, Markdown: https://parkinsonspathways.com/trial/NCT07058285.md
- Enhance Parkinsons cognition via exercise (NCT06580977), HTML: https://parkinsonspathways.com/trial/NCT06580977, Markdown: https://parkinsonspathways.com/trial/NCT06580977.md
- Improve stopping of impulsive movements (NCT06234995), HTML: https://parkinsonspathways.com/trial/NCT06234995, Markdown: https://parkinsonspathways.com/trial/NCT06234995.md
- Build breathing muscles and balance (NCT07680725), HTML: https://parkinsonspathways.com/trial/NCT07680725, Markdown: https://parkinsonspathways.com/trial/NCT07680725.md
- Studying skin infusion for walking (NCT06916507), HTML: https://parkinsonspathways.com/trial/NCT06916507, Markdown: https://parkinsonspathways.com/trial/NCT06916507.md
- Distinguish reflexive tightness from stiffness (NCT06596187), HTML: https://parkinsonspathways.com/trial/NCT06596187, Markdown: https://parkinsonspathways.com/trial/NCT06596187.md
- Predict falls using wearable sensors (NCT06405334), HTML: https://parkinsonspathways.com/trial/NCT06405334, Markdown: https://parkinsonspathways.com/trial/NCT06405334.md
- Gene therapy to reduce stiffness (NCT07100171), HTML: https://parkinsonspathways.com/trial/NCT07100171, Markdown: https://parkinsonspathways.com/trial/NCT07100171.md
- Predict who will develop Parkinson (NCT07533799), HTML: https://parkinsonspathways.com/trial/NCT07533799, Markdown: https://parkinsonspathways.com/trial/NCT07533799.md
- Reduce depression anxiety and stress (NCT06821230), HTML: https://parkinsonspathways.com/trial/NCT06821230, Markdown: https://parkinsonspathways.com/trial/NCT06821230.md
- Improve diagnostic imaging for tremor (NCT05698810), HTML: https://parkinsonspathways.com/trial/NCT05698810, Markdown: https://parkinsonspathways.com/trial/NCT05698810.md
- Complementary medicine to reduce stiffness (NCT07207096), HTML: https://parkinsonspathways.com/trial/NCT07207096, Markdown: https://parkinsonspathways.com/trial/NCT07207096.md
- Can ear stimulation slow progression (NCT06665113), HTML: https://parkinsonspathways.com/trial/NCT06665113, Markdown: https://parkinsonspathways.com/trial/NCT06665113.md
- Test fexofenadine for motor improvement (NCT06785298), HTML: https://parkinsonspathways.com/trial/NCT06785298, Markdown: https://parkinsonspathways.com/trial/NCT06785298.md
- Prevent tremor relapse after thalamotomy (NCT07284719), HTML: https://parkinsonspathways.com/trial/NCT07284719, Markdown: https://parkinsonspathways.com/trial/NCT07284719.md
- Improve walking speed through exercise (NCT07057219), HTML: https://parkinsonspathways.com/trial/NCT07057219, Markdown: https://parkinsonspathways.com/trial/NCT07057219.md
- Identify modifiable factors slowing progression (NCT02194816), HTML: https://parkinsonspathways.com/trial/NCT02194816, Markdown: https://parkinsonspathways.com/trial/NCT02194816.md
- Check Turkish temperature sensitivity questionnaire (NCT07710625), HTML: https://parkinsonspathways.com/trial/NCT07710625, Markdown: https://parkinsonspathways.com/trial/NCT07710625.md
- Reduce predictable wearing off periods (NCT06765668), HTML: https://parkinsonspathways.com/trial/NCT06765668, Markdown: https://parkinsonspathways.com/trial/NCT06765668.md
- Collect genes to guide care (NCT04994015), HTML: https://parkinsonspathways.com/trial/NCT04994015, Markdown: https://parkinsonspathways.com/trial/NCT04994015.md
- Increase walking distance and endurance (NCT06859528), HTML: https://parkinsonspathways.com/trial/NCT06859528, Markdown: https://parkinsonspathways.com/trial/NCT06859528.md
- Reduce apathy through personalized music (NCT05505019), HTML: https://parkinsonspathways.com/trial/NCT05505019, Markdown: https://parkinsonspathways.com/trial/NCT05505019.md
- Improve hand dexterity with imagery (NCT07193303), HTML: https://parkinsonspathways.com/trial/NCT07193303, Markdown: https://parkinsonspathways.com/trial/NCT07193303.md
- Improve speech clarity with feedback (NCT06540989), HTML: https://parkinsonspathways.com/trial/NCT06540989, Markdown: https://parkinsonspathways.com/trial/NCT06540989.md
- Improve walking speed and balance (NCT07378722), HTML: https://parkinsonspathways.com/trial/NCT07378722, Markdown: https://parkinsonspathways.com/trial/NCT07378722.md
- Prevent mania after brain stimulation (NCT05444907), HTML: https://parkinsonspathways.com/trial/NCT05444907, Markdown: https://parkinsonspathways.com/trial/NCT05444907.md
- Differentiate dementias using brain imaging (NCT03019757), HTML: https://parkinsonspathways.com/trial/NCT03019757, Markdown: https://parkinsonspathways.com/trial/NCT03019757.md
- Improve access to specialist care (NCT05014971), HTML: https://parkinsonspathways.com/trial/NCT05014971, Markdown: https://parkinsonspathways.com/trial/NCT05014971.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only, no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml), clean HTML URLs for every public page (Markdown twins are not listed in the sitemap; discover them via the patterns documented in the "About" section above or via this file and https://parkinsonspathways.com/llms-full.txt)
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml), references the main sitemap
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)