# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 505 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated** — Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror** — A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Every public page has a clean Markdown twin at `<page-url>.md` with frontmatter, intended for LLM ingestion.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 505 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated — Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean? — HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean — Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last? — HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last — Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials — HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials — Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials — HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials — Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know — HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo? — HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo — Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- How Close Is a Cure for Parkinson's Disease? — HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons — Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know — HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials — Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work? — HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work — Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis — HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis — Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says — HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk — Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways — HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways — Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials — HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials — Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials — HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials — Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care — HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons — Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons — HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons — Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor — HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor — Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists — HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists — Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared — HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared — Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research — HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research — Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md

## PD Curated — Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). The full set is in the sitemap; below are the 50 most recently updated for quick discovery.

- Exoskeleton improves balance while walking (NCT07567482) — HTML: https://parkinsonspathways.com/trial/NCT07567482 — Markdown: https://parkinsonspathways.com/trial/NCT07567482.md
- Identify why physical activity declines (NCT07585409) — HTML: https://parkinsonspathways.com/trial/NCT07585409 — Markdown: https://parkinsonspathways.com/trial/NCT07585409.md
- Reduce early Parkinsons motor symptoms (NCT06874803) — HTML: https://parkinsonspathways.com/trial/NCT06874803 — Markdown: https://parkinsonspathways.com/trial/NCT06874803.md
- Reduce camptocormia pain with stimulation (NCT06291051) — HTML: https://parkinsonspathways.com/trial/NCT06291051 — Markdown: https://parkinsonspathways.com/trial/NCT06291051.md
- Assess intranasal AlloEx exosome safety (NCT05152394) — HTML: https://parkinsonspathways.com/trial/NCT05152394 — Markdown: https://parkinsonspathways.com/trial/NCT05152394.md
- Predict Parkinson progression using neuroimaging (NCT07024875) — HTML: https://parkinsonspathways.com/trial/NCT07024875 — Markdown: https://parkinsonspathways.com/trial/NCT07024875.md
- Reduce lower extremity muscle stiffness (NCT05884944) — HTML: https://parkinsonspathways.com/trial/NCT05884944 — Markdown: https://parkinsonspathways.com/trial/NCT05884944.md
- Slow Parkinson progression with glucoraphanin (NCT07360977) — HTML: https://parkinsonspathways.com/trial/NCT07360977 — Markdown: https://parkinsonspathways.com/trial/NCT07360977.md
- Genes affect medication side effects (NCT06329739) — HTML: https://parkinsonspathways.com/trial/NCT06329739 — Markdown: https://parkinsonspathways.com/trial/NCT06329739.md
- Improve daily functioning through teams (NCT05433441) — HTML: https://parkinsonspathways.com/trial/NCT05433441 — Markdown: https://parkinsonspathways.com/trial/NCT05433441.md
- Assess long term buntanetap safety (NCT07284784) — HTML: https://parkinsonspathways.com/trial/NCT07284784 — Markdown: https://parkinsonspathways.com/trial/NCT07284784.md
- Reduce anxiety and improve functioning (NCT07310147) — HTML: https://parkinsonspathways.com/trial/NCT07310147 — Markdown: https://parkinsonspathways.com/trial/NCT07310147.md
- Improve cognitive function with tributyrin (NCT07154511) — HTML: https://parkinsonspathways.com/trial/NCT07154511 — Markdown: https://parkinsonspathways.com/trial/NCT07154511.md
- Test fexofenadine for motor improvement (NCT06785298) — HTML: https://parkinsonspathways.com/trial/NCT06785298 — Markdown: https://parkinsonspathways.com/trial/NCT06785298.md
- Improve cognitive function in Parkinsons (NCT03836950) — HTML: https://parkinsonspathways.com/trial/NCT03836950 — Markdown: https://parkinsonspathways.com/trial/NCT03836950.md
- Smooth motor and behavioral fluctuations (NCT07151378) — HTML: https://parkinsonspathways.com/trial/NCT07151378 — Markdown: https://parkinsonspathways.com/trial/NCT07151378.md
- Improve balance using Segway training (NCT05982730) — HTML: https://parkinsonspathways.com/trial/NCT05982730 — Markdown: https://parkinsonspathways.com/trial/NCT05982730.md
- Reduce freezing episodes while walking (NCT07488026) — HTML: https://parkinsonspathways.com/trial/NCT07488026 — Markdown: https://parkinsonspathways.com/trial/NCT07488026.md
- Map dopamine signals for mood (NCT07402928) — HTML: https://parkinsonspathways.com/trial/NCT07402928 — Markdown: https://parkinsonspathways.com/trial/NCT07402928.md
- Increase walking distance and endurance (NCT06859528) — HTML: https://parkinsonspathways.com/trial/NCT06859528 — Markdown: https://parkinsonspathways.com/trial/NCT06859528.md
- Wearable cues reduce daily freezing (NCT06416345) — HTML: https://parkinsonspathways.com/trial/NCT06416345 — Markdown: https://parkinsonspathways.com/trial/NCT06416345.md
- Steady medication infusion improves sleep (NCT07284342) — HTML: https://parkinsonspathways.com/trial/NCT07284342 — Markdown: https://parkinsonspathways.com/trial/NCT07284342.md
- Improve gait balance and attention (NCT07465107) — HTML: https://parkinsonspathways.com/trial/NCT07465107 — Markdown: https://parkinsonspathways.com/trial/NCT07465107.md
- Improve speech clarity with feedback (NCT06540989) — HTML: https://parkinsonspathways.com/trial/NCT06540989 — Markdown: https://parkinsonspathways.com/trial/NCT06540989.md
- Reduce freezing episodes while walking (NCT06598878) — HTML: https://parkinsonspathways.com/trial/NCT06598878 — Markdown: https://parkinsonspathways.com/trial/NCT06598878.md
- Determine whether immunosuppression slows progression (NCT06834191) — HTML: https://parkinsonspathways.com/trial/NCT06834191 — Markdown: https://parkinsonspathways.com/trial/NCT06834191.md
- Increase daily steps and socialization (NCT06605183) — HTML: https://parkinsonspathways.com/trial/NCT06605183 — Markdown: https://parkinsonspathways.com/trial/NCT06605183.md
- Aerobic exercise slows Parkinson progression (NCT05854524) — HTML: https://parkinsonspathways.com/trial/NCT05854524 — Markdown: https://parkinsonspathways.com/trial/NCT05854524.md
- Improve walking with red light (NCT06916260) — HTML: https://parkinsonspathways.com/trial/NCT06916260 — Markdown: https://parkinsonspathways.com/trial/NCT06916260.md
- Distinguish Parkinson from related disorders (NCT07509125) — HTML: https://parkinsonspathways.com/trial/NCT07509125 — Markdown: https://parkinsonspathways.com/trial/NCT07509125.md
- Improve cough strength using SpiroGym (NCT06481540) — HTML: https://parkinsonspathways.com/trial/NCT06481540 — Markdown: https://parkinsonspathways.com/trial/NCT06481540.md
- Improve balance using telerehabilitation games (NCT05773885) — HTML: https://parkinsonspathways.com/trial/NCT05773885 — Markdown: https://parkinsonspathways.com/trial/NCT05773885.md
- Timed stimulation reduces hand tremor (NCT06993571) — HTML: https://parkinsonspathways.com/trial/NCT06993571 — Markdown: https://parkinsonspathways.com/trial/NCT06993571.md
- Home neck stimulation improves walking (NCT06562569) — HTML: https://parkinsonspathways.com/trial/NCT06562569 — Markdown: https://parkinsonspathways.com/trial/NCT06562569.md
- Sound waves reduce movement stiffness (NCT07207122) — HTML: https://parkinsonspathways.com/trial/NCT07207122 — Markdown: https://parkinsonspathways.com/trial/NCT07207122.md
- Individualized brain stimulation improves walking (NCT07570212) — HTML: https://parkinsonspathways.com/trial/NCT07570212 — Markdown: https://parkinsonspathways.com/trial/NCT07570212.md
- Reduce swallowing roll using rhythm (NCT06695455) — HTML: https://parkinsonspathways.com/trial/NCT06695455 — Markdown: https://parkinsonspathways.com/trial/NCT06695455.md
- Improve walking using resistance training (NCT07378813) — HTML: https://parkinsonspathways.com/trial/NCT07378813 — Markdown: https://parkinsonspathways.com/trial/NCT07378813.md
- Reduce freezing episodes while walking (NCT06506058) — HTML: https://parkinsonspathways.com/trial/NCT06506058 — Markdown: https://parkinsonspathways.com/trial/NCT06506058.md
- Reduce freezing of gait episodes (NCT05292794) — HTML: https://parkinsonspathways.com/trial/NCT05292794 — Markdown: https://parkinsonspathways.com/trial/NCT05292794.md
- Improve seated motor cognitive function (NCT06730074) — HTML: https://parkinsonspathways.com/trial/NCT06730074 — Markdown: https://parkinsonspathways.com/trial/NCT06730074.md
- Detect early loss of dopamine (NCT06456684) — HTML: https://parkinsonspathways.com/trial/NCT06456684 — Markdown: https://parkinsonspathways.com/trial/NCT06456684.md
- Predict symptoms and personalize care (NCT03523065) — HTML: https://parkinsonspathways.com/trial/NCT03523065 — Markdown: https://parkinsonspathways.com/trial/NCT03523065.md
- Improve gait and balance remotely (NCT04720365) — HTML: https://parkinsonspathways.com/trial/NCT04720365 — Markdown: https://parkinsonspathways.com/trial/NCT04720365.md
- Identify cognitive decline in Parkinsons (NCT03402919) — HTML: https://parkinsonspathways.com/trial/NCT03402919 — Markdown: https://parkinsonspathways.com/trial/NCT03402919.md
- Improve ability to stop actions (NCT07022522) — HTML: https://parkinsonspathways.com/trial/NCT07022522 — Markdown: https://parkinsonspathways.com/trial/NCT07022522.md
- Detect walking and balance problems (NCT07281794) — HTML: https://parkinsonspathways.com/trial/NCT07281794 — Markdown: https://parkinsonspathways.com/trial/NCT07281794.md
- Improve motor and cognitive function (NCT07271927) — HTML: https://parkinsonspathways.com/trial/NCT07271927 — Markdown: https://parkinsonspathways.com/trial/NCT07271927.md
- Improve hand dexterity with imagery (NCT07193303) — HTML: https://parkinsonspathways.com/trial/NCT07193303 — Markdown: https://parkinsonspathways.com/trial/NCT07193303.md
- Link brain activity to mood (NCT05820425) — HTML: https://parkinsonspathways.com/trial/NCT05820425 — Markdown: https://parkinsonspathways.com/trial/NCT05820425.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only — no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml) — includes Learn and PD-trial Markdown twins
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml) — references the main sitemap plus paginated child sitemaps for every universal-mirror Markdown URL
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)