# Parkinson's Pathways

> A free, family-friendly guide to every recruiting Parkinson's disease clinical trial. Currently tracking 507 trials.

## About

Parkinson's Pathways helps patients, caregivers, and clinicians find and understand Parkinson's clinical trials. Every trial is translated for families with a five-word goal, eligibility details, and nearby locations.

Two distinct content tiers are exposed here:

1. **PD Curated**: Parkinson's-only trials with AI-generated family-friendly summaries, five-word goals, geocoded sites, and recent site-change tracking.
2. **Universal Raw Mirror**: A larger, condition-agnostic mirror of ClinicalTrials.gov with no AI summaries and no editorial enrichment. Use this when you need source-of-truth raw data.

Selected content families expose clean Markdown twins (append `.md` to the URL) with YAML frontmatter, intended for LLM ingestion. Supported patterns: `/learn/{slug}.md`, `/caregivers.md`, `/caregivers/{slug}.md`, `/trial/{nctId}.md`, `/trials-near-me.md`, `/trials-near-me/{city}.md`, `/trials/{type}/{slug}.md`. Pages such as `/`, `/about`, `/trials`, `/insights`, `/match`, and `/digest` do not have Markdown twins.

## Key Pages

- [Browse All Trials](https://parkinsonspathways.com/trials): Search and filter all 507 recruiting Parkinson's clinical trials by phase, study type, enrollment size, country, and age eligibility.
- [Trials Near Me](https://parkinsonspathways.com/trials-near-me): Find clinical trials near a specific location using zip code or city search.
- [Trial Outcomes & Results Tracker](https://parkinsonspathways.com/results): Completed, terminated, and withdrawn Parkinson's trials, with results and publications as they become available (Markdown twin at https://parkinsonspathways.com/results.md).
- [Insights Dashboard](https://parkinsonspathways.com/insights): Visual overview of the Parkinson's trial landscape, including phase breakdown, intervention types, top sponsors, eligibility stats, and a global map.
- [Learn](https://parkinsonspathways.com/learn): Educational articles explaining clinical trial concepts, translated for families.
- [For Caregivers](https://parkinsonspathways.com/caregivers): Family-first guides for Parkinson's caregivers, medication routines, burnout, legal and financial paperwork, and the care partner's role in clinical trials.
- [About](https://parkinsonspathways.com/about): The story behind the project and how it works.

## PD Curated: Learn Articles (Markdown twins)

Each article is available as both HTML (for humans) and Markdown (for LLM ingestion). Markdown URLs include YAML frontmatter with title, description, canonical URL, and publication date.

- Why I Built Parkinson's Pathways, HTML: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways, Markdown: https://parkinsonspathways.com/learn/why-i-built-parkinsons-pathways.md
- What Do Clinical Trial Phases Mean?, HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean, Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-phases-mean.md
- What Do Clinical Trial Statuses Mean?, HTML: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean, Markdown: https://parkinsonspathways.com/learn/what-do-clinical-trial-statuses-mean.md
- How Long Does a Parkinson's Clinical Trial Last?, HTML: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last, Markdown: https://parkinsonspathways.com/learn/how-long-does-a-parkinsons-clinical-trial-last.md
- How to Talk to Your Neurologist About Clinical Trials, HTML: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials, Markdown: https://parkinsonspathways.com/learn/how-to-talk-to-your-neurologist-about-clinical-trials.md
- How to Spot a Questionable Clinical Trial, HTML: https://parkinsonspathways.com/learn/how-to-spot-a-questionable-clinical-trial, Markdown: https://parkinsonspathways.com/learn/how-to-spot-a-questionable-clinical-trial.md
- Just Diagnosed with Parkinson's? Where to Start with Clinical Trials, HTML: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials, Markdown: https://parkinsonspathways.com/learn/just-diagnosed-with-parkinsons-clinical-trials.md
- Stem Cell Therapy for Parkinson's: What You Should Actually Know, HTML: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons, Markdown: https://parkinsonspathways.com/learn/stem-cell-therapy-for-parkinsons.md
- Will My Family Member Get a Placebo?, HTML: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo, Markdown: https://parkinsonspathways.com/learn/will-my-family-member-get-a-placebo.md
- what-the-world-is-doing-about-parkinsons, HTML: https://parkinsonspathways.com/learn/what-the-world-is-doing-about-parkinsons, Markdown: https://parkinsonspathways.com/learn/what-the-world-is-doing-about-parkinsons.md
- How Close Is a Cure for Parkinson's Disease?, HTML: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons, Markdown: https://parkinsonspathways.com/learn/how-close-is-a-cure-for-parkinsons.md
- Parkinson's and Dementia: Clinical Trials Families Should Know, HTML: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials, Markdown: https://parkinsonspathways.com/learn/parkinsons-and-dementia-clinical-trials.md
- What Is Levodopa and How Does It Work?, HTML: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work, Markdown: https://parkinsonspathways.com/learn/what-is-levodopa-and-how-does-it-work.md
- What to Expect in the First Year After Diagnosis, HTML: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis, Markdown: https://parkinsonspathways.com/learn/what-to-expect-first-year-after-parkinsons-diagnosis.md
- Diet and Parkinson's Risk: What the Research Says, HTML: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk, Markdown: https://parkinsonspathways.com/learn/diet-and-parkinsons-risk.md
- ClinicalTrials.gov vs Parkinson's Pathways, HTML: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways, Markdown: https://parkinsonspathways.com/learn/clinicaltrials-gov-vs-parkinsons-pathways.md
- Interventional vs Observational Parkinson's Trials, HTML: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials, Markdown: https://parkinsonspathways.com/learn/interventional-vs-observational-parkinsons-trials.md
- Phase 1 vs Phase 2 vs Phase 3 Trials, HTML: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials, Markdown: https://parkinsonspathways.com/learn/phase-1-vs-phase-2-vs-phase-3-trials.md
- Disease-Modifying vs Symptomatic Parkinson's Trials, HTML: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials, Markdown: https://parkinsonspathways.com/learn/disease-modifying-vs-symptomatic-parkinsons-trials.md
- Industry-Sponsored vs Academic Parkinson's Trials, HTML: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials, Markdown: https://parkinsonspathways.com/learn/industry-sponsored-vs-academic-parkinsons-trials.md
- Clinical Trial vs Standard of Care, HTML: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons, Markdown: https://parkinsonspathways.com/learn/clinical-trial-vs-standard-of-care-parkinsons.md
- dbs-vs-duopa-vs-focused-ultrasound-parkinsons, HTML: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons, Markdown: https://parkinsonspathways.com/learn/dbs-vs-duopa-vs-focused-ultrasound-parkinsons.md
- parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa, HTML: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa, Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-lewy-body-dementia-vs-psp-vs-msa.md
- parkinsons-vs-essential-tremor, HTML: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor, Markdown: https://parkinsonspathways.com/learn/parkinsons-vs-essential-tremor.md
- levodopa-vs-dopamine-agonists, HTML: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists, Markdown: https://parkinsonspathways.com/learn/levodopa-vs-dopamine-agonists.md
- carbidopa-levodopa-formulations-compared, HTML: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared, Markdown: https://parkinsonspathways.com/learn/carbidopa-levodopa-formulations-compared.md
- glp1-drugs-parkinsons-research, HTML: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research, Markdown: https://parkinsonspathways.com/learn/glp1-drugs-parkinsons-research.md
- tavapadon-new-parkinsons-drug-2026, HTML: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026, Markdown: https://parkinsonspathways.com/learn/tavapadon-new-parkinsons-drug-2026.md
- state-of-parkinsons-clinical-trials, HTML: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials, Markdown: https://parkinsonspathways.com/learn/state-of-parkinsons-clinical-trials.md
- where-parkinsons-clinical-trials-happen, HTML: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen, Markdown: https://parkinsonspathways.com/learn/where-parkinsons-clinical-trials-happen.md

## PD Curated: Caregiver Guides (Markdown twins)

Family-first guides for Parkinson's caregivers, available as both HTML (for humans) and Markdown (for LLM ingestion).

- The First Things to Do When You Become a Caregiver, HTML: https://parkinsonspathways.com/caregivers/first-things-to-do-when-you-become-a-caregiver, Markdown: https://parkinsonspathways.com/caregivers/first-things-to-do-when-you-become-a-caregiver.md
- Building Your Person's Care Team, HTML: https://parkinsonspathways.com/caregivers/building-your-persons-care-team, Markdown: https://parkinsonspathways.com/caregivers/building-your-persons-care-team.md
- Talking to Kids About a Parent's or Grandparent's Parkinson's, HTML: https://parkinsonspathways.com/caregivers/talking-to-kids-about-a-parents-parkinsons, Markdown: https://parkinsonspathways.com/caregivers/talking-to-kids-about-a-parents-parkinsons.md
- Anticipatory Grief: Mourning Someone Who Is Still Here, HTML: https://parkinsonspathways.com/caregivers/anticipatory-grief-parkinsons-caregiver, Markdown: https://parkinsonspathways.com/caregivers/anticipatory-grief-parkinsons-caregiver.md
- Managing Medication Schedules When Timing Actually Matters, HTML: https://parkinsonspathways.com/caregivers/managing-medication-schedules-parkinsons, Markdown: https://parkinsonspathways.com/caregivers/managing-medication-schedules-parkinsons.md
- Caregiver Burnout Is Not a Character Flaw, HTML: https://parkinsonspathways.com/caregivers/caregiver-burnout-is-not-a-character-flaw, Markdown: https://parkinsonspathways.com/caregivers/caregiver-burnout-is-not-a-character-flaw.md
- Power of Attorney and Advance Directives: Do It Now, Not Later, HTML: https://parkinsonspathways.com/caregivers/power-of-attorney-and-advance-directives-parkinsons, Markdown: https://parkinsonspathways.com/caregivers/power-of-attorney-and-advance-directives-parkinsons.md
- When Your Person Can't Consent: Legal and Ethical Considerations for Trial Enrollment, HTML: https://parkinsonspathways.com/caregivers/when-your-person-cant-consent-clinical-trial-enrollment, Markdown: https://parkinsonspathways.com/caregivers/when-your-person-cant-consent-clinical-trial-enrollment.md
- Your Role During a Clinical Trial: What to Expect as the Care Partner, HTML: https://parkinsonspathways.com/caregivers/your-role-during-a-clinical-trial-care-partner, Markdown: https://parkinsonspathways.com/caregivers/your-role-during-a-clinical-trial-care-partner.md

## PD Curated: Trial Pages (Markdown twins)

Every recruiting Parkinson's trial has a Markdown twin at `/trial/{nctId}.md` containing the AI summary, five-word goal, plain-language eligibility, geocoded sites, contact info, and recent site changes (last 30 days). Append `.md` to any `/trial/{nctId}` URL in the sitemap to reach its twin; below are the 50 most recently updated for quick discovery.

- Improve speech cough and breathing (NCT07674264), HTML: https://parkinsonspathways.com/trial/NCT07674264, Markdown: https://parkinsonspathways.com/trial/NCT07674264.md
- Hands on treatment improves sleep (NCT06671600), HTML: https://parkinsonspathways.com/trial/NCT06671600, Markdown: https://parkinsonspathways.com/trial/NCT06671600.md
- Retrain driving skills using simulator (NCT03969927), HTML: https://parkinsonspathways.com/trial/NCT03969927, Markdown: https://parkinsonspathways.com/trial/NCT03969927.md
- Monitor gait and tremor remotely (NCT06573762), HTML: https://parkinsonspathways.com/trial/NCT06573762, Markdown: https://parkinsonspathways.com/trial/NCT06573762.md
- Brain stimulation improves sleep quality (NCT07636720), HTML: https://parkinsonspathways.com/trial/NCT07636720, Markdown: https://parkinsonspathways.com/trial/NCT07636720.md
- Blood test detects early Parkinson (NCT05385315), HTML: https://parkinsonspathways.com/trial/NCT05385315, Markdown: https://parkinsonspathways.com/trial/NCT05385315.md
- Reduce nighttime awakenings with stimulation (NCT05070013), HTML: https://parkinsonspathways.com/trial/NCT05070013, Markdown: https://parkinsonspathways.com/trial/NCT05070013.md
- Map brain signals causing tremor (NCT06692920), HTML: https://parkinsonspathways.com/trial/NCT06692920, Markdown: https://parkinsonspathways.com/trial/NCT06692920.md
- Detect early Parkinson brain changes (NCT06449404), HTML: https://parkinsonspathways.com/trial/NCT06449404, Markdown: https://parkinsonspathways.com/trial/NCT06449404.md
- Correlate synaptic loss with cognition (NCT06875765), HTML: https://parkinsonspathways.com/trial/NCT06875765, Markdown: https://parkinsonspathways.com/trial/NCT06875765.md
- Increase cough strength with app (NCT06481540), HTML: https://parkinsonspathways.com/trial/NCT06481540, Markdown: https://parkinsonspathways.com/trial/NCT06481540.md
- Assess safety of Parkinson medication (NCT06809400), HTML: https://parkinsonspathways.com/trial/NCT06809400, Markdown: https://parkinsonspathways.com/trial/NCT06809400.md
- Improve cognitive function with training (NCT06323278), HTML: https://parkinsonspathways.com/trial/NCT06323278, Markdown: https://parkinsonspathways.com/trial/NCT06323278.md
- Improve constipation with fecal transplant (NCT06388863), HTML: https://parkinsonspathways.com/trial/NCT06388863, Markdown: https://parkinsonspathways.com/trial/NCT06388863.md
- Distinguish reflexive tightness from stiffness (NCT06596187), HTML: https://parkinsonspathways.com/trial/NCT06596187, Markdown: https://parkinsonspathways.com/trial/NCT06596187.md
- Image brain cyclooxygenase related inflammation (NCT04396873), HTML: https://parkinsonspathways.com/trial/NCT04396873, Markdown: https://parkinsonspathways.com/trial/NCT04396873.md
- Speech tracks movement mood thinking (NCT05765110), HTML: https://parkinsonspathways.com/trial/NCT05765110, Markdown: https://parkinsonspathways.com/trial/NCT05765110.md
- Reduce tremor and movement stiffness (NCT07572903), HTML: https://parkinsonspathways.com/trial/NCT07572903, Markdown: https://parkinsonspathways.com/trial/NCT07572903.md
- Identify brain changes before symptoms (NCT07265596), HTML: https://parkinsonspathways.com/trial/NCT07265596, Markdown: https://parkinsonspathways.com/trial/NCT07265596.md
- Decision aid improves informed choices (NCT06446505), HTML: https://parkinsonspathways.com/trial/NCT06446505, Markdown: https://parkinsonspathways.com/trial/NCT06446505.md
- Improve sleep with brain stimulation (NCT06914466), HTML: https://parkinsonspathways.com/trial/NCT06914466, Markdown: https://parkinsonspathways.com/trial/NCT06914466.md
- Reduce anxiety symptoms with mirtazapine (NCT06530290), HTML: https://parkinsonspathways.com/trial/NCT06530290, Markdown: https://parkinsonspathways.com/trial/NCT06530290.md
- Increase walking speed and endurance (NCT06707402), HTML: https://parkinsonspathways.com/trial/NCT06707402, Markdown: https://parkinsonspathways.com/trial/NCT06707402.md
- Numbing surgical area speeds recovery (NCT07176494), HTML: https://parkinsonspathways.com/trial/NCT07176494, Markdown: https://parkinsonspathways.com/trial/NCT07176494.md
- Reduce movement slowness and fatigue (NCT06883266), HTML: https://parkinsonspathways.com/trial/NCT06883266, Markdown: https://parkinsonspathways.com/trial/NCT06883266.md
- Discover who may develop Parkinson (NCT04724941), HTML: https://parkinsonspathways.com/trial/NCT04724941, Markdown: https://parkinsonspathways.com/trial/NCT04724941.md
- Improve inspiratory strength and fitness (NCT07010783), HTML: https://parkinsonspathways.com/trial/NCT07010783, Markdown: https://parkinsonspathways.com/trial/NCT07010783.md
- Reduce forward and sideways leaning (NCT07010328), HTML: https://parkinsonspathways.com/trial/NCT07010328, Markdown: https://parkinsonspathways.com/trial/NCT07010328.md
- Gene therapy reduces movement fluctuations (NCT06285643), HTML: https://parkinsonspathways.com/trial/NCT06285643, Markdown: https://parkinsonspathways.com/trial/NCT06285643.md
- Link gut microbiome to tremor (NCT06848192), HTML: https://parkinsonspathways.com/trial/NCT06848192, Markdown: https://parkinsonspathways.com/trial/NCT06848192.md
- Reduce hallucinations delusions and illusions (NCT05824728), HTML: https://parkinsonspathways.com/trial/NCT05824728, Markdown: https://parkinsonspathways.com/trial/NCT05824728.md
- Improve mood through caudate stimulation (NCT07409207), HTML: https://parkinsonspathways.com/trial/NCT07409207, Markdown: https://parkinsonspathways.com/trial/NCT07409207.md
- Improve thinking with scalp stimulation (NCT05808504), HTML: https://parkinsonspathways.com/trial/NCT05808504, Markdown: https://parkinsonspathways.com/trial/NCT05808504.md
- Improve movement by filtering sensations (NCT05482126), HTML: https://parkinsonspathways.com/trial/NCT05482126, Markdown: https://parkinsonspathways.com/trial/NCT05482126.md
- Identify serotonin abnormalities causing pain (NCT06008704), HTML: https://parkinsonspathways.com/trial/NCT06008704, Markdown: https://parkinsonspathways.com/trial/NCT06008704.md
- Detect serotonin loss in Parkinson (NCT05516732), HTML: https://parkinsonspathways.com/trial/NCT05516732, Markdown: https://parkinsonspathways.com/trial/NCT05516732.md
- Improve orthostatic blood pressure stability (NCT06920134), HTML: https://parkinsonspathways.com/trial/NCT06920134, Markdown: https://parkinsonspathways.com/trial/NCT06920134.md
- Reduce freezing episodes during walking (NCT06602544), HTML: https://parkinsonspathways.com/trial/NCT06602544, Markdown: https://parkinsonspathways.com/trial/NCT06602544.md
- New drug to slow Parkinson (NCT04691661), HTML: https://parkinsonspathways.com/trial/NCT04691661, Markdown: https://parkinsonspathways.com/trial/NCT04691661.md
- Improve sleep with brain stimulation (NCT05962489), HTML: https://parkinsonspathways.com/trial/NCT05962489, Markdown: https://parkinsonspathways.com/trial/NCT05962489.md
- Improve balance using wearable technology (NCT05680597), HTML: https://parkinsonspathways.com/trial/NCT05680597, Markdown: https://parkinsonspathways.com/trial/NCT05680597.md
- Reduce falls with treadmill training (NCT07058285), HTML: https://parkinsonspathways.com/trial/NCT07058285, Markdown: https://parkinsonspathways.com/trial/NCT07058285.md
- Reduce wearing off between doses (NCT07432958), HTML: https://parkinsonspathways.com/trial/NCT07432958, Markdown: https://parkinsonspathways.com/trial/NCT07432958.md
- Cell transplant improves movement symptoms (NCT07572071), HTML: https://parkinsonspathways.com/trial/NCT07572071, Markdown: https://parkinsonspathways.com/trial/NCT07572071.md
- Improve thinking with brain stimulation (NCT05968703), HTML: https://parkinsonspathways.com/trial/NCT05968703, Markdown: https://parkinsonspathways.com/trial/NCT05968703.md
- Improve cognition through aerobic exercise (NCT07299279), HTML: https://parkinsonspathways.com/trial/NCT07299279, Markdown: https://parkinsonspathways.com/trial/NCT07299279.md
- Identify immune triggers of Parkinson (NCT04239079), HTML: https://parkinsonspathways.com/trial/NCT04239079, Markdown: https://parkinsonspathways.com/trial/NCT04239079.md
- Improve speech clarity through listening (NCT07403539), HTML: https://parkinsonspathways.com/trial/NCT07403539, Markdown: https://parkinsonspathways.com/trial/NCT07403539.md
- Reduce freezing and improve walking (NCT06791902), HTML: https://parkinsonspathways.com/trial/NCT06791902, Markdown: https://parkinsonspathways.com/trial/NCT06791902.md
- Brain controlled training improves walking (NCT06690931), HTML: https://parkinsonspathways.com/trial/NCT06690931, Markdown: https://parkinsonspathways.com/trial/NCT06690931.md

## Universal Raw Mirror (any condition)

A separate, condition-agnostic mirror of ClinicalTrials.gov. **Raw data only, no AI summaries, no PD-specific filtering, no editorial enrichment.** Use this when you want source-of-truth data with field-level change tracking.

- URL pattern: https://parkinsonspathways.com/agent/trials/{nctId}.md
- Authoritative source: https://clinicaltrials.gov/study/{nctId}

## Agent API

A programmatic API namespace for agents and downstream services is in the works. Entry point will live at `https://parkinsonspathways.com/api/agent/` and will expose change feeds, matching, and replay endpoints. Until that ships, retrieve content via the Markdown URLs above.

## Machine-Readable Resources

- [Sitemap](https://parkinsonspathways.com/sitemap.xml), clean HTML URLs for every public page (only `/trial/{nctId}`, `/learn/{slug}`, `/trials-near-me`, `/trials-near-me/{city}`, `/trials/{type}/{slug}` entries support a `.md` twin)
- [Sitemap Index](https://parkinsonspathways.com/sitemap-index.xml), references the main sitemap
- [Full LLM Context](https://parkinsonspathways.com/llms-full.txt)