---
title: Improve targeting for brain stimulation
nct_id: NCT00575081
status: RECRUITING
sponsor: Vanderbilt University Medical Center
study_type: OBSERVATIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT00575081"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT00575081"
last_fetched: "2026-05-10T14:06:56.416Z"
source: "Parkinson's Pathways (curated)"
---
# Improve targeting for brain stimulation

**Goal (in five words):** Improve targeting for brain stimulation

**Official Title:** Physiological Brain Atlas Development

**Trial ID:** [NCT00575081](https://clinicaltrials.gov/study/NCT00575081)

## Key Facts

- **Status:** RECRUITING
- **Study Type:** OBSERVATIONAL
- **Sponsor:** Vanderbilt University Medical Center
- **Target Enrollment:** 5000 participants
- **Start Date:** 2006-08
- **Completion Date:** 2026-08
- **Conditions:** Parkinson's Disease, Obsessive Compulsive Disorder, Dystonia, Essential Tremor, Epilepsy
- **Interventions:** Stereotactic brain procedures
- **Intervention Types:** DEVICE

## Summary For Families

The goal is to build a detailed physiological atlas of brain signals to help surgeons find the exact spots for stereotactic procedures like deep brain stimulation, lesioning, or electrode placement in Parkinson's and related movement and seizure disorders. During the stereotactic procedures the team records electrical and other physiological signals from targeted brain areas, mapping those signals to anatomy so future treatments can be targeted more precisely; no new drug or experimental treatment is given, the study collects data during procedures you would already be having. The study is open to people aged 6 to 90 who have been recommended for and consent to a stereotactic brain procedure, and it excludes anyone not recommended or not able to give informed consent.

## Eligibility

- **Minimum age:** 6 Years
- **Maximum age:** 90 Years
- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

* All patients who are recommended for Stereotactic Brain procedures
* Any patient who has agreed to undergo a Stereotactic Brain procedure
* Patients age under 6 -90 years old

Exclusion Criteria:

* Patients who fail recommendation for Stereotactic Brain procedures
* Patients not consented for Stereotactic Brain procedures
* Patients outside the age range of 6 -90 years old
* Patients or legal guardians not able to provide informed consent
```

## Locations (1)

- Vanderbilt Univeristy, Nashville, Tennessee, United States _(36.1659, -86.7844)_
  - Dario J Englot, MD, Ph.D. — (CONTACT) — 615-322-7417 — dario.englot@vumc.org
  - Wuraola T Adesinasi@vumc.org — (CONTACT) — wuraola.a.adesinasi@vumc.org
  - Benoit Dawant, Ph.D. — (SUB_INVESTIGATOR)
  - Hong Yu, MD — (SUB_INVESTIGATOR)
  - Changqing Kao, MD, Ph.D. — (SUB_INVESTIGATOR)
  - Dario Englot, MD, PhD — (SUB_INVESTIGATOR)

## Central Contacts

- Dario J Englot, MD, Ph.D. — (CONTACT) — 615-322-7417 — dario.englot@vumc.org
- Wuraola a Adesinasi — (CONTACT) — wuraola.a.adesinasi@vumc.org

---

*Canonical: https://parkinsonspathways.com/trial/NCT00575081*  
*HTML version: https://parkinsonspathways.com/trial/NCT00575081*  
*Source data: https://clinicaltrials.gov/study/NCT00575081*