--- title: Reduce tremor stiffness and slowness nct_id: NCT02071134 status: RECRUITING sponsor: Boston Scientific Corporation study_type: OBSERVATIONAL canonical_url: "https://parkinsonspathways.com/trial/NCT02071134" clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT02071134" last_fetched: "2026-05-10T14:08:25.916Z" source: "Parkinson's Pathways (curated)" --- # Reduce tremor stiffness and slowness **Goal (in five words):** Reduce tremor stiffness and slowness **Official Title:** Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry **Trial ID:** [NCT02071134](https://clinicaltrials.gov/study/NCT02071134) ## Key Facts - **Status:** RECRUITING - **Study Type:** OBSERVATIONAL - **Sponsor:** Boston Scientific Corporation - **Target Enrollment:** 1500 participants - **Start Date:** 2014-03-04 - **Completion Date:** 2038-12 - **Conditions:** Parkinson's Disease - **Interventions:** Deep Brain Stimulation (DBS) - **Intervention Types:** DEVICE ## Summary For Families The goal is to gather real-world safety and outcome data on the Vercise deep brain stimulation system in people with Parkinson's, so doctors and patients can see how well the device works and how it performs over time. The Vercise system uses implanted leads to send focused electrical pulses to movement-related brain regions, such as the subthalamic nucleus or globus pallidus, to reduce tremor, stiffness, and slowness, and its directional/current-controlled stimulation aims to maximize benefit while limiting side effects, which can allow some people to reduce levodopa doses. As an observational registry, clinicians simply follow and record outcomes for people who receive the device in routine care rather than assigning treatments. Adults 18 and older who meet the local Vercise device guidelines and have no device contraindications can be enrolled; significant cognitive or psychiatric impairment may exclude someone. ## Eligibility - **Minimum age:** 18 Years - **Sex:** ALL ### Full Criteria ``` Key Inclusion Criteria: * Meets criteria established in locally applicable Vercise System Direction for Use * At least 18 years old Key Exclusion Criteria: * Meets any contraindication in the Vercise System locally applicable Directions for Use Subjects with significant cognitive or psychiatric impairment may be excluded in the evaluation of GXT. ``` ## Locations (84) - Neurology and Pain Specialty, Aliso Viejo, California, United States _(33.5650, -117.7271)_ - Cedars Sinai Medical Center, Los Angeles, California, United States _(34.0522, -118.2437)_ - Boston Scientific Clinical Research — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - University of Colorado, Aurora, Colorado, United States _(39.7294, -104.8319)_ - Boston Scientific Clinical Research — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - St. Mary's Hospital and Medical Center, Grand Junction, Colorado, United States _(39.0639, -108.5507)_ - Boston Scientific Clinical Research — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - University of Florida Shands Hospital, Gainesville, Florida, United States _(29.6516, -82.3248)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Mayo Clinic, Jacksonville, Jacksonville, Florida, United States _(30.3322, -81.6556)_ - University of Miami Hospital, Miami, Florida, United States _(25.7743, -80.1937)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Tallahassee Neurological Clinic, PA, Tallahassee, Florida, United States _(30.4383, -84.2807)_ - University of South Florida, Tampa, Florida, United States _(27.9475, -82.4584)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - St. Luke Regional Medical Center, Boise, Idaho, United States _(43.6135, -116.2035)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Rush University Medical Center, Chicago, Illinois, United States _(41.8500, -87.6500)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Methodist Hospital of Indianapolis, Indianapolis, Indiana, United States _(39.7684, -86.1580)_ - Massachusetts General Hospital, Boston, Massachusetts, United States _(42.3584, -71.0598)_ - St. Louis University Hospital, St Louis, Missouri, United States _(38.6273, -90.1979)_ - Albany Medical College, Albany, New York, United States _(42.6526, -73.7562)_ - Northwell Health Neuroscience Institute, Great Neck, New York, United States _(40.8007, -73.7285)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - University at Buffalo, Williamsville, New York, United States _(42.9639, -78.7378)_ - Boston Scientific Clinical Research — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States _(36.0999, -80.2442)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Cleveland Clinic Foundation, Cleveland, Ohio, United States _(41.4995, -81.6954)_ - Ohio State University, Columbus, Ohio, United States _(39.9612, -82.9988)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Vanderbilt University, Nashville, Tennessee, United States _(36.1659, -86.7844)_ - Houston Methodist Research Institute, Houston, Texas, United States _(29.7633, -95.3633)_ - Boston Scientific Clinical Research — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - University of Texas Health Medical Arts and Research Center, San Antonio, Texas, United States _(29.4241, -98.4936)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Texas Institute for Neurological Disorders, Sherman, Texas, United States _(33.6357, -96.6089)_ - Boston Scientific Clinical Research — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - University of Virginia Medical Center, Charlottesville, Virginia, United States _(38.0293, -78.4767)_ - Evergreen Health, Kirkland, Washington, United States _(47.6815, -122.2087)_ - Boston Scientific Clinical Research — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - University of Washington Medical Center, Seattle, Washington, United States _(47.6062, -122.3321)_ - Boston Scientific Clinical Research — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Inland Northwest Research, Spokane, Washington, United States _(47.6597, -117.4291)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Fundacion Ineco-Research Facility, Buenos Aires, Argentina _(-34.6131, -58.3772)_ - A.o. LKH Univ.-Kliniken Innsbruck, Innsbruck, Austria _(47.2627, 11.3945)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - AZ Sint-Lucas, Ghent, Belgium _(51.0500, 3.7167)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - UZ Gasthuisberg, Leuven, Belgium _(50.8796, 4.7009)_ - Boston Scientific Clinical Research — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - AZ Delta, Roeselare, Belgium _(50.9465, 3.1227)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Queen Elizabeth II Health Sciences Center, Halifax, Canada _(44.6427, -63.5769)_ - Hopital de Enfant-Jesus, Québec, Canada _(46.8123, -71.2145)_ - CHU Henri Mondor, Créteil, France _(48.7927, 2.4657)_ - Hopital Neurologique Pierre Wertheimer, Lyon, France _(45.7491, 4.8479)_ - CHU La Timone Hospital, Marseille, France _(43.2970, 5.3811)_ - Boston Scientific Clinical Research — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Fondation Ophtalmologique Adolphe de Rothschild, Paris, France _(48.8534, 2.3488)_ - CHRU Hopital Pontchaillou, Rennes, France _(48.1111, -1.6743)_ - University Berlin, Charite Virchow Standort, Wedding, Berlin, Germany _(52.5244, 13.4105)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Uniklinik Köln, Cologne, Germany _(50.9333, 6.9500)_ - Universitätsklinikum Düsseldorf, Düsseldorf, Germany _(51.2232, 6.7793)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Universitätsklinikum Freiburg, Freiburg im Breisgau, Germany _(47.9959, 7.8522)_ - Universitätsklinik Eppendorf, Hamburg, Germany _(53.5507, 9.9930)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - St. Barbara-Klinik Hamm-Heessen, Hamm, Germany _(51.6803, 7.8209)_ - Universitätsklinikum Campus Kiel, Kiel, Germany _(54.3213, 10.1349)_ - Johannes Gutenberg Universitaet Mainz, Mainz, Germany _(49.9819, 8.2801)_ - Universitaetsklinikum Giessen und Marburg GmbH, Marburg, Germany _(50.8090, 8.7707)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Evangelisches Krankenhaus Oldenburg, Oldenburg, Germany _(53.1404, 8.2148)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Universitätsklinikum Würzburg, Würzburg, Germany _(49.7939, 9.9512)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Medical School of University PECS, Pécs, Hungary _(46.0762, 18.2281)_ - Hadassah Hebrew University Medical Center, Jerusalem, Israel _(31.7690, 35.2163)_ - Tel Aviv Sourasky Medical Center, Tel Aviv, Israel _(32.0809, 34.7806)_ - Sheba Medical Center, Tel Litwinsky, Israel _(32.0510, 34.8459)_ - Villa Margherita, Arcugnano, Italy _(45.4958, 11.5477)_ - Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy _(44.8380, 11.6206)_ - Ospedale Dell Angelo, Mestre, Italy _(45.4917, 12.2454)_ - IRCCS Istituto Ortopedico Galeazzi, Milan, Italy _(45.4643, 9.1895)_ - Fondazione Istituto Neurologico Casimiro Mondino, Pavia, Italy _(45.1921, 9.1592)_ - Policlinico Universitario Agostino Gemelli, Rome, Italy _(41.8919, 12.5113)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Osp. S. Maria Della Misericordia, Udine, Italy _(46.0693, 13.2371)_ - 10 Military Clinical Hospital Bydgoszcz, Bydgoszcz, Poland _(53.1235, 18.0076)_ - Podmiot Leczniczy Copernicus Sp. z o.o., Gdansk, Poland _(54.3523, 18.6491)_ - Centrum Onkologii - Instytut im. Marii Sklodowskiej-Curie, Warsaw, Poland _(52.2298, 21.0118)_ - Samsung Medical Center, Seoul, South Korea _(37.5660, 126.9784)_ - Boston Scientific Clinical Research Manager — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Seoul ASAN Medical Center, Seoul, South Korea _(37.5660, 126.9784)_ - Yonsei University Severance Hospital, Seoul, South Korea _(37.5660, 126.9784)_ - Hospital Clinic de Barcelona, Barcelona, Spain _(41.3888, 2.1590)_ - Hospital De Bellvitge, Barcelona, Spain _(41.3888, 2.1590)_ - Centro Especial Ramon y Cajal, Madrid, Spain _(40.4165, -3.7026)_ - Hospital Clinico San Carlos, Madrid, Spain _(40.4165, -3.7026)_ - University Hospital Virgen Arrixaca, Murcia, Spain _(37.9870, -1.1300)_ - Hospital General De Asturias, Oviedo, Spain _(43.3603, -5.8448)_ - Bahcesehir University Hospital Medical Park Goztepe, Istanbul, Turkey (Türkiye) _(41.0138, 28.9497)_ - Boston Scientific Clinical Research — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Koc University Hospital, Istanbul, Turkey (Türkiye) _(41.0138, 28.9497)_ - Boston Scientific Clinical Research — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Southmead Hospital Bristol, Bristol, United Kingdom _(51.4552, -2.5966)_ - Queen Elizabeth University Hospital, Glasgow, United Kingdom _(55.8651, -4.2576)_ - The Walton Centre, Liverpool, United Kingdom _(53.4106, -2.9779)_ - Charing Cross Hospital, London, United Kingdom _(51.5085, -0.1257)_ - King's College Hospital London, London, United Kingdom _(51.5085, -0.1257)_ - St. Georges Hospital, London, United Kingdom _(51.5085, -0.1257)_ - Royal Victoria Infirmary, Newcastle, United Kingdom _(54.2180, -5.8898)_ - John Radcliffe Hospital, Oxford, United Kingdom _(51.7522, -1.2560)_ ## Central Contacts - Heleen Scholtes — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com - Alison Lewis — (CONTACT) — 855-213-9890 — BSNClinicalTrials@bsci.com --- *Canonical: https://parkinsonspathways.com/trial/NCT02071134* *HTML version: https://parkinsonspathways.com/trial/NCT02071134* *Source data: https://clinicaltrials.gov/study/NCT02071134*