---
title: Predict symptoms and personalize care
nct_id: NCT03523065
status: RECRUITING
sponsor: Xiangya Hospital of Central South University
study_type: OBSERVATIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT03523065"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT03523065"
last_fetched: "2026-05-10T14:07:59.016Z"
source: "Parkinson's Pathways (curated)"
---
# Predict symptoms and personalize care

**Goal (in five words):** Predict symptoms and personalize care

**Official Title:** The Chinese Parkinson's Disease With GBA Variants Registry

**Trial ID:** [NCT03523065](https://clinicaltrials.gov/study/NCT03523065)

## Key Facts

- **Status:** RECRUITING
- **Study Type:** OBSERVATIONAL
- **Sponsor:** Xiangya Hospital of Central South University
- **Target Enrollment:** 500 participants
- **Start Date:** 2017-02-01
- **Completion Date:** 2027-02-01
- **Conditions:** Parkinson Disease

## Summary For Families

The goal is to learn how variants in the GBA gene affect Parkinson's symptoms, progression, and treatment responses so clinicians can better predict outcomes and personalize care. Instead of testing a drug, researchers are creating a registry that gathers genetic and clinical data and follows about 500 people over time, tracking things like symptom patterns and how patients respond to treatments such as levodopa. Enrollment is for people diagnosed with Parkinson's by standard criteria who have a confirmed GBA variant, the trial lists no age limits and accepts all sexes.

## Eligibility

- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

* Patients diagnosed with PD by the United Kingdom Parkinson's Disease Society Brain Bank clinical diagnostic criteria or other standard criteria; PD patients detected with GBA gene variants.

Exclusion Criteria:

\-
```

## Locations (1)

- Xiangya Hospital of Central South University, Changsha, Hunan, China _(28.1987, 112.9709)_
  - Jifeng Guo, Ph.D. — (CONTACT) — +8613974936815 — guojifeng2003@163.com
  - Qiying Sun, Ph.D. — (CONTACT) — +8615874907260 — sunqiying2015@163.com

## Central Contacts

- Jifeng Guo, Ph.D. — (CONTACT) — +8613974936815 — guojifeng2003@163.com
- Beisha Tang, Ph.D. — (CONTACT) — +8613974856709 — bstang7398@163.com

---

*Canonical: https://parkinsonspathways.com/trial/NCT03523065*  
*HTML version: https://parkinsonspathways.com/trial/NCT03523065*  
*Source data: https://clinicaltrials.gov/study/NCT03523065*