---
title: Map Parkinson progression in carriers
nct_id: NCT03523104
status: RECRUITING
sponsor: Xiangya Hospital of Central South University
study_type: OBSERVATIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT03523104"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT03523104"
last_fetched: "2026-05-10T14:05:10.716Z"
source: "Parkinson's Pathways (curated)"
---
# Map Parkinson progression in carriers

**Goal (in five words):** Map Parkinson progression in carriers

**Official Title:** The Chinese Parkinson's Disease With LRRK2 Variants Registry

**Trial ID:** [NCT03523104](https://clinicaltrials.gov/study/NCT03523104)

## Key Facts

- **Status:** RECRUITING
- **Study Type:** OBSERVATIONAL
- **Sponsor:** Xiangya Hospital of Central South University
- **Target Enrollment:** 1000 participants
- **Start Date:** 2017-02-01
- **Completion Date:** 2027-02-01
- **Conditions:** Parkinson Disease

## Summary For Families

The goal is to map how Parkinson's linked to changes in the LRRK2 gene presents and progresses, so researchers can better understand symptoms, progression, and treatment responses in this genetic subgroup. The project is an observational registry that collects medical history, genetic test results, and follow-up clinical data rather than testing a treatment, building a large dataset to study genotype-phenotype links and the natural history of LRRK2-associated PD. Enrollment is open in China to people diagnosed with Parkinson's who have a confirmed LRRK2 variant, the registry plans about 1,000 participants, and no age or sex limits are listed.

## Eligibility

- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

* Patients diagnosed with PD by the United Kingdom Parkinson's Disease Society Brain Bank clinical diagnostic criteria or other standard criteria; PD patients detected with positive LRRK2 variants

Exclusion Criteria:

\-
```

## Locations (1)

- Xiangya Hospital of Central South University, Changsha, Hunan, China _(28.1987, 112.9709)_
  - Jifeng Guo, Ph.D. — (CONTACT) — +8613974936815 — guojifeng2003@163.com
  - Qiying Sun, Ph.D. — (CONTACT) — +8615874907260 — sunqiying2015@163.com

## Central Contacts

- Jifeng Guo, Ph.D. — (CONTACT) — +8613974936815 — guojifeng2003@163.com
- Beisha Tang, Ph.D. — (CONTACT) — +8613974856709 — bstang7398@163.com

---

*Canonical: https://parkinsonspathways.com/trial/NCT03523104*  
*HTML version: https://parkinsonspathways.com/trial/NCT03523104*  
*Source data: https://clinicaltrials.gov/study/NCT03523104*