---
title: Improve gait and balance remotely
nct_id: NCT04720365
phase: NA
status: RECRUITING
sponsor: University Hospital, Rouen
study_type: INTERVENTIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT04720365"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT04720365"
last_fetched: "2026-05-10T14:07:17.316Z"
source: "Parkinson's Pathways (curated)"
---
# Improve gait and balance remotely

**Goal (in five words):** Improve gait and balance remotely

**Official Title:** Medico-economic Evaluation Rehabilitation by Serious Games at Home for the Management of Patients With Parkinson's Disease Suffering From Gait and Balance Disorders

**Trial ID:** [NCT04720365](https://clinicaltrials.gov/study/NCT04720365)

## Key Facts

- **Phase:** NA
- **Status:** RECRUITING
- **Study Type:** INTERVENTIONAL
- **Sponsor:** University Hospital, Rouen
- **Target Enrollment:** 80 participants
- **Start Date:** 2023-02-15
- **Completion Date:** 2029-02-01
- **Conditions:** Patients With Parkinson's Disease
- **Interventions:** play-based rehabilitaion
- **Intervention Types:** DEVICE

## Summary For Families

The goal is to reduce falls and improve walking and balance in people with Parkinson's whose gait and balance problems do not get better with levodopa. At home, participants use interactive serious games that guide repetitive balance and walking exercises, give real-time feedback and motivation, and aim to retrain posture and stepping patterns; this is a non-drug add-on and medications like levodopa are kept unchanged. Eligible people are adults 18 and older with idiopathic Parkinson's who still have gait or freezing despite levodopa, have had at least two falls in the past year, have stable Parkinson medications and an internet connection at home, while those with severe immobility, moderate to severe dementia, no internet, or other major exclusions are not eligible.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

1. Diagnosis of idiopathic Parkinson's disease (according to United Kingdom Parkinson's Disease Society Brain Bank \[UKPDD\] criteria) ;
2. Age ≥ 18 years ;
3. Patient with gait and/or balance disorders not improved by levodopa treatment with item 12 "walking and balance" ≥ 1 of the MDS-UPDRS (Movement-Disorders Society-Unified Parkinson's disease rating scale) part II, ON levodopa and/or item 13 of "gait freezing" ≥ 1 (Goetz, Tilley et al. 2008);
4. Number of falls ≥ 2 in the previous year;
5. Stable antiparkinsonian treatments for at least 1 month prior to inclusion in the study ;
6. Patient with social health insurance ;
7. Person who voluntarily and informedly agreed to participate in the study (signed written consent) ;
8. Other medical problems that are stable or do not interfere with the proposed protocol;

Exclusion Criteria:

1. Parkinson's disease with Hoehn\&Yahr stage 5 corresponding to an inability of the subject to stand or walk alone ;
2. Dementia (MMS \< 24 and/or MoCA \< 18) ;
3. Presence of an impulse control disorder defined by item 6 of the MDS-UPDRS part I \> 2 ;
4. Absence of internet connection at home ;
5. Serious pathology interfering with the test ;
6. Estimated life expectancy of less than 2 years ;
7. Subject in a period of exclusion from further research ;
8. Persons under guardianship, curatorship or any other administrative or judicial measure of deprivation of rights and liberty ;
9. Pregnant woman or woman of childbearing age without contraceptive methods;
```

## Locations (4)

- Chu Bordeaux, Bordeaux, France _(44.8412, -0.5805)_
  - Dominique Guehl, Pr — (CONTACT) — 05 57 57 15 51 — dominique.guehl@ubordeaux2.fr
  - Dominique Guehl, Pr — (SUB_INVESTIGATOR)
- Chu Lille, Lille, France _(50.6339, 3.0551)_
  - Caroline Moreau, Pr — (CONTACT) — 03 20 44 59 62 — caroline.moreau@chru-lille.fr
  - Caroline Moreau, Pr — (SUB_INVESTIGATOR)
- Gh Pitie Salpetriere, Paris, France _(48.8534, 2.3488)_
  - Louise Laure Mariani, Dr — (CONTACT) — 01 42 17 62 05 — louiselaure.mariani@aphp.fr
  - Louise Laure Mariani, Dr — (SUB_INVESTIGATOR)
- Rouen University Hospital, Rouen, France _(49.4431, 1.0993)_
  - Marie-Laure WELTER, Professor — (CONTACT) — 02 32 88 80 37 — Marie-Laure.Welter@chu-rouen.fr
  - Marie-Laure Welter, Pr — (PRINCIPAL_INVESTIGATOR)

## Central Contacts

- Nell Marty — (CONTACT) — (33) 02 32 88 82 65 — Nell.Marty@chu-rouen.fr

---

*Canonical: https://parkinsonspathways.com/trial/NCT04720365*  
*HTML version: https://parkinsonspathways.com/trial/NCT04720365*  
*Source data: https://clinicaltrials.gov/study/NCT04720365*