Identify brain activity underlying impulsivity
- Trial ID
- NCT05353855
- Official Title
- Neural Correlates of Impulsivity in Idiopathic REM Sleep Behavior Disorder: a Functional Magnetic Resonance Imaging Case-control Study
- Goal
- Identify brain activity underlying impulsivity
- Status
- RECRUITING
- Sponsor
- Chinese University of Hong Kong
- Study Type
- OBSERVATIONAL
- Enrollment
- 96 participants
- Conditions
- Parkinson Disease
- Interventions
- No intervention
Plain-Language Summary
The project aims to pinpoint the brain activity patterns that underlie impulsivity in people with idiopathic REM sleep behavior disorder, since iRBD can precede Parkinson's and impulsive behaviors affect safety and daily life. Researchers are using functional MRI to map which brain networks show altered activity during impulsivity-related tasks or at rest, there is no drug or device being tested, and fMRI works by detecting blood flow changes that reflect neural activity. They are enrolling age- and sex-matched adults 50 and older; for the non-RBD/control arm participants must have no personal or family history of PD or RBD, no dream-enactment or REM sleep without atonia on sleep study, no dementia, mood disorder, narcolepsy, or prior impulse control disorder, no MRI contraindications, and not be taking medications that can induce impulsivity.
Locations
- The Chinese University of Hong Kong, Hong Kong, Hong Kong
Frequently Asked Questions
- What is this trial testing?
- This trial is studying No intervention. The project aims to pinpoint the brain activity patterns that underlie impulsivity in people with idiopathic REM sleep behavior disorder, since iRBD can precede Parkinson's and impulsive behaviors affect safety and daily life. Researchers are using functional MRI to map which brain networks show altered activity during impulsivity-related tasks or at rest, there is no drug or device being tested, and fMRI works by detecting blood flow changes that reflect neural activity. They are enrolling age- and sex-matched adults 50 and older; for the non-RBD/control arm participants must have no personal or family history of PD or RBD, no dream-enactment or REM sleep without atonia on sleep study, no dementia, mood disorder, narcolepsy, or prior impulse control disorder, no MRI contraindications, and not be taking medications that can induce impulsivity.
- Who can participate?
- Participants must be at least 50 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 2 years and 11 months.