Predict Parkinson progression from microbiota
- Trial ID
- NCT05353868
- Official Title
- Gut Microbiota in the Progression of Alpha-synucleinopathies: a Prospective Follow-up Study
- Goal
- Predict Parkinson progression from microbiota
- Status
- RECRUITING
- Sponsor
- Chinese University of Hong Kong
- Study Type
- OBSERVATIONAL
- Enrollment
- 490 participants
- Conditions
- REM Sleep Behavior Disorder
- Interventions
- No intervention
Plain-Language Summary
The goal is to see whether patterns in gut bacteria predict which people with REM sleep behavior disorder later develop Parkinson's or other alpha-synuclein diseases. Researchers are following about 490 people over time, collecting stool samples and clinical data without giving any treatment, and sequencing the microbiota to spot changes linked to disease progression. Participants must have completed the prior baseline study, be able to give informed consent, and must not have used probiotics or antibiotics in the past three months or have pre-existing gastrointestinal diseases like inflammatory bowel disease.
Locations
- The Chinese University of Hong Kong, Hong Kong, Hong Kong
Frequently Asked Questions
- What is this trial testing?
- This trial is studying No intervention. The goal is to see whether patterns in gut bacteria predict which people with REM sleep behavior disorder later develop Parkinson's or other alpha-synuclein diseases. Researchers are following about 490 people over time, collecting stool samples and clinical data without giving any treatment, and sequencing the microbiota to spot changes linked to disease progression. Participants must have completed the prior baseline study, be able to give informed consent, and must not have used probiotics or antibiotics in the past three months or have pre-existing gastrointestinal diseases like inflammatory bowel disease.
- Who can participate?
- Eligibility criteria vary. Check the full listing on ClinicalTrials.gov for detailed inclusion and exclusion criteria.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 2 years and 5 months.