---
title: Detect early Parkinson via blood
nct_id: NCT05385315
status: RECRUITING
sponsor: University Hospital, Grenoble
study_type: OBSERVATIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT05385315"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT05385315"
last_fetched: "2026-05-10T14:04:53.645Z"
source: "Parkinson's Pathways (curated)"
---
# Detect early Parkinson via blood

**Goal (in five words):** Detect early Parkinson via blood

**Official Title:** Evaluation De La Performance Clinique D'un Nouveau Biomarqueur Sanguin Des Phases Précoces De La Maladie De Parkinson

**Trial ID:** [NCT05385315](https://clinicaltrials.gov/study/NCT05385315)

## Key Facts

- **Status:** RECRUITING
- **Study Type:** OBSERVATIONAL
- **Sponsor:** University Hospital, Grenoble
- **Target Enrollment:** 70 participants
- **Start Date:** 2022-10-13
- **Completion Date:** 2025-10-16
- **Conditions:** Parkinson Disease

## Summary For Families

The goal is to test a new blood biomarker that could detect Parkinson's disease early and help distinguish Parkinson's from similar conditions like multiple system atrophy. The approach is observational blood sampling to measure a specific molecular signature or disease‑related proteins in the blood, seeing if that signature reliably marks Parkinson's pathology without changing any treatments. Adults 18 and older are eligible if they are newly diagnosed and not yet on dopaminergic drugs, have advanced Parkinson's treated for more than five years, or have multiple system atrophy, while people with deep brain stimulation or other neurodegenerative diseases are excluded.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

* Patients with de novo Parkinson's disease, without dopaminergic treatment
* Patients with advanced Parkinson's disease (\> 5years) with dopaminergic treatment
* Patients with multiple system atrophy

Exclusion Criteria:

* Patients with deep brain stimulation
* Other neurodegenerative diseases
* patients protected by french law (pregnant or lactating women, prisoners, ...)
```

## Locations (1)

- CHU Grenoble Alpes, Grenoble, France _(45.1787, 5.7148)_
  - Florence FAUVELLE — (CONTACT) — +33 (0)4 56 52 06 00 — florence.fauvelle@univ-grenoble-alpes.fr
  - Andrea KISTNER, PhD — (CONTACT) — +33 (0)4 76765791 — AKistner@chu-grenoble.fr
  - ELENA MORO — (CONTACT)

## Central Contacts

- Florence Fauvelle, PhD — (CONTACT) — (33)456520600 — florence.fauvelle@univ-grenoble-alpes.fr
- Andrea Kistner, PhD — (CONTACT) — Akistner@chu-grenoble.fr

---

*Canonical: https://parkinsonspathways.com/trial/NCT05385315*  
*HTML version: https://parkinsonspathways.com/trial/NCT05385315*  
*Source data: https://clinicaltrials.gov/study/NCT05385315*