Improve cognition through microbiome modulation
- Trial ID
- NCT05419453
- Official Title
- Microbiome Composition and Function Contributes to Cognitive Impairment and Neuroinflammation in Parkinson's Disease
- Goal
- Improve cognition through microbiome modulation
- Status
- RECRUITING
- Sponsor
- California State University, San Bernardino
- Study Type
- OBSERVATIONAL
- Enrollment
- 100 participants
- Conditions
- Parkinson Disease
Plain-Language Summary
The trial is looking at whether the make-up and activity of gut bacteria are linked to thinking problems and brain inflammation in people with Parkinson's. Instead of testing a treatment, researchers will analyze participants' gut microbiome profiles and related biomarkers while doing cognitive assessments to find patterns that might explain or predict cognitive decline. They are enrolling people aged 55 to 85 with Parkinson's, excluding anyone who used antibiotics or immunosuppressants in the past 3 months or who has inflammatory gut disease, major brain injury, stroke, epilepsy, Alzheimer's, or recent psychiatric hospitalizations.
Locations
- California State University San Bernardino, San Bernardino, California, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. The trial is looking at whether the make-up and activity of gut bacteria are linked to thinking problems and brain inflammation in people with Parkinson's. Instead of testing a treatment, researchers will analyze participants' gut microbiome profiles and related biomarkers while doing cognitive assessments to find patterns that might explain or predict cognitive decline. They are enrolling people aged 55 to 85 with Parkinson's, excluding anyone who used antibiotics or immunosuppressants in the past 3 months or who has inflammatory gut disease, major brain injury, stroke, epilepsy, Alzheimer's, or recent psychiatric hospitalizations.
- Who can participate?
- Participants must be between 55 Years and 85 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 4 years and 11 months.