---
title: Use kinematics to diagnose Parkinson
nct_id: NCT06161636
status: RECRUITING
sponsor: "Centre hospitalier de l'Université de Montréal (CHUM)"
study_type: OBSERVATIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT06161636"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06161636"
last_fetched: "2026-05-10T14:04:03.716Z"
source: "Parkinson's Pathways (curated)"
---
# Use kinematics to diagnose Parkinson

**Goal (in five words):** Use kinematics to diagnose Parkinson

**Official Title:** Contribution of the Kinematic Theory in the Early Differential Diagnosis of the Parkinson's Disease

**Trial ID:** [NCT06161636](https://clinicaltrials.gov/study/NCT06161636)

## Key Facts

- **Status:** RECRUITING
- **Study Type:** OBSERVATIONAL
- **Sponsor:** Centre hospitalier de l'Université de Montréal (CHUM)
- **Target Enrollment:** 90 participants
- **Start Date:** 2020-02-19
- **Completion Date:** 2028-12
- **Conditions:** Parkinson Disease, Healthy, Parkinsonian Syndromes

## Summary For Families

The team aims to find out whether detailed movement analysis based on kinematic theory can help tell early Parkinson's disease apart from other parkinsonian syndromes and from normal aging. They use noninvasive recordings of speech and motor movements and apply kinematic modeling to quantify timing and movement trajectories, looking for objective signatures of impaired motor control; some assessments may be done after about 12 hours off antiparkinsonian medication so the results reflect the unmedicated state. The trial is enrolling people aged 50 to 75 with parkinsonism or a related syndrome who have had motor symptoms for six years or less, plus healthy volunteers. People with major cognitive impairment, other neurological diseases, certain prior oromandibular or laryngeal procedures, uncorrected deafness, or any contraindication to pupil dilation are excluded.

## Eligibility

- **Minimum age:** 50 Years
- **Maximum age:** 75 Years
- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

* Being diagnosed with Parkinsonism including idiopathic Parkinson's disease or a related syndrome;
* Have motor symptoms of Parkinsonism for 6 years or less;
* Be a healthy volunteer subject in good general health with no prior neurological history;
* Age between 50-75 years old;
* If applicable, be able to safely leave home in the morning without having taken antiparkinsonian medication for the past 12 hours.

Exclusion Criteria:

* Major neurocognitive disorders;
* History of other neurological conditions, such as ischemic or hemorrhagic stroke, paralysis of a limb, traumatic brain injury, epilepsy, orofacial dystonia, essential tremor;
* History of oromandibular or laryngeal procedures;
* Uncorrected deafness;
* Any contraindication to pupillary dilation.
```

## Locations (1)

- CHUM/Université de Montréal, Montreal, Quebec, Canada _(45.5088, -73.5878)_
  - Pierre Blanchet, MD — (CONTACT) — 514-890-8000 — pierre.j.blanchet@umontreal.ca

## Central Contacts

- Pierre Blanchet, MD — (CONTACT) — 514-890-8123 — pierre.j.blanchet@umontreal.ca

---

*Canonical: https://parkinsonspathways.com/trial/NCT06161636*  
*HTML version: https://parkinsonspathways.com/trial/NCT06161636*  
*Source data: https://clinicaltrials.gov/study/NCT06161636*