---
title: Improve motor function using StimSearch
nct_id: NCT06205043
phase: NA
status: RECRUITING
sponsor: Jaslok Hospital and Research Centre
study_type: INTERVENTIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT06205043"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06205043"
last_fetched: "2026-05-10T14:08:30.516Z"
source: "Parkinson's Pathways (curated)"
---
# Improve motor function using StimSearch

**Goal (in five words):** Improve motor function using StimSearch

**Official Title:** Enhancing Deep Brain Stimulation Programming for Parkinson's Disease: A Semi- Automatic Algorithm-Guided Approach Using StimSearch- A Double Blind Randomized Study

**Trial ID:** [NCT06205043](https://clinicaltrials.gov/study/NCT06205043)

## Key Facts

- **Phase:** NA
- **Status:** RECRUITING
- **Study Type:** INTERVENTIONAL
- **Sponsor:** Jaslok Hospital and Research Centre
- **Target Enrollment:** 30 participants
- **Start Date:** 2024-01-10
- **Completion Date:** 2026-02-01
- **Conditions:** Parkinson Disease
- **Interventions:** StimSearch programming algorithm software, Clinician based programming
- **Intervention Types:** DEVICE

## Summary For Families

The goal is to make deep brain stimulation programming more efficient and effective, so people with Parkinson's get better symptom control sooner and with fewer visits. The approach uses StimSearch, a semi-automatic algorithm-guided software that analyzes patient assessments and proposes DBS parameter settings, and the study will compare those algorithm suggestions to usual clinician-based programming in a double-blind, randomized way. They are looking for people with confirmed bilateral idiopathic Parkinson's who have significant motor symptoms off medication (UPDRS III ≥ 25), who improved by at least 30% on a pre-operative levodopa challenge, who can give informed consent, and who do not have major psychiatric conditions like substantial depression.

## Eligibility

- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

* Have a confirmed diagnosis of bilateral idiopathic Parkinson's disease
* Exhibit a UPDRS subset III score of ≥ 25 while in the preoperative medication off state
* Demonstrate an improvement of Parkinson's disease symptoms by ≥30% in the medication off state following a pre-operative levodopa challenge, as assessed by the UPDRS subset III score
* Possess the ability to comprehend the study's demands, treatment protocols, and procedures, and provide written informed consent before undergoing any study-specific tests or procedures

Exclusion Criteria:

* Patients with notable psychiatric conditions, including unrelated clinically substantial depression as assessed by the investigator, will be excluded from participation.
```

## Locations (1)

- Jaslok Hospital And Research Centre, Mumbai, Maharashtra, India _(19.0728, 72.8826)_
  - Sonali Vasnik, PhD — (CONTACT) — 02240173336 — sonali.neuromodulation.21@gmail.com
  - Paresh K Doshi, MCh — (PRINCIPAL_INVESTIGATOR)

## Central Contacts

- Paresh Doshi, MCh — (CONTACT) — +91 9820063854 — pareshkd@gmail.com

---

*Canonical: https://parkinsonspathways.com/trial/NCT06205043*  
*HTML version: https://parkinsonspathways.com/trial/NCT06205043*  
*Source data: https://clinicaltrials.gov/study/NCT06205043*