---
title: Acupuncture reduces tremor and slowness
nct_id: NCT06304285
phase: NA
status: RECRUITING
sponsor: The First Affiliated Hospital of University of Science and Technology of China
study_type: INTERVENTIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT06304285"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06304285"
last_fetched: "2026-05-10T14:08:12.316Z"
source: "Parkinson's Pathways (curated)"
---
# Acupuncture reduces tremor and slowness

**Goal (in five words):** Acupuncture reduces tremor and slowness

**Official Title:** A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis: a Single-center, Randomized, Double-blind Study

**Trial ID:** [NCT06304285](https://clinicaltrials.gov/study/NCT06304285)

## Key Facts

- **Phase:** NA
- **Status:** RECRUITING
- **Study Type:** INTERVENTIONAL
- **Sponsor:** The First Affiliated Hospital of University of Science and Technology of China
- **Target Enrollment:** 84 participants
- **Start Date:** 2024-03-01
- **Completion Date:** 2026-12-31
- **Conditions:** Parkinson's Disease, Chronic Appendicitis, Acupuncture
- **Interventions:** Acupuncture treatment, Sham acupuncture treatment
- **Intervention Types:** OTHER

## Summary For Families

The goal is to see whether acupuncture can help motor symptoms like slowness, tremor, and stiffness in people with Parkinson's disease who also have CT-confirmed chronic appendicitis. Participants are randomly assigned to real acupuncture or a sham procedure, with thin needles used at traditional points to stimulate peripheral nerves and potentially modulate brain circuits and inflammatory signals that affect movement. Because acupuncture is non-drug, people can remain on stable Parkinson's medications such as levodopa while in the study, so the effect is tested alongside usual treatment. The trial is looking for adults 40 to 70 years old with Parkinsonian bradykinesia plus tremor or rigidity, confirmed chronic appendicitis, normal clotting, and no major other neurological or systemic illnesses.

## Eligibility

- **Minimum age:** 40 Years
- **Maximum age:** 70 Years
- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

* Patients presenting with bradykinesia, combined with resting tremor and/or myotonia.
* Appendix CT suggested chronic appendicitis evaluated by two experienced experts.
* All subjects and their guardians give informed consent to the content of this study and sign informed consent.
* Normal coagulation function.
* If the patient had taken oral anti-PD drugs, it had been stable for at least 2 weeks at enrollment.

Exclusion Criteria:

* Treatment with dopamine blockers or dopamine depleters in doses and time courses consistent with drug-induced parkinsonism.
* Neuroimaging examination of presynaptic dopaminergic system function was normal.
* Patients who had suffered severe brain trauma or underwent complex craniotomy within 5 years prior to enrollment.
* Cognitive disorders that are not on the Parkinson's spectrum, such as Alzheimer's disease, frontotemporal dementia, and Niemann-Pick disease, have been diagnosed.
* People diagnosed with severe neuropsychiatric disorders (epilepsy, bipolar disorder, major depressive episode, etc.) according to DSM-V.
* Complicated with serious systemic diseases, disorders of consciousness, stroke, serious coronary heart disease, diabetes, liver and kidney diseases, and serious visual and hearing disorders.
* Patients with severe organic or functional dysphagia;Those who were deemed by the researcher to be unable to complete the visit and auxiliary examination as required by the study protocol.
```

## Locations (1)

- The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui, China _(31.8639, 117.2808)_
  - Yuhua Chen, M.M.S. — (CONTACT) — +8615955236270 — yh1215@mail.ustc.edu.cn
  - Chao Han, M.D. — (CONTACT) — +8615255629713 — chaohan@ustc.edu.cn

## Central Contacts

- Yuhua Chen, M.M.S. — (CONTACT) — +8615955236270 — yh1215@mail.ustc.edu.cn
- Chao Han, M.D. — (CONTACT) — +8615255629713 — 15255629713@193.com

---

*Canonical: https://parkinsonspathways.com/trial/NCT06304285*  
*HTML version: https://parkinsonspathways.com/trial/NCT06304285*  
*Source data: https://clinicaltrials.gov/study/NCT06304285*