---
title: Reduce Parkinson fatigue through exercise
nct_id: NCT06324422
phase: NA
status: RECRUITING
sponsor: University of Aarhus
study_type: INTERVENTIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT06324422"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06324422"
last_fetched: "2026-05-10T14:05:37.316Z"
source: "Parkinson's Pathways (curated)"
---
# Reduce Parkinson fatigue through exercise

**Goal (in five words):** Reduce Parkinson fatigue through exercise

**Official Title:** Can High-intensity Exercise be Used to Treat Fatigue in Parkinson´s Disease?

**Trial ID:** [NCT06324422](https://clinicaltrials.gov/study/NCT06324422)

## Key Facts

- **Phase:** NA
- **Status:** RECRUITING
- **Study Type:** INTERVENTIONAL
- **Sponsor:** University of Aarhus
- **Target Enrollment:** 94 participants
- **Start Date:** 2024-04-24
- **Completion Date:** 2026-12-01
- **Conditions:** Parkinson's Disease
- **Interventions:** Aerobic exercise intervention, Resistance exercise intervention
- **Intervention Types:** OTHER

## Summary For Families

Researchers at the University of Aarhus are testing whether high-intensity exercise can reduce the persistent fatigue many people with Parkinson's face. Participants do either a high-intensity aerobic program to boost cardiovascular fitness and endurance, or a high-intensity resistance program to build muscle strength so everyday tasks use less energy; both approaches aim to raise overall energy capacity and physical resilience. The trial is enrolling people 40 or older with idiopathic Parkinson's who have been on stable medication for six months, are at Hoehn and Yahr stage 3 or lower, and can travel to sessions, while excluding those already doing high-intensity exercise more than twice weekly or with major medical issues, cognitive problems, depression, or alcohol abuse.

## Eligibility

- **Minimum age:** 40 Years
- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

* Minimum 40 years
* Diagnosed with Idiopathic Parkinsons disease
* Stable in medical treatment for six month
* Able to transport themselves to and from exercise and testing sessions (with or without assistance)
* H\&Y score of three or lower

Exclusion criteria:

* Performing high-intensity exercise more than two times per week
* Significant medical comorbidities such as cardiovascular, respiratory, orthopedic, metabolic, or other neurological disorders
* Cognitive dysfunction that prevents following or understanding instructions related to training and testing (answering questionnaires)
* Known depression or alcohol abuse
```

## Locations (1)

- Exercise Biology, Dep. of Public Health, Aarhus University, Aarhus, Central Jutland, Denmark _(56.1567, 10.2108)_
  - Cecilie Thrue, PhD student — (CONTACT) — 004520768102 — ceth@ph.au.dk
  - Cecilie Thrue, PhD student — (PRINCIPAL_INVESTIGATOR)

## Central Contacts

- Cecilie Thrue, PhD student — (CONTACT) — +4520768102 — ceth@ph.au.dk
- Ulrik Dalgas, Professor — (CONTACT) — dalgas@ph.au.dk

---

*Canonical: https://parkinsonspathways.com/trial/NCT06324422*  
*HTML version: https://parkinsonspathways.com/trial/NCT06324422*  
*Source data: https://clinicaltrials.gov/study/NCT06324422*