Reduce freezing during first steps
- Trial ID
- NCT06363071
- Official Title
- Gait-initiation Related APA Training in Individuals With Parkinson Disease -Explicit Training and Paired Associative Stimulation(PAS) Priming
- Goal
- Reduce freezing during first steps
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Chang Gung University
- Study Type
- INTERVENTIONAL
- Enrollment
- 100 participants
- Conditions
- Parkinson Disease
- Interventions
- Weight shift training and APA feedback, Paired associative stimulation
Plain-Language Summary
Helping people with Parkinson's start walking more smoothly, this trial targets the small balance and weight-shift problems that make the first step hard and can lead to freezing or falls. It combines explicit weight-shift and anticipatory postural adjustment training with real-time feedback, plus paired associative stimulation, a noninvasive technique that pairs brief nerve pulses with brain stimulation to strengthen the motor pathways that control stepping. The interventions are rehabilitation and neuromodulation, not drugs, so they do not directly change levodopa dosing. Adults aged 20 and up with a clinical diagnosis of Parkinson disease are eligible, while people with leg musculoskeletal injuries, osteoporosis, or other peripheral or central nervous system diseases are excluded; about 100 participants will be enrolled.
Locations
- Chang Gung University, Taoyuan District, Taiwan
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Weight shift training and APA feedback. Helping people with Parkinson's start walking more smoothly, this trial targets the small balance and weight-shift problems that make the first step hard and can lead to freezing or falls. It combines explicit weight-shift and anticipatory postural adjustment training with real-time feedback, plus paired associative stimulation, a noninvasive technique that pairs brief nerve pulses with brain stimulation to strengthen the motor pathways that control stepping. The interventions are rehabilitation and neuromodulation, not drugs, so they do not directly change levodopa dosing. Adults aged 20 and up with a clinical diagnosis of Parkinson disease are eligible, while people with leg musculoskeletal injuries, osteoporosis, or other peripheral or central nervous system diseases are excluded; about 100 participants will be enrolled.
- Who can participate?
- Participants must be at least 20 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 2 years and 10 months.