---
title: Assess taste function in Parkinsons
nct_id: NCT06439355
phase: NA
status: RECRUITING
sponsor: Centre Hospitalier Universitaire Dijon
study_type: INTERVENTIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT06439355"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06439355"
last_fetched: "2026-05-10T14:06:15.217Z"
source: "Parkinson's Pathways (curated)"
---
# Assess taste function in Parkinsons

**Goal (in five words):** Assess taste function in Parkinsons

**Official Title:** Single-center Study of Gustation in Idiopathic Parkinson's Disease and Lewy Body Disease Using Gustatory Evoked Potential Analysis

**Trial ID:** [NCT06439355](https://clinicaltrials.gov/study/NCT06439355)

## Key Facts

- **Phase:** NA
- **Status:** RECRUITING
- **Study Type:** INTERVENTIONAL
- **Sponsor:** Centre Hospitalier Universitaire Dijon
- **Target Enrollment:** 66 participants
- **Start Date:** 2024-05-27
- **Completion Date:** 2026-05
- **Conditions:** Idiopathic Parkinson's Disease and Lewy Body Disease
- **Interventions:** Fasting blood test, Subject interview, Motor assessment, Neurocognitive assessment, Nutritional assessment, Taste tests
- **Intervention Types:** BIOLOGICAL, OTHER

## Summary For Families

The team is investigating how taste perception and the brain's electrical responses to taste are altered in people with idiopathic Parkinson's disease and Lewy body disease, to help explain common changes in appetite, weight and taste. Participants do taste tests while clinicians record gustatory evoked potentials, which are the electrical signals the nervous system makes in response to taste, plus fasting blood work and motor, cognitive and nutritional assessments to connect taste signal changes with disease features. Adults 18 and older can join, including people with diagnosed IPD or probable/possible LBD and healthy volunteers, and everyone must fast over 2 hours and have BMI under 30; excluded are folks with diabetes, pacemakers, heavy smoking (>4 cigarettes/day), pregnancy, very low cognitive scores (MMSE <15 or MoCA <10), or medications that affect taste. The single-center study in Dijon aims to enroll about 66 participants.

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

Healthy volunteers:

* Person who has given written consent
* Adult
* Enrolled in the national register of healthy volunteers
* Fasting \> 2 hours before PEG measurement
* Body Mass Index (BMI) \< 30 kg/m².
* No cognitive complaints and normal neurological assessment

Patients with idiopathic Parkinson's disease:

* Person who has given written consent
* Adult
* Fasting \> 2 hours before PEG measurement
* Body Mass Index (BMI) \< 30 kg/m².
* Diagnostic criteria for established or probable IPD

Patients with Lewy body disease:

* Person who has given written consent
* Adult
* Fasting \> 2 hours prior to PEG measurement
* Body Mass Index (BMI) \< 30 kg/m².
* Diagnostic criteria for probable or possible LBD

Exclusion Criteria:

* Non-affiliated to national health insurance
* Person under legal protection (curatorship, guardianship)
* Person subject to a court order
* Pregnant, parturient or breast-feeding women
* Major unable to give consent
* MMSE score \< 15 and/or MoCA \< 10
* Known infection with COVID-19 in the 6 months prior to inclusion
* Active smoker (\> 4 cigarettes per day on a regular basis)
* Subject with pacemaker (contraindication for bioelectrical impedancemetry)
* Diabetic (type 1 or type 2)
* Taking medication (in progress at the time of the study) that interferes with gustation
```

## Locations (1)

- Chu Dijon Bourgogne, Dijon, France _(47.3134, 5.0139)_
  - Vincent SCHNEIDER — (CONTACT) — 03.80.29.30.89 — vincent.schneider@chu-dijon.fr

## Central Contacts

- Vincent SCHNEIDER — (CONTACT) — 03.80.29.30.89 — vincent.schneider@chu-dijon.fr

---

*Canonical: https://parkinsonspathways.com/trial/NCT06439355*  
*HTML version: https://parkinsonspathways.com/trial/NCT06439355*  
*Source data: https://clinicaltrials.gov/study/NCT06439355*