---
title: Measure emotional response to music
nct_id: NCT06688968
phase: NA
status: RECRUITING
sponsor: University Hospital, Montpellier
study_type: INTERVENTIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT06688968"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06688968"
last_fetched: "2026-05-10T14:06:44.816Z"
source: "Parkinson's Pathways (curated)"
---
# Measure emotional response to music

**Goal (in five words):** Measure emotional response to music

**Official Title:** Observational Pilot Study of Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease. What Are the Effects of Mnestic or Hedonic Impairment on Emotion, Reminiscence and Musical Enjoyment

**Trial ID:** [NCT06688968](https://clinicaltrials.gov/study/NCT06688968)

## Key Facts

- **Phase:** NA
- **Status:** RECRUITING
- **Study Type:** INTERVENTIONAL
- **Sponsor:** University Hospital, Montpellier
- **Target Enrollment:** 120 participants
- **Start Date:** 2025-02-04
- **Completion Date:** 2025-12-01
- **Conditions:** Alzheimer Disease, Early Onset, Parkinsons Disease with Dementia, Non Pharmacological Intervention
- **Interventions:** neuropsychologist interview, questionnaire
- **Intervention Types:** BEHAVIORAL

## Summary For Families

The goal is to figure out how memory loss or a reduced ability to feel pleasure in Parkinson’s disease with dementia (and early Alzheimer’s) changes emotional reactions, reminiscence, and enjoyment of music, information that can help shape music-based support. The approach uses structured neuropsychological interviews and questionnaires to map cognitive and hedonic profiles and to measure emotional and memory responses to musical engagement, so no drugs or devices are given. The study is looking for French-speaking adults age 60 and up who live at home with a relative, have an MMSE score of 20 or higher, and a diagnosis of idiopathic Parkinson’s disease or probable Alzheimer’s disease; people with major non-degenerative neurological or psychiatric disorders, untreated hearing loss, inability to consent, or recent stroke/head trauma are excluded. The pilot plans to enroll about 120 participants.

## Eligibility

- **Minimum age:** 60 Years
- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

General inclusion criteria:

* 60 years and older
* French-speaking and volunteering for the study
* Living at home with a relative

Alzheimer's disease inclusion criteria:

* Biological diagnosis of probable Alzheimer's disease according to NINCDS-ADRDA criteria (McKhann et al., 1984)
* MMSE greater than or equal to 20

Inclusion criteria Parkinson's disease :

* Diagnosis of Idiopathic Parkinson's disease
* MMSE greater than or equal to 20

Exclusion Criteria:

* No known neurological pathologies (epilepsy and other non-degenerative CNS diseases) or psychiatric disorders (chronic psychosis and psychotic episodes)
* Autistic disorders
* History of stroke or head trauma
* Unstable medical condition (cancer)
* Subject unable to read and/or write
* Hearing impairment without hearing aids
* Refusal of consent after information
* Persons unable to give consent, research carried out in emergency situations, etc.)
* Non-affiliation with a social security scheme
* Person deprived of liberty (by judicial or administrative decision, or forced hospitalization)
* Person under legal protection (guardianship, curatorship, legal protection)
* Person participating in another research project with an exclusion period still in progress
```

## Locations (3)

- Montpellier Seniors' Association, Montpellier, Hérault, France _(43.6109, 3.8763)_
  - Mikaël Guenguelou, PhD — (CONTACT) — 06.04.45.37.94. — mikael.genguelou@univ-montp3.fr
- CHU de Montpellier - CEPMo, Montpellier, Hérault, France _(43.6109, 3.8763)_
  - Mahmoud CHARIF, MD — (CONTACT) — 0467337413 — m-charif@chu-montpellier.fr
- CHU de Montpellier - CMRR, Montpellier, Hérault, France _(43.6109, 3.8763)_
  - Karim BENNYS, MD — (CONTACT) — 04.67.33.60.29 — k-bennys@chu-montpellier.fr

## Central Contacts

- Mikaël Genguelou, PhD — (CONTACT) — 06.04.45.37.94. — mikael.genguelou@univ-montp3.fr
- KARIM BENNYS, MD — (CONTACT) — 04.67.33.72.32 — k-bennys@chu-montpellier.fr

---

*Canonical: https://parkinsonspathways.com/trial/NCT06688968*  
*HTML version: https://parkinsonspathways.com/trial/NCT06688968*  
*Source data: https://clinicaltrials.gov/study/NCT06688968*