---
title: Detect internal tremors using oscillometry
nct_id: NCT06885541
phase: NA
status: RECRUITING
sponsor: University Hospital, Toulouse
study_type: INTERVENTIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT06885541"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06885541"
last_fetched: "2026-05-10T14:04:49.316Z"
source: "Parkinson's Pathways (curated)"
---
# Detect internal tremors using oscillometry

**Goal (in five words):** Detect internal tremors using oscillometry

**Official Title:** Detection of Internal Tremors by Oscillometry in Parkinson's Patient : a Pilot Study

**Trial ID:** [NCT06885541](https://clinicaltrials.gov/study/NCT06885541)

## Key Facts

- **Phase:** NA
- **Status:** RECRUITING
- **Study Type:** INTERVENTIONAL
- **Sponsor:** University Hospital, Toulouse
- **Target Enrollment:** 60 participants
- **Start Date:** 2026-02-10
- **Completion Date:** 2027-05-10
- **Conditions:** Parkinson Disease
- **Interventions:** Detection of objective internal tremors
- **Intervention Types:** DIAGNOSTIC_TEST

## Summary For Families

The goal is to find an objective way to detect "internal tremors," the shaking sensations some people with Parkinson's feel even when no visible tremor appears. The team uses oscillometry, basically wearable accelerometers, to record tiny internal vibrations while people are in the OFF medication state so the signals are measured without the immediate effects of levodopa; the test only records data, it does not change your treatment. This is a pilot comparison with age and sex matched healthy volunteers to see if the device can reliably pick up those hidden tremors. Adults 18 to 80 with idiopathic Parkinson's, a Mini Mental State score of 25 or higher, Hoehn and Yahr stage 3 or less when OFF, and who can stand and walk unaided are eligible, while people with DBS, pump therapies, major gait or neurological problems, or certain tremor-causing conditions are excluded.

## Eligibility

- **Minimum age:** 18 Years
- **Maximum age:** 80 Years
- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

(For the experimental group)

* Patient with idiopathic parkinson's disease
* Mini Mental State Evaluation score above or equal to 25
* Hoehn and Yahr scale score of ≤3 in the OFF phase, with postural stability allowing the patient to stand unaided for 1 minute.
* Able to walk unassisted
* Willing to undergo accelerometry in the OFF state

(For the control group)

* Healthy volunteer subjects matched for age (+/- 5 years) and sex
* Mini Mental State Evaluation score above or equal to 25

Exclusion Criteria:

(For the experimental group)

* Patients with an atypical parkinsonian syndrome
* Patients unable to walk or stand for more than one minute in the off state
* Parkinson's patients treated with deep brain stimulation, apomorphine pump, or duodopa intestinal infusion, and foslevodopa
* Pregnant patients
* Major osteoarticular problems
* Neurological condition that may affect gait

(For the control group)

* Participants with significant gait impairment (osteoarticular disorder)
* Those with a neurological disease that, in the investigator's judgment, may interfere with the study's outcome measure
* Participants with a clinical tremor that may interfere with the measurement of the primary outcome (e.g., essential tremor, thyroid disease, or tremors induced by medication)
* Pregnant participants
```

## Locations (1)

- Purpan Hospital, Toulouse, Occitanie, France _(43.6043, 1.4437)_
  - Ana Raquel PINHEIRO BARBOSA — (CONTACT) — 0561779930 — pinheirobarbosa.ar@chu-toulouse.fr

## Central Contacts

- Ana Raquel PINHEIRO BARBOSA — (CONTACT) — (+33) 05.61.77.99.30 — pinheirobarbosa.ar@chu-toulouse.fr

---

*Canonical: https://parkinsonspathways.com/trial/NCT06885541*  
*HTML version: https://parkinsonspathways.com/trial/NCT06885541*  
*Source data: https://clinicaltrials.gov/study/NCT06885541*