---
title: Reduce freezing episodes during walking
nct_id: NCT06911229
phase: NA
status: RECRUITING
sponsor: University of Florida
study_type: INTERVENTIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT06911229"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT06911229"
last_fetched: "2026-05-10T14:07:39.116Z"
source: "Parkinson's Pathways (curated)"
---
# Reduce freezing episodes during walking

**Goal (in five words):** Reduce freezing episodes during walking

**Official Title:** Neurophysiology of Locomotor Adaptation and Freezing of Gait in Parkinson's Disease

**Trial ID:** [NCT06911229](https://clinicaltrials.gov/study/NCT06911229)

## Key Facts

- **Phase:** NA
- **Status:** RECRUITING
- **Study Type:** INTERVENTIONAL
- **Sponsor:** University of Florida
- **Target Enrollment:** 60 participants
- **Start Date:** 2025-08-01
- **Completion Date:** 2028-12-31
- **Conditions:** Parkinson Disease
- **Interventions:** Deep Brain Stimulation (DBS)
- **Intervention Types:** DEVICE

## Summary For Families

The goal is to pinpoint how the brain circuits that control walking break down in Parkinson's, especially during freezing of gait and when people have to adapt their steps. The team will study people who already have chronically implanted, optimized deep brain stimulation, recording brain signals while participants walk so researchers can see how the electrical stimulation, which sends continuous pulses to motor circuits to normalize abnormal signals and improve movement, relates to freezing and gait adaptation. They are enrolling adults 18 to 80 with a confirmed idiopathic Parkinson's diagnosis who have had stable DBS for at least six months, are ambulatory without walking aids, and do not have dementia or other neurologic conditions like atypical parkinsonism.

## Eligibility

- **Minimum age:** 18 Years
- **Maximum age:** 80 Years
- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

* consensus diagnosis of idiopathic PD by fellowship trained movement disorders neurologists at the Normal Fixel Institute of Neurological Diseases;
* chronically stable DBS, defined as having had DBS for at least 6 months in duration with optimized DBS settings;
* Age between 18 - 80 years old per the FDA data sheet for PD DBS;
* no dementia according to the clinical diagnostic criteria for PD dementia;
* ambulatory without the use of walking aids, or another person's assistance.

Exclusion Criteria:

* other previous neurological surgery;
* suspicion of other neurologic diagnoses such as atypical parkinsonism, or Alzheimer's disease.
```

## Locations (1)

- University of Florida, Gainesville, Florida, United States _(29.6516, -82.3248)_
  - Julia Choi — (CONTACT)

## Central Contacts

- Julia Choi, Ph.D. — (CONTACT) — 3522941720 — juliachoi@ufl.edu

---

*Canonical: https://parkinsonspathways.com/trial/NCT06911229*  
*HTML version: https://parkinsonspathways.com/trial/NCT06911229*  
*Source data: https://clinicaltrials.gov/study/NCT06911229*