---
title: Reduce constipation using dietitian guidance
nct_id: NCT07213856
phase: NA
status: RECRUITING
sponsor: Hospital de Clinicas de Porto Alegre
study_type: INTERVENTIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT07213856"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT07213856"
last_fetched: "2026-06-16T14:00:28.222Z"
source: "Parkinson's Pathways (curated)"
---
# Reduce constipation using dietitian guidance

**Goal (in five words):** Reduce constipation using dietitian guidance

**Official Title:** Nutritional Intervention for Constipation Symptoms in Patients With Parkinson's Disease: A Randomized Clinical Trial

**Trial ID:** [NCT07213856](https://clinicaltrials.gov/study/NCT07213856)

## Key Facts

- **Phase:** NA
- **Status:** RECRUITING
- **Study Type:** INTERVENTIONAL
- **Sponsor:** Hospital de Clinicas de Porto Alegre
- **Target Enrollment:** 54 participants
- **Start Date:** 2026-04-02
- **Completion Date:** 2027-06
- **Conditions:** Parkinsons Disease (PD), Constipation - Functional
- **Interventions:** Dietitian-Guided Nutritional Intervention
- **Intervention Types:** BEHAVIORAL

## Summary For Families

Researchers want to know whether a dietitian-guided eating plan can increase weekly bowel movements and ease constipation in people with Parkinson's, and whether it changes gut bacteria, what people eat, and overall nutritional status. Participants follow a personalized diet from a dietitian and have follow-up sessions for three months, while a control group receives general dietary advice after the study; bowel habits, gut bacteria, diet quality, and nutrition are measured at the start, midpoint, and end. Adults with Parkinson's who have functional constipation and have been on a stable levodopa dose for at least three months are eligible, while people with atypical parkinsonism, more advanced disease, dementia or severe medical conditions, recent antibiotic or probiotic use, recent continuous laxative or opioid use, severe swallowing problems, recent nutritional care, or certain gastrointestinal or major illnesses are excluded.

## What This Actually Involves

**Placebo** _(From the protocol)_: This trial has a group that receives no study treatment (you would continue your usual care) alongside the treatment group. Because assignment is random, you have about a 1 in 2 chance (roughly 50%) of being in the no-treatment group, assuming the groups are filled equally. Ask the coordinator to confirm the exact assignment ratio.

**Visits** _(From the protocol)_: Participants will have follow-up sessions with the dietitian for 3 months and complete assessments at baseline, midpoint, and end of the intervention.
  > "* Participate in follow-up sessions with the dietitian for 3 months
* Complete assessments at baseline, midpoint, and end of the intervention to evaluate bowel function, constipation symptoms, gut microbiota, nutritional status, and diet quality"

**Procedures** _(Ask the coordinator)_: Ask the coordinator what tests and procedures are involved, for example blood draws, scans, or questionnaires, and whether any are uncomfortable or invasive.

**Washout** _(Ask the coordinator)_: Ask the coordinator whether you would need to stop or pause any of your current medications before or during the study (a washout period), and for how long.

**Travel & reimbursement** _(Ask the coordinator)_: Ask the coordinator whether travel, parking, or your time is reimbursed or compensated, and what is covered.

_Fields marked “From the protocol” come from the trial's registry record or quoted protocol text. Fields marked “Ask the coordinator” are not reliably available and should be confirmed directly._

## Eligibility

- **Minimum age:** 18 Years
- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

* Adults with a previous diagnosis of Parkinson's disease
* On a stable dose of levodopa for at least 3 months
* Diagnosis of Functional Constipation by the Rome IV protocol

Exclusion Criteria:

* Diagnosis of atypical or secondary parkinsonism
* Hoehn and Yahr stage greater than 2
* Presence of severe neurological or psychiatric disorders that impair the ability to participate in study procedures
* Previous diagnosis of dementia
* Presence of comorbidities such as active cancer, chronic obstructive pulmonary disease (COPD), heart failure, and/or chronic kidney disease
* History of gastrointestinal cancers, inflammatory bowel diseases, or surgeries involving the gastrointestinal tract
* Constipation secondary to clinical conditions such as hypothyroidism or diabetes mellitus
* Use of opioids
* Use of probiotics or antibiotics in the past 8 weeks
* Continuous use of laxatives in the past 8 weeks
* Presence of severe dysphagia according to the Functional Oral Intake Scale (FOIS)
* Individuals receiving enteral or parenteral nutrition
* Individuals under nutritional follow-up in the past 3 months
```

## Locations (1)

- Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Rio Grande do Sul, Brazil _(-30.0328, -51.2302)_
  - Maira Rozenfeld Olchik, PhD, (CONTACT), +55 (51) 33083020, molchik@hcpa.edu.br
  - Juliana Heitich Brendler, Msc, (SUB_INVESTIGATOR)

## Central Contacts

- Maira Rozenfeld Olchik, PhD, (CONTACT), +55 (51) 33083020, molchik@hcpa.edu.br

---

*Canonical: https://parkinsonspathways.com/trial/NCT07213856*  
*HTML version: https://parkinsonspathways.com/trial/NCT07213856*  
*Source data: https://clinicaltrials.gov/study/NCT07213856*