---
title: Predict falls due to freezing
nct_id: NCT07386015
status: RECRUITING
sponsor: Tianjin Huanhu Hospital
study_type: OBSERVATIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT07386015"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT07386015"
last_fetched: "2026-05-10T14:07:48.216Z"
source: "Parkinson's Pathways (curated)"
---
# Predict falls due to freezing

**Goal (in five words):** Predict falls due to freezing

**Official Title:** FREEZE-Path Cohort: Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG)

**Trial ID:** [NCT07386015](https://clinicaltrials.gov/study/NCT07386015)

## Key Facts

- **Status:** RECRUITING
- **Study Type:** OBSERVATIONAL
- **Sponsor:** Tianjin Huanhu Hospital
- **Target Enrollment:** 700 participants
- **Start Date:** 2026-02-28
- **Completion Date:** 2029-12-31
- **Conditions:** Freezing of Gait, Parkinson's Disease, Parkinsonism, Vascular Parkinsonism, Idiopathic Normal Pressure Hydrocephalus (INPH)
- **Interventions:** Observational Data Collection
- **Intervention Types:** OTHER

## Summary For Families

The goal is to unravel why freezing of gait happens and how different causes and movement patterns predict who gets worse, so clinicians can identify distinct FOG subtypes and better predict outcomes. To do that, researchers will collect observational data from up to 700 people, including gait and balance tests, video and speech recordings, and clinical measures, then map etiology, phenotype, and outcome links without testing a treatment. Adults 30 to 85 with Parkinson's disease or related parkinsonian disorders who have freezing or other gait or balance problems and can complete assessments and give consent are eligible, while people with very severe dementia (MMSE < 10), major recent medical events, severe psychiatric or medical issues affecting gait safety, inability to follow up, or refusal of video/speech recording are excluded.

## Eligibility

- **Minimum age:** 30 Years
- **Maximum age:** 85 Years
- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

1. Age 30-85 years
2. Presence of freezing of gait or non-freezing gait or balance impairment
3. Diagnosis of Parkinson's disease or related parkinsonian disorders according to established international criteria (including PD, PSP, MSA, DLB, CBD, vascular parkinsonism, or idiopathic normal pressure hydrocephalus)
4. Ability to complete gait and balance assessment tasks independently or with assistance
5. Ability and willingness to provide written informed consent

Exclusion Criteria:

1. Severe dementia (Mini-Mental State Examination score \< 10)
2. Severe psychiatric disorders interfering with study participation
3. Severe cardiopulmonary, musculoskeletal, or other medical conditions significantly affecting gait safety
4. Stroke, fracture, or other major medical events within the past 3 months
5. Inability to comply with follow-up procedures
6. Refusal of video or speech data collection
```

## Locations (1)

- Tianjin Huanhu Hospital, Tianjin, Tianjin Municipality, China _(39.1422, 117.1767)_
  - Peipei Liu, MD — (CONTACT) — 86-13512204476 — pddoctorpipi2021@163.com

## Central Contacts

- Peipei Liu, MD — (CONTACT) — 86-13512204476 — pddoctorpipi2021@163.com

---

*Canonical: https://parkinsonspathways.com/trial/NCT07386015*  
*HTML version: https://parkinsonspathways.com/trial/NCT07386015*  
*Source data: https://clinicaltrials.gov/study/NCT07386015*