---
title: Improve walking speed and balance
nct_id: NCT07589296
phase: NA
status: RECRUITING
sponsor: Kanuni Sultan Suleyman Training and Research Hospital
study_type: INTERVENTIONAL
canonical_url: "https://parkinsonspathways.com/trial/NCT07589296"
clinicaltrials_gov: "https://clinicaltrials.gov/study/NCT07589296"
last_fetched: "2026-05-15T14:00:16.332Z"
source: "Parkinson's Pathways (curated)"
---
# Improve walking speed and balance

**Goal (in five words):** Improve walking speed and balance

**Official Title:** Comparative Effects of Robot-Assisted Gait Training and Quadriceps Neuromuscular Electrical Stimulation Added to Standard Exercise Rehabilitation on Balance, Gait, Disease Severity, and Quadriceps Muscle Adaptations in Patients With Parkinson Disease: A Prospective Randomized Assessor-Blinded Clinical Trial

**Trial ID:** [NCT07589296](https://clinicaltrials.gov/study/NCT07589296)

## Key Facts

- **Phase:** NA
- **Status:** RECRUITING
- **Study Type:** INTERVENTIONAL
- **Sponsor:** Kanuni Sultan Suleyman Training and Research Hospital
- **Target Enrollment:** 40 participants
- **Start Date:** 2026-04-15
- **Completion Date:** 2026-04-15
- **Conditions:** Parkinson Disease (PD)
- **Interventions:** Quadriceps Neuromuscular Electrical Stimulation (NMES), robot -assisted gait training
- **Intervention Types:** OTHER, DEVICE

## Summary For Families

Researchers are comparing whether adding robot-assisted gait training or electrical stimulation of the quadriceps to standard exercise rehab does a better job of improving balance, walking, overall Parkinson's severity, and changes in thigh muscle. The robot guides and supports repeated, task-specific walking to retrain gait and balance, while neuromuscular electrical stimulation sends small pulses to make the quadriceps contract, strengthening the muscle and improving activation; both are delivered on top of usual rehab exercises. The trial is looking for people aged 40 to 80 with mild to moderate Parkinson's (Hoehn and Yahr stage II,III) who can walk independently, are on stable medications, can follow instructions, and do not have severe cognitive, cardiovascular, or musculoskeletal problems or implanted electronic devices like pacemakers.

## Eligibility

- **Minimum age:** 40 Years
- **Maximum age:** 80 Years
- **Sex:** ALL

### Full Criteria

```
Inclusion Criteria:

* Diagnosis of Parkinson's disease according to established clinical criteria
* Age between 40 and 80 years
* Hoehn and Yahr stage II-III
* Ability to walk independently with or without assistive devices
* Stable medical treatment for at least 4 weeks prior to study enrollment
* Ability to understand and follow instructions
* Willingness to participate and provide written informed consent

Exclusion Criteria:

* Severe cognitive impairment or inability to follow instructions
* Hoehn and Yahr stage IV-V Parkinson's disease
* Severe musculoskeletal disorders affecting gait (e.g., advanced osteoarthritis, recent fracture)
* History of lower extremity surgery within the last 6 months
* Severe cardiovascular or respiratory disease limiting exercise participation
* Presence of other neurological disorders affecting mobility (e.g., stroke, multiple sclerosis)
* Contraindications to electrical stimulation (e.g., pacemaker, implanted electronic devices)
* Skin lesions or infections at electrode placement sites
* Participation in another structured rehabilitation program within the last 3 months
```

## Locations (1)

- Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey, Küçükçekmece, Istanbul, Turkey (Türkiye) _(40.9910, 28.7712)_
  - Dilek Ün Oğuzhanasiltürk, MD — (CONTACT) — +905056367184 — dilekunoguzhan@gmail.com

## Central Contacts

- dilek Ün Oğuzhanasiltürk, MD — (CONTACT) — +90 5056367184 — dilekunoguzhan@gmail.com

---

*Canonical: https://parkinsonspathways.com/trial/NCT07589296*  
*HTML version: https://parkinsonspathways.com/trial/NCT07589296*  
*Source data: https://clinicaltrials.gov/study/NCT07589296*