LSVT-LOUD Therapy for Parkinson's (NCT07730073)
Testing speech therapy for loudness
- Trial ID
- NCT07730073
- Official Title
- The Effect of Lee Silverman Voice Therapy-LOUD (LVST-LOUD) Therapy Method on Voice and Speech Skills and Examination of Therapy Experiences in Turkish-Speaking Individuals With Parkinson's Disease
- Goal
- Testing speech therapy for loudness
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Atlas University
- Study Type
- INTERVENTIONAL
- Enrollment
- 24 participants
- Conditions
- Parkinson's Disease (PD)
- Interventions
- LSVT-LOUD Therapy
Summary For Families
Researchers are testing whether Lee Silverman Voice Therapy, called LSVT-LOUD, can raise vocal loudness and make speech clearer for Turkish-speaking people with Parkinson's, because softer, harder-to-understand speech often hurts quality of life. The therapy is an intensive, one-on-one program done in Turkish, with 60-minute sessions four times a week for four weeks that focus on high-effort speaking through exercises like sustained sounds, pitch glides, louder-speech drills, stepwise practice from words to conversation, and daily homework to carry the gains into real life. Therapists use sound feedback to help people relearn how loud "loud" should feel so the louder voice becomes part of everyday speaking. Eligible participants are native Turkish speakers age 40 to 80 with mild to moderate Parkinson's (stages 1 to 3), noticeable voice or speech problems, enough thinking ability to take part (a common cognitive screen score of 24 or higher), and a stable medication plan; people with other major brain disorders, untreated hearing loss, dementia, recent laryngeal surgery or recent deep brain stimulation, or recent intensive speech therapy are not eligible.
Eligibility at a Glance
Key requirements found in this trial's official criteria, in plain language. Only what the listing states is shown; the study team makes the final call.
- Disease stage: Hoehn and Yahr stage 1 to 3
- Deep brain stimulation: Cannot join after DBS surgery (deep brain stimulation) (criteria text: "recent surgery: history of laryngeal surgery or deep brain stimulation (dbs) within the last 6 months")
- Thinking test (MMSE): MMSE memory and thinking score of at least 24 (criteria text: ", mini-mental state examination (mmse) score >= 24)")
Locations
- Atlas University, Kâğıthane, Istanbul, Turkey (Türkiye)
Making Contact: How to Call This Study Site
Who to ask for
Ask for the study coordinator. Some sites call this person the research coordinator. They are the right person for questions about joining a study. If you reach a front desk or a doctor's office scheduler, ask them to connect you with the research team for this study.
What to say
It is fine to read this out loud, word for word:
Hello, my name is ____. I am calling about a Parkinson's study at your site. The study number is NCT07730073. It is the one about "Testing speech therapy for loudness". Could I speak with the study coordinator about taking part?
If you are calling for a family member, use their name and mention that you help with their care.
What they will ask you
- The year of diagnosis
- Current medications and their doses
- Other health conditions
- Any procedures already done, such as deep brain stimulation (DBS)
- How far you are able to travel for study visits
- Whether a care partner can come to visits with you
What to have ready
- A written list of current medications and doses
- Your neurologist's name and phone number
- The diagnosis date. The year is enough.
- A recent visit summary from the neurologist, if you have one
What to ask them
- How many visits are there, and how long does each visit take? The listing already answers this: You will attend individual therapy sessions four times per week for four weeks, each session lasting 60 minutes. Ask the coordinator to confirm it still applies.
- Is travel, parking, or my time reimbursed?
- Is there a placebo group, and what is my chance of being in it? The listing already answers this: This trial has a group that receives no study treatment (you would continue your usual care) alongside the treatment group. Because assignment is random, you have about a 1 in 2 chance (roughly 50%) of being in the no-treatment group, assuming the groups are filled equally. Ask the coordinator to confirm the exact assignment ratio.
- Would I need to stop or pause any of my current medications?
- What happens when the study ends? Could I stay on the treatment if it helps?
What to expect
- Expect to wait a few days for a callback. A week is common. Calling or emailing again after that is fine and normal.
- Many callers do not end up joining. Screening out is common and is not a judgment about you or your health.
- Asking questions commits you to nothing. You can stop the process at any point.
Frequently Asked Questions
- What is this trial testing?
- This trial is studying LSVT-LOUD Therapy. Researchers are testing whether Lee Silverman Voice Therapy, called LSVT-LOUD, can raise vocal loudness and make speech clearer for Turkish-speaking people with Parkinson's, because softer, harder-to-understand speech often hurts quality of life. The therapy is an intensive, one-on-one program done in Turkish, with 60-minute sessions four times a week for four weeks that focus on high-effort speaking through exercises like sustained sounds, pitch glides, louder-speech drills, stepwise practice from words to conversation, and daily homework to carry the gains into real life. Therapists use sound feedback to help people relearn how loud "loud" should feel so the louder voice becomes part of everyday speaking. Eligible participants are native Turkish speakers age 40 to 80 with mild to moderate Parkinson's (stages 1 to 3), noticeable voice or speech problems, enough thinking ability to take part (a common cognitive screen score of 24 or higher), and a stable medication plan; people with other major brain disorders, untreated hearing loss, dementia, recent laryngeal surgery or recent deep brain stimulation, or recent intensive speech therapy are not eligible.
- Who can participate?
- Participants must be between 40 Years and 80 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 9 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This trial has a group that receives no study treatment (you would continue your usual care) alongside the treatment group. Because assignment is random, you have about a 1 in 2 chance (roughly 50%) of being in the no-treatment group, assuming the groups are filled equally. Ask the coordinator to confirm the exact assignment ratio.
- How many visits does this trial involve?
- You will attend individual therapy sessions four times per week for four weeks, each session lasting 60 minutes.