---
title: A Phase 3b open-label, randomised study of IPX203 in subjects with advanced Parkinson’s disease and motor fluctuations - ADIP study
euct_id: 2025-521772-57-00
phase: Bioequivalence
status: Recruiting
sponsor: Zambon Biotech S.A.
canonical_url: "https://parkinsonspathways.com/trials/eu/2025-521772-57-00"
eu_clinical_trials_register: "https://euclinicaltrials.eu/ctis-public/view/2025-521772-57-00"
ctis_last_updated: "2026-04-21T03:50:06.967521039"
source: EU Clinical Trials Information System (CTIS)
---
# A Phase 3b open-label, randomised study of IPX203 in subjects with advanced Parkinson’s disease and motor fluctuations - ADIP study

**EU CT Number:** [2025-521772-57-00](https://euclinicaltrials.eu/ctis-public/view/2025-521772-57-00)

## Key Facts

- **Phase:** Bioequivalence
- **Status:** Recruiting
- **Sponsor:** Zambon Biotech S.A.
- **Start Date:** 2025-08-20
- **Completion Date:** 2028-07-06
- **Conditions:** Motor fluctuations in advanced Parkinson’s disease, Parkinson's disease
- **Interventions:** H006629, LEVODOPA AND DECARBOXYLASE INHIBITOR

## Member States

Trial is authorized in 3 member states: Italy, Poland, Spain.

## Sites (20)

- Niepubliczny Zaklad Opieki Zdrowotnej Neuromed M. I M. Nastaj. sp.p., Lublin, Poland
- Futuremeds Sp. z o.o., Warsaw, Poland
- Centrum Zdrowia I Urody Maxxmed, Lublin, Poland
- Neurocor Banaszkiewicz Tomaszewski Lekarze sp.p., Cracow, Poland
- Centrum Medyczne Neuroprotect, Warsaw, Poland
- Krakowska Akademia Neurologii Sp. z o.o., Cracow, Poland
- Centrum Medyczne Neuromed Sp. z o.o., Bydgoszcz, Poland
- Neurologia Śląska Centrum Medyczne, Katowice, Poland
- Etg Neuroscience Sp. z o.o., Warsaw, Poland
- Neuro-Care Sp. z o.o. sp.k., Katowice, Poland
- Hospital Universitario De La Princesa, Madrid, Spain
- Hospital Universitario 12 De Octubre, Madrid, Spain
- Hospital Universitario Ramon Y Cajal, Madrid, Spain
- Hospital De La Santa Creu I Sant Pau, Barcelona, Spain
- Hospital Universitario Puerta De Hierro De Majadahonda, Majadahonda, Spain
- Fondazione Istituto Neurologico Nazionale Casimiro Mondino, Pavia, Italy
- Azienda Ospedaliero Universitaria Delle Marche, Ancona, Italy
- Istituto Auxologico Italiano, Milan, Italy
- Azienda Ospedaliera di Padova, Padova, Italy
- Irccs San Raffaele Roma S.r.l., Rome, Italy

## Eligibility (CTIS)

- **Minimum age:** 18 Years
- **Sex:** ALL

```
Condition: Motor fluctuations in advanced Parkinson’s disease; Parkinson's disease
Age groups: elderly 65+, adults 18-64
Sex: male, female
Includes a vulnerable population.
```

---

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*Source data: https://euclinicaltrials.eu/ctis-public/view/2025-521772-57-00*