---
title: "A Study in Adults with Parkinson's Disease and a Lack of Interest or Motivation to Test How Different Doses of IRL757 Given for Multiple Days are Tolerated in the Body"
euct_id: 2025-523612-37-00
phase: Phase 3
status: Recruiting
sponsor: Integrative Research Laboratories Sweden AB
canonical_url: "https://parkinsonspathways.com/trials/eu/2025-523612-37-00"
eu_clinical_trials_register: "https://euclinicaltrials.eu/ctis-public/view/2025-523612-37-00"
ctis_last_updated: "2026-04-11T03:42:42.351993796"
source: EU Clinical Trials Information System (CTIS)
---
# A Study in Adults with Parkinson's Disease and a Lack of Interest or Motivation to Test How Different Doses of IRL757 Given for Multiple Days are Tolerated in the Body

**EU CT Number:** [2025-523612-37-00](https://euclinicaltrials.eu/ctis-public/view/2025-523612-37-00)

## Key Facts

- **Phase:** Phase 3
- **Status:** Recruiting
- **Sponsor:** Integrative Research Laboratories Sweden AB
- **Start Date:** 2025-11-17
- **Completion Date:** 2027-02-28
- **Conditions:** Parkinson's Disease and Apathy, Parkinson's disease
- **Interventions:** Placebo capsules, IRL757

## Member States

Trial is authorized in 4 member states: Bulgaria, Germany, Poland, Spain.

## Sites (17)

- Alexandrovska University Hospital, Sofia, Bulgaria
- University First multiprofile hospital for active treatment Sofia St. Joan Krastitel EAD, Sofiya, Bulgaria
- Medical Center Academica 2008 EOOD, Pleven, Bulgaria
- Medical Center Galileo OOD, Pleven, Bulgaria
- Neurologie Berlin, Clinical Practice and Study Center, Berlin, Germany
- Universitaet Muenster, Muenster, Germany
- Technische Universitaet Dresden, Dresden, Germany
- Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki W Krakowie, Cracow, Poland
- NeuroKlinika prof. ANDRZEJ BOGUCKI, Lodz, Poland
- Euromedis Sp. z o.o., Szczecin, Poland
- Centrum Medyczne Neuromed Sp. z o.o., Bydgoszcz, Poland
- Centrum Medyczne Neuroprotect, Warsaw, Poland
- Neuro-Care Sp. z o.o. sp.k., Katowice, Poland
- Hospital General Universitario De Elche, Elche, Spain
- Hospital Universitario Ramon Y Cajal, Madrid, Spain
- Hospital Victoria Eugenia De La Cruz Roja Espanola, Sevilla, Spain
- Hospital De La Santa Creu I Sant Pau, Barcelona, Spain

## Eligibility (CTIS)

- **Minimum age:** 18 Years
- **Sex:** ALL

```
Condition: Parkinson's Disease and Apathy; Parkinson's disease
Age groups: elderly 65+, adults 18-64
Sex: male, female
Includes a vulnerable population.
```

---

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