---
title: "Clinical Trials for Parkinson's Balance and Falls | Parkinson's Pathways"
description: "Recruiting Parkinson's clinical trials studying balance, postural instability, and falls. See enrolling studies and get an email when a new trial opens."
canonical_url: "https://parkinsonspathways.com/trials/symptom/balance-falls"
topic_type: symptom
source: "Parkinson's Pathways"
---
# Clinical Trials for Parkinson's Balance and Falls

Balance problems and falls are among the most consequential parts of Parkinson's, because a single fall can mean a serious injury and a loss of independence. Postural instability also tends to respond poorly to standard medications.

Trials in this area include exercise and physical therapy programs, balance training, wearable devices, and medications targeting non-dopamine pathways. Some are observational studies tracking how balance changes over time.

Below are the recruiting trials we track that focus on balance and falls. Sign up to be emailed when a new one opens.

## 98 recruiting trials

- [Feasibility and Preliminary Effectiveness of an Individualized Multimodal Group-Based Exercise Programme for People With Parkinson's Disease: A Non-Randomized Feasibility Study](https://parkinsonspathways.com/trial/NCT07618728) — Improve walking stability with exercise
- [Effects of Trunk Control Exercises and Mirror Therapy on Balance and Posture in Patients With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07610031) — Improve trunk posture and balance
- [Zesty Exercise System for Therapeutic Engagement](https://parkinsonspathways.com/trial/NCT07382674) — Improve standing reach and strength
- [Comparative Effects of Robot-Assisted Gait Training and Quadriceps Neuromuscular Electrical Stimulation Added to Standard Exercise Rehabilitation on Balance, Gait, Disease Severity, and Quadriceps Muscle Adaptations in Patients With Parkinson Disease: A Prospective Randomized Assessor-Blinded Clinical Trial](https://parkinsonspathways.com/trial/NCT07589296) — Improve walking speed and balance
- [Exoskeleton-Assisted Mobility in Aging and in Parkinson's Disease: A Mixed-Methods Study of Effectiveness and Acceptability](https://parkinsonspathways.com/trial/NCT07567482) — Exoskeleton improves balance while walking
- [Changes in Motor Function, Quality of Life, Cardiorespiratory Fitness, and Physiological Markers in People With Parkinson's Disease Following Different Exercise Interventions.](https://parkinsonspathways.com/trial/NCT07221266) — Improve walking endurance through exercise
- [Impact of Force Control of Hip Abductor Muscles on Postural Control in Middle-aged and Older Adults and Individuals With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07568951) — Improve side to side balance
- [A Pilot Study of In-lab Dynamic Standing in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07543861) — Improve walking with dynamic standing
- [COMPARATIVE EFFECTIVENESS of COLLABORATIVE VIRTUAL ENVIRONMENT and NON-IMMERSIVE VIRTUAL REALITY in the REHABILITATION of PATIENTS With PARKINSON'S DISEASE](https://parkinsonspathways.com/trial/NCT07523425) — Collaborative virtual reality improves walking
- [Stimulating the Vagus Nerve to Improve Gait in Veterans With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06562569) — Home neck stimulation improves walking
- [The Effects of Exercise Management in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07302386) — Self managed exercise improves walking
- [Adapting High-Intensity Exercise and Sleep Monitoring Technology for Home Use in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07498296) — Build strength and improve walking
- [The Effect of Motor Imagery Added to Conventional Rehabilitation on Balance and Kinesiophobia in Patients With Parkinson's Disease: A Randomized Controlled Trial](https://parkinsonspathways.com/trial/NCT07495462) — Improve balance through mental rehearsal
- [Effects of Targeted Temporal Interference Stimulation of Cerebellar Nuclei on Tremor and Gait Disturbance in Parkinson's Disease Patients](https://parkinsonspathways.com/trial/NCT07384442) — Reduce tremor and improve gait
- [Motor and Cognitive Exercise in Parkinson's Disease. A Feasibility Randomized Clinical Trial](https://parkinsonspathways.com/trial/NCT07465107) — Improve gait balance and attention
- [FREEZE-Path Cohort: Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG)](https://parkinsonspathways.com/trial/NCT07386015) — Predict falls due to freezing
- [IMPACT 360 Study for Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07443293) — Slow Parkinson progression through lifestyle
- [The Effect of Functional Rotational Exercises on Fall Risk and Mobility in Parkinson's Disease Patients: A Randomized Controlled Study](https://parkinsonspathways.com/trial/NCT07442370) — Improve mobility with rotational exercises
- [Gut-Brain Axis and Rehabilitation: Study on the Effects of C-Mill Technology on the Intestinal Microbiota of Parkinson's Disease Patients](https://parkinsonspathways.com/trial/NCT07434089) — Improve gait with C Mill
- [The Relationship Between Balance and Gait Impairments, Physical Activity Level, and Sleep Quality in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07424924) — Determine how balance affects sleep
- [A Randomized, Placebo-Controlled, Single Ascending Dose (SAD) Study to Assess the Safety, Tolerability, and Pharmacokinetics of SER-252 in Patients With Parkinson's Disease and Motor Fluctuations](https://parkinsonspathways.com/trial/NCT07422675) — Shorten daily periods without movement
- [Safety and Usability of the Cionic Neural Sleeve for Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07284823) — Improve gait with Cionic Sleeve
- [Multidimensional Evaluation of the Effectiveness of Telerehabilitation-Based Dual-Task Training in Parkinson's Patients](https://parkinsonspathways.com/trial/NCT06416722) — Improve walking while dual tasking
- [Assistive Robotic in the Elderly: Innovative Models in the Rehabilitation of the Elderly With Parkinson's Disease Through Technological Innovation](https://parkinsonspathways.com/trial/NCT04087031) — Improve walking with robotic treadmill
- [High Intensity Endurance Exercise as a Primer to Virtual Reality for Optimizing Cortical Excitability and Neuroplasticity in Parkinson's Disease (PD)](https://parkinsonspathways.com/trial/NCT06133283) — Improve balance using exercise priming
- [Study on Preliminary Safety and Efficacy of the ARC-IM Therapy to Alleviate Locomotor Deficits in People With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06295614) — Alleviate gait freezing and instability
- [The Effects of Specific Transcranial Direct Current Stimulation tDCS on Cognition in Mild Cognitive Impairment: A Novel Study Protocol](https://parkinsonspathways.com/trial/NCT05919485) — Improve thinking with brain stimulation
- [Validating a Digital Mobility Assessment in Parkinson's Disease Using Wearable Technology - the Mobilise-D Extension Study.](https://parkinsonspathways.com/trial/NCT05874739) — Validate wearable assessment of walking
- [Investigation of the Relationship Between Upper Extremity Function and Balance and Functional Mobility in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06591975) — Improve balance through arm function
- [Balance Tele-rehabilitation With Wearable Technology for Older Adults With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT05680597) — Improve balance using wearable technology
- [Medico-economic Evaluation Rehabilitation by Serious Games at Home for the Management of Patients With Parkinson's Disease Suffering From Gait and Balance Disorders](https://parkinsonspathways.com/trial/NCT04720365) — Improve gait and balance remotely
- [Motor and Cognitive Effects of Table Tennis on Parkinson's Disease: Pilot Controlled Trial](https://parkinsonspathways.com/trial/NCT06444685) — Improve walking balance and attention
- [Home Telerehabilitation Based on Serious Games for Continuity of Care in People With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT05773885) — Improve balance using telerehabilitation games
- [Clinical Validity of the DANU Sports System for Gait and Balance Assessment in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07281794) — Detect walking and balance problems
- [Steps Against the Burden of Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07058285) — Reduce falls with treadmill training
- ["Amazonian Dance for Parkinson": a Protocol Study for a Randomized Clinical Trial on Motor and Non-motor Symptoms of People With Parkinson's.](https://parkinsonspathways.com/trial/NCT06967493) — Improve walking through Amazonian dance
- [Effects of Transcranial Direct Current Stimulation Over the Supplementary Motor Area Combined With Nordic Walking on Gait and Balance in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07381907) — Improve walking speed and balance
- [Adaptive/Closed Loop vs. Continuous/Open Loop Deep Brain Stimulation of Subthalamic Nucleus: a Two-Phase, Cross-Over, Double-Blind Trial in Patients With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT05402163) — Improve gait balance and speech
- [Which Tools Better Predict Fall Risk in Parkinson's Disease: A Comparative Study of Objective, Self-Reported, and Functional Balance Assessment](https://parkinsonspathways.com/trial/NCT07148700) — Predict falls by assessing balance
- [Rhythmic Auditory Stimulaton Using Personalized Music Therapy in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07378722) — Improve walking speed and balance
- [Deep Brain Stimulation for Visuomotor Function in Parkinsons Disease](https://parkinsonspathways.com/trial/NCT05400499) — Improve vision guided reaching ability
- [Effects of Motor Imagery Training on Kinesiophobia, Gait, and Balance in Parkinson's Disease Patients](https://parkinsonspathways.com/trial/NCT07193355) — Improve walking confidence through imagery
- [Parkinson's Disease Rehabilitation Using Neurofeedback With Functional Electrical Stimulation and Virtual Reality Feedback for Lower Extremities](https://parkinsonspathways.com/trial/NCT06690931) — Improve walking and leg function
- [Effects of Visual Indicator Exercises for the Trunk and Lower Extremities on Activity and Participation in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07322939) — Improve walking using visual feedback
- [Objective Mobility Assessment Using Wearable Technology for Clinical Application in Parkinson's Disease: From Validation to Fall Prediction](https://parkinsonspathways.com/trial/NCT07281755) — Predict falls using wearable technology
- [Study of the Progression of Axial and Cognitive Symptoms and Biomarkers of Neurodegeneration in Patients With Parkinson's Disease Divided Into Brain-first and Body-first Phenotypes](https://parkinsonspathways.com/trial/NCT07187843) — Track axial and cognitive progression
- [Aim 3 Particle Swarm Optimization Postural Instability Gait Disorder](https://parkinsonspathways.com/trial/NCT05934747) — Optimize brain stimulation improving walking
- [Vestibular and Cortical Contributions to Transitions in Freezing of Gait in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06506058) — Reduce freezing episodes while walking
- [The Novel Application of fNIRS-based Neurofeedback to Enhance Effects of Motor Imagery on Balance and Gait Performance in Individuals With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT05800470) — Improve walking balance with neurofeedback
- [Utilization of Robotic EksoSkeleton to Achieve High Dosing, Intensity, and Complexity of Gait in Treatment of People With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06225830) — Improve walking via robotic exoskeleton
- [Comparison of Two Home-based Gait and Balance Trainings With Different Training Frequencies in Patients With Parkinson's Disease and Ataxia](https://parkinsonspathways.com/trial/NCT06617884) — Enhance home walking and balance
- [The Effect of Exercise Intervention on Posture, Trunk Flexibility and Spine Function in Patients With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06536478) — Improve posture and trunk flexibility
- [Investigating Neural Biomarkers for Gait in Parkinson's Patients](https://parkinsonspathways.com/trial/NCT05820074) — Improve gait using Percept neurostimulation
- [StepuP: Steps Against the Burden of Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07057219) — Improve walking speed through exercise
- [Effects of an External and Combined Focus of Attention-Instructed Exercise Program on Postural Stability and Dual-Task Walking in Parkinson's Disease: A Randomized, Assessor-Blinded, Controlled Trial](https://parkinsonspathways.com/trial/NCT06615115) — Improve balance during dual tasking
- [Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06088355) — Increase walking endurance through exercise
- [Development of Digital Diagnostic Devices for Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06663826) — Detect freezing through oculomotor markers
- [Feasibility and Preliminary Effects of the Walking Tall App for Home-Based Gait Training in Parkinson's Disease: A Pilot Study](https://parkinsonspathways.com/trial/NCT07380737) — Improve gait through smartphone training
- [A Double-blinded, Randomized, Parallel-group, Superiority Study to Explore the Neuroprotective Effects of Long-term Transcutaneous Auricular Vagus Nerve Stimulation(taVNS) in Early Parkinson's Disease(PD) Patients](https://parkinsonspathways.com/trial/NCT06665113) — Ear stimulation slows Parkinson progression
- [Rehabilitation of Locomotor Function in Parkinson's Disease by Non-invasive Spinal Cord Stimulation](https://parkinsonspathways.com/trial/NCT06804642) — Improve walking with spinal stimulation
- [Exercise for Cognitive Excellence in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT05720468) — Improve cognition through supervised exercise
- [SegwayPD: The Effect of Sensory-augmented Postural Training Using Segway on Motor and Cognitive Function in Individuals With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT05982730) — Improve balance using Segway training
- [Kinematic and Neural Dynamics of Postural Instability in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06405334) — Predict falls by mapping movements
- [Preventing Freezing of Gait in Parkinson's Disease Using Soft Robotic Apparel](https://parkinsonspathways.com/trial/NCT06602544) — Reduce freezing episodes during walking
- [Step Up to PD: A Community-based Walking Program for People With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06859528) — Increase walking distance and endurance
- [Effectiveness of a High-intensity Functional Training (HIFT) Program on Functional and Cognitive Performance in People with Parkinson's Disease.](https://parkinsonspathways.com/trial/NCT06879821) — Improve everyday movement and thinking
- [Blood Flow Restriction for Optimizing Balance in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06508801) — Reduce falls by improving balance
- [Affordances and Impairments: A Paradigm for Understanding Obstacle Crossing in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06932679) — Improve obstacle crossing while walking
- [Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-Netherlands](https://parkinsonspathways.com/trial/NCT06193252) — Slow Parkinson progression through exercise
- [Balance Confidence, Kinesiophobia, and Associated Factors in Parkinson's Disease: A Controlled Study](https://parkinsonspathways.com/trial/NCT06751797) — Identify factors behind balance confidence
- [A Multimodal Exercise Program With Gamification (MEP+G) in Individuals With Parkinson Disease: a Pilot Randomized Controlled Trial](https://parkinsonspathways.com/trial/NCT06538298) — Improve balance using gamified exercise
- [Using the NUSHU Shoe to Analyze Gait Balance and Vibrotactile Feedback in Early, Moderate and Advanced PD Patients and Healthy Controls](https://parkinsonspathways.com/trial/NCT06975059) — Vibrating shoe improves walking stability
- [Effect of Combined PAS Balance Training on Individuals With PD](https://parkinsonspathways.com/trial/NCT06598891) — Reduce falls by improving balance
- [STEPWISE Parkinson: A Smartphone Based, Titrated Exercise Solution for Patients With Parkinson's Disease in Daily Life](https://parkinsonspathways.com/trial/NCT04848077) — Increase daily walking step count
- [Efficacy of Integrating Artificial Intelligence Solutions in Rehabilitation in Postural Trunk Disorders in Parkinson's Disease.](https://parkinsonspathways.com/trial/NCT07010328) — Reduce forward and sideways leaning
- [exPDite-2: A Phase 3 Study to Assess the Efficacy and Safety of Midbrain Dopaminergic Neuronal Cell Therapy (Bemdaneprocel) for Participants With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06944522) — Reduce daily off medication time
- [Using Biofeedback During Exergaming to Attenuate Alpha Oscillations to Improve Postural Control in People Living With Parkinson's.](https://parkinsonspathways.com/trial/NCT05986643) — Improve balance using neurofeedback exergaming
- [A Pilot RCT of a Remote Physical Activity Coaching Intervention to Promote Engagement in Physical Activity for People With Parkinson's Disease in Qatar](https://parkinsonspathways.com/trial/NCT06962930) — Boost Parkinson patients physical activity
- [The Benefits of Hippotherapy for Patients With Parkinson's Disease of 75 Years of Age or More at Risk of Losing Their Independance.](https://parkinsonspathways.com/trial/NCT06500182) — Hippotherapy improves balance and mobility
- [Steps Against the Burden of Parkinson's Disease - TelAviv/Bologna](https://parkinsonspathways.com/trial/NCT07105787) — Improve walking speed and stability
- [Management of Initial Parkinson's Disease: a Prospective, Mono-centric, no Profit Pilot Clinical Trial Comparing Conventional Face-to-face Physiotherapy and Home-based Telerehabilitation](https://parkinsonspathways.com/trial/NCT06052280) — Improve gait and balance remotely
- [Effect of Action Observation and Motor Imagery Therapy on Balance, Functional Status and Quality of Life in Parkinson's Disease, Randomized Controlled Trial](https://parkinsonspathways.com/trial/NCT06154356) — Improve balance with motor imagery
- [The Use of the CUE1/CUE1+ Device in People With Idiopathic Parkinson's Disease and Related Disorders: A Feasibility Study](https://parkinsonspathways.com/trial/NCT06174948) — Improve walking rhythm and balance
- [Effects of Targeted Amino Acid Supplementation for People With Parkinson's Disease on Amino Acid Profiles and Health Related Markers](https://parkinsonspathways.com/trial/NCT07115563) — Rebalance neurotransmitter precursors with supplement
- [Pathways Mediating Impaired Postural Control in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06464029) — Pinpoint causes of balance problems
- [Evaluation of the Effects of Aquatic Therapy on Activities of Daily Living, Walking, Balance, Posture, Pain, and Depression in Parkinson's Patients](https://parkinsonspathways.com/trial/NCT07390825) — Improve walking balance via aquatherapy
- [Virtual Reality Verses Conventional Physical Therapy in Parkinson's Disease Patients](https://parkinsonspathways.com/trial/NCT07359716) — Improve balance through virtual reality
- [Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male](https://parkinsonspathways.com/trial/NCT07084597) — Stabilize heart and blood pressure
- [Mechanism and Application of Deep Brain Stimulation in the Treatment of Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06400017) — Reduce tremor and improve movement
- [Neurotech PD Gait: Multisite Non-invasive Electrical Stimulation to Optimize Motor-cognitive Rehabilitation Response in Parkinson's Disease Subjects With Postural Instability and Gait Disorders](https://parkinsonspathways.com/trial/NCT06868160) — Improve walking balance and thinking
- [Role of the Subthalamic Nucleus in the Control of Movement: Physiopathology of Akinesia in Parkinson's Disease.](https://parkinsonspathways.com/trial/NCT01682668) — Brain stimulation reduces movement fluctuations
- [Comparison of Changes in Neuromuscular and Functional Performance Due to Resistance Training With Low-Load or High-Load in Persons With Parkinson's Disease.](https://parkinsonspathways.com/trial/NCT07378813) — Improve walking using resistance training
- [The Effectiveness of Mixed Reality as Interventional Tool for the Improvement on Quality of Life for People With Parkinson´s Disease. Randomized Control Trial](https://parkinsonspathways.com/trial/NCT06459154) — Improve walking with mixed reality
- [Evaluation of the Effectiveness of the Parkinson's Specialized Teams Intervention on the Quality of Life of Parkinson's Patients in the Territory of the Nouvelle-Aquitaine and Hauts-de-France: ES-Park Pilot Study.](https://parkinsonspathways.com/trial/NCT05433441) — Improve daily functioning through teams
- [The Clinical Application of Clostridium Butyricum Miyairisan for Motor and Non-motor Symptoms in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06548256) — Reduce motor and nonmotor symptoms
- [Feasibility and Safety of a Portable Exoskeleton to Improve Mobility in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06028529) — Improve walking mobility using exoskeleton
- [Study on Preliminary Safety and Efficacy of Adaptive DBS Aligned to Locomotor States to Improve Locomotor Functions in Parkinson's Patients](https://parkinsonspathways.com/trial/NCT06791902) — Reduce freezing and improve walking
- [Safety and Efficacy of Personalized Repetitive Transcranial Magnetic Stimulation Protocol Based on Functional Reserve to Enhance Ambulatory Function in Patients With Parkinson Disease](https://parkinsonspathways.com/trial/NCT06350617) — Personalized stimulation to improve walking

## Related topics

- [Freezing of Gait](https://parkinsonspathways.com/trials/symptom/freezing-of-gait)
- [Tremor](https://parkinsonspathways.com/trials/symptom/tremor)

## Related

- [Browse all recruiting trials](https://parkinsonspathways.com/trials)
- [Match yourself to relevant trials](https://parkinsonspathways.com/match)
- [Get the free Monday digest of new recruiting Parkinson's trials](https://parkinsonspathways.com/digest)