---
title: "Clinical Trials for Parkinson's Pain | Parkinson's Pathways"
description: "Recruiting Parkinson's clinical trials studying pain. See enrolling studies testing new treatments for the pain that often comes with Parkinson's, and get notified of new trials."
canonical_url: "https://parkinsonspathways.com/trials/symptom/pain"
topic_type: symptom
source: "Parkinson's Pathways"
---
# Clinical Trials for Parkinson's Pain

Pain is a surprisingly common part of Parkinson's that often goes unrecognized. It can come from muscle stiffness and cramping, dystonia, changes in posture, or the way the disease affects how the brain processes pain itself.

Trials in this area test medications, exercise and physical therapy approaches, and devices aimed at reducing pain, as well as studies that measure how pain changes with Parkinson's treatment over time.

Below are the recruiting trials we track that focus on pain. Sign up to be emailed when a new one opens.

## 18 recruiting trials

- [Impact of Force Control of Hip Abductor Muscles on Postural Control in Middle-aged and Older Adults and Individuals With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07568951), Improve side to side balance
- [A Pilot Study of In-lab Dynamic Standing in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07543861), Improve walking with dynamic standing
- [Evaluation of the Safety of Electrical Spinal Cord Stimulation in Parkinson's Patients Presenting With Painful Camptocormia](https://parkinsonspathways.com/trial/NCT06291051), Reduce camptocormia pain with stimulation
- [Revision of Deep Brain Stimulator in Patients With Parkinson's Disease: A Comparison of Perioperative Characteristics of Regional and General Anesthesia](https://parkinsonspathways.com/trial/NCT07176494), Numbing surgical area speeds recovery
- [Esketamine in Microelectrode Recording-guided Subthalamic Deep-Brain Stimulation for Parkinson's Disease（ASPIRE）：A Randomized Controlled, Double-blind Study](https://parkinsonspathways.com/trial/NCT06543563), Preserve brain signals during surgery
- [The Effects of Specific Transcranial Direct Current Stimulation tDCS on Cognition in Mild Cognitive Impairment: A Novel Study Protocol](https://parkinsonspathways.com/trial/NCT05919485), Improve thinking with brain stimulation
- [Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms: Identification of Predictive Patterns of Rehabilitation Outcome and Evaluation of the Impact on Quality of Life](https://parkinsonspathways.com/trial/NCT05748028), Reduce pain and autonomic symptoms
- [Observational Case Series of Patients With Parkinson's Disease (PD) Attending a Complementary Medicine Neuro-degenerative Disease (NDD) Clinic.](https://parkinsonspathways.com/trial/NCT07207096), Complementary medicine to reduce stiffness
- [The Effect of Exercise Intervention on Posture, Trunk Flexibility and Spine Function in Patients With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06536478), Improve posture and trunk flexibility
- [Effects Of Osteopathic Manipulative Medicine(OMM) On Lower Extremity Muscle Characteristics In Parkinson's Disease(PD) Patients](https://parkinsonspathways.com/trial/NCT05884944), Reduce lower extremity muscle stiffness
- [Comparing Pain Intensity and Discomfort in Patients With Parkinson´s Disease and Healthy Controls During Inducement of Mechanical, Thermal, and Chemical Experimental Pain](https://parkinsonspathways.com/trial/NCT05981261), Assess experimental pain in Parkinsons
- [Pathophysiology of Pain in Parkinson's Disease: Exploration of the Serotonin System in Positron Emission Tomography (PET [18F]-MPPF)](https://parkinsonspathways.com/trial/NCT06008704), Identify serotonin abnormalities causing pain
- [A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis: a Single-center, Randomized, Double-blind Study](https://parkinsonspathways.com/trial/NCT06304285), Can gut acupuncture ease movement
- [Determination of the Minimal Detectable Change and Minimum Clinically Important Change Score of the Parkinson's Disease Questionnaire-8](https://parkinsonspathways.com/trial/NCT06487364), Rehabilitation measures meaningful daily improvements
- [Acupuncture for the Treatment of Parkinson's Disease Related Constipation](https://parkinsonspathways.com/trial/NCT06390761), Relieve Parkinson constipation through acupuncture
- [Observational Study Evaluating Subcutaneous LDp/CDp Solution for Infusion Effectiveness on Sleep Disturbances in Advanced Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07284342), Improve sleep with skin infusion
- [Evaluation of the Effects of Aquatic Therapy on Activities of Daily Living, Walking, Balance, Posture, Pain, and Depression in Parkinson's Patients](https://parkinsonspathways.com/trial/NCT07390825), Improve walking balance via aquatherapy
- [Stimulation of the External Pallidal Segment for Insomnia in Patients With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT04116996), Improve insomnia with pallidal stimulation

## Related topics

- [OFF Time](https://parkinsonspathways.com/trials/symptom/off-time)
- [Balance & Falls](https://parkinsonspathways.com/trials/symptom/balance-falls)

## Related

- [Browse all recruiting trials](https://parkinsonspathways.com/trials)
- [Match yourself to relevant trials](https://parkinsonspathways.com/match)
- [Get the free Monday digest of new recruiting Parkinson's trials](https://parkinsonspathways.com/digest)