---
title: "Clinical Trials for Parkinson's Psychosis | Parkinson's Pathways"
description: "Recruiting Parkinson's clinical trials studying psychosis, hallucinations, and delusions. See enrolling studies and get notified of new trials."
canonical_url: "https://parkinsonspathways.com/trials/symptom/psychosis"
topic_type: symptom
source: "Parkinson's Pathways"
---
# Clinical Trials for Parkinson's Psychosis and Hallucinations

Some people with Parkinson's experience hallucinations or delusions, sometimes as a feature of the disease and sometimes as a side effect of medication. Parkinson's disease psychosis can be distressing for both patients and caregivers, and it is an active area of research.

Trials in this space test medications designed to reduce hallucinations without worsening movement symptoms, as well as studies that look at the causes and course of psychosis over time.

Below are the recruiting trials we track that focus on psychosis and hallucinations. Sign up to be emailed when a new one opens.

## 14 recruiting trials

- [Brain Glutathione (GSH) Enrichment Through Gamma-glutamylcysteine (GGC) Supplementation in Early Parkinson's Disease Patients for Reduction of Extrapyramidal Motor Disturbances and Halting Cognition Decline: A Pilot Trial](https://parkinsonspathways.com/trial/NCT07064005) — Reduce movement problems with supplement
- [Ultra-High Resolution PET of the Human Brain and Spinal Cord in Healthy Aging, Dementia, Movement Disorders, ALS and Psychotic Disorders](https://parkinsonspathways.com/trial/NCT07509125) — Distinguish Parkinson from related disorders
- [Dose-Escalation, Single-Center, Open-label Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of Adeno-associated Virus(AAV) Gene Therapy Product IPS101A in Parkinson's Disease Patients With Hoehn-Yahr Stage 4-5, Diagnosed in More Than 10 Years and Uncontrolled by All Available Monotherapy or Combination Therapy](https://parkinsonspathways.com/trial/NCT07371338) — Reduce medication resistant motor symptoms
- [Multi-Stakeholder Engagement for Interdisciplinary Telehealth in Lewy Body Dementia](https://parkinsonspathways.com/trial/NCT05014971) — Improve access to specialist care
- [Clinical Trial Evaluating the Efficacy and Safety of AGB101 for Treatment of Parkinson's Disease Related Psychosis](https://parkinsonspathways.com/trial/NCT05824728) — Reduce hallucinations without worsening movement
- [Clinical Study Evaluating the Efficacy and Safety of Synbiotic as an Adjuvant Therapy in the Treatment of Parkinson's Disease](https://parkinsonspathways.com/trial/NCT05576818) — Reduce motor symptoms using synbiotic
- [Genetics in Parkinson's Disease: Behavioral and Cognitive Outcomes in Patients Undergoing Dopaminergic Treatment](https://parkinsonspathways.com/trial/NCT06329739) — Genes affect medication side effects
- [A Pragmatic Randomized Trial Comparing Antipsychotics in Lewy Body Disease](https://parkinsonspathways.com/trial/NCT05590637) — Compare pimavanserin and quetiapine effectiveness
- [Transcranial Direct Current Stimulation (tDCS) to Improve Motor Function and Motor Fatigue in Parkinson's Patients](https://parkinsonspathways.com/trial/NCT06883266) — Reduce movement slowness and fatigue
- [CSP #2015 - Multicenter, Randomized, Double-blind Comparator Study of Antipsychotics Pimavanserin and Quetiapine for Parkinson''s Disease Psychosis (C-SAPP)](https://parkinsonspathways.com/trial/NCT04373317) — Reduce hallucinations without worsening movement
- [Efficacy of Deep Brain Stimulation and Levodopa on Freezing of Gait in Advanced Parkinson's Disease: a Comparative Study](https://parkinsonspathways.com/trial/NCT06316232) — Reduce freezing episodes during walking
- [Subthalamic and Cortical Electrophysiological Correlates of Motor and Neuropsychiatric Fluctuations in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07404241) — Reduce motor and neuropsychiatric fluctuations
- [Safety, Tolerability and Exploratory Efficacy of EC5026 in Parkinson's Disease (STEP Study)](https://parkinsonspathways.com/trial/NCT07142044) — Slow Parkinson brain cell loss
- [Enhancing Psychological Wellbeing and the Patient-caregiver Relationship Through Dyadic Mindfulness: A Randomized Controlled Trial in People With Parkinson's Disease and Their Caregivers](https://parkinsonspathways.com/trial/NCT06821230) — Reduce depression anxiety and stress

## Related topics

- [Cognition & Memory](https://parkinsonspathways.com/trials/symptom/cognition)

## Related

- [Browse all recruiting trials](https://parkinsonspathways.com/trials)
- [Match yourself to relevant trials](https://parkinsonspathways.com/match)
- [Get the free Monday digest of new recruiting Parkinson's trials](https://parkinsonspathways.com/digest)