---
title: "Clinical Trials for Parkinson's Speech and Swallowing | Parkinson's Pathways"
description: "Recruiting Parkinson's clinical trials studying speech, voice, and swallowing difficulties. See enrolling studies and get an email when a new trial opens."
canonical_url: "https://parkinsonspathways.com/trials/symptom/speech-swallowing"
topic_type: symptom
source: "Parkinson's Pathways"
---
# Clinical Trials for Parkinson's Speech and Swallowing

Changes to speech, voice, and swallowing are common in Parkinson's and can have a big effect on daily life and safety. A quieter voice, slurred speech, and trouble swallowing can make communication and eating harder, and swallowing problems carry real health risks.

Trials in this area test speech and voice therapy programs, devices, and exercises designed to strengthen swallowing, along with studies that track how these functions change over time.

Below are the recruiting trials we track that focus on speech and swallowing. Sign up to be emailed when a new one opens.

## 29 recruiting trials

- [A Single-Center, Double-Blind Randomized Controlled Trial of Different Frequency Temporal Interference Stimulation Applied to Bilateral Subthalamic Nucleus for Improving Motor and Vocal Functions in Patients With Parkinson's Disease.](https://parkinsonspathways.com/trial/NCT07721688), Testing stimulation for movement speech
- [A Pilot Study of Acute Intermittent Hypercapnia-Based Interventions on Upper Airway and Axial Motor Function in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07674264), Improve speech cough and breathing
- [Nutritional Intervention for Constipation Symptoms in Patients With Parkinson's Disease: A Randomized Clinical Trial](https://parkinsonspathways.com/trial/NCT07213856), Reduce constipation using dietitian guidance
- [Biomechanical Effects of Expiratory Muscle Strength Training (EMST®) on Swallowing Function in Parkinson's Disease - a Prospective High-resolution Manometry Study](https://parkinsonspathways.com/trial/NCT07606547), Improve swallowing through breath training
- [Speech Amplification Devices for Parkinson and Related Diseases: Talker- and Technology-Driven Enhancements](https://parkinsonspathways.com/trial/NCT07599696), Improve speech volume with amplification
- [Effects of Transcutaneous Stimulation of the Auricular Branch of the Vagus Nerve in Parkinson´s Disease](https://parkinsonspathways.com/trial/NCT07588191), Improve voice and swallowing function
- [A Single-Center, Double-Blind Randomized Controlled Trial of Accelerated Temporal Interference Stimulation Applied to Bilateral Subthalamic Nucleus for Improving Motor and Vocal Functions in Patients With Parkinson's Disease Or Secondary Parkinson's Syndrome](https://parkinsonspathways.com/trial/NCT07568067), Improve speech with brain stimulation
- [FREEZE-Path Cohort: Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG)](https://parkinsonspathways.com/trial/NCT07386015), Track freezing of gait progression
- [Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients](https://parkinsonspathways.com/trial/NCT07455760), Improve speech sequencing with stimulation
- [REducing SPEECH-related Side-effects of Deep Brain Stimulation in Parkinson's Disease Via Automated Speech Analysis](https://parkinsonspathways.com/trial/NCT05182892), Reduce stimulation induced speech problems
- [Adaptive/Closed Loop vs. Continuous/Open Loop Deep Brain Stimulation of Subthalamic Nucleus: a Two-Phase, Cross-Over, Double-Blind Trial in Patients With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT05402163), Test adaptive stimulation for walking
- [Deep Brain Stimulation in Parkinson's Disease: Respiratory Testing](https://parkinsonspathways.com/trial/NCT04058457), Brain stimulation changes breathing function
- [Understand Me for Life: Using Noise-augmented Automatic Speech Recognition to Improve Intelligibility in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06540989), Improve speech clarity with feedback
- [Clinical Efficacy and Mechanism of tDCS for Dysphagia in Patients With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07153692), Improve swallowing safety and function
- [Sensory Filtering in the Human Basal Ganglia as a Mechanism of Parkinson's Disease](https://parkinsonspathways.com/trial/NCT05482126), Improve movement by filtering sensations
- [Rehabilitation of Airway Protection in Parkinson's Disease: Comparing In-person and Telehealth Service Delivery Models](https://parkinsonspathways.com/trial/NCT05700825), Strengthen cough to reduce aspiration
- [The Effect of an Auditory Rhythmic Cue on the Frequency of Rolling in Patients with Dysphagia and Parkinson's Disease: a Pilot Study](https://parkinsonspathways.com/trial/NCT06695455), Reduce tongue rolling during swallowing
- [Study on Artificial Intelligence-Based Facial and Speech-Related Patterns in Parkinson's Disease and Their Digital Biomarkers](https://parkinsonspathways.com/trial/NCT07392411), Distinguish Parkinson from similar disorders
- [Study of the Link Between Freezing of Gait and Oropharyngeal Freezing in Parkinson's Patients](https://parkinsonspathways.com/trial/NCT06713265), Link gait freezing with swallowing
- [A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis: a Single-center, Randomized, Double-blind Study](https://parkinsonspathways.com/trial/NCT06304285), Can gut acupuncture ease movement
- [Contribution of the Kinematic Theory in the Early Differential Diagnosis of the Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06161636), Use kinematics to diagnose Parkinson
- [Relationship Between Speech Perceptual Learning and Speech Production in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07403539), Improve speech clarity through listening
- [A Digital Therapeutic Platform for Swallowing and Drooling Problems in Parkinson's](https://parkinsonspathways.com/trial/NCT04664634), Reduce drooling and improve swallowing
- [Biological Determinants and Neural Compensatory Mechanisms of Oropharyngeal Dysphagia in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT07299448), Identify neural causes of dysphagia
- [SPEECH as Biomarker for Emotion, Movement and cOgnition in Parkinson's Disease](https://parkinsonspathways.com/trial/NCT05765110), Speech tracks movement mood thinking
- [Effect of Forward Trunk Flexion in Patients With Parkinson's Disease on the Airway Defense System](https://parkinsonspathways.com/trial/NCT06955377), Strengthen cough by forward flexion
- [Listener Training for Improved Intelligibility of People With Parkinson's Disease](https://parkinsonspathways.com/trial/NCT06815263), Improve intelligibility of Parkinson speech
- [Neurophysiological, Behavioral, and Cognitive Networks in Movement Disorders](https://parkinsonspathways.com/trial/NCT04061135), Can brain recordings explain movement
- [Prospective Observational Study for the Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases](https://parkinsonspathways.com/trial/NCT04706234), Map swallowing and voice function

## Related topics

- [Balance & Falls](https://parkinsonspathways.com/trials/symptom/balance-falls)
- [Cognition & Memory](https://parkinsonspathways.com/trials/symptom/cognition)

## Related

- [Browse all recruiting trials](https://parkinsonspathways.com/trials)
- [Match yourself to relevant trials](https://parkinsonspathways.com/match)
- [Get the free Monday digest of new recruiting Parkinson's trials](https://parkinsonspathways.com/digest)