Reduce tremor through neurosurgical evaluation
- Trial ID
- NCT00060541
- Official Title
- Evaluation and Treatment of Neurosurgical Disorders
- Goal
- Reduce tremor through neurosurgical evaluation
- Status
- RECRUITING
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
- Study Type
- OBSERVATIONAL
- Enrollment
- 5000 participants
- Conditions
- Neurologic Disorders
- Interventions
- Laboratory tests, Radiological exams
Plain-Language Summary
The goal is to evaluate and manage people with a wide range of neurosurgical problems, including Parkinson's disease, so clinicians can improve diagnosis, guide treatment decisions, and build a research resource of clinical data and biological samples. Participants get detailed clinical exams, lab tests, imaging like MRI, and optional skin, saliva, or blood samples and genetic testing to characterize the problem and decide on treatments such as tumor surgery or deep brain stimulation. Deep brain stimulation involves implanting electrodes to modulate overactive brain circuits, which can reduce motor symptoms and often allow lower levodopa doses. People aged 4 and older who are referred to the Surgical Neurology Branch for evaluation and can consent, or have a guardian to consent, are eligible; those unable to undergo evaluation are excluded, and close relatives may enroll for genetic testing only.
Locations
- National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Laboratory tests. The goal is to evaluate and manage people with a wide range of neurosurgical problems, including Parkinson's disease, so clinicians can improve diagnosis, guide treatment decisions, and build a research resource of clinical data and biological samples. Participants get detailed clinical exams, lab tests, imaging like MRI, and optional skin, saliva, or blood samples and genetic testing to characterize the problem and decide on treatments such as tumor surgery or deep brain stimulation. Deep brain stimulation involves implanting electrodes to modulate overactive brain circuits, which can reduce motor symptoms and often allow lower levodopa doses. People aged 4 and older who are referred to the Surgical Neurology Branch for evaluation and can consent, or have a guardian to consent, are eligible; those unable to undergo evaluation are excluded, and close relatives may enroll for genetic testing only.
- Who can participate?
- Participants must be between 4 Years and 99 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- The estimated duration for this trial is not yet available. Trials typically last several months to a few years depending on the study design.