Laboratory tests for Parkinson's (NCT00060541)
Reduce tremor through neurosurgical evaluation
- Trial ID
- NCT00060541
- Official Title
- Evaluation and Treatment of Neurosurgical Disorders
- Goal
- Reduce tremor through neurosurgical evaluation
- Status
- RECRUITING
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
- Study Type
- OBSERVATIONAL
- Enrollment
- 5000 participants
- Conditions
- Neurologic Disorders
- Interventions
- Laboratory tests, Radiological exams
Summary For Families
The goal is to evaluate and manage people with a wide range of neurosurgical problems, including Parkinson's disease, so clinicians can improve diagnosis, guide treatment decisions, and build a research resource of clinical data and biological samples. Participants get detailed clinical exams, lab tests, imaging like MRI, and optional skin, saliva, or blood samples and genetic testing to characterize the problem and decide on treatments such as tumor surgery or deep brain stimulation. Deep brain stimulation involves implanting electrodes to modulate overactive brain circuits, which can reduce motor symptoms and often allow lower levodopa doses. People aged 4 and older who are referred to the Surgical Neurology Branch for evaluation and can consent, or have a guardian to consent, are eligible; those unable to undergo evaluation are excluded, and close relatives may enroll for genetic testing only.
Locations
- National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Laboratory tests. The goal is to evaluate and manage people with a wide range of neurosurgical problems, including Parkinson's disease, so clinicians can improve diagnosis, guide treatment decisions, and build a research resource of clinical data and biological samples. Participants get detailed clinical exams, lab tests, imaging like MRI, and optional skin, saliva, or blood samples and genetic testing to characterize the problem and decide on treatments such as tumor surgery or deep brain stimulation. Deep brain stimulation involves implanting electrodes to modulate overactive brain circuits, which can reduce motor symptoms and often allow lower levodopa doses. People aged 4 and older who are referred to the Surgical Neurology Branch for evaluation and can consent, or have a guardian to consent, are eligible; those unable to undergo evaluation are excluded, and close relatives may enroll for genetic testing only.
- Who can participate?
- Participants must be between 4 Years and 99 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- The estimated duration for this trial is not yet available. Trials typically last several months to a few years depending on the study design.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Biopsy (invasive). Confirm the full schedule with the study coordinator.