Parkinson's Trial NCT00874783
Create personalized stem cell therapies
- Trial ID
- NCT00874783
- Official Title
- Derivation of Induced Pluripotent Stem Cells from Somatic Cells Donated by Patients with Neurological Diseases for the Study of the Pathogenesis of the Disorders and Development of Novel Therapies
- Goal
- Create personalized stem cell therapies
- Status
- RECRUITING
- Sponsor
- Hadassah Medical Organization
- Study Type
- OBSERVATIONAL
- Enrollment
- 120 participants
- Conditions
- Neurodegenerative Disorders
Summary For Families
The goal is to make patient-derived stem cell models so researchers can see how neurodegenerative diseases start and help develop new therapies. Donors give a small sample of tissue or a few intact hairs, those somatic cells are reprogrammed into induced pluripotent stem cells and then turned into neurons in the lab so scientists can study disease processes and test potential drugs on cells with the patient’s own genetics. The study is looking for adults 18 and older who have a diagnosed neurodegenerative disorder and can donate tissue during a medical procedure or a few hairs, and it also accepts healthy adult donors, aiming for about 120 participants. There is no experimental treatment given to participants, and no exclusion criteria were listed.
Locations
- Hadassah Ein Kerem, Jerusalem, Israel, Israel
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. The goal is to make patient-derived stem cell models so researchers can see how neurodegenerative diseases start and help develop new therapies. Donors give a small sample of tissue or a few intact hairs, those somatic cells are reprogrammed into induced pluripotent stem cells and then turned into neurons in the lab so scientists can study disease processes and test potential drugs on cells with the patient’s own genetics. The study is looking for adults 18 and older who have a diagnosed neurodegenerative disorder and can donate tissue during a medical procedure or a few hairs, and it also accepts healthy adult donors, aiming for about 120 participants. There is no experimental treatment given to participants, and no exclusion criteria were listed.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 21 years and 8 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Biopsy (invasive). Confirm the full schedule with the study coordinator.