Create personalized stem cell therapies
- Trial ID
- NCT00874783
- Official Title
- Derivation of Induced Pluripotent Stem Cells from Somatic Cells Donated by Patients with Neurological Diseases for the Study of the Pathogenesis of the Disorders and Development of Novel Therapies
- Goal
- Create personalized stem cell therapies
- Status
- RECRUITING
- Sponsor
- Hadassah Medical Organization
- Study Type
- OBSERVATIONAL
- Enrollment
- 120 participants
- Conditions
- Neurodegenerative Disorders
Plain-Language Summary
The goal is to make patient-derived stem cell models so researchers can see how neurodegenerative diseases start and help develop new therapies. Donors give a small sample of tissue or a few intact hairs, those somatic cells are reprogrammed into induced pluripotent stem cells and then turned into neurons in the lab so scientists can study disease processes and test potential drugs on cells with the patient’s own genetics. The study is looking for adults 18 and older who have a diagnosed neurodegenerative disorder and can donate tissue during a medical procedure or a few hairs, and it also accepts healthy adult donors, aiming for about 120 participants. There is no experimental treatment given to participants, and no exclusion criteria were listed.
Locations
- Hadassah Ein Kerem, Jerusalem, Israel, Israel
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. The goal is to make patient-derived stem cell models so researchers can see how neurodegenerative diseases start and help develop new therapies. Donors give a small sample of tissue or a few intact hairs, those somatic cells are reprogrammed into induced pluripotent stem cells and then turned into neurons in the lab so scientists can study disease processes and test potential drugs on cells with the patient’s own genetics. The study is looking for adults 18 and older who have a diagnosed neurodegenerative disorder and can donate tissue during a medical procedure or a few hairs, and it also accepts healthy adult donors, aiming for about 120 participants. There is no experimental treatment given to participants, and no exclusion criteria were listed.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 21 years and 8 months.