PaGeR (NCT01558479)
Identify inherited genes causing Parkinson
- Trial ID
- NCT01558479
- Official Title
- The Parkinson's Genetic Research Study (PaGeR)
- Study Acronym
- PaGeR
- Goal
- Identify inherited genes causing Parkinson
- Status
- RECRUITING
- Sponsor
- University of Washington
- Study Type
- OBSERVATIONAL
- Enrollment
- 5000 participants
- Conditions
- Parkinson's Disease
Summary For Families
PaGeR looks for inherited genetic changes that increase the risk of Parkinson's or shape how the disease starts and progresses in families, with the goal of pointing to biological pathways for future tests or treatments. Researchers gather family histories and DNA samples from relatives in affected families and analyze genetic variants across those families, this is observational so there is no drug or device to try. The study is enrolling adults age 18 and older who are members of families with two or more living people diagnosed with Parkinson's.
Locations
- Emory University/ Wesley Woods Health Center, Atlanta, Georgia, United States
- University of Cincinnati, Cincinnati, Ohio, United States
- Portland VA Medical Center, Portland, Oregon, United States
- VA Puget Sound Health Care System, Seattle, Washington, United States
- University of Washington, Seattle, Washington, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. PaGeR looks for inherited genetic changes that increase the risk of Parkinson's or shape how the disease starts and progresses in families, with the goal of pointing to biological pathways for future tests or treatments. Researchers gather family histories and DNA samples from relatives in affected families and analyze genetic variants across those families, this is observational so there is no drug or device to try. The study is enrolling adults age 18 and older who are members of families with two or more living people diagnosed with Parkinson's.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 5 locations.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 17 years and 2 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
- How many visits does this trial involve?
- Enrollment in the study usually takes between one and two hours.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Blood draw (minimally invasive); Questionnaires & surveys (non-invasive); Thinking & memory tests (non-invasive). Confirm the full schedule with the study coordinator.