Reduce tremor using Medtronic Activa

Trial ID
NCT01581580
Official Title
Deep Brain Stimulation Surgery for Movement Disorders
Goal
Reduce tremor using Medtronic Activa
Phase
NA
Status
RECRUITING
Sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
Study Type
INTERVENTIONAL
Enrollment
200 participants
Conditions
Parkinson's Disease, Essential Tremor, Dystonia
Interventions
Medtronic Activa Tremor Control System, Deep Brain Stimulation

Plain-Language Summary

The goal is to reduce disabling movement problems like tremor, stiffness, slowness, or dystonic postures when medications are not controlling symptoms. It uses the Medtronic Activa Tremor Control System, a surgically implanted deep brain stimulation device that delivers continuous electrical pulses to targeted brain regions to quiet abnormal circuits that cause tremor and other motor issues, often improving symptoms and allowing lower levodopa doses or fewer on/off swings. To join, you must be 18 to 99, able to give informed consent, and have a diagnosis confirmed by the NIH movement disorders team of idiopathic Parkinson's not adequately controlled by meds, primary dystonia refractory to treatment, or essential tremor causing significant disability despite medication. People who cannot or will not give informed consent are excluded.

Locations

  • National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Frequently Asked Questions

What is this trial testing?
This trial is studying Medtronic Activa Tremor Control System. The goal is to reduce disabling movement problems like tremor, stiffness, slowness, or dystonic postures when medications are not controlling symptoms. It uses the Medtronic Activa Tremor Control System, a surgically implanted deep brain stimulation device that delivers continuous electrical pulses to targeted brain regions to quiet abnormal circuits that cause tremor and other motor issues, often improving symptoms and allowing lower levodopa doses or fewer on/off swings. To join, you must be 18 to 99, able to give informed consent, and have a diagnosis confirmed by the NIH movement disorders team of idiopathic Parkinson's not adequately controlled by meds, primary dystonia refractory to treatment, or essential tremor causing significant disability despite medication. People who cannot or will not give informed consent are excluded.
Who can participate?
Participants must be between 18 Years and 99 Years.
Where is this trial located?
This trial is recruiting at 1 location.
Does it cost anything to join?
No. There is no cost to participate. Study-related care and treatment are provided at no charge.
How long does the trial last?
This trial is estimated to last approximately 18 years and 3 months.

View on ClinicalTrials.gov