Parkinson's Trial NCT02760108
Detect inherited Parkinson gene variants
- Trial ID
- NCT02760108
- Official Title
- Parkinson's Families Project
- Goal
- Detect inherited Parkinson gene variants
- Status
- RECRUITING
- Sponsor
- University College, London
- Study Type
- OBSERVATIONAL
- Enrollment
- 2000 participants
- Conditions
- Parkinson's Disease, Parkinsonism
Summary For Families
The project aims to map familial and early-onset Parkinson's to spot patterns and risk factors that could point to genetic causes or guide future treatments. It is an observational program that collects clinical information and detailed family history from people with Parkinson's or parkinsonism and from their first and second degree relatives, both affected and unaffected, to look for those patterns. They are enrolling people aged 16 and older who have a clinical diagnosis of Parkinson's disease or parkinsonism and either have a first or second degree family member with Parkinson's/parkinsonism or had symptom onset before age 45, as well as first and second degree relatives of an index case. People who cannot give informed consent are not eligible.
Locations
- Royal Free London NHS Foundation Trust, London, United Kingdom
- University College London Hospitals NHS Foundation Trust, London, United Kingdom
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. The project aims to map familial and early-onset Parkinson's to spot patterns and risk factors that could point to genetic causes or guide future treatments. It is an observational program that collects clinical information and detailed family history from people with Parkinson's or parkinsonism and from their first and second degree relatives, both affected and unaffected, to look for those patterns. They are enrolling people aged 16 and older who have a clinical diagnosis of Parkinson's disease or parkinsonism and either have a first or second degree family member with Parkinson's/parkinsonism or had symptom onset before age 45, as well as first and second degree relatives of an index case. People who cannot give informed consent are not eligible.
- Who can participate?
- Participants must be at least 16 Years.
- Where is this trial located?
- This trial is recruiting at 2 locations.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 11 years and 9 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.