Anti-Parkinson medication for Parkinson's (NCT02994719)
Improve walking with Parkinson medication
- Trial ID
- NCT02994719
- Official Title
- Gait Pattern Analysis in Neurological Disease
- Goal
- Improve walking with Parkinson medication
- Status
- ACTIVE_NOT_RECRUITING
- Sponsor
- Beth Israel Deaconess Medical Center
- Study Type
- OBSERVATIONAL
- Enrollment
- 120 participants
- Conditions
- Parkinson's Disease, Parkinsonian Disorders, Atypical Parkinson Disease, Progressive Supranuclear Palsy, Multiple System Atrophy, Corticobasal Degeneration, Gait, Frontal, Huntington Disease
- Interventions
- Anti-Parkinson medication, Deep Brain Stimulation
Summary For Families
The goal is to map how Parkinson's and related disorders change walking, and to measure how anti-Parkinson medications and deep brain stimulation alter gait compared with healthy adults. Participants have their walking recorded while on their usual anti-Parkinson meds, which raise brain dopamine to improve movement, and for those with DBS the team may compare gait with stimulation on versus off, using motion analysis and sensors to quantify stride, speed, variability, and frontal gait features. Adults 18 to 85 are eligible, including people with Parkinson's or atypical parkinsonism who have at least two cardinal motor signs and healthy controls without walking complaints, with requirements for cognitive screening, safe mobility, and exclusions for other causes of parkinsonism, recent hospitalization, serious heart or lung disease, or participation in another interventional trial.
Locations
- Clinical Research Center BIDMC, Boston, Massachusetts, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Anti-Parkinson medication. The goal is to map how Parkinson's and related disorders change walking, and to measure how anti-Parkinson medications and deep brain stimulation alter gait compared with healthy adults. Participants have their walking recorded while on their usual anti-Parkinson meds, which raise brain dopamine to improve movement, and for those with DBS the team may compare gait with stimulation on versus off, using motion analysis and sensors to quantify stride, speed, variability, and frontal gait features. Adults 18 to 85 are eligible, including people with Parkinson's or atypical parkinsonism who have at least two cardinal motor signs and healthy controls without walking complaints, with requirements for cognitive screening, safe mobility, and exclusions for other causes of parkinsonism, recent hospitalization, serious heart or lung disease, or participation in another interventional trial.
- Who can participate?
- Participants must be between 18 Years and 85 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 11 years and 4 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
- How many visits does this trial involve?
- There is a first visit (no intervention) and an optional second visit for some subjects.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Brain surgery / implanted device (invasive). Confirm the full schedule with the study coordinator.