Predict treatment response from genetics
- Trial ID
- NCT03523052
- Official Title
- The Chinese Parkinson's Disease With SNCA Variants Registry
- Goal
- Predict treatment response from genetics
- Status
- RECRUITING
- Sponsor
- Xiangya Hospital of Central South University
- Study Type
- OBSERVATIONAL
- Enrollment
- 3000 participants
- Conditions
- Parkinson Disease
Plain-Language Summary
The registry aims to learn how variants in the SNCA gene, which affects alpha-synuclein, change Parkinson's symptoms, speed of progression, and responses to treatment so doctors can better predict outcomes and design targeted care or trials. It follows up to 3,000 people, collecting detailed clinical, genetic, and treatment data over time, including how symptoms evolve and how patients respond to standard therapies like levodopa. People of any age or sex who meet standard Parkinson's diagnostic criteria, such as the UK Brain Bank criteria, and who test positive for an SNCA variant are eligible, and because this is observational it does not change your current treatment.
Locations
- Xiangya Hospital of Central South University, Changsha, Hunan, China
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. The registry aims to learn how variants in the SNCA gene, which affects alpha-synuclein, change Parkinson's symptoms, speed of progression, and responses to treatment so doctors can better predict outcomes and design targeted care or trials. It follows up to 3,000 people, collecting detailed clinical, genetic, and treatment data over time, including how symptoms evolve and how patients respond to standard therapies like levodopa. People of any age or sex who meet standard Parkinson's diagnostic criteria, such as the UK Brain Bank criteria, and who test positive for an SNCA variant are eligible, and because this is observational it does not change your current treatment.
- Who can participate?
- Eligibility criteria vary. Check the full listing on ClinicalTrials.gov for detailed inclusion and exclusion criteria.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 10 years.