Parkinson's Trial NCT03523065

Predict symptoms and personalize care

Trial ID
NCT03523065
Official Title
The Chinese Parkinson's Disease With GBA Variants Registry
Goal
Predict symptoms and personalize care
Status
RECRUITING
Sponsor
Xiangya Hospital of Central South University
Study Type
OBSERVATIONAL
Enrollment
500 participants
Conditions
Parkinson Disease

Summary For Families

The goal is to learn how variants in the GBA gene affect Parkinson's symptoms, progression, and treatment responses so clinicians can better predict outcomes and personalize care. Instead of testing a drug, researchers are creating a registry that gathers genetic and clinical data and follows about 500 people over time, tracking things like symptom patterns and how patients respond to treatments such as levodopa. Enrollment is for people diagnosed with Parkinson's by standard criteria who have a confirmed GBA variant, the trial lists no age limits and accepts all sexes.

Locations

  • Xiangya Hospital of Central South University, Changsha, Hunan, China

Frequently Asked Questions

What is this trial testing?
This trial is studying an experimental treatment. The goal is to learn how variants in the GBA gene affect Parkinson's symptoms, progression, and treatment responses so clinicians can better predict outcomes and personalize care. Instead of testing a drug, researchers are creating a registry that gathers genetic and clinical data and follows about 500 people over time, tracking things like symptom patterns and how patients respond to treatments such as levodopa. Enrollment is for people diagnosed with Parkinson's by standard criteria who have a confirmed GBA variant, the trial lists no age limits and accepts all sexes.
Who can participate?
Eligibility criteria vary. Check the full listing on ClinicalTrials.gov for detailed inclusion and exclusion criteria.
Where is this trial located?
This trial is recruiting at 1 location.
Does it cost anything to join?
You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
How long does the trial last?
This trial is estimated to last approximately 10 years.
Can I leave the trial if I change my mind?
Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
Can my spouse or care partner come with me to visits?
In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
Will I get a placebo in this trial?
This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
What procedures are involved in this trial?
Based on the protocol, this trial involves: Questionnaires & surveys (non-invasive). Confirm the full schedule with the study coordinator.

Related Reading

View on ClinicalTrials.gov