Brain stimulation changes breathing function
- Trial ID
- NCT04058457
- Official Title
- Deep Brain Stimulation in Parkinson's Disease: Respiratory Testing
- Goal
- Brain stimulation changes breathing function
- Status
- RECRUITING
- Sponsor
- University of Oxford
- Study Type
- OBSERVATIONAL
- Enrollment
- 60 participants
- Conditions
- Parkinson Disease
- Interventions
- DBS
Plain-Language Summary
They're looking at whether deep brain stimulation changes breathing and other respiratory functions in people with Parkinson's, since stimulating brain regions that control movement can also affect swallowing, speech, and respiratory control. Participants scheduled for DBS will have breathing tests before and after surgery while staying on their usual Parkinson's medications, and DBS works by delivering targeted electrical pulses to specific brain areas to modify abnormal circuits that cause motor symptoms so researchers can observe any effects on respiration. Adults 18 and older who are fluent in English and planned for DBS surgery can join, while people who are pregnant, have an acute respiratory problem, or are in another trial that affects breathing are excluded; about 60 people will be enrolled.
Locations
- John Radcliffe Hospital, Oxford, Oxfordshire, United Kingdom
Frequently Asked Questions
- What is this trial testing?
- This trial is studying DBS. They're looking at whether deep brain stimulation changes breathing and other respiratory functions in people with Parkinson's, since stimulating brain regions that control movement can also affect swallowing, speech, and respiratory control. Participants scheduled for DBS will have breathing tests before and after surgery while staying on their usual Parkinson's medications, and DBS works by delivering targeted electrical pulses to specific brain areas to modify abnormal circuits that cause motor symptoms so researchers can observe any effects on respiration. Adults 18 and older who are fluent in English and planned for DBS surgery can join, while people who are pregnant, have an acute respiratory problem, or are in another trial that affects breathing are excluded; about 60 people will be enrolled.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 5 years and 4 months.