Brain stimulation improves stopping movements
- Trial ID
- NCT04061135
- Official Title
- Neurophysiological, Behavioral, and Cognitive Networks in Movement Disorders
- Goal
- Brain stimulation improves stopping movements
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- University of Alabama at Birmingham
- Study Type
- INTERVENTIONAL
- Enrollment
- 90 participants
- Conditions
- Movement Disorders
- Interventions
- Response Inhibition and Deep Brain Stimulation in Parkinson's disease
Plain-Language Summary
They want to map how deep brain stimulation changes the brain networks that control stopping or changing movements, like response inhibition, and how those changes relate to behavior and thinking in Parkinson's disease and essential tremor. People having DBS surgery will perform response inhibition tasks while researchers record brain activity and test how the implanted device's electrical pulses alter those signals and task performance; DBS delivers targeted electrical stimulation to deep brain regions to reduce motor symptoms and can modulate cognitive control circuits. Adults 18 and older with Parkinson's disease or essential tremor who are judged suitable for DBS surgery and can give informed consent and take part in the testing are eligible, while people who are not surgical candidates, cannot consent, are pregnant, or have not tried conservative medical management are excluded.
Locations
- University of Alabama at Birmingham, Birmingham, Alabama, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Response Inhibition and Deep Brain Stimulation in Parkinson's disease. They want to map how deep brain stimulation changes the brain networks that control stopping or changing movements, like response inhibition, and how those changes relate to behavior and thinking in Parkinson's disease and essential tremor. People having DBS surgery will perform response inhibition tasks while researchers record brain activity and test how the implanted device's electrical pulses alter those signals and task performance; DBS delivers targeted electrical stimulation to deep brain regions to reduce motor symptoms and can modulate cognitive control circuits. Adults 18 and older with Parkinson's disease or essential tremor who are judged suitable for DBS surgery and can give informed consent and take part in the testing are eligible, while people who are not surgical candidates, cannot consent, are pregnant, or have not tried conservative medical management are excluded.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 8 years and 7 months.