No intervention for Parkinson's (NCT04724941)
Discover who may develop Parkinson
- Trial ID
- NCT04724941
- Official Title
- Prodromal Alpha-Synuclein Screening in Parkinson's Disease Study
- Goal
- Discover who may develop Parkinson
- Status
- RECRUITING
- Sponsor
- University Hospital Schleswig-Holstein
- Study Type
- OBSERVATIONAL
- Enrollment
- 2000 participants
- Conditions
- Parkinson Disease
- Interventions
- No intervention
Summary For Families
The PASS-PD study aims to find people in the general population who are at higher risk of developing Parkinson's and to follow a risk-enriched group for five years, with careful attention to how early risk information is shared. It uses clinical assessments and biological markers to map different risk profiles, focus on non-movement symptoms, identify people likely to develop Parkinson's, and see whether markers help predict who will progress; no treatment is being tested. Some participants may be asked to give a spinal fluid sample for extra testing, but that part excludes people with bleeding problems or who take blood thinners. The study is looking for volunteers age 50 to 99 who do not have clinical Parkinson's now and who do not have other major nervous system or orthopedic conditions that would affect the testing.
Locations
- Department for Neurology, University of Kiel, Kiel, Germany
Frequently Asked Questions
- What is this trial testing?
- This trial is studying No intervention. The PASS-PD study aims to find people in the general population who are at higher risk of developing Parkinson's and to follow a risk-enriched group for five years, with careful attention to how early risk information is shared. It uses clinical assessments and biological markers to map different risk profiles, focus on non-movement symptoms, identify people likely to develop Parkinson's, and see whether markers help predict who will progress; no treatment is being tested. Some participants may be asked to give a spinal fluid sample for extra testing, but that part excludes people with bleeding problems or who take blood thinners. The study is looking for volunteers age 50 to 99 who do not have clinical Parkinson's now and who do not have other major nervous system or orthopedic conditions that would affect the testing.
- Who can participate?
- Participants must be between 50 Years and 99 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 6 years and 6 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
- How many visits does this trial involve?
- Participants will have an annual investigation at the Department for Neurology.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Walking & movement tests (non-invasive). Confirm the full schedule with the study coordinator.