Brain stimulation improves daily motivation
- Trial ID
- NCT05065151
- Official Title
- Understanding Motivation in Parkinson's Patients Through Neurophysiology
- Goal
- Brain stimulation improves daily motivation
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- University of California, San Francisco
- Study Type
- INTERVENTIONAL
- Enrollment
- 70 participants
- Conditions
- Parkinson Disease, Deep Brain Stimulation, Motivation
- Interventions
- Stimulation on, Stimulation off, Decision Making Task
Plain-Language Summary
The goal is to understand how deep brain stimulation changes motivation and decision-making in people with Parkinson's disease or dystonia, by linking choices to brain signals. Participants who already have a Medtronic Percept or RC+S DBS system implanted in the subthalamic nucleus (STN) or globus pallidus interna (GPi) will do decision-making tasks while researchers switch stimulation on and off and record neural activity, so we can see how the electrical pulses from DBS alter motivation-related brain circuits and behavior. The study seeks adults 18 and older who are at least one month post-DBS surgery with unilateral or bilateral Percept or RC+S implants, who do not have severe cognitive impairment (MoCA 20 or above) and are not pregnant.
Locations
- University of California San Francisco, San Francisco, California, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Stimulation on. The goal is to understand how deep brain stimulation changes motivation and decision-making in people with Parkinson's disease or dystonia, by linking choices to brain signals. Participants who already have a Medtronic Percept or RC+S DBS system implanted in the subthalamic nucleus (STN) or globus pallidus interna (GPi) will do decision-making tasks while researchers switch stimulation on and off and record neural activity, so we can see how the electrical pulses from DBS alter motivation-related brain circuits and behavior. The study seeks adults 18 and older who are at least one month post-DBS surgery with unilateral or bilateral Percept or RC+S implants, who do not have severe cognitive impairment (MoCA 20 or above) and are not pregnant.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 9 years and 1 month.