Dynamic cycling for Parkinson's (NCT05298150)
Reduce freezing with dynamic cycling
- Trial ID
- NCT05298150
- Official Title
- Remote Dynamic Cycling for the Customized Off-site Rehab in Parkinson's Disease
- Goal
- Reduce freezing with dynamic cycling
- Phase
- NA
- Status
- COMPLETED
- Sponsor
- VA Office of Research and Development
- Study Type
- INTERVENTIONAL
- Enrollment
- 72 participants
- Conditions
- Parkinson's Disease
- Interventions
- Dynamic cycling, Forced cycling
Summary For Families
The goal is to test whether remote dynamic or forced cycling can improve motor function and mobility in Parkinson's, especially slowness and walking difficulties. The approach uses a motor-assisted bicycle that moves your legs at a faster, steady cadence than you could produce on your own, a pattern thought to help retrain motor circuits and boost movement control, with sessions done off-site and monitored remotely. It is meant to be used alongside your usual Parkinson's medications, not as a replacement, so participants must be on a stable antiparkinsonian regimen for at least six months. The study is enrolling adults 18 and older with mild to moderate Parkinson's, Hoehn and Yahr stages I to III off medication, who have enough cognition to consent (MoCA 18 or higher) and no significant untreated cardiovascular issues, severe depression, anxiety, or atypical parkinsonism.
Locations
- Louis Stokes VA Medical Center, Cleveland, OH, Cleveland, Ohio, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Dynamic cycling. The goal is to test whether remote dynamic or forced cycling can improve motor function and mobility in Parkinson's, especially slowness and walking difficulties. The approach uses a motor-assisted bicycle that moves your legs at a faster, steady cadence than you could produce on your own, a pattern thought to help retrain motor circuits and boost movement control, with sessions done off-site and monitored remotely. It is meant to be used alongside your usual Parkinson's medications, not as a replacement, so participants must be on a stable antiparkinsonian regimen for at least six months. The study is enrolling adults 18 and older with mild to moderate Parkinson's, Hoehn and Yahr stages I to III off medication, who have enough cognition to consent (MoCA 18 or higher) and no significant untreated cardiovascular issues, severe depression, anxiety, or atypical parkinsonism.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 4 years.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- There is no placebo group. Everyone receives an active treatment; the study compares one treatment against another.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Wearable / at-home monitoring (non-invasive). Confirm the full schedule with the study coordinator.