Boost sleep recovery with tones
- Trial ID
- NCT05402488
- Official Title
- Exploring the Recovery Function of Sleep in Neurodegeneration - an Observational Cross-Sectional Study
- Goal
- Boost sleep recovery with tones
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- University of Zurich
- Study Type
- INTERVENTIONAL
- Enrollment
- 200 participants
- Conditions
- Neurodegenerative Diseases
- Interventions
- Auditory stimulation
Plain-Language Summary
The goal is to see whether deep, slow-wave sleep helps the brain recover from neurodegenerative diseases that involve abnormal protein build-up, and whether boosting that sleep can support protein clearance and memory. Participants wear a home EEG while gentle, timed auditory tones are played during sleep to amplify slow-wave activity, a noninvasive approach meant to strengthen sleep-dependent clearance and consolidation processes. Adults 18 and older who are either healthy or have a confirmed neurodegenerative disease with abnormal protein aggregation can join if they can use the ambulant EEG and hear the tones; people on opioids or benzodiazepines, with ear or skin issues that prevent electrode use, or who cannot follow study procedures are excluded.
Locations
- University Hospital Zurich, Neurology department, Zurich, Canton of Zurich, Switzerland
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Auditory stimulation. The goal is to see whether deep, slow-wave sleep helps the brain recover from neurodegenerative diseases that involve abnormal protein build-up, and whether boosting that sleep can support protein clearance and memory. Participants wear a home EEG while gentle, timed auditory tones are played during sleep to amplify slow-wave activity, a noninvasive approach meant to strengthen sleep-dependent clearance and consolidation processes. Adults 18 and older who are either healthy or have a confirmed neurodegenerative disease with abnormal protein aggregation can join if they can use the ambulant EEG and hear the tones; people on opioids or benzodiazepines, with ear or skin issues that prevent electrode use, or who cannot follow study procedures are excluded.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 3 years and 9 months.