Parkinson's Trial NCT05413291
Track movement disorder symptom progression
- Trial ID
- NCT05413291
- Official Title
- Natural History Protocol for Movement Disorders
- Goal
- Track movement disorder symptom progression
- Status
- RECRUITING
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
- Study Type
- OBSERVATIONAL
- Enrollment
- 4000 participants
- Conditions
- Movement Disorder, Tremor, Parkinson's Disease
Summary For Families
The goal is to map the natural history of movement disorders like Parkinson's and tremor, so researchers can see how symptoms and biological markers change over time and build better tests and treatments. The approach is observational, following participants with regular clinical assessments and data collection, which can include symptom ratings, medical history, and possibly imaging or biological samples to identify patterns and biomarkers. Anyone aged 2 and older who has or is suspected to have a movement disorder, or a family member of someone with a suspected disorder, and who can give consent or has a legally authorized representative can join, children under 2 are excluded.
Locations
- National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. The goal is to map the natural history of movement disorders like Parkinson's and tremor, so researchers can see how symptoms and biological markers change over time and build better tests and treatments. The approach is observational, following participants with regular clinical assessments and data collection, which can include symptom ratings, medical history, and possibly imaging or biological samples to identify patterns and biomarkers. Anyone aged 2 and older who has or is suspected to have a movement disorder, or a family member of someone with a suspected disorder, and who can give consent or has a legally authorized representative can join, children under 2 are excluded.
- Who can participate?
- Participants must be between 2 Years and 100 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 8 years and 2 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
- How many visits does this trial involve?
- Most participants will come to the NIH clinic for only 1 visit; some participants may be asked to return for a follow-up visit.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Blood draw (minimally invasive). Confirm the full schedule with the study coordinator.