Targeted brain stimulation reduces tremor
- Trial ID
- NCT05658302
- Official Title
- Circuit-Based Deep Brain Stimulation for Parkinson's Disease P1A2&3 Catalyst
- Goal
- Targeted brain stimulation reduces tremor
- Status
- RECRUITING
- Sponsor
- University of Minnesota
- Study Type
- OBSERVATIONAL
- Enrollment
- 30 participants
- Conditions
- Parkinson Disease
Plain-Language Summary
The goal is to map and use specific brain circuits to make deep brain stimulation more precise and effective for Parkinson's motor symptoms, so stimulation can reduce tremor, slowness, and stiffness while limiting side effects. The approach is observational: patients having routine DBS at the University of Minnesota will receive directional leads and a programmable implantable pulse generator with multiple independent current control, DBS delivers small electrical pulses to motor circuits, directional leads steer current toward helpful areas and independent current control shapes stimulation across contacts, and the protocol may include intraoperative recordings such as an ECoG strip. Looking for adults 21 and older with idiopathic Parkinson's who plan DBS surgery at UMN with those devices, people with other major neurological disorders, dementia, pregnancy, recent unsafe radiation exposure, or post-op complications that affect safety are excluded.
Locations
- University Of Minnesota, Minneapolis, Minnesota, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. The goal is to map and use specific brain circuits to make deep brain stimulation more precise and effective for Parkinson's motor symptoms, so stimulation can reduce tremor, slowness, and stiffness while limiting side effects. The approach is observational: patients having routine DBS at the University of Minnesota will receive directional leads and a programmable implantable pulse generator with multiple independent current control, DBS delivers small electrical pulses to motor circuits, directional leads steer current toward helpful areas and independent current control shapes stimulation across contacts, and the protocol may include intraoperative recordings such as an ECoG strip. Looking for adults 21 and older with idiopathic Parkinson's who plan DBS surgery at UMN with those devices, people with other major neurological disorders, dementia, pregnancy, recent unsafe radiation exposure, or post-op complications that affect safety are excluded.
- Who can participate?
- Participants must be at least 21 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 3 years and 11 months.